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https://www.readbyqxmd.com/read/28069073/quantification-of-postural-stability-in-minimally-disabled-multiple-sclerosis-patients-by-means-of-dynamic-posturography-an-observational-study
#1
Lucia Grassi, Stefano Rossi, Valeria Studer, Gessica Vasco, Caterina Motta, Fabrizio Patanè, Enrico Castelli, Silvia Rossi, Paolo Cappa
BACKGROUND: Multiple Sclerosis (MS) is a widespread progressive neurologic disease with consequent impairments in daily activities. Disorders of balance are frequent and equilibrium tests are potentially useful to quantify disability and to verify treatment effectiveness. The fair sensitivity of the widely used not-perturbed tests to detect balance disturbances in MS patients have prompted the development of mechatronic systems capable to impose known equilibrium perturbations, in order to challenge the balance control and, consequently, to better assess the level of impairment...
January 10, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28068884/evaluation-of-protein-spectra-cluster-analysis-for-streptococcus-spp-identification-from-various-swine-clinical-samples
#2
Carlos E C Matajira, Luisa Z Moreno, Vasco T M Gomes, Ana Paula S Silva, Renan E Mesquita, Daniela S Doto, Franco F Calderaro, Fernando N de Souza, Ana Paula G Christ, Maria Inês Z Sato, Andrea M Moreno
Traditional microbiological methods enable genus-level identification of Streptococcus spp. isolates. However, as the species of this genus show broad phenotypic variation, species-level identification or even differentiation within the genus is difficult. Herein we report the evaluation of protein spectra cluster analysis for the identification of Streptococcus species associated with disease in swine by means of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). A total of 250 S...
January 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28045122/mirsig-a-consensus-based-network-inference-methodology-to-identify-pan-cancer-mirna-mirna-interaction-signatures
#3
Joseph J Nalluri, Debmalya Barh, Vasco Azevedo, Preetam Ghosh
Decoding the patterns of miRNA regulation in diseases are important to properly realize its potential in diagnostic, prog- nostic, and therapeutic applications. Only a handful of studies computationally predict possible miRNA-miRNA interactions; hence, such interactions require a thorough investigation to understand their role in disease progression. In this paper, we design a novel computational pipeline to predict the common signature/core sets of miRNA-miRNA interactions for different diseases using network inference algorithms on the miRNA-disease expression profiles; the individual predictions of these algorithms were then merged using a consensus-based approach to predict miRNA-miRNA associations...
January 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28026885/alexithymia-and-emotional-processing-a-mediation-model
#4
Ana Nunes da Silva, António Branco Vasco, Jeanne C Watson
OBJECTIVE: Although alexithymia has been associated with difficulties in emotional regulation, both constructs are complex and this association remains unclear. This research attempts to study the relation between both constructs to identify better ways to guide clinical intervention. METHOD: Emotion awareness, differentiation, and regulation were tested as mediators of the associations between alexithymia and severity of symptoms. The model was tested in a clinical (121 participants) and a nonclinical sample (188 participants)...
December 27, 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28002871/recommendations-of-the-essr-arthritis-subcommittee-on-ultrasonography-in-inflammatory-joint-disease
#5
Athena Plagou, James Teh, Andrew J Grainger, Claudia Schueller-Weidekamm, Iwona Sudoł-Szopińska, Winston Rennie, Gunnar Åström, Antoine Feydy, Chiara Giraudo, Henri Guerini, Giuseppe Guglielmi, Amanda Isaac, Lennart Jans, Anne Grethe Jurik, Franz Kainberger, Mario Maas, Carlo Martinoli, Vasco V Mascarenhas, Falk Miese, Philip O'Connor, Edwin H Oei, Mikkel Østergaard, Philippe Peetrons, Hannes Platzgummer, Monique Reijnierse, Philip Robinson, Mitja Rupreht, Paolo Simoni, Marius C Wick, Anna Zejden, Andrea S Klauser
This article presents the recommendations of the European Society of Musculoskeletal Radiology Arthritis Subcommittee on the use of ultrasonography (US) in rheumatic disease, focused on the examination of joints in the adult population. The recommended examination technique and protocols used in a radiologic work-up are discussed. The main US features that can lead to a final diagnosis in the most common rheumatic diseases are addressed. The differential diagnosis that should be considered at image interpretation is presented...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/27994108/prevalence-of-and-factors-associated-with-nephropathy-in-diabetic-patients-attending-an-outpatient-clinic-in-harare-zimbabwe
#6
Pasipanodya Ian Machingura, Vasco Chikwasha, Parmenas Nelson Okwanga, Exnevia Gomo
There is limited information on the burden of diabetic nephropathy in developing countries. This study aimed to determine the prevalence of and factors associated with nephropathy among diabetic patients attending an outpatient clinic in Harare, Zimbabwe. In an analytical cross-sectional study, diabetic patients were consecutively enrolled and a questionnaire administered, clinical assessment conducted, and blood samples collected for human immunodeficiency virus testing and measurement of lipids, creatinine, fructosamine, and glycosylated hemoglobin levels...
