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https://www.readbyqxmd.com/read/28433854/comorbidity-age-of-onset-and-suicidality-in-obsessive-compulsive-disorder-ocd-an-international-collaboration
#1
V Brakoulias, V Starcevic, A Belloch, C Brown, Y A Ferrao, L F Fontenelle, C Lochner, D Marazziti, H Matsunaga, E C Miguel, Ycj Reddy, M C do Rosario, R G Shavitt, A Shyam Sundar, D J Stein, A R Torres, K Viswasam
OBJECTIVES: To collate data from multiple obsessive-compulsive disorder (OCD) treatment centers across seven countries and five continents, and to report findings in relation to OCD comorbidity, age of onset of OCD and comorbid disorders, and suicidality, in a large clinical and ethnically diverse sample, with the aim of investigating cultural variation and the utility of the psychiatric diagnostic classification of obsessive-compulsive and related disorders. METHODS: Researchers in the field of OCD were invited to contribute summary statistics on current and lifetime psychiatric comorbidity, age of onset of OCD and comorbid disorders and suicidality in their patients with OCD...
April 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28433678/montreal-accord-on-patient-reported-outcomes-use-series-paper-4-patient-reported-outcomes-pro-can-inform-clinical-decision-making-in-chronic-care
#2
Clifton O Bingham, Vanessa Noonan, Claudine Auger, Debbie Feldman, Sara Ahmed, Susan J Bartlett
BACKGROUND: Providing patient-centered healthcare requires that patient needs, preferences, and valued outcomes are more fully integrated into all decisions. Patient reported outcome measures (PROs) provide unique information from the patient perspective on overall health, symptoms, burden, and treatment response. OBJECTIVE: We sought to describe applications of PROs in clinical settings and considerations for implementation from the perspectives of PRO researchers, clinicians, administrators, policy makers, and patients attending a multidisciplinary meeting...
April 19, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28433672/montreal-accord-on-patient-reported-outcomes-use-series-paper-1-introduction
#3
Susan J Bartlett, Sara Ahmed
BACKGROUND: Patient-centered healthcare, where we design and deliver care to address the needs and preferences of patients, represents an important paradigm shift. Patient reported outcomes (PROs) are critical to capture the patient voice, understand how illness and treatments affect people, and establish how well services and treatments address what matters most to patients. OBJECTIVE: Originally developed for use in research, PROs are now used to monitor individuals and populations, manage care, evaluate services and providers, and inform policy...
April 19, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28433550/evaluation-of-a-telephone-delivered-community-based-collaborative-care-management-program-for-caregivers-of-older-adults-with-dementia
#4
Shahrzad Mavandadi, Laura O Wray, Suzanne DiFilippo, Joel Streim, David Oslin
OBJECTIVES: To evaluate whether a community-based, telephone-delivered, brief patient/caregiver-centered collaborative dementia care management intervention is associated with improved caregiver and care recipient (CR) outcomes. DESIGN: Longitudinal program evaluation of a clinical intervention; assessments at baseline and 3- and 6-month follow-up. SETTING: General community. PARTICIPANTS: Caregivers (N = 440) of older, community-dwelling, low-income CRs prescribed a psychotropic medication by a primary care provider who met criteria for dementia and were enrolled in the SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program for older adults...
March 27, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28433427/do-medial-pivot-kinematics-correlate-with-patient-reported-outcomes-after-total-knee-arthroplasty
#5
Lucian C Warth, Marshall K Ishmael, Evan R Deckard, Mary Ziemba-Davis, R Michael Meneghini
BACKGROUND: Many total knee arthroplasty (TKA) implants are designed to facilitate a medial pivot kinematic pattern. The purpose of this study was to determine whether intraoperative medial pivot kinematic patterns are associated with improved patient outcomes. METHODS: A retrospective review of consecutive primary TKAs was performed. Sensor-embedded tibial trials determined kinematic patterns intraoperatively. The center of rotation (COR) was identified from 0° to 90° and from 0° to terminal flexion, and designated medial-pivot or non-medial pivot based on accepted criteria...
