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https://www.readbyqxmd.com/read/29783691/old-and-young-actors-playing-novel-roles-in-the-drama-of-multiple-myeloma-bone-marrow-microenvironment-dependent-drug-resistance
#1
REVIEW
Sabrina Manni, Marilena Carrino, Gianpietro Semenzato, Francesco Piazza
Multiple myeloma (MM) is the second most frequent hematologic cancer. In addition to the deleterious effects of neoplastic plasma cell growth and spreading during the disease evolution, this tumor is characterized by the serious pathological consequences due to the massive secretion of monoclonal immunoglobulins and by the derangement of bone physiology with progressive weakening of the skeleton. Despite significant progresses having been made in the last two decades in the therapeutic management of this plasma cell tumor, MM remains invariably lethal, due to its extremely complex genetic architecture and to the constant protection it receives from the tumor niche, which is represented by the bone marrow microenvironment...
May 18, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29781526/the-correlation-between-occupational-stress-coping-strategies-and-the-levels-of-psychological-distress-among-nurses-working-in-mental-health-hospital-in-jordan
#2
Abd Alhadi Hasan, Hussein Tumah
PURPOSE: Psychiatric nurses encounter variety of demanding and stressful events such as dealing with aggressive patients, and hostile. This study purposed to assess workplace stress, coping strategies, and psychiatric distress among psychiatric nurses. DESIGN AND METHODS: A descriptive explanatory design was employed. One hundred and nineteen psychiatric nurses were recruited in the study and data were collected in the period between June and September 2017. FINDINGS: The results showed that participants experienced moderate level of occupational stress and psychiatric distress...
May 21, 2018: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/29780891/mind-body-skills-training-for-resident-wellness-a-pilot-study-of-a-brief-mindfulness-intervention
#3
Laura E Romcevich, Suzanne Reed, Stacy R Flowers, Kathi J Kemper, John D Mahan
Background: Interventions to address burnout include mind-body skills training (MBST), but few studies have evaluated the feasibility of MBST for busy pediatric residents. Objective: In this pilot study, we tested the feasibility of a brief MBST intervention, using in-person peer-led training supported by online modules, to decrease stress and burnout in pediatric resident physicians. Methods: Of 99 (10%) residents, 10 residents at Nationwide Children's Hospital in Ohio participated in up to four 90-minute MBST sessions more than 1 month, led by a co-resident with 5 years of informal training in mind-body skills...
January 2018: Journal of Medical Education and Curricular Development
https://www.readbyqxmd.com/read/29776844/psychosocial-predictors-and-psychological-prevention-of-soccer-injuries-a-systematic-review-and-meta-analysis-of-the-literature
#4
REVIEW
Maamer Slimani, Nicola Luigi Bragazzi, Hela Znazen, Armin Paravlic, Fairouz Azaiez, David Tod
OBJECTIVES: To examine (a) the relationships between the psychosocial risk factors and injury rates and (b) the effects of psychological-based prevention interventions on the injury risk of soccer players. DESIGN: Scholarly electronic databases (PubMed/MEDLINE, Google Scholar, Scopus) were searched on 1 January 2017, complemented by manual searches of bibliographies. SETTING: Systematic review and meta-analysis. PARTICIPANTS: We identified 13 eligible studies, including a total of 1149 injured soccer players aged between 14 and 36 years...
May 15, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29770908/level-of-hydrogen-peroxide-affects-expression-and-sub-cellular-localization-of-pax6
#5
Sachin Shukla, Rajnikant Mishra
The Pax6 is a multifunctional pairedbox and homeobox containing transcription factor which is involved in several functions of brain, eyes, and pancreas. It regulates expression of genes involved in cell proliferation, differentiation, inflammation, oxidative stress management, and neuropathy. Dynamic changes in the sub-cellular localization of Pax6 are proposed to regulate its activity, however, the underlying mechanism remains poorly understood. The oxidative stress mediated changes were studied in sub-cellular localization of Pax6 in cultured cells derived from the eye (cornea) and pancreas...
May 16, 2018: Molecular Biology Reports
https://www.readbyqxmd.com/read/29768388/a-rational-emotive-stress-management-intervention-for-reducing-job-burnout-and-dysfunctional-distress-among-special-education-teachers-an-effect-study-erratum
#6
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29765478/neuroelectric-responses-of-sportsmen-and-sedentaries-under-cognitive-stress
#7
Onur Bayazit, Gamze Üngür
Stress and anxiety are states which sportsmen are continuously exposed to. Our study aimed to evaluate neuroelectrical peripheral and central nervous system responses of sportsmen (SPR) and sedentary individuals (SED) during concentration grid test (CGT) employed under time pressure. Forty three SPR and 33 SED participated in the study. Neuroelectrical responses were simultaneously obtained during baseline and CGT. All responses were observed to increase under stress in both SED and SPR. The SPR's stress related peripheral responses were lower than SED's...
