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https://www.readbyqxmd.com/read/29053033/hyaluronidase-allergy-mimicking-orbital-cellulitis
#1
Nirav D Raichura, Md Shahid Alam, V V Jaichandran, Saurabh Mistry, Bipasha Mukherjee
PURPOSE: Hyaluronidase enzyme is a common additive with local anesthetic agent to facilitate faster permeation of the anesthetic in periocular tissues during ophthalmic surgery. We report a series of five subjects presenting with clinical features mimicking orbital cellulitis following peribulbar anesthesia and consequently diagnosed with hyaluronidase hypersensitivity. SETTING: The study was conducted at a tertiary eye care center in Southern India. DESIGN: It was a retrospective interventional case series...
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/29037862/artificial-urinary-sphincter-in-male-patients-with-spina-bifida-comparison-of-perioperative-and-functional-outcomes-between-bulbar-urethra-and-bladder-neck-cuff-placement
#2
Zine-Eddine Khene, Fanny Paret, Marie-Aime E Perrouin-Verbe, Thomas Prudhomme, Juliette Hascoet, Mathilde Nedelec, Jacques Kerdraon, Helene Menard, Magali Jezequel, Loïc Le Normand, Andrea Manunta, Xavier Game, Benoit Peyronnet
PURPOSE: To evaluate the perioperative and long-term functional outcomes of bladder neck and peribulbar cuff placement of an artificial urinary sphincter (AUS) in a population of adult male patients with spinal dysraphism. PATIENTS AND METHODS: A retrospective analysis of the French spina bifida (SB) network database was performed. Patients who underwent implantation of an AUS from January 1985 to November 2015 were selected and stratified into two groups according to cuff location: bladder neck vs...
October 13, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29020487/clinical-characteristics-and-prognostic-factors-in-ankylosing-spondylitis-associated-uveitis
#3
Ji Hwan Lee, Moonjung Choi, Tyler Hyung Taek Rim, Sung Chul Lee, Christopher Seungkyu Lee
PURPOSE: To identify the clinical features and prognostic factors of uveitis associated with ankylosing spondylitis (AS). METHODS: This retrospective, interventional case series study reviewed the medical records of 91 AS patients with uveitis. RESULTS: The characteristics of AS-associated uveitis included male preponderance (70%), average onset in the fourth decade, unilateral manifestation (87.9%), and vitreous involvement or retinal vascular leakage (36...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28944317/comparison-of-regional-vs-general-anesthesia-for-surgical-repair-of-open-globe-injuries-at-a-university-referral-center
#4
Andrew J McClellan, Jacquelyn J Daubert, Nidhi Relhan, Kimberly D Tran, Harry W Flynn, Steven Gayer
PURPOSE: This study compares the clinical features and physician selection of either Regional Anesthesia (peribulbar or retrobulbar block) with Monitored Anesthesia Care (RA-MAC) or General Anesthesia (GA) for open globe injury repair. DESIGN: A non-randomized, comparative, retrospective case series at a University Referral Center. PARTICIPANTS: All adult repairable open globe injuries receiving primary repair between January 1st, 2004 and December 31st, 2014 (11 years)...
May 2017: Ophthalmology retina
https://www.readbyqxmd.com/read/28868171/complication-of-peribulbar-block-brainstem-anaesthesia
#5
Leyla Kazancıoğlu, Şule Batçık, Hızır Kazdal, Ahmet Şen, Berrak Şekeryapan Gediz, Başar Erdivanlı
Peribulbar block is used to obtain anaesthesia and akinesia of the eye by injecting a local anaesthetic around the musclecone. A patient scheduled for cataract surgery received peribulbar block with 6 mL of 2% lidocaine hydrochloride. Following the injection, confusion, hypotension and dilatation of the contralateral pupil rapidly progressed to loss of consciousness and respiratory arrest. The patient was intubated and mechanically ventilated for 30 min. The patient regained her consciousness, was extubated and transferred to the intensive care unit for further follow-up...
