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https://www.readbyqxmd.com/read/28930855/distal-adding-on-phenomenon-in-adolescent-idiopathic-scoliosis-patients-with-thoracolumbar-vertebra-fusion-a-case-control-study
#1
Wei Xu, Chao Chen, Yifan Li, Changwei Yang, Ming Li, Zhikun Li, Xiaodong Zhu
The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding-on phenomenon after posterior correction surgery in AIS patients and compare different treatment strategies to guide the selection of the lowest instrumented vertebra (LIV).All types of Lenke AIS patients who received correction surgery at our center from January 2009 to July 2014 were analyzed...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930061/promoting-adoption-of-medication-for-opioid-and-alcohol-use-disorders-through-system-change
#2
James H Ford, Amanda J Abraham, Nicoleta Lupulescu-Mann, Raina Croff, Kim A Hoffman, Kelly Alanis-Hirsch, Mady Chalk, Laura Schmidt, Dennis McCarty
OBJECTIVE: The Medication Research Partnership (MRP), a collaboration between a national commercial health plan and nine addiction treatment centers, implemented organizational and system changes to promote use of federally approved medications for treatment of alcohol and opioid use disorders. METHOD: A difference-in-differences analysis examined change over time in the percentage of patients receiving a prescription medication for alcohol or opioid use disorders treated in MRP (n = 9) and comparison (n = 15) sites...
September 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28929860/adolescent-perspectives-on-patient-provider-sexual-health-communication-a-qualitative-study
#3
Andrea J Hoopes, Samantha K Benson, Heather B Howard, Diane M Morrison, Linda K Ko, Taraneh Shafii
BACKGROUND: Adolescents in the United States are disproportionately affected by sexually transmitted infections and unintended pregnancy. Adolescent-centered health services may reduce barriers to health care; yet, limited research has focused on adolescents' own perspectives on patient-provider communication during a sexual health visit. METHODS: Twenty-four adolescents (14-19 years old) seeking care in a public health clinic in Washington State participated in one-on-one qualitative interviews...
September 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28929406/pharmacopollution-and-household-waste-medicine-hwm-how-reverse-logistics-is-environmentally-important-to-brazil
#4
André Luiz Pereira, Raphael Tobias de Vasconcelos Barros, Sandra Rosa Pereira
Pharmacopollution is a public health and environmental outcome of some active pharmaceutical ingredients (API) and endocrine-disrupting compounds (EDC) dispersed through water and/or soil. Its most important sources are the pharmaceutical industry, healthcare facilities (e.g., hospitals), livestock, aquaculture, and households (patients' excretion and littering). The last source is the focus of this article. Research questions are "What is the Household Waste Medicine (HWM) phenomenon?", "How HWM and pharmacopollution are related?", and "Why is a reverse logistic system necessary for HWM in Brazil?" This article followed the seven steps proposed by Rother (2007) for a systematic review based on the Cochrane Handbook and the National Health Service (NHS) Center for Reviews Dissemination (CDR) Report...
September 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28928955/pediatric-liver-failure-we-came-we-saw-but-have-we-conquered
#5
REVIEW
Sara Kathryn Smith, Philip Rosenthal
Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible brain injury, in many patients exists. Much of the research surrounding pediatric acute liver failure in the last several years has centered on the development of predictive scoring systems to enhance diagnosis and treatment decisions. In this article, we will discuss our current understanding of liver failure and updated management strategies in children with acute liver failure...
2017: F1000Research
https://www.readbyqxmd.com/read/28928864/high-immunoreactivity-of-duox2-is-associated-with-poor-response-to-preoperative-chemoradiation-therapy-and-worse-prognosis-in-rectal-cancers
#6
Shih-Chun Lin, I-Wei Chang, Pei-Ling Hsieh, Ching-Yih Lin, Ding-Ping Sun, Ming-Jen Sheu, Ching-Chieh Yang, Li-Ching Lin, Hong-Lin He, Yu-Feng Tian
Purpose: Colorectal cancer is the third most common cancer and also the fourth most common cause of cancer mortality worldwide. For rectal cancer, neoadjuvant concurrent chemoradiotherapy (CCRT) followed by radical proctectomy is gold standard treatment for patients with stage II/III rectal cancer. By data mining a documented database of rectal cancer transcriptome (GSE35452) from Gene Expression Omnibus, National Center of Biotechnology Information, we recognized that DUOX2 was the most significantly up-regulated transcript among those related to cytokine and chemokine mediated signaling pathway (GO:0019221)...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28928346/medical-students-perceived-educational-needs-to-prevent-and-treat-childhood-obesity
#7
Natalie K Cooke, Sarah L Ash, L Suzanne Goodell
BACKGROUND: Medical schools are challenged to incorporate more prevention-based education into curricula, offering an opportunity to revisit approaches to nutrition education. The objective of this study was to explore United States (US) medical students' understanding of childhood obesity, specifically barriers to childhood obesity prevention and treatment and students' perceived educational deficits. METHODS: The research team conducted phone interviews with 78 3rd- and 4th-year medical students, representing 25 different medical schools across the US...
