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https://www.readbyqxmd.com/read/28716684/a-comparison-of-retrobulbar-and-two-peribulbar-regional-anesthetic-techniques-in-dog-cadavers
#1
Yael Shilo-Benjamini, Peter J Pascoe, Erik R Wisner, Nili Kahane, Philip H Kass, David J Maggs
OBJECTIVE: To compare injectate distribution and likelihood of regional anesthesia to the orbit following retrobulbar (RB) or peribulbar (PB) injections in dog cadavers. STUDY DESIGN: Randomized, masked study. ANIMALS: Twenty-four dog cadavers (aged 5.5-17 years, 2.0-36.3 kg). METHODS: Orbits underwent one of three injection techniques with bupivacaine 0.5% and iohexol (1:1): ventrolateral RB injection (1-2 mL; 15 orbits), medial canthal PB injection (2-8 mL; PB-1; 16 orbits), or dorsomedial and ventrolateral PB injections (each 1-4 mL; PB-2; 16 orbits)...
April 13, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28665780/viscoless-manual-small-incision-cataract-surgery-with-trabeculectomy
#2
Aparna Rao, Debananda Padhy, Gopinath Das, Sarada Sarangi
PURPOSE: To compare the efficacy of combined manual small incision cataract and glaucoma surgery with anterior chamber maintainer (ACM) alone versus that with intraoperative viscoelastics. METHODS: Hospital electronic medical records of patients who underwent small incision cataract and trabeculectomy and intraocular lens implantation without Mitomycin-C from 2014 to 2016 were identified from the hospital operation theater database for this retrospective, hospital-based comparative study...
June 30, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28633753/tumor-necrosis-factor-induced-alopecia-alternative-pathology-and-therapy
#3
Jeremy Udkoff, Philip R Cohen
Tumor necrosis factor (TNF) inhibitors are used to treat Crohn disease and psoriasis. Although they are typically well tolerated, adverse effects include the development of alopecia, and paradoxically, psoriatic lesions. We recently described a woman with Crohn disease who developed alopecia and scalp psoriasis during infliximab therapy. After discontinuing infliximab and beginning oral and topical therapies, her alopecia completely resolved. We compared our experience with that of the Craddock et al. who described a woman with Crohn disease and alopecia secondary to adalimumab therapy...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28405129/effect-of-addition-of-fentanyl-and-clonidine-to-local-anesthetic-solution-in-peribulbar-block
#4
Poonam Nehra, Vrinda Oza, Vandana Parmar, Pooja Fumakiya
OBJECTIVE: To compare the effect of addition of fentanyl and clonidine as adjuvants to bupivacaine and lignocaine in peribulbar block. METHODS: The study was conducted on 105 adult patients of either sex, of ASA grade I and II undergoing ophthalmic surgeries. Patients were randomly divided into 3 groups of 35 each. All the patients were given peribulbuar block with 5ml lignocaine 2% +3 ml bupivacaine 0.5% +1 ml hyaluronidase (250 IU). In addition to this 1 ml normal saline was added to Group S, 25 μg fentanyl to Group F and 25 μg clonidine to Group C...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28392642/the-contributory-roles-of-th17-lymphocyte-and-cytotoxic-t-lymphocyte-at-the-hair-bulge-region-as-well-as-the-hair-bulb-area-in-the-chronic-alopecia-areata-patients
#5
Jin-Woo Hong, Chae-Young Lee, Seung-Min Ha, Seung-Hwan Choi, Tae-Hoon Kim, Ki-Hoon Song, Ki-Ho Kim
BACKGROUND: Alopecia areata (AA) is a T cell-mediated autoimmune disease that targets hair follicles and interrupts hair regrowth. The microenvironment of the effector T cells and their related cytokines may affect immunopathogenesis around the hair bulb/bulge. OBJECTIVE: To determine the contributory roles of the effector T cell subsets and related cytokines to the pathogenesis of AA. METHODS: We investigated the correlation between histopathological grades and four clinical prognostic factors in 331 patients with AA, and analyzed the topography of T cell infiltrates and related cytokines around the hair bulb/bulge according to histopathological grades through immunohistochemical and double immunofluorescence studies on a subset of AA specimens...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28174153/a-prospective-randomised-double-masked-comparison-of-local-anaesthetic-agents-for-vitrectomy
#6
Ya-Li Zhou, Yao Tong, Yi-Xiao Wang, Pei-Quan Zhao, Zhao-Yang Wang
PURPOSE: To compare the intraoperative and postoperative clinical properties of 1% ropivacaine, 0.75% bupivacaine, 2% lidocaine and a mixture of 0.75% bupivacaine and 2% lidocaine (bupi+lido) administered for peribulbar anaesthesia during vitrectomy. METHODS: A total of 140 patients were randomly allocated to four groups. The time of onset of analgesia and akinesia was measured. The efficacy of anaesthesia, degree of postoperative pain and intraoperative and postoperative complications were recorded...