August 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28840664/day-one-patch-off-visual-loss-due-to-retinal-ischaemic-injury-can-we-blame-sub-tenon-s-or-peribulbar-anaesthesia
#6
EDITORIAL
Fred K Chen
No abstract text is available yet for this article.
August 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28724815/efficacy-and-safety-of-intraoperative-intracameral-mydriasis-in-manual-small-incision-cataract-surgery-a-randomized-controlled-trial
#7
K Ajay, Srinivasan Saranya, Divya Dabir Sundaresh, H R Hithashree, B C Hemalatha, Malavika Krishnaswamy, Sathyendranath B Shetty
PURPOSE: The purpose of this study is to assess the efficacy and safety of intracameral mydriatic solution, as compared to preoperative topical mydriatics, in patients undergoing manual small incision cataract surgery (MSICS) under peribulbar anesthesia. To assess the sustainability of intracameral mydriasis in MSICS by monitoring pupil size at specific junctures during the surgery. METHODS: This trial recruited 127 patients, who underwent MSICS under peribulbar block...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28716684/a-comparison-of-retrobulbar-and-two-peribulbar-regional-anesthetic-techniques-in-dog-cadavers
#8
Yael Shilo-Benjamini, Peter J Pascoe, Erik R Wisner, Nili Kahane, Philip H Kass, David J Maggs
OBJECTIVE: To compare injectate distribution and likelihood of regional anesthesia to the orbit following retrobulbar (RB) or peribulbar (PB) injections in dog cadavers. STUDY DESIGN: Randomized, masked study. ANIMALS: Twenty-four dog cadavers (aged 5.5-17 years, 2.0-36.3 kg). METHODS: Orbits underwent one of three injection techniques with bupivacaine 0.5% and iohexol (1:1): ventrolateral RB injection (1-2 mL; 15 orbits), medial canthal PB injection (2-8 mL; PB-1; 16 orbits), or dorsomedial and ventrolateral PB injections (each 1-4 mL; PB-2; 16 orbits)...
April 13, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28665780/viscoless-manual-small-incision-cataract-surgery-with-trabeculectomy
#9
Aparna Rao, Debananda Padhy, Gopinath Das, Sarada Sarangi
PURPOSE: To compare the efficacy of combined manual small incision cataract and glaucoma surgery with anterior chamber maintainer (ACM) alone versus that with intraoperative viscoelastics. METHODS: Hospital electronic medical records of patients who underwent small incision cataract and trabeculectomy and intraocular lens implantation without Mitomycin-C from 2014 to 2016 were identified from the hospital operation theater database for this retrospective, hospital-based comparative study...
June 30, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28633753/tumor-necrosis-factor-induced-alopecia-alternative-pathology-and-therapy
#10
Jeremy Udkoff, Philip R Cohen
Tumor necrosis factor (TNF) inhibitors are used to treat Crohn disease and psoriasis. Although they are typically well tolerated, adverse effects include the development of alopecia, and paradoxically, psoriatic lesions. We recently described a woman with Crohn disease who developed alopecia and scalp psoriasis during infliximab therapy. After discontinuing infliximab and beginning oral and topical therapies, her alopecia completely resolved. We compared our experience with that of the Craddock et al. who described a woman with Crohn disease and alopecia secondary to adalimumab therapy...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28405129/effect-of-addition-of-fentanyl-and-clonidine-to-local-anesthetic-solution-in-peribulbar-block
#11
Poonam Nehra, Vrinda Oza, Vandana Parmar, Pooja Fumakiya
