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https://www.readbyqxmd.com/read/28538774/influence-of-the-ventilatory-mode-on-acute-adverse-effects-and-facial-thermography-after-noninvasive-ventilation
#1
Suzy Maria Montenegro Pontes, Luiz Henrique de Paula Melo, Nathalia Parente de Sousa Maia, Andrea da Nóbrega Cirino Nogueira, Thiago Brasileiro Vasconcelos, Eanes Delgado Barros Pereira, Vasco Pinheiro Diógenes Bastos, Marcelo Alcantara Holanda
Objective: To compare the incidence and intensity of acute adverse effects and the variation in the temperature of facial skin by thermography after the use of noninvasive ventilation (NIV). Methods: We included 20 healthy volunteers receiving NIV via oronasal mask for 1 h. The volunteers were randomly divided into two groups according to the ventilatory mode: bilevel positive airway pressure (BiPAP) or continuous positive airway pressure (CPAP). Facial thermography was performed in order to determine the temperature of the face where it was in contact with the mask and of the nasal dorsum at various time points...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28536562/use-of-wild-type-or-recombinant-lactic-acid-bacteria-as-an-alternative-treatment-for-gastrointestinal-inflammatory-diseases-a-focus-on-inflammatory-bowel-diseases-and-mucositis
#2
REVIEW
Rodrigo D De Oliveira Carvalho, Fillipe L R do Carmo, Alberto de Oliveira Junior, Philippe Langella, Jean-Marc Chatel, Luis G Bermúdez-Humarán, Vasco Azevedo, Marcela S de Azevedo
The human gastrointestinal tract (GIT) is highly colonized by bacterial communities, which live in a symbiotic relationship with the host in normal conditions. It has been shown that a dysfunctional interaction between the intestinal microbiota and the host immune system, known as dysbiosis, is a very important factor responsible for the development of different inflammatory conditions of the GIT, such as the idiopathic inflammatory bowel diseases (IBD), a complex and multifactorial disorder of the GIT. Dysbiosis has also been implicated in the pathogenesis of other GIT inflammatory diseases such as mucositis usually caused as an adverse effect of chemotherapy...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28527479/-biliary-anastomosis-in-liver-transplantation-with-or-without-t-tube
#3
Janine Carmelino, Susana Rodrigues, Hugo Pinto Marques, Vasco Ribeiro, Daniel Virella, Marta Alves, Américo Martins, Eduardo Barroso
INTRODUCTION: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis. MATERIAL AND METHODS: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis...
February 27, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28517046/three-dimensional-proximal-flow-convergence-automatic-calculation-for-determining-mitral-valve-area-in-rheumatic-mitral-stenosis
#4
Francisco Sampaio, Ricardo Ladeiras-Lopes, João Almeida, Paulo Fonseca, Ricardo Fontes-Carvalho, José Ribeiro, Vasco Gama
PURPOSE: Management of patients with mitral stenosis (MS) depends heavily on the accurate quantification of mitral valve area (MVA) using echocardiography. All currently used two-dimensional (2D) methods have limitations. Estimation of MVA using the proximal isovelocity surface area (PISA) method with real time three-dimensional (3D) echocardiography may circumvent those limitations. We aimed to evaluate the accuracy of 3D direct measurement of PISA in the estimation of MVA. METHODS: Twenty-seven consecutive patients (median age of 63 years; 77...
May 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28516859/recombinant-esterase-from-corynebacterium-pseudotuberculosis-in-dna-and-subunit-recombinant-vaccines-partially-protects-mice-against-challenge
#5
Alexandre Antunes Brum, Andrea de Fatima Silva Rezende, Francisco Silvestre Brilhante, Thais Collares, Karine Begnine, Fabiana Kommling Seixas, Tiago Veiras Collares, Odir Antônio Dellagostin, Vasco Azevedo, Anderson Santos, Ricardo Wagner Portela, Sibele Borsuk
PURPOSE: We tested the efficacy of the esterase encoded by cp1002_RS09720 from Corynebacteriumpseudotuberculosis in recombinant subunit and DNA caseous lymphadenitis (CLA) vaccines. This target was predicted as one of the best CLA vaccine candidates by mature epitope density analysis. METHODOLOGY: Gene cp1002_RS09720 was cloned into two different vectors (pAE for subunit vaccine and pTARGET for DNA vaccine). Four groups of 15 mice each were immunized with the recombinant esterase rCP09720 associated with aluminium hydroxide adjuvant (G1), pTARGET/cp09720 DNA vaccine (G2), a naked pTARGET (G3) or PBS as a negative control (G4)...