May 2017: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/28928316/integrated-brief-tobacco-and-alcohol-cessation-intervention-in-a-primary-health-care-setting-in-karnataka
#8
O T Sabari Sridhar, Pratima Murthy, K V Kishore Kumar
BACKGROUND: Tobacco and alcohol use are important preventable risk factors for noncommunicable diseases and need to be addressed in primary health care. OBJECTIVES: To find the effectiveness of Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST)-based brief intervention for alcohol and tobacco in a primary health-care setting in Karnataka. METHODS: This study was conducted in 2012 where one primary health center (PHC) in Karnataka was an intervention site and other the control site...
September 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28927983/the-digital-divide-in-adoption-and-use-of-mobile-health-technology-among-caregivers-of-pediatric-surgery-patients
#9
Emma C Hamilton, Faiez Saiyed, Charles C Miller, Arturo Eguia, Alexandra C Fonseca, George P Baum, KuoJen Tsao, Mary T Austin
PURPOSE: The purpose of this study was to identify mobile Health (mHealth) technology utilization among caregivers of pediatric surgery patients. METHODS: We provided a modified version of the 2012 mobile health survey from the Pew Research Center to English and Spanish-speaking caregivers of children aged <18years presenting to pediatric surgical outpatient clinics from June to July of 2016. RESULTS: A total of 171 caregivers completed the survey and included 57 (34%) whites, 30 (18%) blacks, 75 (44%) Hispanics, and 6 (4%) other races...
September 1, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28927701/an-epileptologist-s-view-seizure-related-outcomes-after-radiofrequency-ablation-for-mesial-temporal-lobe-epilepsy
#10
REVIEW
Zdeněk Vojtěch, Michaela Stará
In this article, we provide an overview of the reasons for the introduction of less invasive treatment modalities in the management of intractable mesial temporal lobe epilepsy (mTLE). We summarize our published research on stereotactic amygdalohippocampectomy (SAHE) and recalculate our data for the patients' last visit. In our previous work, we found that patients achieved long-term seizure-free outcomes in 70.5%. Re-analysis of results in a subgroup of patient who were diagnosed and followed-up at Epilepsy Center, Na Homolce Hospital, Prague, indicate that these outcomes are durable...
September 12, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28927567/discriminative-ability-of-elixhauser-s-comorbidity-measure-is-superior-to-other-comorbidity-scores-for-inpatient-adverse-outcomes-after-total-hip-arthroplasty
#11
Nathaniel T Ondeck, Daniel D Bohl, Patawut Bovonratwet, Ryan P McLynn, Jonathan J Cui, Jonathan N Grauer
BACKGROUND: Identifying patients at highest risk for a complex perioperative course following total hip arthroplasty (THA) is more important than ever in order to educate patients, optimize outcomes, and to minimize cost and length of stay. There are no known studies comparing the clinically relevant discriminative ability of 3 commonly used comorbidity indices for adverse outcomes following THA: Elixhauser Comorbidity Measure (ECM), the Charlson Comorbidity Index (CCI), and the modified Frailty Index (mFI)...
September 1, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28927393/the-complete-digital-workflow-in-fixed-prosthodontics-a-systematic-review
#12
Tim Joda, Fernando Zarone, Marco Ferrari
BACKGROUND: The continuous development in dental processing ensures new opportunities in the field of fixed prosthodontics in a complete virtual environment without any physical model situations. The aim was to compare fully digitalized workflows to conventional and/or mixed analog-digital workflows for the treatment with tooth-borne or implant-supported fixed reconstructions. METHODS: A PICO strategy was executed using an electronic (MEDLINE, EMBASE, Google Scholar) plus manual search up to 2016-09-16 focusing on RCTs investigating complete digital workflows in fixed prosthodontics with regard to economics or esthetics or patient-centered outcomes with or without follow-up or survival/success rate analysis as well as complication assessment of at least 1 year under function...
September 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28927386/patients-perception-regarding-the-influence-of-individual-and-social-vulnerabilities-on-the-adherence-to-tuberculosis-treatment-a-qualitative-study
#13
Rosiane Davina da Silva, Fernanda Darliane Tavares de Luna, Aguinaldo José de Araújo, Edwirde Luiz Silva Camêlo, Maria Rita Bertolozzi, Paula Hino, Sheylla Nadjane Batista Lacerda, Sayonara Maria Lia Fook, Tânia Maria Ribeiro Monteiro de Figueiredo
BACKGROUND: Tuberculosis remains an important disease which mainly affects the majority of vulnerable individuals in society, who are subjected to poor living conditions and difficulties to access the services of public health. Under these circumstances, the present study aims to understand patients' perception in relation to the influence of individual and social vulnerabilities on the adherence to tuberculosis treatment. METHODS: A qualitative descriptive cross sectional study was conducted in one large municipality at the state of Paraíba, Northeast of Brazil...