OBJECTIVE: To compare the effect of addition of fentanyl and clonidine as adjuvants to bupivacaine and lignocaine in peribulbar block. METHODS: The study was conducted on 105 adult patients of either sex, of ASA grade I and II undergoing ophthalmic surgeries. Patients were randomly divided into 3 groups of 35 each. All the patients were given peribulbuar block with 5ml lignocaine 2% +3 ml bupivacaine 0.5% +1 ml hyaluronidase (250 IU). In addition to this 1 ml normal saline was added to Group S, 25 μg fentanyl to Group F and 25 μg clonidine to Group C...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28392642/the-contributory-roles-of-th17-lymphocyte-and-cytotoxic-t-lymphocyte-at-the-hair-bulge-region-as-well-as-the-hair-bulb-area-in-the-chronic-alopecia-areata-patients
#12
Jin-Woo Hong, Chae-Young Lee, Seung-Min Ha, Seung-Hwan Choi, Tae-Hoon Kim, Ki-Hoon Song, Ki-Ho Kim
BACKGROUND: Alopecia areata (AA) is a T cell-mediated autoimmune disease that targets hair follicles and interrupts hair regrowth. The microenvironment of the effector T cells and their related cytokines may affect immunopathogenesis around the hair bulb/bulge. OBJECTIVE: To determine the contributory roles of the effector T cell subsets and related cytokines to the pathogenesis of AA. METHODS: We investigated the correlation between histopathological grades and four clinical prognostic factors in 331 patients with AA, and analyzed the topography of T cell infiltrates and related cytokines around the hair bulb/bulge according to histopathological grades through immunohistochemical and double immunofluorescence studies on a subset of AA specimens...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28174153/a-prospective-randomised-double-masked-comparison-of-local-anaesthetic-agents-for-vitrectomy
#13
RANDOMIZED CONTROLLED TRIAL
Ya-Li Zhou, Yao Tong, Yi-Xiao Wang, Pei-Quan Zhao, Zhao-Yang Wang
PURPOSE: To compare the intraoperative and postoperative clinical properties of 1% ropivacaine, 0.75% bupivacaine, 2% lidocaine and a mixture of 0.75% bupivacaine and 2% lidocaine (bupi+lido) administered for peribulbar anaesthesia during vitrectomy. METHODS: A total of 140 patients were randomly allocated to four groups. The time of onset of analgesia and akinesia was measured. The efficacy of anaesthesia, degree of postoperative pain and intraoperative and postoperative complications were recorded...
August 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28099337/phototoxic-maculopathy-induced-by-quartz-infrared-heat-lamp-a-clinical-case-report
#14
Xinhua Zheng, Ping Xie, Zizhong Hu, Weiwei Zhang, Kang Liang, Xiuying Wang, Qinghuai Liu
RATIONALE: A large proportion of the output of quartz infrared heat lamps is emitted as infrared radiation (IR). Retinal damage induced by IR-A and visible light on arc welders has been reported. However, case reports of retinal damage caused by quartz infrared heat lamps are rare. To the best of our knowledge, this is the first reported case of phototoxic maculopathy induced by quartz infrared heat lamps. PATIENT CONCERNS: We report a female with a 1-month history of progressive blurred vision and dysmorphopsia in her right eye after improper staring at the tubes of a quartz infrared heater...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28041966/different-roles-of-retinal-dopamine-in-albino-guinea-pig-myopia
#15
Junfeng Mao, Shuangzhen Liu
PURPOSE: To investigate whether the different role of ocular dopamine was involved in the myopic development between spontaneous myopia (SM) and form deprivation myopia (FDM) in albino guinea pigs. METHODS: 55 myopic animals were randomly divided into SM, Levodapa (L-DOPA), L-DOPA+carbidopa and vehicle. 70 non-myopic animals were randomly divided into normal control, FDM, L-DOPA+FDM, L-DOPA+carbidopa+FDM and vehicle. Once per day, for 14days, L-DOPA (10mg/kg) was injected intraperitoneally, and carbidopa (1μg) was injected at the same time into the peribulbar space of the right eye...
