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https://www.readbyqxmd.com/read/28922262/sugar-in-infants-children-and-adolescents-a-position-paper-of-the-european-society-for-paediatric-gastroenterology-hepatology-and-nutrition-committee-on-nutrition
#1
Nataša Fidler Mis, Christian Braegger, Jiri Bronsky, Cristina Campoy, Magnus Domellöf, Nicholas D Embleton, Iva Hojsak, Jessie Hulst, Flavia Indrio, Alexandre Lapillonne, Walter Mihatsch, Christian Molgaard, Rakesh Vora, Mary Fewtrell
The consumption of sugars, particularly sugar-sweetened beverages (SSBs; beverages or drinks that contain added caloric sweeteners (i.e. sucrose, high-fructose corn syrup, fruit-juice concentrates), in European children and adolescents exceeds current recommendations. This is of concern because there is no nutritional requirement for free sugars, and infants have an innate preference for sweet taste, which may be modified and reinforced by pre- and postnatal exposures. Sugar containing beverages/free sugars increase the risk for overweight/obesity and dental caries, can result in poor nutrient supply and reduced dietary diversity and may be associated with increased risk of type 2 diabetes mellitus, cardiovascular risk, and other health effects...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28921988/interaction-of-food-additives-with-intestinal-efflux-transporters
#2
Noora Sjöstedt, Feng Deng, Oskari Rauvala, Tuomas Tepponen, Heidi Kidron
Breast cancer resistance protein (BCRP), multidrug resistance associated protein 2 (MRP2) and P-glycoprotein (P-gp) are ABC transporters that are expressed in the intestine, where they are involved in the efflux of many drugs from enterocytes back into the intestinal lumen. The inhibition of BCRP, MRP2 and P-gp can result in the enhanced absorption and exposure of substrate drugs. Food additives are widely used by the food industry to improve the stability, flavor and consistency of food products. Although they are considered safe for consumption, their interactions with intestinal transporters are poorly characterized...
September 18, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28919036/blends-of-non-caloric-sweeteners-saccharin-and-cyclamate-show-reduced-off-taste-due-to-tas2r-bitter-receptor-inhibition
#3
Maik Behrens, Kristina Blank, Wolfgang Meyerhof
Non-caloric sweeteners are widely used for the formulation of calorie-reduced beverages for health-conscious consumers. However, disadvantages such as undesired off-tastes limit the use of non-nutritive sweeteners. Therefore, the food industry is constantly searching for novel sweeteners and frequently resorts to using blends combining non-caloric sweeteners in a single formulation. The earliest blend allowing higher sweetness levels with reduced bitter off-taste combined saccharin with cyclamate. However, the mechanism by which sweetener blends become superior to single compounds remained obscure...
August 23, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28916568/perspective-the-paradox-in-dietary-advanced-glycation-end-products-research-the-source-of-the-serum-and-urinary-advanced-glycation-end-products-is-the-intestines-not-the-food
#4
Luanne R DeChristopher
Inconsistent research results have impeded our understanding of the degree to which dietary advanced glycation end products (dAGEs) contribute to chronic disease. Early research suggested that Western-style fast foods, including grilled and broiled meats and French fries, contain high levels of proinflammatory advanced glycation end products (AGEs). However, recent studies with state-of-the-art ultraperformance LC-tandem mass spectrometry (UPLC-MS) found that there is no evidence that these foods have elevated levels of dAGEs relative to other foods...
September 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28915844/financial-incentives-and-purchase-restrictions-in-a-food-benefit-program-affect-the-types-of-foods-and-beverages-purchased-results-from-a-randomized-trial
#5
Simone A French, Sarah A Rydell, Nathan R Mitchell, J Michael Oakes, Brian Elbel, Lisa Harnack
BACKGROUND: This research evaluated the effects of financial incentives and purchase restrictions on food purchasing in a food benefit program for low income people. METHODS: Participants (n=279) were randomized to groups: 1) Incentive- 30% financial incentive for fruits and vegetables purchased with food benefits; 2) Restriction- no purchase of sugar-sweetened beverages, sweet baked goods, or candies with food benefits; 3) Incentive plus Restriction; or 4) Control- no incentive or restrictions...
