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https://www.readbyqxmd.com/read/27910626/a-high-resolving-power-x-ray-spectrometer-for-the-omega-ep-laser-invited
#1
P M Nilson, F Ehrne, C Mileham, D Mastrosimone, R K Jungquist, C Taylor, C R Stillman, S T Ivancic, R Boni, J Hassett, D J Lonobile, R W Kidder, M J Shoup, A A Solodov, C Stoeckl, W Theobald, D H Froula, K W Hill, L Gao, M Bitter, P Efthimion, D D Meyerhofer
A high-resolving-power x-ray spectrometer has been developed for the OMEGA EP Laser System based on a spherically bent Si [220] crystal with a radius of curvature of 330 mm and a Spectral Instruments (SI) 800 Series charge-coupled device. The instrument measures time-integrated x-ray emission spectra in the 7.97- to 8.11-keV range, centered on the Cu Kα1 line. To demonstrate the performance of the spectrometer under high-power conditions, Kα1,2 emission spectra were measured from Cu foils irradiated by the OMEGA EP laser with 100-J, 1-ps pulses at focused intensities above 10(18) W/cm(2)...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910348/demonstration-of-imaging-x-ray-thomson-scattering-on-omega-ep
#2
Patrick X Belancourt, Wolfgang Theobald, Paul A Keiter, Tim J B Collins, Mark J Bonino, Pawel M Kozlowski, Sean P Regan, R Paul Drake
Foams are a common material for high-energy-density physics experiments because of low, tunable densities, and being machinable. Simulating these experiments can be difficult because the equation of state is largely unknown for shocked foams. The focus of this experiment was to develop an x-ray scattering platform for measuring the equation of state of shocked foams on OMEGA EP. The foam used in this experiment is resorcinol formaldehyde with an initial density of 0.34 g/cm(3). One long-pulse (10 ns) beam drives a shock into the foam, while the remaining three UV beams with a 2 ns square pulse irradiate a nickel foil to create the x-ray backlighter...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27884931/mild-depressive-symptoms-mediate-the-impact-of-childhood-trauma-on-long-term-functional-outcome-in-early-psychosis-patients
#3
Luis Alameda, Philippe Golay, Philipp S Baumann, Pierre Progin, Nadir Mebdouhi, Julien Elowe, Carina Ferrari, Kim Q Do, Philippe Conus
INTRODUCTION: The mechanism linking childhood trauma (CT) to the functional deficits observed in early psychosis (EP) patients is as yet unknown. We aim to examine the potential mediating effect of depressive symptoms in this well-established association. METHODS: Two hundred nine EP subjects aged 18-35 were assessed for functioning and psychopathology after 2, 6, 12, 18, 24, 30, and 36 months of treatment. Patients were classified into early trauma if they had faced at least one experience of abuse (physical, sexual, or emotional) or neglect (physical or emotional) before age 12, and late trauma if the exposure had occurred between ages 12 and 16...
November 24, 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/27843302/factors-influencing-access-to-education-decision-making-and-receipt-of-preferred-dialysis-modality-in-unplanned-dialysis-start-patients
#4
Anna Machowska, Mark Dominik Alscher, Satyanarayana Reddy Vanga, Michael Koch, Michael Aarup, Abdul Rashid Qureshi, Bengt Lindholm, Peter A Rutherford
OBJECTIVES: Unplanned dialysis start (UPS) leads to worse clinical outcomes than planned start, and only a minority of patients ever receive education on this topic and are able to make a modality choice, particularly for home dialysis. This study aimed to determine the predictive factors for patients receiving education, making a decision, and receiving their preferred modality choice in UPS patients following a UPS educational program (UPS-EP). METHODS: The Offering Patients Therapy Options in Unplanned Start (OPTiONS) study examined the impact of the implementation of a specific UPS-EP, including decision support tools and pathway improvement on dialysis modality choice...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27843054/a-systematic-review-and-meta-analysis-of-randomized-and-nonrandomized-trials-of-clinical-emotional-freedom-techniques-eft-for-the-treatment-of-depression
#5
Jerrod A Nelms, Liana Castel
BACKGROUND: Among a group of therapies collectively known as energy psychology (EP), emotional freedom techniques (EFT) is the most widely practiced. Clinical EFT is an evidence-based practice combining elements of cognitive and exposure therapies with the manual stimulation of acupuncture points (acupoints). Lacking is a recent quantitative meta-analysis that enhances understanding of the variability and clinical significance of outcomes after clinical EFT treatment in reducing depression...
