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https://www.readbyqxmd.com/read/28087761/proteomics-technologies-and-their-applications
#1
REVIEW
Bilal Aslam, Madiha Basit, Muhammad Atif Nisar, Mohsin Khurshid, Muhammad Hidayat Rasool
Proteomics involves the applications of technologies for the identification and quantification of overall proteins present content of a cell, tissue or an organism. It supplements the other "omics" technologies such as genomic and transcriptomics to expound the identity of proteins of an organism, and to cognize the structure and functions of a particular protein. Proteomics-based technologies are utilized in various capacities for different research settings such as detection of various diagnostic markers, candidates for vaccine production, understanding pathogenicity mechanisms, alteration of expression patterns in response to different signals and interpretation of functional protein pathways in different diseases...
February 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28079865/differences-in-mortality-characteristics-in-neonates-with-down-s-syndrome
#2
C L Cua, U Haque, S Santoro, L Nicholson, C H Backes
OBJECTIVE: Neonates with Down's syndrome (nDS) may have multiple medical issues that place them at increased risk for mortality during the newborn period. Goal of this study was to determine if there are differences in baseline characteristics, medical complications or procedures performed during hospitalization between nDS who survived versus those who died during initial hospitalization. STUDY DESIGN: Data from 2000 to 2014 were reviewed using the Pediatric Health Information Systems (PHIS) database on all DS patients admitted to the hospital <30 days postnatal life...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28074358/genotype-3-infection-the-last-stand-of-hepatitis-c-virus
#3
Austin Chan, Keyur Patel, Susanna Naggie
Hepatitis C virus (HCV) represents a significant global disease burden, with an estimated 130-150 million people worldwide living with chronic HCV infection. Within the six major clinical HCV genotypes, genotype 3 represents 22-30% of all infection and is described as a unique entity with higher rates of steatosis, faster progression to cirrhosis, and higher rates of hepatocellular carcinoma. Hepatic steatosis in the setting of hepatitis C genotype 3 (HCV-3) is driven by viral influence on three major pathways: microsomal triglyceride transfer protein, sterol regulatory element-binding protein-1c, and peroxisome proliferator-associated receptor-α...
January 10, 2017: Drugs
https://www.readbyqxmd.com/read/28071936/concussion-baseline-testing-preexisting-factors-symptoms-and-neurocognitive-performance
#4
Eric Hall, Jordan Cottle, Caroline Ketcham, Kirtida Patel, Kenneth P Barnes
CONTEXT:  Neurocognitive test scores are often considered an important aspect of concussion management. To best use these data, clinicians must understand potential factors that may influence baseline performance on these tests. OBJECTIVE:  To determine preexisting factors that may influence performance on the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT). DESIGN:  Cross-sectional study. SETTING:  Research laboratory...
January 10, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28068155/the-cost-of-survival-an-exploration-of-colorectal-cancer-survivors-experiences-of-pain
#5
Amanda Drury, Sheila Payne, Anne-Marie Brady
BACKGROUND: The Institute of Medicine report 'From Cancer Patient to Cancer Survivor' has drawn widespread attention to the experiences of cancer survivors. Research examining the symptom experiences of survivors are proliferative within the literature but limited by samples which include multiple tumor groups and varying inclusion criteria. This cross-sectional quantitative study seeks to examine pain and quality of life (QoL) in the context of colorectal cancer (CRC) survivorship, as defined by the Institute of Medicine...
January 9, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28055997/-bidirectional-impact-of-two-chronic-diseases-heart-failure-and-diabetes-mellitus
#6
José D Tafur, Héctor O Ventura
Heart failure remains a significant burden to healthcare systems. Even of the advances in medical therapy, heart failure morbidity and mortality have not been significantly reduced. Diabetes mellitus has shown to be a significant risk factor for the development and prognosis of heart failure. Traditionally, these two chronic illnesses have been managed in relative isolation. Clinicians should be more cognizant of the bidirectional impact between heart failure and diabetes.
December 27, 2016: Medwave
https://www.readbyqxmd.com/read/28046147/bill-e-kunkle-interdisciplinary-beef-symposium-assessing-the-mineral-supplementation-needs-in-pasture-based-beef-operations-in-the-southeastern-united-states
#7
L W Greene
Macro- and microminerals are required for all physiological processes in beef cattle. When mineral deficiencies occur in pasture-based production systems, a multitude of deficiency symptoms may occur, and most often, these deficiencies result in hidden losses to include reduced production potential, reduced immunity, and reproductive failure. More severe deficiencies will result in specific deficiency symptoms, depending on the specific mineral deficiency. In pasture-based beef operations, specific deficiency symptoms are seldom observed...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28026889/genomic-data-detect-corresponding-signatures-of-population-size-change-on-an-ecological-time-scale-in-two-salamander-species
#8
Schyler O Nunziata, Stacey L Lance, David E Scott, Emily Moriarty Lemmon, David W Weisrock
Understanding the demography of species over recent history (e.g., < 100 years) is critical in studies of ecology and evolution, but records of population history are rarely available. Surveying genetic variation is a potential alternative to census-based estimates of population size, and can yield insight into the demography of a population. However, to assess the performance of genetic methods it is important to compare their estimates of population history to known demography. Here, we leveraged the exceptional resources from a wetland with 37 years of amphibian mark-recapture data to study the utility of genetically-based demographic inference on salamander species with documented population declines (Ambystoma talpoideum) and expansions (A...