February 7, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28099337/phototoxic-maculopathy-induced-by-quartz-infrared-heat-lamp-a-clinical-case-report
#7
Xinhua Zheng, Ping Xie, Zizhong Hu, Weiwei Zhang, Kang Liang, Xiuying Wang, Qinghuai Liu
RATIONALE: A large proportion of the output of quartz infrared heat lamps is emitted as infrared radiation (IR). Retinal damage induced by IR-A and visible light on arc welders has been reported. However, case reports of retinal damage caused by quartz infrared heat lamps are rare. To the best of our knowledge, this is the first reported case of phototoxic maculopathy induced by quartz infrared heat lamps. PATIENT CONCERNS: We report a female with a 1-month history of progressive blurred vision and dysmorphopsia in her right eye after improper staring at the tubes of a quartz infrared heater...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28041966/different-roles-of-retinal-dopamine-in-albino-guinea-pig-myopia
#8
Junfeng Mao, Shuangzhen Liu
PURPOSE: To investigate whether the different role of ocular dopamine was involved in the myopic development between spontaneous myopia (SM) and form deprivation myopia (FDM) in albino guinea pigs. METHODS: 55 myopic animals were randomly divided into SM, Levodapa (L-DOPA), L-DOPA+carbidopa and vehicle. 70 non-myopic animals were randomly divided into normal control, FDM, L-DOPA+FDM, L-DOPA+carbidopa+FDM and vehicle. Once per day, for 14days, L-DOPA (10mg/kg) was injected intraperitoneally, and carbidopa (1μg) was injected at the same time into the peribulbar space of the right eye...
February 3, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/27930797/unusual-severe-interface-inflammation-after-uneventful-small-incision-lenticule-extraction-smile
#9
Damien Guindolet, Abdellatif Badaoui, Maud Elluard, Sophie Stephan, Serge Doan, Isabelle Cochereau, Eric E Gabison
PURPOSE: To describe a 40-year-old woman who complained of visual loss in her left eye 3 days after an uneventful bilateral myopic refractive surgery by small incision lenticule extraction (SMILE). METHODS: Case report. RESULTS: A 4 × 5 mm anterior central stromal infiltration was observed with moderate pain associated with decreased corneal sensitivity and neither discharge nor fluorescein staining. Bacterial and fungal smears and cultures from the SMILE interface were negative and local antibiotic ineffective...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27795795/cataract-surgery-with-intraocular-lens-implantation-in-children-aged-5-15-in-local-anaesthesia-visual-outcomes-and-complications
#10
Kagmeni Giles, Domngang Christelle, Bilong Yannick, Otto Herrmann Fricke, Peter Wiedemann
The aim of this study was to report feasibility, the visual outcomes and complications of pediatric cataract surgery with primary intraocular lens implantation in children aged 5 to15 years in local anesthesia. This retrospective interventional case series included 62 eyes from 50 children who underwent pediatrc cataract surgery with primary intraocular lens implantation at the Mana eye Clinic Nkongsamba between 2006 and 2015 Main outcome measures were: best-corrected post operative visual acuity, and intraoperative and postoperative complications...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27699252/safety-and-efficacy-of-the-jak-inhibitor-tofacitinib-citrate-in-patients-with-alopecia-areata
#11
Milène Kennedy Crispin, Justin M Ko, Brittany G Craiglow, Shufeng Li, Gautam Shankar, Jennifer R Urban, James C Chen, Jane E Cerise, Ali Jabbari, Mårten C G Winge, M Peter Marinkovich, Angela M Christiano, Anthony E Oro, Brett A King
BACKGROUND: Alopecia areata (AA) is an autoimmune disease characterized by hair loss mediated by CD8(+) T cells. There are no reliably effective therapies for AA. Based on recent developments in the understanding of the pathomechanism of AA, JAK inhibitors appear to be a therapeutic option; however, their efficacy for the treatment of AA has not been systematically examined. METHODS: This was a 2-center, open-label, single-arm trial using the pan-JAK inhibitor, tofacitinib citrate, for AA with >50% scalp hair loss, alopecia totalis (AT), and alopecia universalis (AU)...
September 22, 2016: JCI Insight
https://www.readbyqxmd.com/read/27644142/alopecia-universalis-in-a-dog-with-testicular-neoplasia
#12
Catherine A Outerbridge, Stephen D White, Verena K Affolter
OBJECTIVE: To describe a case of testicular neoplasia and alopecia universalis in a dog, and successful treatment of the latter with ciclosporin. ANIMAL: Twelve-year-old intact male wirehaired fox terrier. METHODS: Castration, skin biopsy for histopathology, lymphocyte immunophenotyping and clonality analysis of the canine T-cell receptor gamma locus (TCRγ) rearrangement. RESULTS: The dog presented with symmetrical generalized alopecia...