March 18, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28433374/peritoneal-fluid-cytokines-related-to-endometriosis-in-patients-evaluated-for-infertility
#6
Hilde Jørgensen, Abby S Hill, Michael T Beste, Manu P Kumar, Evan Chiswick, Peter Fedorcsak, Keith B Isaacson, Douglas A Lauffenburger, Linda G Griffith, Erik Qvigstad
OBJECTIVE: Our aim was to characterize peritoneal cytokine profiles in patients with infertility, with and without endometriosis, to illuminate potential differences in immune profiles that may reflect mechanistic differences between these two patient populations. DESIGN: Cross-sectional study. SETTING: University hospital and research center. PATIENT(S): Women undergoing laparoscopy for infertility investigation (n = 107)...
April 19, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28433323/is-there-a-clinically-meaningful-difference-in-patient-reported-dyspnea-in-acute-heart-failure-an-analysis-from-urgent-dyspnea
#7
Peter S Pang, Kathleen A Lane, Miguel Tavares, Alan B Storrow, Changyu Shen, W Frank Peacock, Richard Nowak, Alexandre Mebazaa, Said Laribi, Judd E Hollander, Mihai Gheorghiade, Sean P Collins
BACKGROUND: Dyspnea is the most common presenting symptom in patients with acute heart failure (AHF), but is difficult to quantify as a research measure. The URGENT Dyspnea study compared 3 scales: (1) 10 cm VAS, (2) 5-point Likert, and (3) a 7-point Likert (both VAS and 5-point Likert were recorded in the upright and supine positions). However, the minimal clinically important difference (MCID) to patients has not been well established. METHODS: We performed a secondary analysis from URGENT Dyspnea, an observational, multi-center study of AHF patients enrolled within 1 h of first physician assessment in the ED...
April 19, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28433207/correlation-of-frontal-sinus-recess-anatomy-with-ethnicity-gender-and-pathology
#8
Laura K House, Scott P Stringer, Samantha Seals
PURPOSE: Research on frontal sinus cells has been conflicting regarding relationship between frontal sinus cells and frontal sinus disease. There are no published studies regarding gender differences in frontal sinus disease. No comparisons between African Americans and Caucasians and frontal sinus disease have been published. This study attempts to define the above relationships as well as the relationship between number and types of cells and disease. METHODS: A retrospective chart review was performed on sinus CT scans done from 2003 to 2011 at an academic medical center...
April 12, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28432639/measuring-patient-experience-in-dialysis-a-new-paradigm-of-quality-assessment
#9
REVIEW
Connie M Rhee, Steven M Brunelli, Lalita Subramanian, Francesca Tentori
Patients' experience of care (PEC) is as an important dimension in quality of care. As a distinct entity from patient satisfaction and patient health-related quality of life, PEC is defined as patients' perceptions of the range of interactions they have with the health care system, including care from providers, facilities, and health plans. While traditionally PEC may be ascertained via informal assessments, in recent years, especially in the United States, there has been a shift towards standardized surveillance of PEC amongst dialysis patients in order to: (1) set a normative expectation regarding the importance of PEC; (2) standardize the components of patients' experience that are assessed to minimize potential "blind spots"; (3) provide a direct "voice" to the patient in communicating perceptions of their care; (4) facilitate comparisons of quality across facilities; and (5) broaden accountability for PEC to the entire multidisciplinary dialysis care team...
April 21, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28432402/predictors-of-missed-appointments-in-patients-referred-for-congenital-or-pediatric-cardiac-magnetic-resonance
#10
Jimmy C Lu, Ray Lowery, Sunkyung Yu, Maryam Ghadimi Mahani, Prachi P Agarwal, Adam L Dorfman
BACKGROUND: Congenital cardiac magnetic resonance is a limited resource because of scanner and physician availability. Missed appointments decrease scheduling efficiency, have financial implications and represent missed care opportunities. OBJECTIVE: To characterize the rate of missed appointments and identify modifiable predictors. MATERIALS AND METHODS: This single-center retrospective study included all patients with outpatient congenital or pediatric cardiac MR appointments from Jan...