December 27, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/28007364/factor-eight-inhibitor-bypassing-agent-feiba-for-reversal-of-target-specific-oral-anticoagulants-in-life-threatening-intracranial-bleeding
#9
Gordon Mao, Lauren King, Sarah Young, Richard Kaplan
INTRODUCTION: As increasing number of patients present to emergency departments with life threatening hemorrhages, particularly intracranial hemorrhage on anticoagulation physicians must be cognizant of the limitations of the available reversal options. Based upon the available literature, our institution formulated a reversal algorithm for patients with life-threatening bleeding on factor Xa inhibitors by administering factor eight inhibitor bypassing agent (FEIBA) 20 units/kg. METHODS: A retrospective chart review was performed to include all patients who received FEIBA per institutional protocol...
December 19, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28006107/classification-and-analysis-of-attritional-glenoid-bone-loss-in-recurrent-anterior-shoulder-instability
#10
John W McNeil, Brendin R Beaulieu-Jones, Andrew S Bernhardson, Lance E LeClere, Christopher B Dewing, Joseph R Lynch, Petar Golijanin, George Sanchez, Matthew T Provencher
BACKGROUND: Recognition and proper treatment of glenoid bone loss (GBL) are important for successful management of anterior shoulder instability. Although GBL has been described as the amount of bony loss from the front of the glenoid, there is also a fragment of bone that is usually displaced and often undergoes attrition. Thus, due to attritional bone loss (ABL) of the fragment, insufficient bone is left to fully reconstruct the glenoid. PURPOSE: To (1) evaluate ABL of the glenoid fragment in recurrent anterior shoulder instability and (2) correlate ABL with clinical history, fragment size, and radiographic findings...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27994639/interpreting-comprehensive-two-dimensional-gas-chromatography-using-peak-topography-maps-with-application-to-petroleum-forensics
#11
Hamidreza Ghasemi Damavandi, Ananya Sen Gupta, Robert K Nelson, Christopher M Reddy
BACKGROUND: Comprehensive two-dimensional gas chromatography [Formula: see text] provides high-resolution separations across hundreds of compounds in a complex mixture, thus unlocking unprecedented information for intricate quantitative interpretation. We exploit this compound diversity across the [Formula: see text] topography to provide quantitative compound-cognizant interpretation beyond target compound analysis with petroleum forensics as a practical application. We focus on the [Formula: see text] topography of biomarker hydrocarbons, hopanes and steranes, as they are generally recalcitrant to weathering...
2016: Chemistry Central Journal
https://www.readbyqxmd.com/read/27990703/-you-never-come-back-the-same-the-challenge-of-spiritual-care-in-a-deployed-military-nursing-context
#12
Andrew Ormsby, Ann Harrington, Sally Borbasi
AIMS AND OBJECTIVES: To explore the experience of spirituality and spiritual care by military nurses on deployed operations. BACKGROUND: Despite an increasing body of research addressing spirituality in nursing care in a variety of clinical settings, the deployed military nursing context remains poorly understood. DESIGN: A qualitative, philosophical hermeneutic design. METHOD: Ten Australian military nurses were interviewed about their experiences of spirituality and spiritual care while on deployed operations...
December 19, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27941493/early-infant-diagnosis-of-hiv-review-of-current-and-innovative-practices
#13
Francesca Celletti, Gayle Sherman, Ahmad H Mazanderani
PURPOSE OF REVIEW: Only 51% of HIV-exposed infants receive an HIV test between 4 and 6 weeks of age, with even lower repeat testing rates at older ages, and only 49% of infants tested are initiated on antiretroviral therapy. The purpose of this article is to discuss potential solutions for increasing coverage of early infant diagnosis (EID), decreasing turnaround time for result return, improving linkages to care and treatment and fulfilling the objective of improving outcomes for HIV-infected children...
December 9, 2016: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/27924241/sleep-and-fatigue-among-seafarers-the-role-of-environmental-stressors-duration-at-sea-and-psychological-capital
#14
Sigurd W Hystad, Jarle Eid
BACKGROUND: Seafaring is an inherently stressful environment. Because working time and leisure time is spent in the same confined environment for a prolonged period of time, many stressors present in seafaring can also be conceived of as chronic. We explored the effects of duration at sea, seafaring experience, environmental stressors, and psychological capital (PsyCap) on the sleep quality and fatigue of seafarers. PsyCap is a construct that draws upon ideas from positive psychology and positive organizational behavior, and is intended to capture an individual's psychological capacities that can be developed and utilized for performance improvements...