December 19, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27989819/detachment-of-the-fucoxanthin-chlorophyll-a-c-binding-protein-fcp-antenna-is-not-involved-in-the-acclimative-regulation-of-photoprotection-in-the-pennate-diatom-phaeodactylum-tricornutum
#7
Vasco Giovagnetti, Alexander V Ruban
When grown under intermittent light (IL), the pennate diatom Phaeodactylum tricornutum forms 'super' non-photochemical fluorescence quenching (NPQ) in response to excess light. The current model of diatom NPQ mechanism involves two quenching sites, one of which detaches from photosystem II reaction centres (RCIIs) and aggregates into oligomeric complexes. Here we addressed how antenna reorganisation controls NPQ kinetics in P. tricornutum cells grown under continuous light (CL) and IL. Overall, IL acclimation induced: (i) reorganisation of chloroplasts, containing greater pigment pools without a strongly enhanced operation of the xanthophyll cycle, and (ii) 'super NPQ' causing a remarkable reduction of the chlorophyll excited state lifetime at Fm'...
December 16, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27982252/standard-operating-procedure-implementation-critical-analysis-and-validation-in-the-audiology-department-at-cesteh-fiocruz
#8
Anelisse Vasco Mascarenhas de Freitas, Elinaldo Leite Quixabeiro, Geórgia Rosangela Soares Luz, Viviane Moreira Franco, Viviane Fontes Dos Santos
Purpose: Evaluate three standard operational procedures (SOPs), regarding the application of the brainstem auditory evoked potential (BAEP) test, implemented by the Audiology Department of the Center for Studies in Occupational Health and Human Ecology (CESTEH) through the application of a questionnaire and to verify whether the SOPs are effective and assess the necessity for improvement. Methods: The study was conducted in three phases: in the first phase, eight speech-language pathologists and seven physicians, with no experience in BAEP, were instructed to read and perform each SOP, eventually all individuals evaluated the SOPs by responding to a questionnaire; in the second phase, the questionnaires were analyzed and the three SOP texts were reviewed; in the third phase, nine speech-language pathologists and six physicians, also with no experience in BAEP, read and re-evaluated the reviewed SOPs through a questionnaire...
November 2016: CoDAS
https://www.readbyqxmd.com/read/27979735/molecular-epidemiology-of-corynebacterium-pseudotuberculosis-isolated-from-horses-in-california
#9
Dionei J Haas, Elaine M S Dorneles, Sharon J Spier, Scott P Carroll, Judy Edman, Vasco A Azevedo, Marcos B Heinemann, Andrey P Lage
Corynebacterium pseudotuberculosis biovar Equi is an important pathogen of horses. It is increasing in frequency in the United States, and is responsible for various clinical forms of infection, including external abscesses, internal abscesses of the abdominal or thoracic cavities, and ulcerative lymphangitis. The host/pathogen factors dictating the form or severity of infection are currently unknown. Our recent investigations have shown that genotyping C. pseudotuberculosis isolates using enterobacterial repetitive intergenic consensus (ERIC)-PCR is useful for understanding the evolutionary genetics of the species as well for molecular epidemiology studies...