September 16, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28912088/sip-and-spit-or-sip-and-swallow-choice-of-methods-differentially-alters-taste-intensity-estimates-across-stimuli
#6
Cordelia A Running, John E Hayes
While the myth of the tongue map has been consistently and repeatedly debunked in controlled studies, evidence for regional differences in suprathreshold intensity has been noted by multiple research groups. Given differences in physiology between the anterior and posterior tongue (fungiform versus foliate and circumvallate papillae) and differences in total area stimulated (anterior only versus whole tongue, pharynx, and epiglottis), small methodological changes (sip and spit versus sip and swallow) have the potential to substantially influence data...
September 11, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28905094/recent-advances-on-the-difructose-anhydride-iv-preparation-from-levan-conversion
#7
REVIEW
Hua Hang
Difructose anhydride IV (DFA IV) is a cyclic disaccharide consisting of two fructose residues, which is obtained from levan conversion with levan fructotransferase (LFTase) and rarely found in nature as a low-calorie sugar substitute. Some beneficial effects of DFA IV connected with its consumption have been described. The article reviews the properties and physiological functions of DFA IV, levan conversion, resources and properties of LFTase and the produced methods of DFA IV. LFTase as a relatively novel enzyme and its molecular evolution are discussed as well...
September 13, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28903608/influence-of-substrates-on-the-in-vitro-kinetics-of-steviol-glucuronidation-and-interaction-between-steviol-glycosides-metabolites-and-ugt2b7
#8
Jun-Ming Chen, Yong-Mei Xia, Yan-Dong Zhang, Tong-Tong Zhang, Qing-Rui Peng, Yun Fang
Steviol glycosides, a natural sweetener, may perform bioactivities via steviol, their main metabolite in human digestion. The metabolising kinetics, i.e. glucuronidation kinetics and interaction between steviol glycosides or their metabolites and metabolising enzyme, are important for understanding the bioactivity and cytotoxicity. The present study investigated kinetics of steviol glucuronidation in human liver microsome and a recombinant human UDP-glucuronosyltransferases isomer, UGT2B7, along with molecular docking to analyse interaction between UGT2B7 and steviol or glucose...
September 13, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28903062/inflammatory-dietary-patterns-and-depressive-symptoms-in-italian-older-adults
#9
Esther Vermeulen, Ingeborg A Brouwer, Karien Stronks, Stefania Bandinelli, Luigi Ferrucci, Marjolein Visser, Mary Nicolaou
BACKGROUND: Older adults are more susceptible to higher inflammatory levels and depression. Moreover, diet may influence inflammation as well as depression but no previous study examined whether inflammatory dietary patterns are related to depression in an older population. To investigate the longitudinal association between inflammatory dietary patterns (using reduced rank regression (RRR)) and depressive symptoms in a population sample of Italian older adults. METHODS: We included 827 participants (aged≥65years) at baseline in 1998...
September 10, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28900868/stability-of-organoleptic-agents-in-pharmaceuticals-and-cosmetics
#10
REVIEW
Akash Patil, Supriya Bhide, Mustafa Bookwala, Bhavik Soneta, Vijaykumar Shankar, Ahmed Almotairy, Mashan Almutairi, S Narasimha Murthy
Organoleptic agents constitute an important niche in the field of pharmaceutical excipients. These agents encompass a range of additives responsible for coloring, flavoring, sweetening, and texturing formulations. All these agents have come to play a significant role in pharmaceuticals and cosmetics due to their ability to increase patient compliance by elevating a formulation's elegance and esthetics. However, it is essential to review their physical and chemical attributes before use, as organoleptic agents, similar to active pharmaceutical ingredients (APIs), are susceptible to physical and chemical instability leading to degradation...