December 2016: Safety and Health At Work
https://www.readbyqxmd.com/read/27910723/powered-mobility-intervention-understanding-the-position-of-tool-use-learning-as-part-of-implementing-the-alp-tool
#15
Lisbeth Nilsson, Josephine Durkin
PURPOSE: To explore the knowledge necessary for adoption and implementation of the Assessment of Learning Powered mobility use (ALP) tool in different practice settings for both adults and children. To consult with a diverse population of professionals working with adults and children, in different countries and various settings; who were learning about or using the ALP tool, as part of exploring and implementing research findings. METHOD: Classical grounded theory with a rigorous comparative analysis of data from informants together with reflections on our own rich experiences of powered mobility practice and comparisons with the literature...
December 2, 2016: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/27903077/approaches-to-learning-among-occupational-therapy-undergraduate-students-a-cross-cultural-study
#16
Ted Brown, Kenneth N K Fong, Tore Bonsaksen, Tan Hwei Lan, Yuki Murdolo, Pablo Cruz Gonzalez, Lim Hua Beng
BACKGROUND: Students may adopt various approaches to academic learning. Occupational therapy students' approaches to study and the impact of cultural context have not been formally investigated to date. AIM: To examine the approaches to study adopted by undergraduate occupational therapy students from four different cultural settings. METHOD: 712 undergraduate occupational therapy students (n = 376 from Australia, n = 109 from Hong Kong, n = 160 from Norway and n = 67 from Singapore) completed the Approaches and Study Skills Inventory for Students (ASSIST)...
November 30, 2016: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/27900477/the-influence-of-seasonality-and-manufacturer-kit-lot-changes-on-17%C3%AE-hydroxyprogesterone-measurements-and-referral-rates-of-congenital-adrenal-hyperplasia-in-newborns
#17
Melissa Pearce, Erin Dauerer, A Gregory DiRienzo, Michele Caggana, Norma P Tavakoli
: Newborn screening for congenital adrenal hyperplasia (CAH) is performed by measuring the concentration of 17α-hydroxyprogesterone (17-OHP) in dried blood spots. Unfortunately, the level of 17-OHP varies due to multiple factors, and therefore, the false positive rate for the test is a challenge. We analyzed screening data from 2007 to 2015 to determine the effect of seasonal changes and manufacturer kit lot changes on 17-OHP values and on numbers of infants referred. Data from screening 2...
January 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27900182/concussion-reporting-behaviours-of-community-college-student-athletes-and-limits-of-transferring-concussion-knowledge-during-the-stress-of-competition
#18
Nancy Resendes Chinn, Paul Porter
: Concussion education for student-athletes is mandated by several states and is becoming an integral component of concussion management programmes; however, little is known about student-athlete concussion knowledge and self-reporting of suspected concussion. This study explored to what extent collegiate student-athletes are knowledgeable on the topic of concussion, the relationship between having concussion knowledge and reporting behaviours, and factors contributing to not reporting when education has been provided...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27889825/a-critical-review-of-complementary-and-alternative-medicine-use-among-people-with-arthritis-a-focus-upon-prevalence-cost-user-profiles-motivation-decision-making-perceived-benefits-and-communication
#19
REVIEW
Lu Yang, David Sibbritt, Jon Adams
A critical review of complementary and alternative medicine (CAM) use among people with arthritis was conducted focusing upon prevalence and profile of CAM users as well as their motivation, decision-making, perceived benefits and communication with healthcare providers. A comprehensive search of peer-reviewed literature published from 2008 to 2015 was undertaken via CINAHL, Medline and AMED databases. The initial search identified 4331 articles, of which 49 articles met selection criteria. The review shows a high prevalence of CAM use (often multiple types and concurrent to conventional medical care) among those with arthritis which is not restricted to any particular geographic or social-economic status...
November 26, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27888022/intentions-and-barriers-toward-breastfeeding-among-jordanian-mothers-a-cross-sectional-descriptive-study-using-quantitative-method
#20
Ahmad Yahya Al-Sagarat, Ghada Yaghmour, Lorna Moxham
PROBLEM/BACKGROUND: Breastfeeding is very important for both mother and infant. Within Jordanian hospitals, intentions and barriers to breastfeeding have not been addressed effectively during preparing policies in routine antenatal care or in maternal and child health care. AIM: To identify the intentions and barriers toward breastfeeding among Jordanian mothers with a specific focus on women from low income circumstances. METHODS: A cross-sectional descriptive study using quantitative methods was adopted in this study...
November 22, 2016: Women and Birth: Journal of the Australian College of Midwives
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