keyword
MENU ▼
Read by QxMD icon Read
search

western diet

keyword
https://www.readbyqxmd.com/read/29226589/hydrochlorothiazide-and-acute-urinary-acidification-the-voltage-hypothesis-of-enac-dependent-h-secretion-refuted
#1
Niklas Ayasse, Pauline I A de Bruijn, Peder Berg, Mads V Sørensen, Jens Leipziger
AIM: The 'voltage hypothesis' of H+ secretion states that urinary acidification following increased Na+ delivery to the collecting duct (CD) is ENaC-dependent leading to transepithelial voltage-dependent increase in H+ secretion. We recently showed that furosemide acidifies the urine independently of ENaC activity. If the voltage hypothesis holds, hydrochlorothiazide (HCT) must acidify the urine. We here tested the acute effect of HCT on urine pH under normal and high ENaC expression...
December 11, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/29225208/dietary-calcium-and-serum-25ohd-protect-chinese-women-from-type-2-diabetes
#2
Lijun Feng, Zhefang Hu, Qingqing Wang
The Chinese dietary structure is different from Western and Mediterranean diets. This study aimed to assess the association of dietary calcium, serum 25-hydroxyvitamin D (25OHD), and other macronutrients with type 2 diabetes (T2D) in Chinese patients. This case-control study enrolled 605 patients (males, 337; females, 268) with T2D and 724 healthy subjects (males, 405; females, 319) at Sir Run Run Shaw Hospital from February to April 2014. Dietary calcium, total energy, fat to energy ratio, glucose administration, 2-h postprandial blood glucose, serum total cholesterol and high density lipoprotein (HDL)-cholesterol, and serum 25OHD level were assessed...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29224910/regulation-of-sirt3-foxo1-signaling-pathway-in-rats-with-non-alcoholic-steatohepatitis-by-salvianolic-acid-b
#3
Yingchun Wang, Juan Chen, Weizong Kong, Ruiping Zhu, Kai Liang, Quanxiang Kan, Yanhong Lou, Xiangyu Liu
AIMS: To explore the effect of salvianolic acid B (Sal B) on regulation of SIRT3/FOXO1 signaling pathway in rats with non-alcoholic steatohepatitis (NASH). METHODS: Sixty Sprague Dawley (SD) rats were randomly divided into control, model and treatment groups. After 12 weeks of successful model establishment with high fat diet, treatment group was given Sal B by intragastric administration. After 12 weeks of treatment, rats were sacrificed and livers were taken to test indicators such as liver index, TG, TC, ALT, AST, reactive oxygen species (ROS) by DCFH-DA probe, SOD2 activity by WST-8 test...
December 7, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29224110/sex-differences-in-androgen-regulation-of-metabolism-in-nonhuman-primates
#4
Cadence True, David H Abbott, Charles T Roberts, Oleg Varlamov
The in-depth characterization of sex differences relevant to human physiology requires the judicious use of a variety of animal models and human clinical data. Nonhuman primates (NHPs) represent an important experimental system that bridges rodent studies and clinical investigations. NHP studies have been especially useful in understanding the role of sex hormones in development and metabolism and also allow the elucidation of the effects of pertinent dietary influences on physiology pertinent to disease states such as obesity and diabetes...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29223827/colonic-aberrant-crypt-formation-accompanies-an-increase-of-opportunistic-pathogenic-bacteria-in-c57bl-6-mice-fed-a-high-fat-diet
#5
Huawei Zeng, Suzanne L Ishaq, Zhenhua Liu, Michael R Bukowski
The increasing worldwide incidence of colon cancer has been linked to obesity and consumption of a high-fat Western diet. To test the hypothesis that a high-fat diet (HFD) promotes colonic aberrant crypt (AC) formation in a manner associated with gut bacterial dysbiosis, we examined the susceptibility to azoxymethane (AOM)-induced colonic AC and microbiome composition in C57/BL6 mice fed a modified AIN93G diet (AIN, 16% fat, energy) or an HFD (45% fat, energy) for 14 weeks. Mice receiving the HFD exhibited increased plasma leptin, body weight, body fat composition and inflammatory cell infiltration in the ileum compared with those in the AIN group...
