G J Peek, D Elbourne, M Mugford, R Tiruvoipati, A Wilson, E Allen, F Clemens, R Firmin, P Hardy, C Hibbert, N Jones, H Killer, M Thalanany, A Truesdale
OBJECTIVES: To determine the comparative effectiveness and cost-effectiveness of conventional ventilatory support versus extracorporeal membrane oxygenation (ECMO) for severe adult respiratory failure. DESIGN: A multicentre, randomised controlled trial with two arms. SETTING: The ECMO centre at Glenfield Hospital, Leicester, and approved conventional treatment centres and referring hospitals throughout the UK. PARTICIPANTS: Patients aged 18-65 years with severe, but potentially reversible, respiratory failure, defined as a Murray lung injury score > or = 3...
July 2010: Health Technology Assessment: HTA