December 12, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27970046/tct-669-valve-in-valve-in-small-surgical-valves-predictors-for-survival-and-elevated-post-procedural-gradients-insights-from-the-valve-in-valve-international-data-vivid-registry
#10
Matheus Simonato Dos Santos, Mohamed Abdel-Wahab, David Hildick-Smith, John Webb, Yaron Arbel, Hafid Amrane, Brian Whisenant, Matthew Miller, Marco Agrifoglio, Stefano Salizzoni, Patrizia Presbitero, Christian Frerker, Vasco Gama Ribeiro, Helene Eltchaninoff, Arend de Weger, Alfredo Cerillo, Ariel Finkelstein, Luca Testa, Tobias Zeus, Claudia Fiorina, Piotr Chodor, Dan Ioanes, Neil Moat, Danny Dvir
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969782/tct-428-bioresorbable-coronary-devices-in-clinical-practice-6-month-results-of-the-prospective-repara-registry
#11
Felipe Hernandez, Eduardo Pinar Bermudez, Eduardo Molina, Jose Diaz, Neus Salvatella, Juan Carlos Fernández, Hipolito Gutierrez, Ramon Lopez Palop, Xavier Carrillo, Javier Zueco, Joan Antoni Gomez Hospital, Andres Iñiguez, Pedro Canas da Silva, Cristobal Urbano, Ramiro Trillo, Amparo Benedicto, Armando Perez de Prado, Vasco Gama Ribeiro, Henrique Gabriel, Pablo Salinas, Juan Sanchis Fores, Jose Rumoroso, Pablo Pinon, Pablo Avanzas, Jose Ramon Lopez Minguez, Monica Masotti, Raul Moreno, Iñigo Lozano
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969755/tct-403-bioresorbable-coronary-devices-in-bifurcations-immediate-and-6-month-results-of-the-repara-registry
#12
Felipe Hernandez, Jose M de la Torre Hernandez, Bruno Garcia, Jose Rumoroso, Ramiro Trillo, Armando Perez de Prado, Eduardo Molina, Raul Moreno, Jose Diaz, Ivan Gomez Blazquez, Hipolito Gutierrez, Pedro Canas da Silva, Vasco Gama Ribeiro
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27936462/sinu-virus-a-novel-and-divergent-orthomyxovirus-related-to-members-of-the-genus-thogotovirus-isolated-from-mosquitoes-in-colombia
#13
María Angélica Contreras-Gutiérrez, Marcio R T Nunes, Hilda Guzman, Sandra Uribe, Juan Carlos Gallego Gómez, Juan David Suaza Vasco, Jedson F Cardoso, Vsevolod L Popov, Steven G Widen, Thomas G Wood, Nikos Vasilakis, Robert B Tesh
The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six distinct ORFs encoding the following genes: PB2 (Segment 1), PB1, (Segment 2), PA protein (Segment 3), envelope GP gene (Segment 4), the NP (Segment 5), and M-like gene (Segment 6)...
January 15, 2017: Virology
https://www.readbyqxmd.com/read/27936048/linear-in-the-parameters-oblique-least-squares-lols-provides-more-accurate-estimates-of-density-dependent-survival
#14
Vasco M N C S Vieira, Aschwin H Engelen, Oscar R Huanel, Marie-Laure Guillemin
Survival is a fundamental demographic component and the importance of its accurate estimation goes beyond the traditional estimation of life expectancy. The evolutionary stability of isomorphic biphasic life-cycles and the occurrence of its different ploidy phases at uneven abundances are hypothesized to be driven by differences in survival rates between haploids and diploids. We monitored Gracilaria chilensis, a commercially exploited red alga with an isomorphic biphasic life-cycle, having found density-dependent survival with competition and Allee effects...
2016: PloS One
https://www.readbyqxmd.com/read/27933239/impact-of-bowel-resection-margins-in-node-negative-colon-cancer
#15
Ricardo Rocha, Rui Marinho, David Aparício, Marta Fragoso, Marta Sousa, António Gomes, Carlos Leichsenring, Carla Carneiro, Vasco Geraldes, Vítor Nunes
PURPOSE: Surgical intestinal resection margins in colon cancer are a longstanding debate in terms the optimal distance between the tumor and the colonic section line. The aim of this study is to define the oncological outcomes in relation to surgical margins, measured in terms or recurrence rate, time-to-recurrence, disease-free survival and overall survival in a population of node negative colon cancer patients. METHODS: We conducted a retrospective observational longitudinal single institution study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27931189/adaptation-of-propionibacterium-freudenreichii-to-long-term-survival-under-gradual-nutritional-shortage
#16
Flavia Figueira Aburjaile, Marine Rohmer, Hugues Parrinello, Marie-Bernadette Maillard, Eric Beaucher, Gwénaële Henry, Aurélie Nicolas, Marie-Noëlle Madec, Anne Thierry, Sandrine Parayre, Stéphanie-Marie Deutsch, Muriel Cocaign-Bousquet, Anderson Miyoshi, Vasco Azevedo, Yves Le Loir, Hélène Falentin
BACKGROUND: Propionibacterium freudenreichii is an Actinobacterium widely used in the dairy industry as a ripening culture for Swiss-type cheeses, for vitamin B12 production and some strains display probiotic properties. It is reportedly a hardy bacterium, able to survive the cheese-making process and digestive stresses. RESULTS: During this study, P. freudenreichii CIRM-BIA 138 (alias ITG P9), which has a generation time of five hours in Yeast Extract Lactate medium at 30 °C under microaerophilic conditions, was incubated for 11 days (9 days after entry into stationary phase) in a culture medium, without any adjunct during the incubation...