November 10, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29223809/cadmium-induces-bnip3-dependent-autophagy-in-chicken-spleen-by-modulating-mir-33-ampk-axis
#6
Menghao Chen, Xiaojing Li, Ruifeng Fan, Jie Yang, Xi Jin, Sattar Hamid, Shiwen Xu
Cadmium (Cd), a widespread environmental pollutant, has toxic effects on organs including spleen. However, the underlying mechanisms of Cd induced spleen toxicity and the roles of micro-RNA (miRNA) in this process remain poorly understood. To investigate this, cadmium chloride (CdCl2, 10 mg/kg) was administered in the diet of chickens for 90 days. Electron microscopy, qPCR and Western blot were performed. Results showed that Cd exposure suppressed miR-33-5q which increased the levels of AMPK. Subsequently, significant decrease in AKT/mTOR signaling and HSP70 were observed...
December 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/29221627/alkaline-diet-and-metabolic-acidosis-practical-approaches-to-the-nutritional-management-of-chronic-kidney-disease
#7
Larissa Rodrigues Neto Angéloco, Gabriela Cristina Arces de Souza, Elen Almeida Romão, Paula Garcia Chiarello
The kidneys play an extremely important role in maintaining the body acid-base balance by excreting nonvolatile acids and regenerating and reabsorbing bicarbonate in the kidney tubules. As the individual loses their kidney function, renal excretion of nonvolatile acid produced by metabolism of the diet is impaired, resulting in low-grade metabolic acidosis. With this in mind, it is relevant to better understand the dietary aspects related to the acid-base balance in chronic kidney disease metabolic acidosis and try to provide possible strategies for the nutritional management of these cases...
December 5, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29218015/trimethylamine-n-oxide-supplementation-abolishes-the-cardioprotective-effects-of-voluntary-exercise-in-mice-fed-a-western-diet
#8
Hongqi Zhang, Jian Meng, Haiyan Yu
Excessive consumption of western diet (WD) induces obesity, resulting in cardiac dysfunction. Voluntary exercise ameliorates WD-induced obesity, but its effect on cardiac dysfunction remains unclear. Recent evidence suggests that elevated trimethylamine N-oxide (TMAO), a gut microbe-derived metabolite, can impair cardiac function in WD-induced obesity. We hypothesized that cardiac dysfunction in WD-induced obesity would be prevented by voluntary exercise but abolished by TMAO supplementation. Male CD1 mice fed a WD were assigned to sedentary, exercise or exercise with TMAO treatment for 8 weeks...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29217477/activation-of-hepatic-nogo-b-receptor-expression-a-new-anti-liver-steatosis-mechanism-of-statins
#9
Wenwen Zhang, Xiaoxiao Yang, Yuanli Chen, Wenquan Hu, Lipei Liu, Xiaomeng Zhang, Mengyang Liu, Lei Sun, Ying Liu, Miao Yu, Xiaoju Li, Luyuan Li, Yan Zhu, Qing Robert Miao, Jihong Han, Yajun Duan
Deficiency of hepatic Nogo-B receptor (NgBR) expression activates liver X receptor α (LXRα) in an adenosine monophosphate-activated protein kinase α (AMPKα)-dependent manner, thereby inducing severe hepatic lipid accumulation and hypertriglyceridemia. Statins have been demonstrated non-cholesterol lowering effects including anti-nonalcoholic fatty liver disease (NAFLD). Herein, we investigated if the anti-NAFLD function of statins depends on activation of NgBR expression. In vivo, atorvastatin protected apoE deficient or NgBR floxed, but not hepatic NgBR deficient mice, against Western diet (WD)-increased triglyceride levels in liver and serum...
December 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29217211/mediating-effects-of-cancer-risk-factors-on-the-association-between-race-and-cancer-incidence-analysis-of-the-nih-aarp-diet-and-health-study
#10
Tomi Akinyemiju, Justin Xavier Moore, Maria Pisu
PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We performed prospective analysis of data from the National Institutes of Health-American Association of Retired Persons Diet and Health Study, years 1995 through 2011. We compared differences in baseline characteristics between black and white participants using χ2 tests and Wilcoxon tests, as appropriate...