May 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28505761/dispersive-transport-and-symmetry-of-the-dispersion-tensor-in-porous-media
#6
Steven R Pride, Donald W Vasco, Eirik G Flekkoy, Ran Holtzman
The macroscopic laws controlling the advection and diffusion of solute at the scale of the porous continuum are derived in a general manner that does not place limitations on the geometry and time evolution of the pore space. Special focus is given to the definition and symmetry of the dispersion tensor that is controlling how a solute plume spreads out. We show that the dispersion tensor is not symmetric and that the asymmetry derives from the advective derivative in the pore-scale advection-diffusion equation...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28504232/portugal-coronary-and-structural-heart-interventions-from-2010-to-2015
#7
Rui Campante Teles, Gustavo Pires-Morais, Pedro Canas da Silva, Rui Cruz Ferreira, Manuel de Sousa Almeida, Filipe Seixo, Marco Costa, Vasco Gama Ribeiro, Jorge Marques, João Carlos Silva, Hélder Pereira, Pedro Farto E Abreu, Henrique Carvalho, Eduardo Infante de Oliveira
The aim of the present paper is to report trends in Portuguese interventional cardiology from 2010 to 2015. We studied data from the prospective multicentre Portuguese National Registry of Interventional Cardiology (RNCI) to analyse percutaneous coronary intervention (PCI) procedures and structural heart interventions from 2010 to 2015. A total of 73,977 PCIs and 780 transcatheter aortic valve implants were performed during the study period. Since 2010 there has been a 60% increase in PCI procedures and a twofold increase in primary angioplasty rates reaching 316 per million population...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504095/characterization-of-porcine-trueperella-pyogenes-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry-maldi-tof-ms-molecular-typing-and-antimicrobial-susceptibility-profiling-in-sao-paulo-state
#8
Luisa Z Moreno, Carlos E C Matajira, Barbara L P da Costa, Thais S P Ferreira, Givago F R Silva, Mauricio C Dutra, Vasco T M Gomes, Ana Paula S Silva, Ana Paula G Christ, Maria Inês Z Sato, Andrea M Moreno
Trueperella pyogenes can be found as a commensal or pathogenic bacterium among animals causing a variety of pyogenic infections in several species. The agent appears to act primarily as an opportunistic pathogen but may disseminate and produce metastatic abscesses accompanied or not by mastitis, metritis or pneumonia. In this study, 30 porcine T. pyogenes strains were identified by MALDI-TOF MS and 16S rRNA sequencing and further evaluated in relation to their resistance and genetic profiles through broth microdilution and single enzyme AFLP...
April 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28499719/diabetes-hypoxia-and-cardiovascular-disease-from-molecular-mechanism-to-treatment
#9
João Vasco Ferreira
No abstract text is available yet for this article.
May 9, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28494371/improving-surface-emg-burst-detection-in-infrahyoid-muscles-during-swallowing-using-digital-filters-and-discrete-wavelet-analysis
#10
Sebastian Restrepo-Agudelo, Sebastian Roldan-Vasco, Lina Ramirez-Arbelaez, Santiago Cadavid-Arboleda, Estefania Perez-Giraldo, Andres Orozco-Duque
The visual inspection is a widely used method for evaluating the surface electromyographic signal (sEMG) during deglutition, a process highly dependent of the examiners expertise. It is desirable to have a less subjective and automated technique to improve the onset detection in swallowing related muscles, which have a low signal-to-noise ratio. In this work, we acquired sEMG measured in infrahyoid muscles with high baseline noise of ten healthy adults during water swallowing tasks. Two methods were applied to find the combination of cutoff frequencies that achieve the most accurate onset detection: discrete wavelet decomposition based method and fixed steps variations of low and high cutoff frequencies of a digital bandpass filter...