September 12, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28899680/the-cephalic-phase-insulin-response-to-nutritive-and-low-calorie-sweeteners-in-solid-and-beverage-form
#11
Jaapna Dhillon, Janice Y Lee, Richard D Mattes
The purpose of the study was to examine the role of the cephalic phase insulin response (CPIR) following exposure to nutritive and low-calorie sweeteners in solid and beverage form in overweight and obese adults. In addition, the role of learning on the CPIR to nutritive and low-calorie sweetener exposure was tested. Sixty-four overweight and obese adults (age: 18-50years, BMI: 24-37kg/m(2), body fat percentage>25% for men and >32% for women) were sham-fed (at 2-minute intervals for 14min) a randomly assigned test load comprised of a nutritive (sucrose) or low calorie sweetener (sucralose) in beverage or solid form in phase 1 of the study...
September 9, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28899489/enhanced-production-of-xylitol-from-xylose-by-expression-of-bacillus-subtilis-arabinose-h-symporter-and-scheffersomyces-stipitis-xylose-reductase-in-recombinant-saccharomyces-cerevisiae
#12
Hyoju Kim, Hyun-Soo Lee, Haeseong Park, Dae-Hee Lee, Eckhard Boles, Donghwa Chung, Yong-Cheol Park
Inefficient transport of xylose into Saccharomyces cerevisiae is a major hurdle for production of xylitol, a natural sweetener with five carbons. To facilitate the xylose transport and hence increase xylose conversion to xylitol, the araE gene encoding an arabinose:H(+) symporter (AraE) from Bacillus subtilis and the XYL1 gene from Scheffersomyces stipitis were expressed in Saccharomyces cerevisiae EBY.VW4000, a hxt null mutant. The resulting strain of EXHA exhibited 4.1 fold increases in xylose consumption rate and xylitol productivity, relative to the control strain without AraE...
December 2017: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/28899334/the-obesity-epidemic-and-sugar-sweetened-beverages-a-taxing-time
#13
Becky Freeman, Kieron Rooney, Eloise Howse
No abstract text is available yet for this article.
September 18, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28895669/glycemic-load-and-carbohydrates-content-in-the-diets-of-cancer-patients
#14
Anna Czekajło, Dorota Różańska, Anna Mandecka, Klaudia Konikowska, Malwina Madalińska, Andrzej Szuba, Bożena Regulska-Ilow
Background: Glycemic load (GL) is used to evaluate how various food products affect blood sugar level. According to some studies, high dietary GL may increase the risk of cancer development and recurrence. Objective: The aim of the study was to assess dietary glycemic load and intake of carbohydrates derived from various food products by patients staying on an oncological ward. Material and methods: The study group included 100 cancer patients aged 19-83 years (59...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28894468/a-case-of-immediate-hypersensitivity-reaction-to-maltitol
#15
Ana Rodríguez Trabado, Carmen Cámara Hijón, José Antonio García-Trujillo, Irene Magriz Trascón, Luis Miguel Fernández Pereira
BACKGROUND: Maltitol is a sugar alcohol that is frequently used as a noncaloric sweetener, although it is also used as an excipient, a plasticizer in gelatin capsules, and an emollient. It has not been previously described as an agent involved in immediate hypersensitivity reactions. METHODS: We report on an anaphylactoid reaction with pharyngeal occlusion suffered by a 60-year-old man after ingestion of a candy containing maltitol syrup. A prick-to-prick test was performed with the candy and maltitol powder...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28893046/the-association-between-cariogenic-factors-and-the-occurrence-of-early-childhood-caries-in-children-from-salem-district-of-india
#16
Arokiaraj Stephen, Ramesh Krishnan, Paul Chalakkal
INTRODUCTION: Various aetiological factors for Early Childhood Caries (ECC) have been suggested in literature, but the role of each factor has been disputed in various studies. AIM: To evaluate the association between ECC and its related factors in children between three to six years of age, from rural, semi-urban and urban schools in the district of Salem (India). MATERIALS AND METHODS: The study consisted of children between three to six years of age, selected randomly from schools in semi-urban, urban and rural schools at Salem...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28890354/employment-changes-associated-with-the-introduction-of-taxes-on-sugar-sweetened-beverages-and-nonessential-energy-dense-food-in-mexico
#17
Carlos M Guerrero-López, Mariana Molina, M Arantxa Colchero
We assessed changes in employment in the manufacturing industry, the commercial sector and national unemployment rates, associated with the fiscal policies implemented in 2014 in Mexico: a 1 peso per liter excise tax to sugar-sweetened beverages (SSB) and an 8% tax on nonessential energy-dense food. We used data from three nationally representative surveys. Controlling for contextual variables, we used interrupted time series analyses to model changes in number of employees in the SSB and nonessential energy-dense food industry, in commercial establishments selling beverages and food and changes in national unemployment rates...