February 3, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/27930797/unusual-severe-interface-inflammation-after-uneventful-small-incision-lenticule-extraction-smile
#16
Damien Guindolet, Abdellatif Badaoui, Maud Elluard, Sophie Stephan, Serge Doan, Isabelle Cochereau, Eric E Gabison
PURPOSE: To describe a 40-year-old woman who complained of visual loss in her left eye 3 days after an uneventful bilateral myopic refractive surgery by small incision lenticule extraction (SMILE). METHODS: Case report. RESULTS: A 4 × 5 mm anterior central stromal infiltration was observed with moderate pain associated with decreased corneal sensitivity and neither discharge nor fluorescein staining. Bacterial and fungal smears and cultures from the SMILE interface were negative and local antibiotic ineffective...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27795795/cataract-surgery-with-intraocular-lens-implantation-in-children-aged-5-15-in-local-anaesthesia-visual-outcomes-and-complications
#17
Kagmeni Giles, Domngang Christelle, Bilong Yannick, Otto Herrmann Fricke, Peter Wiedemann
The aim of this study was to report feasibility, the visual outcomes and complications of pediatric cataract surgery with primary intraocular lens implantation in children aged 5 to15 years in local anesthesia. This retrospective interventional case series included 62 eyes from 50 children who underwent pediatrc cataract surgery with primary intraocular lens implantation at the Mana eye Clinic Nkongsamba between 2006 and 2015 Main outcome measures were: best-corrected post operative visual acuity, and intraoperative and postoperative complications...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27699252/safety-and-efficacy-of-the-jak-inhibitor-tofacitinib-citrate-in-patients-with-alopecia-areata
#18
Milène Kennedy Crispin, Justin M Ko, Brittany G Craiglow, Shufeng Li, Gautam Shankar, Jennifer R Urban, James C Chen, Jane E Cerise, Ali Jabbari, Mårten C G Winge, M Peter Marinkovich, Angela M Christiano, Anthony E Oro, Brett A King
BACKGROUND: Alopecia areata (AA) is an autoimmune disease characterized by hair loss mediated by CD8(+) T cells. There are no reliably effective therapies for AA. Based on recent developments in the understanding of the pathomechanism of AA, JAK inhibitors appear to be a therapeutic option; however, their efficacy for the treatment of AA has not been systematically examined. METHODS: This was a 2-center, open-label, single-arm trial using the pan-JAK inhibitor, tofacitinib citrate, for AA with >50% scalp hair loss, alopecia totalis (AT), and alopecia universalis (AU)...
September 22, 2016: JCI Insight
https://www.readbyqxmd.com/read/27644142/alopecia-universalis-in-a-dog-with-testicular-neoplasia
#19
Catherine A Outerbridge, Stephen D White, Verena K Affolter
OBJECTIVE: To describe a case of testicular neoplasia and alopecia universalis in a dog, and successful treatment of the latter with ciclosporin. ANIMAL: Twelve-year-old intact male wirehaired fox terrier. METHODS: Castration, skin biopsy for histopathology, lymphocyte immunophenotyping and clonality analysis of the canine T-cell receptor gamma locus (TCRγ) rearrangement. RESULTS: The dog presented with symmetrical generalized alopecia...
December 2016: Veterinary Dermatology
https://www.readbyqxmd.com/read/27641718/local-versus-general-anaesthesia-for-adults-undergoing-pars-plana-vitrectomy-surgery
#20
Ana Licina, Sharan Sidhu, Jing Xie, Crispin Wan
BACKGROUND: Vitrectomy surgery is one of the commonest ophthalmic procedures performed across the world. It may be performed using general or local anaesthesia encompassing regional or topical anaesthesia depending on a number of factors, including patient suitability, and patient, surgeon or anaesthetist preference. There have so far been no evidence-based recommendations on the best form of anaesthesia for this intervention. There is no clear collated evidence base as to the best type of anaesthesia to reduce harm, and provide best surgical conditions and optimal outcome for patients...
September 19, 2016: Cochrane Database of Systematic Reviews
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