September 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28927385/frontline-learning-of-medical-teaching-you-pick-up-as-you-go-through-work-and-practice
#14
W Hartford, L Nimmon, T Stenfors
BACKGROUND: Few medical teachers have received formal teaching education. Along with individual and organizational barriers to participation in teacher training programs, increasing numbers and altered distribution of physicians away from major teaching centers have increased the difficulty of attendance. Furthermore, it is not known if traditional faculty development formats are the optimal learning options given findings from existing studies document both positive and negative outcomes...
September 19, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28926867/diabetes-associated-biobanking-more-topical-than-ever
#15
Katharina Lydia Kynast, Nadine Volk, Thomas Fleming, Esther Herpel
The increasing prevalence of diabetes and its accompanying long-term complications, as well as the associated economic burden, calls for a rapid clinical translation of biomedical research to better valid the physiological relevance of the findings from basic research. To meet this condition, the Collaborative Research Center (CRC) 1118 has established the first nationwide diabetes-specific Biomaterialbank (BMB) that permanently preserves solid and liquid specimen retro- and prospectively at the Institute of Pathology and Department of Endocrinology of the University Hospital Heidelberg...
September 19, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28926299/evidence-based-medicine-in-otolaryngology-part-6-patient-reported-outcomes-in-clinical-practice
#16
Thomas L Carroll, Stella E Lee, Robin Lindsay, Drew Locandro, Gregory W Randolph, Jennifer J Shin
The assessment of patient-reported outcome measures (PROMs) in the outpatient setting is gaining momentum in clinical and research venues. Implementing this data capture into one's practice, however, is not a one-size-fits-all venture, and it is critical to determine when, how, and where to include these patient-centered assessments. This installment of the "Evidence-Based Medicine in Otolaryngology" series provides insight into the implementation process and experiences with successful incorporation of PROMs into clinical practice...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#17
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28925011/trends-in-active-surveillance-for-very-low-risk-prostate-cancer-do-guidelines-influence-modern-practice
#18
Rahul R Parikh, Sinae Kim, Mark N Stein, Bruce G Haffty, Isaac Y Kim, Sharad Goyal
As recommended by current NCCN guidelines, patients with very low-risk prostate cancer may be treated with active surveillance (AS), but this may be underutilized. Using the National Cancer Database (NCDB), we identified men (2010-2013) with biopsy-proven, very low-risk prostate cancer that met AS criteria as suggested by Epstein (stage ≤ T1c; Gleason score (GS) ≤ 6; PSA < 10; and ≤2 [or <33%] positive biopsy cores) and aged ≤76, and low comorbidity index (Charlson-Deyo score = 0). For those patients meeting this criteria, we performed generalized estimation equation (GEE) method with incorporation of correlation in patients clustered within facility to determine the likelihood of undergoing AS...
September 18, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28924425/blood-group-distribution-in-switzerland-a-historical-comparison
#19
Thomas Volken, Rebecca J Crawford, Soraya Amar, Edgar Mosimann, Anita Tschaggelar, Behrouz Mansouri Taleghani
BACKGROUND: Ethnicities differ in prevalence of blood groups and antigens. Substantial donor-recipient mismatch within mixed-ethnic societies may render certain recipients at higher risk for alloimmunization. Data regarding antigen distribution within Switzerland by ethnicity is limited. We examined immigration patterns against the distribution of ABO blood groups using large cross-sectional Swiss samples spanning 70 years. METHODS: Historical ABO blood group distribution data (1940-1945) from Swiss army personnel (n = 275,664) were sourced from the literature...
August 2017: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/28922268/early-exercise-in-critically-ill-youth-and-children-a-preliminary-evaluation-the-weecycle-pilot-trial
#20
Karen Choong, Saif Awladthani, Adeeb Khawaji, Heather Clark, Asm Borhan, Ji Cheng, Sam Laskey, Charmaine Neu, Aimee Sarti, Lehana Thabane, Brian W Timmons, Katina Zheng, Samah Al-Harbi
OBJECTIVES: To determine the feasibility of conducting a full trial evaluating the efficacy of early mobilization using in-bed cycling as an adjunct to physiotherapy, on functional outcomes in critically ill children. DESIGN: Single center, pilot, randomized controlled trial. SETTING: Twelve-bed tertiary care, medical-surgical PICU at McMaster Children's Hospital, Hamilton, ON, Canada. PATIENTS: Children 3-17 years old who were limited to bed-rest with an expected PICU stay of at least 48 hours...
September 15, 2017: Pediatric Critical Care Medicine
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