November 2016: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/27817860/-implementation-of-a-nurse-driven-educational-program-improves-management-of-sorafenib-s-toxicities-in-hepatocellular-carcinoma
#6
Angélique Brunot, Amel M'Sadek, Florence Le Roy, Marielle Duval, Samuel Le Sourd, Elodie Ventroux, Laurence Crouzet, Anne Guillygomarc'h, Eveline Boucher, Nadine Lelievre, Brigitte Laguerre, Julien Edeline
BACKGROUND: Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC). Due to its peculiar toxicities, improving patient's tolerance may need close follow-up. Nurses can play a crucial role, by driving a patient education program (EP). We aimed to prove that adding EP to usual care (UC) improves patient's care. METHODS: Since 2011, oncologists referred patients treated by sorafenib to the EP, driven by clinical nurses. It consisted in a visit before first administration, weekly telephone calls and a visit before each oncologist consultation...
November 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27772015/the-narrative-emotion-process-coding-system-2-0-a-multi-methodological-approach-to-identifying-and-assessing-narrative-emotion-process-markers-in-psychotherapy
#7
Lynne E Angus, Tali Boritz, Emily Bryntwick, Naomi Carpenter, Christianne Macaulay, Jasmine Khattra
OBJECTIVE: Recent studies suggest that it is not simply the expression of emotion or emotional arousal in session that is important, but rather it is the reflective processing of emergent, adaptive emotions, arising in the context of personal storytelling and/or Emotion-Focused Therapy (EFT) interventions, that is associated with change. METHOD: To enhance narrative-emotion integration specifically in EFT, Angus and Greenberg originally identified a set of eight clinically derived narrative-emotion integration markers were originally identified for the implementation of process-guiding therapeutic responses...
October 24, 2016: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/27742624/focused-ultrasound-examination-of-the-chest-on-patients-admitted-with-acute-signs-of-respiratory-problems-a-study-protocol-for-a-pragmatic-randomised-controlled-multicentre-trial
#8
M Riishede, C B Laursen, L S Teglbjærg, A T Lassen, G Baatrup
INTRODUCTION: Patients with acute respiratory problems poses a diagnostic challenge because similar symptoms can be caused by various pathological conditions. Focused ultrasound examination (f-US) of the heart and lungs has proven to increase the diagnostic accuracy in these patients. In this protocol of a randomised multicentre trial, we study the effect of f-US of the heart and lungs in patients with respiratory problems performed by emergency physicians (EP) as soon as the patient arrives to the emergency department (ED)...
October 14, 2016: BMJ Open
https://www.readbyqxmd.com/read/27701845/end-of-life-issues-withdrawal-and-withholding-of-life-sustaining-healthcare-in-the-emergency-department-a-comparison-between-emergency-physicians-and-emergency-registrars-a-sub-study
#9
Philip G Richardson, Jaimi Greenslade, Jonathon Isoardi, Michael Davey, Mark Gillett, Alicia Tucker, Sharon Klim, Anne-Maree Kelly, Ibrahim Abdelmahmoud
OBJECTIVE: We investigated and compared the importance of the considerations and discussions when withdrawing and withholding life-sustaining healthcare between emergency physicians (EP) and emergency registrars (ER). METHODS: This was a sub-study of a prospective cross-sectional questionnaire-based case series conducted in six EDs. Primary outcomes were, which of the discussion and considerations, were rated most important by EP and ER in the decision-making process...
December 2016: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/27666912/atrial-tachycardia-ablated-successfully-from-the-aorta
#10
Mahipat Soni, Deepak Bohara, Anup Taksande, Ajay Mahajan, Pratap Nathani, Yash Lokhandwala
We present a case of recurrent highly symptomatic atrial tachycardia. During electrophysiology (EP) study, this was found to arise close to the AV node. To avoid conduction system damage by radiofrequency (RF) ablation, the aortic cusps were mapped. The tachycardia focus was close to the non-coronary cusp and ablated safely and successfully from this site.