May 3, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28490595/sensing-of-hiv-1-entry-triggers-a-type-i-interferon-response-in-human-primary-macrophages
#11
Jérémie Decalf, Marion Desdouits, Vasco Rodrigues, François-Xavier Gobert, Matteo Gentili, Santy Marques-Ladeira, Célia Chamontin, Marylène Mougel, Bruna Cunha de Alencar, Philippe Benaroch
Along with CD4+ T lymphocytes, macrophages are a major cellular source of HIV-1 replication, and a potential viral reservoir. Following entry and reverse transcription in macrophages, cloaking of the viral cDNA by the HIV-1 capsid limits its cytosolic detection, enabling efficient replication. However, whether incoming HIV-1 particles are sensed by macrophages prior to reverse-transcription, remains unclear. Here, we show that HIV-1 triggers a broad expression of interferon-stimulated genes (ISG) in monocyte-derived macrophages within a few hours after infection...
May 10, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28488922/predicting-prognosis-in-patients-with-advanced-cancer-a-prospective-study
#12
Teresa Tavares, Margarida Oliveira, João Gonçalves, Vera Trocado, Jéssica Perpétuo, Alexandra Azevedo, Firmino Machado, Vasco Barreto, Céu Rocha
BACKGROUND: Prognosis is one of the most challenging questions with which physicians are confronted. Accuracy in the prediction of survival is necessary for clinical, ethical, and organizational reasons. AIM: Evaluate young doctors' clinical prediction of survival and the aids they could get: expert opinion, Palliative Prognostic score, and Palliative Prognostic Index. DESIGN: Prospective, observational study. SETTING/PARTICIPANTS: Advanced cancer patients under observation of an inhospital palliative care team, from April to July 2014...
May 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28472265/volumous-multiloculated-tuberculous-pericarditis-in-a-patient-with-human-immunodeficiency-virus-infection
#13
João Gonçalves Almeida, Ana Isabel Azevedo, José Ribeiro, Vasco Gama Ribeiro
No abstract text is available yet for this article.
May 2, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28457948/analysis-of-contextual-variables-in-the-evaluation-of-child-abuse-in-the-pediatric-emergency-setting
#14
Ana Nunes de Almeida, Vasco Ramos, Helena Nunes de Almeida, Carlos Gil Escobar, Catarina Garcia
OBJECTIVE: This article comprises a sample of abuse modalities observed in a pediatric emergency room of a public hospital in the Lisbon metropolitan area and a multifactorial characterization of physical and sexual violence. The objectives are: (1) to discuss the importance of social and family variables in the configuration of both types of violence; (2) to show how physical and sexual violence have subtypes and internal diversity. METHODS: A statistical analysis was carried out in a database (1063 records of child abuse between 2004 and 2013)...
April 27, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28452007/lps-oleuropein-and-blueberry-extracts-affect-the-survival-morphology-and-phosphoinositide-signalling-in-stimulated-human-endothelial-cells
#15
Vincenza Rita Lo Vasco, Martina Leopizzi, Valeria Di Maio, Tania Di Raimo, Stefania Cesa, Alessandra Masci, Carlo Della Rocca
Endothelial cells (EC) act as leading actors in angiogenesis. Understanding the complex network of signal transduction pathways which regulate angiogenesis might offer insights in the regulation of normal and pathological events, including tumours, vascular, inflammatory and immune diseases. The effects of olive oil and of Blueberry extracts upon the phosphoinositide (PI)-specific phospholipase C (PLC) enzymes were evaluated both in quiescent and inflammatory stimulated human umbilical vein EC (HUVEC) using molecular biology (multiliquid bioanalysis) and immunofluorescence techniques...