November 23, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29216638/microrna-122-inhibits-lipid-droplet-formation-and-hepatic-triglyceride-accumulation-via-yin-yang-1
#11
Guo-Yi Wu, Chen Rui, Ji-Qiao Chen, Eiketsu Sho, Shan-Shan Zhan, Xian-Wen Yuan, Yi-Tao Ding
BACKGROUND/AIMS: An increase in intracellular lipid droplet formation and hepatic triglyceride (TG) content usually results in nonalcoholic fatty liver disease. However, the mechanisms underlying the regulation of hepatic TG homeostasis remain unclear. METHODS: Oil red O staining and TG measurement were performed to determine the lipid content. miRNA expression was evaluated by quantitative PCR. A luciferase assay was performed to validate the regulation of Yin Yang 1 (YY1) by microRNA (miR)-122...
December 6, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29216301/chronic-dietary-supplementation-with-soy-protein-improves-muscle-function-in-rats
#12
Ramzi J Khairallah, Karen M O'Shea, Christopher W Ward, Dustie N Butteiger, Ratna Mukherjea, Elaine S Krul
Athletes as well as elderly or hospitalized patients use dietary protein supplementation to maintain or grow skeletal muscle. It is recognized that high quality protein is needed for muscle accretion, and can be obtained from both animal and plant-based sources. There is interest to understand whether these sources differ in their ability to maintain or stimulate muscle growth and function. In this study, baseline muscle performance was assessed in 50 adult Sprague-Dawley rats after which they were assigned to one of five semi-purified "Western" diets (n = 10/group) differing only in protein source, namely 19 kcal% protein from either milk protein isolate (MPI), whey protein isolate (WPI), soy protein isolate (SPI), soy protein concentrate (SPC) or enzyme-treated soy protein (SPE)...
2017: PloS One
https://www.readbyqxmd.com/read/29215374/empirically-derived-dietary-patterns-and-ovarian-cancer-risk-a-meta-analysis
#13
Hai-Fang Wang, Ai-Lin Yao, Yan-Yan Sun, Ai-Hua Zhang
Dietary patterns, which reflect overall diet and possible nutrient and food interactions, have been reported to be related to ovarian cancer (OC) risk. However, studies on the relationship between dietary patterns and OC risk have been inconsistent. Thus, we carried out a systematic meta-analysis to assess the relationship between dietary patterns and the risk of OC. Relevant studies are identified by searching the Medline and Embase electronic databases up to December 2016. The Cochrane Q statistic and the I statistical were used to evaluate heterogeneity...
December 5, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29214021/a-pilot-study-with-early-adolescents-dealing-with-diet-tobacco-and-air-pollution-using-practical-experiences-and-biological-markers
#14
Chiara Marabelli, Elena Munarini, Micaela Lina, Roberto Mazza, Roberto Boffi, Cinzia De Marco, Ario Ruprecht, Giorgia Angellotti, Chiara Veronese, Paolo Pozzi, Eleonora Bruno, Giuliana Gargano, Adalberto Cavalleri, Giulia Garrone, Franco Berrino
Background: Tobacco use and the Western diet are two of the most important and investigated topics in relation to adolescents' health. In addition, air pollution is a crucial subject for future generations. School is a key social environment that should promote healthy behaviors in children and adolescents. In this field many different programs have been conducted, with mixed results and effectiveness. Research data suggest that comprehensive and multicomponent approaches may have a greater effect on tobacco use and diet, especially when integrated into a community-wide approach...
2017: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29213335/liraglutide-attenuates-atherosclerosis-via-inhibiting-er-induced-macrophage-derived-microvesicles-production-in-t2dm-rats
#15
Jinjin Li, Xiaojuan Liu, Qianhua Fang, Min Ding, Chunjun Li
Background: We investigated the effects of liraglutide on the formation and progression of atherosclerosis in type 2 diabetes mellitus (T2DM) rats. Methods: Sprague-Dawley rats were divided into control group, diabetes group and liraglutide treated group. The T2DM rats model with atherosclerosis were induced by high fat diet followed small dosage streptozotocin injection. Body weight and blood glucose levels were monitored once a week for 3 months and then the rats were sacrificed...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29211809/down-regulation-of-the-klf5-c-myc-interaction-due-to-klf5-phosphorylation-mediates-resveratrol-repressing-the-caveolin-1-transcription-through-the-pi3k-pkd1-akt-pathway
#16
Hui Yang, Qiuxia Chen, Fangyun Sun, Nana Zhao, Lirong Wen, Lin Li, Gai Ran
Resveratrol (RSV), a natural polyphenol, has been reported to produce effect on genes transcription in lipid metabolism. In this study, we aim to explore the novel mechanisms of RSV on the regulation of caveolin-1 (Cav-1) transcription. Via body weight, blood glucose, serum lipid, and liver pathology detection, we found that RSV decreased body weight, blood glucose and lipid accumulation in rats fed high-fat diet. Based on co-immunoprecipitation (Co-IP) and western blotting assay, we found that RSV up-regulated klf5 phosphorylation and decreased the interaction of klf5 with c-Myc, which were accompanied by down-regulation of Cav-1 expression in livers of rats fed with high-fat diet...