December 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27543976/a-library-of-rare-%C3%AE-1-antitrypsin-aat-variant-phenotypes-to-aid-in-the-diagnosis-of-aat-deficiency
#11
Neval Akbas, Graciela Gonzalez, Gregory J Buffone, David G Grenache, Sridevi Devaraj
OBJECTIVES: α1-Antitrypsin (AAT) deficiency is a hereditary disorder due to defective production of the serine protease inhibitor, AAT, which can cause lung and liver diseases. Severity of disease depends particularly on the phenotypic representation of AAT variants in the patient. METHODS: In this study, we present determination of seven common and nine rare variant phenotypes of AAT using pediatric samples collected in Texas Children's Hospital to address the knowledge gap in the identification of rare variants...
September 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27534261/omega-3-fatty-acids-%C3%A1-3-fatty-acids-in-epilepsy-animal-models-and-human-clinical-trials
#12
Christopher M DeGiorgio, Ameer Y Taha
INTRODUCTION: There is growing interest in alternative and nutritional therapies for drug resistant epilepsy. ῳ-3 fatty acids such as fish or krill oil are widely available supplements used to lower triglycerides and enhance cardiovascular health. ῳ-3 fatty acids have been studied extensively in animal models of epilepsy. Yet, evidence from randomized controlled clinical trials in epilepsy is at an early stage. AREAS COVERED: This report focuses on the key ῳ-3 fatty acids DHA and EPA, their incorporation into the lipid bilayer, modulation of ion channels, and mechanisms of action in reducing excitability within the central nervous system...
October 2016: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/27512082/early-and-long-term-outcome-of-infants-born-extremely-preterm
#13
Samantha Johnson, Neil Marlow
There is no question that birth at extremely low gestational ages presents a significant threat to an infant's survival, health and development. Growing evidence suggests that gestational age may be conceptualised as a continuum in which births before 28 weeks of gestation (extremely preterm: EP) represent the severe end of a spectrum of health and developmental adversity. Although comprising just 1%-2% of all births, EP deliveries pose the greatest challenge to neonatal medicine and to health, education and social services for the provision of ongoing support for survivors with additional needs...
August 10, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27487751/cardiac-radiofrequency-ablation-a-clinical-update-for-nurses
#14
Bridget Shoulders, Jillian Mauriello, Tamika Shellman, Corrinne Follett
The field of electrophysiology (EP) has rapidly evolved from a focus on diagnostic procedures to an emphasis on interventions. Many cardiac arrhythmias traditionally treated with antiarrhythmic agents, cardioversion, or cardiac surgery are now routinely cured with cardiac ablation. To optimally manage the care of cardiac ablation patients, it is essential that nurses have an understanding of the EP procedures and related nursing implications. There are extensive evidence-based resources available in the medical literature; however, there are limited publications geared toward nurses caring for cardiac ablation patients...
September 2016: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/27388666/multimodality-imaging-for-guiding-ep%C3%A2-ablation-procedures
#15
REVIEW
Mario Njeim, Benoit Desjardins, Frank Bogun
Recent advances in 3-dimensional electroanatomical mapping have been met by continuous improvements in the field of cardiac imaging and image integration during ablation procedures. Echocardiography, computed tomography, cardiac magnetic resonance, and nuclear imaging provide information about cardiac anatomy and ultrastructure of the heart that may be crucial for a successful ablation procedure. Techniques and value of pre-procedural, intraprocedural, and post-procedural imaging and image integration are discussed in this review article...
July 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27351902/fate-of-carbamazepine-its-metabolites-and-lamotrigine-in-soils-irrigated-with-reclaimed-wastewater-sorption-leaching-and-plant-uptake
#16
Anat Paz, Galit Tadmor, Tomer Malchi, Jens Blotevogel, Thomas Borch, Tamara Polubesova, Benny Chefetz
Irrigation with reclaimed wastewater may result in the ubiquitous presence of pharmaceutical compounds (PCs) and their metabolites in the agroecosystem. In this study, we focused on two highly persistent anticonvulsant drugs, lamotrigine and carbamazepine and two of its metabolites (EP-CBZ and DiOH-CBZ), aiming to elucidate their behavior in agricultural ecosystem using batch and lysimeter experiments. Sorption of the studied compounds by soils was found to be governed mainly by the soil organic matter level...
