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JOURNAL ARTICLE
[Autologous peripheral blood hematopoietic cell transplantation in the treatment of AL-amyloidosis].
A G Smirnova, A V Smirnov, A Zander, B V Afanas'ev
AIM: To evaluate the efficiency of chemotherapy with standard doses of melfalan and dexamethazone versus autologous peripheral hemopoietic cell transplantation (auto-PHCT) in patients with AL amyloidosis and to reveal poor prognostic factors. SUBJECTS AND METHODS: Of 36 patients diagnosed as having AL-amylodosis, 17 patients underwent auto-PHCT, 11 patients received chemotherapy only; 8 patients died prior to treatment. RESULTS: In patients with AL-amyloidosis after chemotherapy and autotransplantation, 3-year overall survival was 28 and 64%, respectively...
2010: Terapevticheskiĭ Arkhiv
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