September 7, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28889856/foods-and-beverages-available-at-snap-authorized-drugstores-in-sections%C3%A2-of%C3%A2-north%C3%A2-carolina
#18
Elizabeth F Racine, Ashley Kennedy, Ameena Batada, Mary Story
OBJECTIVE: To assess healthy food availability in Supplemental Nutrition Assistance Program-authorized drugstores by store chain and neighborhood income level in 3 regions of North Carolina. DESIGN: Cross-sectional, descriptive study. SETTING: Twenty-five counties in North Carolina. PARTICIPANTS: A total of 108 drugstores (36 CVS Health, 36 Rite Aid, and 36 Walgreens). MAIN OUTCOME MEASURE(S): Fifty foods and beverages offered at drugstores, categorized as healthier and less healthy...
September 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28888091/body-weight-misperception-and-health-related-factors-among-iranian-children-and-adolescents-the-caspian-v-study
#19
Pooneh Angoorani, Ramin Heshmat, Hanieh-Sadat Ejtahed, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Hasan Ziaodini, Majzoubeh Taheri, Gita Shafiee, Zeinab Ahadi, Tahereh Aminaee, Roya Kelishadi
BACKGROUND: Along with increased prevalence of obesity, body weight misperception has also increased among adolescents. This study aims to evaluate the proportion of weight misperception among Iranian children and adolescents and its association with some health-related factors. METHODS: Data were collected from 14,440 Iranian students, aged 7-18 years, who participated in the national school-based surveillance program (CASPIAN-V). The students' anthropometric indices and blood pressure were measured using standardized methods, and valid questionnaires were used to assess their weight perception, eating patterns, physical activity and sedentary behaviors...
September 9, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28887089/steviol-an-aglycone-of-steviol-glycoside-sweeteners-interacts-with-the-pregnane-x-pxr-and-aryl-hydrocarbon-ahr-receptors-in-detoxification-regulation
#20
Jan Dusek, Alejandro Carazo, Frantisek Trejtnar, Lucie Hyrsova, Ondřej Holas, Tomas Smutny, Stanislav Micuda, Petr Pavek
Stevia rebaudiana Bertoni is a herb known for the high content of natural sweeteners in its leaves. Its main secondary metabolite stevioside is used as non-caloric sweetener. No information, however, is available on whether stevioside or steviol interact with drug-metabolizing enzymes and pose the potential risk of food-drug interactions. Similarly, data are lacking on the interactions of steviol and stevioside with key nuclear receptors controlling the expression of the main drug metabolizing enzymes. We studied the interactions of steviol and stevioside with the pregnane X (PXR), vitamin D (VDR), constitutive androstane (CAR), farnesoid X (FXR), glucocorticoid (GR) and aryl hydrocarbon (AHR) receptors, which control expression of genes of xenobiotic metabolism...
September 5, 2017: Food and Chemical Toxicology
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