October 2016: Chemosphere
https://www.readbyqxmd.com/read/27260999/a-genome-wide-screen-for-dendritically-localized-rnas-identifies-genes-required-for-dendrite-morphogenesis
#17
Mala Misra, Hendia Edmund, Darragh Ennis, Marissa A Schlueter, Jessica E Marot, Janet Tambasco, Ida Barlow, Sara Sigurbjornsdottir, Renjith Mathew, Ana Maria Vallés, Waldemar Wojciech, Siegfried Roth, Ilan Davis, Maria Leptin, Elizabeth R Gavis
Localizing messenger RNAs at specific subcellular sites is a conserved mechanism for targeting the synthesis of cytoplasmic proteins to distinct subcellular domains, thereby generating the asymmetric protein distributions necessary for cellular and developmental polarity. However, the full range of transcripts that are asymmetrically distributed in specialized cell types, and the significance of their localization, especially in the nervous system, are not known. We used the EP-MS2 method, which combines EP transposon insertion with the MS2/MCP in vivo fluorescent labeling system, to screen for novel localized transcripts in polarized cells, focusing on the highly branched Drosophila class IV dendritic arborization neurons...
2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/27260349/focused-cardiopulmonary-ultrasound-for-assessment-of-dyspnea-in-a-resource-limited-setting
#18
Sachita P Shah, Sachin P Shah, Reginald Fils-Aime, Walkens Desir, Joanel Joasil, David M Venesy, Krithika Meera Muruganandan
BACKGROUND: The diagnosis and management of acutely dyspneic patients in resource-limited developing world settings poses a particular challenge. Focused cardiopulmonary ultrasound (CPUS) may assist in the emergency diagnosis and management of patients with acute dyspnea by identifying left ventricular systolic dysfunction, pericardial effusion, interstitial pulmonary edema, and pleural effusion. We sought to assess the accuracy of emergency providers performing CPUS after a training intervention in a limited-resource setting; a secondary objective was to assess the ability of CPUS to affect change of clinician diagnostic assessment and acute management in patients presenting with undifferentiated dyspnea...
December 2016: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/27258735/dysplastic-erythroid-precursors-in-the-myelodysplastic-syndromes-and-the-acute-myeloid-leukemias-is-there-biologic-significance-how-should-blasts-be-counted
#19
John M Bennett, Heinz Tuechler, Carlo Aul, Corinna Strupp, Ulrich Germing
The role of bone marrow dysplastic erythroid precursors (EP) in both MDS and AML has been the subject of considerable debate over the past several decades. We have analyzed a large series of adults with MDS and focused on whether any% of EP identified in the bone marrow aspirates of over 1400 patients selected from the Dusseldorf, Germany adult MDS Registry has prognostic relevance. The data was examined for varying% of blasts, the WHO prognostic MDS subtypes and the IPSS-R. We did not identify any adjustment of bone marrow blast percentage by%EP, incuding the 50% rule" developed by the FAB leukemia working group, to have a meaningful impact on outcome, either leukemic risk of progression or overall survival...
August 2016: Leukemia Research
https://www.readbyqxmd.com/read/27235644/detection-of-phenolic-endocrine-disrupting-chemicals-from-maternal-blood-plasma-and-amniotic-fluid-in-indian-population
#20
Sudhanshu Shekhar, Surbhi Sood, Sadiya Showkat, Christy Lite, Anjalakshi Chandrasekhar, Mariappanadar Vairamani, Barathi S, Winkins Santosh
There is a widespread exposure of general population, including pregnant women and developing fetuses, to the endocrine disrupting chemicals (EDCs). These chemicals have been reported to be present in urine, blood serum, breast milk and amniotic fluid. We aimed to investigate the association between the maternal exposure and in utero fetal exposure levels of these chemicals to study their transfer from maternal to fetal unit indicating prenatal exposure. Samples of maternal blood and amniotic fluid were collected as set from 53 pregnant women at full term...
May 25, 2016: General and Comparative Endocrinology
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