June 2018: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29764800/mindfulness-based-symptom-and-stress-management-apps-for-adults-with-chronic-lung-disease-systematic-search-in-app-stores
#8
REVIEW
Otis L Owens, Jenay M Beer, Ligia I Reyes, David G Gallerani, Amanda R Myhren-Bennett, Karen K McDonnell
BACKGROUND: Up to 70% of lung cancer survivors are affected by chronic obstructive pulmonary disease (COPD), a common, debilitating, comorbid disease. Lung cancer and COPD are both characterized by symptoms such as breathlessness, fatigue, and psychological distress. These distressing chronic symptoms are exacerbated by stress and detract from an individual's quality of life. OBJECTIVE: The aim of this study was to identify and evaluate evidence-based, commercially available apps for promoting mindfulness-based strategies among adults with a COPD or lung cancer history (ie, chronic lung disease)...
May 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29762912/professional-and-personal-competency-development-in-near-peer-tutors-of-gross-anatomy-a-longitudinal-mixed-methods-study
#9
Simone Alvarez, Jobst-Hendrik Schultz
There are many benefits to peer and near-peer tutoring. The current literature suggests that near-peer teaching within the domain of gross anatomy may lead to the development of numerous competencies for burgeoning medical professionals. The aim of this study was a quantitative and qualitative approach to explore which professional and personal competencies anatomy tutors developed as a result of their teaching activities in a gross anatomy course at a medical school in Germany. For a period of 18 months, 24 peer tutors were followed and queried multiple times via questionnaire and semi-structured interviews...
May 15, 2018: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29762862/stress-and-the-psyche-brain-immune-network-in-psychiatric-diseases-based-on-psychoneuroendocrineimmunology-a-concise-review
#10
REVIEW
Anna Giulia Bottaccioli, Francesco Bottaccioli, Andrea Minelli
In the last decades, psychoneuroendocrineimmunology research has made relevant contributions to the fields of neuroscience, psychobiology, epigenetics, molecular biology, and clinical research by studying the effect of stress on human health and highlighting the close interrelations between psyche, brain, and bodily systems. It is now well recognized that chronic stress can alter the physiological cross-talk between brain and biological systems, leading to long-lasting maladaptive effects (allostatic overload) on the nervous, immune, endocrine, and metabolic systems, which compromises stress resiliency and health...
May 15, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29760788/the-effectiveness-of-stress-management-training-on-blood-glucose-control-in-patients-with-type-2-diabetes
#11
Fereshteh Zamani-Alavijeh, Marzieh Araban, Hamid Reza Koohestani, Mahmood Karimy
Background: Type 2 diabetes is a chronic disease that is expanding at an alarming rate in the world. Research on individuals with type 2 diabetes showed that stressful life events cause problems in the effective management and control of diabetes. This study aimed at investigating the effect of a stress management intervention on blood glucose control in individuals with type 2 diabetes referred to Zarandeh clinic, Iran. Methods: In this experimental study, 230 individuals with type 2 diabetes (179 female and 51 male) were enrolled and assigned to experimental (n = 115) and control (n = 115) groups...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29758117/associations-among-nursing-work-environment-and-health-promoting-behaviors-of-nurses-and-nursing-performance-quality-a-multilevel-modeling-approach
#12
Hyeonmi Cho, Kihye Han
PURPOSE: This study aimed to determine the relationships among the unit-level nursing work environment and individual-level health-promoting behaviors of hospital nurses in South Korea and their perceived nursing performance quality. METHODS: This study used a cross-sectional design. Data were collected using self-reported questionnaires from 432 nurses in 57 units at five hospitals in South Korea. Nursing performance quality, nursing work environment, and health-promoting behaviors were measured using the Six Dimension Scale of Nursing Performance, Practice Environment Scale of the Nursing Work Index, and Health Promoting Lifestyle Profile-II, respectively...
May 14, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29752045/stressors-of-school-age-children-with-allergic-diseases-a-qualitative-study
#13
Misa Iio, Mana Hamaguchi, Mayumi Nagata, Koichi Yoshida
PURPOSE: Most studies of stress in children with chronic diseases have been geared toward parents and caregivers have not considered allergic diseases together. This study aimed to identify the stressors associated with allergic diseases in Japanese school-age children. DESIGN AND METHODS: Stressors associated with allergic diseases of 11 school-age children (seven boys and four girls; age range: 9-12 years) were investigated using semi-structured interviews. RESULTS: In the qualitative thematic analysis of stressors about allergic diseases, two themes: allergic disease-specific stressors and common stressors in chronic diseases, and 12 categories were identified...