December 8, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27912148/anti-cancer-effect-of-lactic-acid-bacteria-expressing-antioxidant-enzymes-or-il-10-in-a-colorectal-cancer-mouse-model
#17
Silvina Del Carmen, Alejandra de Moreno de LeBlanc, Romina Levit, Vasco Azevedo, Philippe Langella, Luis G Bermúdez-Humarán, Jean Guy LeBlanc
The association between inflammatory bowel diseases and colorectal cancer is well documented. The genetic modification of lactic acid bacteria as a tool to increase the anti-inflammatory potential of these microorganisms has also been demonstrated. Thus the aim of the present work was to evaluate the anti-cancer potential of different genetically modified lactic acid bacteria (GM-LAB) producing antioxidant enzymes (catalase or superoxide dismutase) or the anti-inflammatory cytokine IL-10 (protein or DNA delivery) using a chemical induced colon cancer murine model...
January 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27906905/description-of-13-infants-born-during-october-2015-january-2016-with-congenital-zika-virus-infection-without-microcephaly-at-birth-brazil
#18
Vanessa van der Linden, André Pessoa, William Dobyns, A James Barkovich, Hélio van der Linden Júnior, Epitacio Leite Rolim Filho, Erlane Marques Ribeiro, Mariana de Carvalho Leal, Pablo Picasso de Araújo Coimbra, Maria de Fátima Viana Vasco Aragão, Islane Verçosa, Camila Ventura, Regina Coeli Ramos, Danielle Di Cavalcanti Sousa Cruz, Marli Tenório Cordeiro, Vivian Maria Ribeiro Mota, Mary Dott, Christina Hillard, Cynthia A Moore
Congenital Zika virus infection can cause microcephaly and severe brain abnormalities (1). Congenital Zika syndrome comprises a spectrum of clinical features (2); however, as is the case with most newly recognized teratogens, the earliest documented clinical presentation is expected to be the most severe. Initial descriptions of the effects of in utero Zika virus infection centered prominently on the finding of congenital microcephaly (3). To assess the possibility of clinical presentations that do not include congenital microcephaly, a retrospective assessment of 13 infants from the Brazilian states of Pernambuco and Ceará with normal head size at birth and laboratory evidence of congenital Zika virus infection was conducted...
December 2, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27900604/assessment-of-interstitial-lung-disease-in-sj%C3%A3-gren-s-syndrome-by-lung-ultrasound-a-pilot-study-of-correlation-with-high-resolution-chest-tomography
#19
Pablo Guisado Vasco, Gonzalo de Luna Cardenal, Isabel Martín Garrido, José Manuel Luque Pinilla, Guadalupe Fraile Rodríguez, Juan José Nava Mateo, Daniel Carnevalli Ruiz
The background of this study is to assess the accuracy of lung ultrasound (LUS) to diagnose interstitial lung disease (ILD) in Sjögren's syndrome (Sjs), in patients who have any alterations in pulmonary function tests (PFT) or respiratory symptoms. LUS was correlated with chest tomography (hrCT), considering it as the imaging gold standard technique to diagnose ILD. This is a pilot, multicenter, cross-sectional, and consecutive-case study. The inclusion criteria are ≥18 years old, Signs and symptoms: according to ACEG 2002 criteria, respiratory symptoms (dyspnea, cough), or any alterations in PFR...
November 29, 2016: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/27865673/a-rare-cause-of-acute-coronary-syndrome-kounis-syndrome
#20
João Almeida, Sara Ferreira, Joana Malheiro, Paulo Fonseca, Daniel Caeiro, Adelaide Dias, José Ribeiro, Vasco Gama
Kounis syndrome is an acute coronary syndrome in the context of a hypersensitivity reaction. The main pathophysiological mechanism appears to be coronary vasospasm. We report the case of a patient with a history of allergy to quinolones, who was given ciprofloxacin before an elective surgical procedure and during drug administration developed symptoms and electrocardiographic changes suggestive of ST-segment elevation acute coronary syndrome. The drug was suspended and coronary angiography excluded epicardial coronary disease...
December 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
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