April 21, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28431908/implementation-of-a-person-centered-medical-care-model-in-a-skilled-nursing-facility-a-pilot-evaluation
#11
Kathleen Abrahamson, Jaclyn Myers, Arif Nazir
OBJECTIVES: The objective of this study was to evaluate the feasibility and impact of implementing a person-centered medical care model for post-acute care residents within a skilled nursing facility (SNF). DESIGN: A mixed-method (qualitative and quantitative) pilot evaluation. SETTING: An 89-bed SNF located within a large midwestern city. PARTICIPANTS: Forty SNF post-acute patients admitted to the facility during a 6-month period were enrolled in the pilot evaluation...
April 18, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28431193/evaluation-of-cholesterol-as-a-biomarker-for-suicidality-in-a-veteran-sample
#12
Chuck Reuter, Barbara Caldwell, Heather Basehore
A reduction in total cholesterol may alter the microviscosity of the brain-cell-membrane, reducing serotonin receptor exposure. The resulting imbalance between serotonin and dopamine may lead to an increased risk for suicidality. The objective of this research was to evaluate total cholesterol as a biological marker for suicidality in a sample of US military veterans. The study population consisted of veterans who received care at the Coatesville Veterans Affairs Medical Center (VAMC) and were included in the Suicide Prevention Coordinator's database for having suicidal ideation with evidence of escalating intent, a documented suicide attempt, or committed suicide between 2009 and 2015...
April 21, 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/28430718/trauma-collaborative-care-intervention-effect-on-surgeon-confidence-in-managing-psychosocial-complications-following-orthopaedic-trauma
#13
Stephen Wegener, Eben Carroll, Joshua Gary, Todd McKinley, Robert O'Toole, Debra Sietsema, Renan Castillo, Katherine Frey, Daniel Scharfstein, Yanjie Huang, Susan Collins, Ellen MacKenzie
OBJECTIVES: The impact of the Trauma Collaborative Care (TCC) program on surgeon confidence in managing the psychosocial sequelae of orthopaedic trauma was evaluated as part of a larger prospective, multisite, cluster clinical trial. We compared confidence and perceived resource availability among surgeons practicing in trauma centers that implemented the TCC program with orthopaedic trauma surgeons in similar trauma centers that did not implement the TCC. DESIGN: Prospective cohort design SETTING:: Level 1 Trauma Centers PARTICIPANTS:: Attending surgeons and Fellows...
April 18, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28428971/retinal-research-in-latin-america-how-did-we-get-here
#14
J Fernando Arevalo
Among the numerous contributions by the Pan-American Association of Ophthalmology (PAAO) to the improvement of ophthalmology in Latin America, it has played an invaluable role in the development of the retina and vitreous subspecialty in the region. The quality of the research published in Latin America demonstrates the development of the retina subspecialty at this region and also the worldwide collaboration pioneered by PAAO and the Pan-American Collaborative Retina Study Group (PACORES). We would suggest further academic relationship at the regional as well as international levels as well as funding research institutes to assist retinal researchers in the region since it is generally thought that there is frequently a lack of government funding at all levels, from patient education to support for health teams to tertiary health care centers...