May 8, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29743152/managing-and-controlling-stress-using-mhealth-systematic-search-in-app-stores
#14
David Blázquez Martín, Isabel De La Torre, Begonya Garcia-Zapirain, Miguel Lopez-Coronado, Joel Rodrigues
BACKGROUND: Traditional stress management techniques have been proven insufficient to tackle the needs of today's population. Computational-based techniques and now mobile health (mHealth) apps are showing promise to enable ease of use and access while educating end users on self-management. OBJECTIVE: The main aim of this paper was to put forward a systematic review of mHealth apps for stress management. METHODS: The scenario chosen for this study consists of a sample of the most relevant mHealth apps found on the British and Spanish online stores of the two main mobile operating systems: iOS and Android...
May 9, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29734256/assessing-information-needs-regarding-metabolic-syndrome-among-gynecological-cancer-survivors-a-concurrent-mixed-method
#15
Insil Jang, Ji-Su Kim, Minhae Kim, Eunkyung Lee
BACKGROUND: Cancer survivors have an increased risk of non-cancer-related deaths, particularly metabolic syndrome (MetS). OBJECTIVE: We aimed to assess knowledge deficits regarding metabolism-related diseases among gynecological cancer survivors and the preferred source of health information. METHODS: Using a mixed methods approach, 70 participants responded to a structured modified version of the MetS questionnaire. We conducted 28 semistructured interviews of gynecological cancer survivors with MetS...
April 27, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29729012/stress-and-psoriasis
#16
REVIEW
Laurie Rousset, Bruno Halioua
The links between psoriasis and stress are complex. This article proposes a review of the literature on the relationship between stress and psoriasis. In 31-88% of cases, patients report stress as being a trigger for their psoriasis. There was also a reported higher incidence of psoriasis in subjects who had a stressful event the previous year, suggesting that stress may have a role in triggering the disease in predisposed individuals. Stress is also a consequence of psoriasis outbreaks. Understanding the role of stress makes it appropriate to target stress when proposing treatment to patients with psoriasis...
May 4, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29723026/crisis-counselor-perceptions-of-job-training-stress-and-satisfaction-during-disaster-recovery
#17
Nikki D Bellamy, Min Qi Wang, Lori A McGee, Julie S Liu, Maryann E Robinson
OBJECTIVE: The United States Crisis Counseling Assistance and Training Program (CCP; authorized by the Robert T. Stafford Disaster Relief and Emergency Assistance Act, 1974/2013) aims to provide disaster-recovery support to communities following natural or human-caused disasters through outreach. Job satisfaction among the crisis counselors the CCP employs may affect the delivery of outreach services to survivors and their communities. The present study was conducted to gain insight into CCP crisis counselors' experiences with job training and work-related stress as predictors of job satisfaction...
May 3, 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29717647/a-three-step-model-of-stress-management-for-health-leaders
#18
Elizabeth Hartney
The current healthcare system is often as highly stressful environment for patients, their families, and for the employees of the system. Health leaders also experience stress, which can have profound repercussions if not well managed. This article describes the impact of stress on the brain and nervous system functioning of health leaders, then, drawing on evidence from the literature, presents a three-step model for managing stress at the individual, team/organizational, and system levels.
May 2018: Healthcare Management Forum
https://www.readbyqxmd.com/read/29716605/integration-of-the-work-related-online-aftercare-intervention-gsa-online-plus-healthy-and-without-stress-at-the-workplace-into-clinical-practice-study-protocol-for-an-implementation-study
#19
Rüdiger Zwerenz, Katja Böhme, Astrid Wirth, Nicole Labitzke, Sergei Pachtchenko, Manfred E Beutel
BACKGROUND: In a previous RCT we established the efficacy of the psychodynamic online aftercare programme 'GSA-Online' ('Health Training Stress Management at the Workplace') for rehabilitants with work-related stress facing return to work after long-term sickness absence. The purpose of this trial is to implement it into routine care. METHODS/DESIGN: The study is performed in rehabilitation clinics with patients of different medical indications (psychosomatic, orthopedic and cardiological diseases)...
May 2, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29705846/breaking-away-the-role-of-homeostatic-drive-in-perpetuating-depression
#20
J Tory Toole, Mark A Rice, Travis J A Craddock, Barry Nierenberg, Nancy G Klimas, Mary Ann Fletcher, Joel Zysman, Mariana Morris, Gordon Broderick
We propose that the complexity of regulatory interactions modulating brain neurochemistry and behavior is such that multiple stable responses may be supported, and that some of these alternate regulatory programs may play a role in perpetuating persistent psychological dysfunction. To explore this, we constructed a model network representing major neurotransmission and behavioral mechanisms reported in literature as discrete logic circuits. Connectivity and information flow through this biobehavioral circuitry supported two distinct and stable regulatory programs...
2018: Methods in Molecular Biology
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