2017: PloS One
https://www.readbyqxmd.com/read/29211753/response-of-pumas-puma-concolor-to-migration-of-their-primary-prey-in-patagonia
#17
Maria L Gelin, Lyn C Branch, Daniel H Thornton, Andrés J Novaro, Matthew J Gould, Anthony Caragiulo
Large-scale ungulate migrations result in changes in prey availability for top predators and, as a consequence, can alter predator behavior. Migration may include entire populations of prey species, but often prey populations exhibit partial migration with some individuals remaining resident and others migrating. Interactions of migratory prey and predators have been documented in North America and some other parts of the world, but are poorly studied in South America. We examined the response of pumas (Puma concolor) to seasonal migration of guanacos (Lama guanicoe) in La Payunia Reserve in northern Patagonia Argentina, which is the site of the longest known ungulate migration in South America...
2017: PloS One
https://www.readbyqxmd.com/read/29210870/learning-needs-of-hospitalized-patients-with-heart-failure-in-singapore-a-descriptive-correlational-study
#18
Shu-Fen Ong, Pamela Pei-Mei Foong, Juanna Shen-Hwei Seah, Lavanya Elangovan, Wenru Wang
BACKGROUND: Understanding the learning needs of patients with heart failure (HF) is important in reducing the incidence of HF-related hospital readmissions. Sociocultural differences are known to influence patient learning needs. However, most HF learning needs studies have been conducted on Western populations. PURPOSE: The aim of this study was to investigate the learning needs of hospitalized patients with HF in Singapore. METHODS: A cross-sectional, descriptive correlational design was adopted using a questionnaire survey that included the Heart Failure Learning Needs Inventory and sociodemographic and clinical datasheets...
November 28, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29210099/behavioral-and-hormonal-responses-to-the-availability-of-forage-material-in-western-lowland-gorillas-gorilla-gorilla-gorilla
#19
Grace Fuller, Anna Murray, Melissa Thueme, Molly McGuire, Jennifer Vonk, Stephanie Allard
We investigated how forage material affects indicators of welfare in three male Western lowland gorillas (Gorilla gorilla gorilla) at the Detroit Zoo. In addition to their maintenance diet and enrichment foods, the gorillas generally received forage material four times a week. From this baseline, we systematically manipulated how much forage material the group received on a weekly basis, with either daily or bi (twice)-weekly presentation of browse (mulberry, Morus sp.) or alfalfa hay. We collected behavioral data (60 hr per gorilla) and measured fecal glucocorticoid metabolites (FGM)...
December 6, 2017: Zoo Biology
https://www.readbyqxmd.com/read/29209827/hemostasis-endothelial-stress-inflammation-and-the-metabolic-syndrome
#20
REVIEW
Gerald Grandl, Christian Wolfrum
Obesity and the metabolic syndrome (MS) are two of the pressing healthcare problems of our time. The MS is defined as increased abdominal obesity in concert with elevated fasting glucose levels, insulin resistance, elevated blood pressure, and plasma lipids. It is a key risk factor for type 2 diabetes mellitus (T2DM) and for cardiovascular complications and mortality. Here, we review work demonstrating that various aspects of coagulation and hemostasis, as well as vascular reactivity and function, become impaired progressively during chronic ingestion of a western diet, but also acutely after meals...
December 5, 2017: Seminars in Immunopathology
keyword
keyword
62384
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"