2017: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://www.readbyqxmd.com/read/28428725/tumor-biopsy-and-patient-enrollment-in-clinical-trials-for-advanced-hepatocellular-carcinoma
#15
Lorenza Rimassa, Maria Reig, Giovanni Abbadessa, Markus Peck-Radosavljevic, William Harris, Vittorina Zagonel, Davide Pastorelli, Elena Rota Caremoli, Camillo Porta, Nevena Damjanov, Hitendra Patel, Bruno Daniele, Maria Lamar, Brian Schwartz, Terri Goldberg, Armando Santoro, Jordi Bruix
Tumor biopsies may help to reliably distinguish hepatocellular carcinoma (HCC) from other tumors, mostly cholangiocarcinoma as well as to identify the patient populations who most benefit from target-driven HCC treatments, in order to improve the success rate of experimental therapies. Clarifying tumor biology may also lead to identify biomarkers with prognostic role and/or enabling to predict response or resistance to therapies. Recently, clinical trials have more efficiently included biomarker endpoints and increasingly collected tumor tissue from enrolled patients...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28428167/developing-a-patient-centered-mhealth-app-a-tool-for-adolescents-with-type-1-diabetes-and-their-parents
#16
Bree E Holtz, Katharine M Murray, Denise D Hershey, Julie K Dunneback, Shelia R Cotten, Amanda J Holmstrom, Arpita Vyas, Molly K Kaiser, Michael A Wood
BACKGROUND: Type 1 diabetes (T1D) afflicts approximately 154,000 people under 20 years of age. Three-quarters of adolescents are not achieving glycosylated hemoglobin (HbA1c) targets, which leads to negative health outcomes. Mobile health (mHealth), the use of technology in health, has been used successfully to improve health in many chronic conditions, including diabetes. OBJECTIVE: The purpose of this study was to use patient-centered research methods to inform and improve the design and functionality of our T1D app, MyT1DHero, and to provide insight for others who are designing a health app for adolescents and parents...
April 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28428048/multi-center-machine-learning-in-imaging-psychiatry-a-meta-model-approach
#17
Petr Dluhoš, Daniel Schwarz, Wiepke Cahn, Neeltje van Haren, René Kahn, Filip Španiel, Jiří Horáček, Tomáš Kašpárek, Hugo Schnack
One of the biggest problems in automated diagnosis of psychiatric disorders from medical images is the lack of sufficiently large samples for training. Sample size is especially important in the case of highly heterogeneous disorders such as schizophrenia, where machine learning models built on relatively low numbers of subjects may suffer from poor generalizability. Via multicenter studies and consortium initiatives researchers have tried to solve this problem by combining data sets from multiple sites. The necessary sharing of (raw) data is, however, often hindered by legal and ethical issues...
April 17, 2017: NeuroImage
https://www.readbyqxmd.com/read/28427928/objective-versus-subjective-measures-of-executive-functions-predictors-of-participation-and-quality-of-life-in-parkinson-s-disease
#18
Thialda T Vlagsma, Janneke Koerts, Oliver Tucha, Hilde T Dijkstra, Annelien A Duits, Teus van Laar, Jacoba M Spikman
OBJECTIVE: To determine whether objective (neuropsychological tests) and subjective measures (questionnaires) of executive functions (EF) are associated in patients with Parkinson's disease (PD) and to determine to what extent level of participation and QoL of PD patients can be predicted by these measures of EF. DESIGN: Correlational research design (case-control and prediction design). SETTING: Assessment took place at departments of Neuropsychology of three medical centers in The Netherlands...
April 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28427281/the-servier-oncology-pipeline-in-2017
#19
Patrick Therasse, Beatrice Perron, Sarah A Novack, Jean-Pierre Abastado
Cancer is a complex, multifactorial disease that for years has been the focus of intensive research efforts to explore both the molecular and biological mechanisms involved and the development of novel agents to target these pathways. Servier is an independent French pharmaceutical company with a focus on oncology. Currently, Servier's commercial portfolio includes agents used to treat non-Hodgkin's lymphoma and metastatic colorectal cancer; Servier's oncology pipeline involves agents for the treatment of both solid and hematological tumors...
April 21, 2017: Future Oncology
https://www.readbyqxmd.com/read/28427137/-bibliometric-analysis-of-scientific-articles-on-epidemiological-study-of-burns-in-china
#20
W F Cheng, Z A Shen, D X Zhao, D W Li, Y R Shang
Objective: To analyze the current status of epidemiological study of burns in China, and to explore the related strategies. Methods: Retrospective or cross-sectional scientific articles in Chinese or English on epidemiological study of burns in China published from January 2005 to December 2015 were systemically retrieved from 4 databases. The databases include PubMed, Embase, China Biology Medicine disc, and Chinese Journals Full-text Database. From the results retrieved, data with regard to publication year, journal distribution, number of institutions participated in the study, affiliation of the first author and its location, and admission time span and age of patients in all the scientific articles were collected...
April 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
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