April 27, 2017: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/28451588/lead-extraction-of-cardiac-rhythm-devices-a-report-of-a-single-center-experience
#16
Ana Isabel Azevedo, João Primo, Helena Gonçalves, Marco Oliveira, Luís Adão, Elisabeth Santos, José Ribeiro, Marlene Fonseca, Adelaide V Dias, Luís Vouga, Vasco Gama Ribeiro
INTRODUCTION AND OBJECTIVES: The rate of implanted cardiac electronic devices is increasing as is the need to manage long-term complications. Lead removal is becoming an effective approach to treat such complications. We present our experience in lead removal using different approaches, analyzing the predictors of the use of mechanical extractors/surgical removal. METHODS: Retrospective analysis of lead extractions in a series of 76 consecutive patients (mean age 70...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28445543/comparative-genomic-analysis-between-corynebacterium-pseudotuberculosis-strains-isolated-from-buffalo
#17
Marcus Vinicius Canário Viana, Henrique Figueiredo, Rommel Ramos, Luis Carlos Guimarães, Felipe Luiz Pereira, Fernanda Alves Dorella, Salah Abdel Karim Selim, Mohammad Salaheldean, Artur Silva, Alice R Wattam, Vasco Azevedo
Corynebacterium pseudotuberculosis is a Gram-positive, pleomorphic, facultative intracellular pathogen that causes Oedematous Skin Disease (OSD) in buffalo. To better understand the pathogenic mechanisms of OSD, we performed a comparative genomic analysis of 11 strains of C. pseudotuberculosis isolated from different buffalo found to be infected in Egypt during an outbreak that occurred in 2008. Sixteen previously described pathogenicity islands (PiCp) were present in all of the new buffalo strains, but one of them, PiCp12, had an insertion that contained both a corynephage and a diphtheria toxin gene, both of which may play a role in the adaptation of C...
2017: PloS One
https://www.readbyqxmd.com/read/28443683/redox-signaling-mediated-by-thioredoxin-and-glutathione-systems-in-the-central-nervous-system
#18
Xiaoyuan Ren, Lili Zou, Xu Zhang, Vasco Branco, Jun Wang, Cristina Carvalho, Arne Holmgren, Jun Lu
SIGNIFICANCE: The thioredoxin (Trx) and glutathione (GSH) systems play important roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress due to its high-energy demand. These two disulfide reductase systems are active in various areas of the brain and are considered to be critical antioxidant systems in the central nervous system (CNS). Various neuronal disorders have been characterized to have imbalanced redox homeostasis. Recent Advances: In addition to their detrimental effects, recent studies have highlighted that reactive oxygen species/reactive nitrogen species (ROS/RNS) act as critical signaling molecules by modifying thiols in proteins...
May 18, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28430911/a-devices-game-of-thrones-cardiac-resynchronization-therapy-vs-pacemaker
#19
Sara Moura-Ferreira, Helena Gonçalves, Marco Oliveira, João Primo, Paulo Fonseca, José Ribeiro, Elisabeth Santos, Nuno Pelicano, Dinis Martins, Vasco Gama
Aims: Oversensing can interfere with biventricular pacing. Cardiac Resynchronization Therapy (CRT) output inhibition due to automatic brady mode change from a sensing to a pacing mode of a previously implanted pacemaker as it reached battery capacity depleted indicator has not been previously published in the medical literature. Methods and Results: We report the first case of CRT output inhibition in a pacemaker dependent patient due to electrical stimuli from a previously right-sided implanted pacemaker, after unaware reversion of OVO mode (O = no chambers paced; V = ventricular sensing; O = no response to sensing) to backup VVI (V = ventricular pacing; V = ventricular sensing; I = inhibitory response to sensing) when it reached the elective replacement interval...
April 18, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28416003/characterization-and-risk-estimate-of-cancer-in-patients-with-primary-sj%C3%A3-gren-syndrome
#20
Pilar Brito-Zerón, Belchin Kostov, Guadalupe Fraile, Daniel Caravia-Durán, Brenda Maure, Francisco-Javier Rascón, Mónica Zamora, Arnau Casanovas, Miguel Lopez-Dupla, Mar Ripoll, Blanca Pinilla, Eva Fonseca, Miriam Akasbi, Gloria de la Red, Miguel-Angel Duarte-Millán, Patricia Fanlo, Pablo Guisado-Vasco, Roberto Pérez-Alvarez, Antonio J Chamorro, César Morcillo, Iratxe Jiménez-Heredia, Isabel Sánchez-Berná, Armando López-Guillermo, Manuel Ramos-Casals
BACKGROUND: The purpose of this study is to characterize the risk of cancer in a large cohort of patients with primary Sjögren syndrome (SjS). METHODS: We had analyzed the development of cancer in 1300 consecutive patients fulfilling the 2002 SjS classification criteria. The baseline clinical and immunological characteristics and systemic activity (ESSDAI scores) were assessed at diagnosis as predictors of cancer using Cox proportional hazards regression analysis adjusted for age at diagnosis and gender...
April 17, 2017: Journal of Hematology & Oncology
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