December 2016: Veterinary Dermatology
https://www.readbyqxmd.com/read/27641718/local-versus-general-anaesthesia-for-adults-undergoing-pars-plana-vitrectomy-surgery
#13
Ana Licina, Sharan Sidhu, Jing Xie, Crispin Wan
BACKGROUND: Vitrectomy surgery is one of the commonest ophthalmic procedures performed across the world. It may be performed using general or local anaesthesia encompassing regional or topical anaesthesia depending on a number of factors, including patient suitability, and patient, surgeon or anaesthetist preference. There have so far been no evidence-based recommendations on the best form of anaesthesia for this intervention. There is no clear collated evidence base as to the best type of anaesthesia to reduce harm, and provide best surgical conditions and optimal outcome for patients...
September 19, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27625562/a-comparison-of-vertical-and-transverse-sections-in-the-histological-diagnosis-of-alopecia-areata-scalp-biopsy-specimens
#14
Kanika Singh, Sonal Sharma, Usha Rani Singh, Sambit Nath Bhattacharya
CONTEXT: Both vertical and transverse sections are used for the diagnosis of alopecia areata. However when a single biopsy is submitted the pathologist has to decide which type is better. AIMS: To compare the diagnostic histological features in vertical and transverse sections in alopecia areata scalp biopsy specimens. SETTINGS AND DESIGN: Tertiary Care Hospital. Comparative Study. MATERIALS AND METHODS: A total of 30 patients were enrolled in the study...
July 2016: International Journal of Trichology
https://www.readbyqxmd.com/read/27554191/-amaurosis-and-contralateral-cranial-nerve-pairs-iii-and-vi-paralysis-after-peribulbar-block-case-report
#15
Fábio Caetano Oliveira Leme, Eduardo Toshiyuki Moro, Alexandre Alberto Fontana Ferraz
BACKGROUND AND OBJECTIVES: Peribulbar anesthesia (PBA) has emerged as a safer option compared with intraconal retrobulbar block. Still, PBA may not be considered without risk. Numerous complications have been described when performing this technique. This report aims to describe a rare case of amaurosis and contralateral paralysis while attempting to perform a PBA. CASE REPORT: Male patient, 75-year old, physical status ASA II, undergoing cataract surgery by phacoemulsification with intraocular lens implantation...
August 20, 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/27488158/purtscher-like-retinopathy-a-rare-complication-of-peribulbar-anesthesia
#16
Siddharth Narendran, V R Saravanan, Merlyn Pereira
Purtscher and Purtscher-like retinopathy is a distinctive retinal syndrome characterized by ischemic retinal whitening in a peripapillary pattern. We report a case of Purtscher-like retinopathy in a healthy 64-year-old man after a routine peribulbar anesthetic injection for cataract surgery. Although peribulbar anesthesia is considered to be a safer alternative to retrobulbar anesthesia, it has been associated with unusual but grave complications including central retinal artery occlusion.
June 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27385258/-e-ptfe-membrane-for-the-management-of-perforated-corneal-ulcer
#17
D Pahor, A Pahor
Purpose: To present the surgical management of perforated corneal ulcer using PRECLUDE® Pericardial Membrane, composed of expanded polytetrafluoroethylene (e-PTFE; GORE-TEX®), as an alternative surgical procedure in patients at high risk of graft rejections and to evaluate side effects for a prolonged period. Patients and Methods: The study included all patients who were admitted to our department and underwent surgical repair of perforated corneal ulcer with the e-PTFE membrane between 2010 and 2015. In total, 8 patients (8 eyes) were enrolled...
October 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27231416/preoperative-preparation-and-anesthesia-for-trabeculectomy
#18
REVIEW
Tom Eke
Preoperative preparation should improve the likelihood of successful trabeculectomy surgery. The team can reconsider the appropriateness of the proposed surgery, and steps can be taken to maximize the chance of a good outcome. For example, adjustments to anti-hypertensive or anti-coagulant medications may be made, and topical ocular medications adjusted. Choice of anesthesia technique is of particular relevance to the trabeculectomy patient. Some anesthesia techniques are more likely to have serious complications, and glaucoma patients may be at higher risk of some sight-threatening complications, because the optic nerve is already damaged and vulnerable...
January 2016: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/27216369/plasma-bupivacaine-concentrations-following-orbital-injections-in-cats
#19
Yael Shilo-Benjamini, Bruno H Pypendop, Georgina Newbold, Peter J Pascoe
OBJECTIVE: To determine plasma bupivacaine concentrations after retrobulbar or peribulbar injection of bupivacaine in cats. STUDY DESIGN: Randomized, crossover, experimental trial with a 2 week washout period. ANIMALS: Six adult healthy cats, aged 1-2 years, weighing 4.6 ± 0.7 kg. METHODS: Cats were sedated by intramuscular injection of dexmedetomidine (36-56 μg kg(-1)) and were administered a retrobulbar injection of bupivacaine (0...
January 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/27162743/ultrasound-comparison-of-diffusion-of-local-anesthetic-solution-after-a-peribulbar-and-a-sub-tenon-s-block-a-pilot-study
#20
Emile Calenda, Marc Muraine
No abstract text is available yet for this article.
2016: International Journal of Ophthalmology
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