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https://www.readbyqxmd.com/read/29773698/protocol-for-the-validation-of-sensitivity-and-specificity-of-the-cow-s-milk-related-symptom-score-comiss-against-open-food-challenge-in-a-single-blinded-prospective-multicentre-trial-in-infants
#1
Yvan Vandenplas, Rajat Mukherjee, Christophe Dupont, Philippe Eigenmann, Arne Høst, Mikael Kuitunen, Carmen Ribes-Koninkx, Neil Shah, Hania Szajewska, Andrea von Berg, Ralf G Heine, Zheng-Yan Zhao
INTRODUCTION: The symptoms of cow's milk protein allergy (CMPA) in infancy can be non-specific which may delay a correct diagnosis and cause adverse clinical outcomes. The diagnosis of non-IgE-mediated CMPA is particularly complex as it involves a 2 to 4 week elimination diet followed by oral food challenge (OFC). The Cow's Milk-related Symptom Score (CoMiSS) is a clinical resource for primary healthcare providers which aims to increase awareness of CMPA symptoms to facilitate an earlier diagnosis...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29750635/mechanism-research-of-bu-shen-huo-xue-formula-against-renal-fibrosis-in-rats-with-5-6-nephrectomy-via-e-cadherin-%C3%AE-sma-and-tgf-%C3%AE-1
#2
Jian-Rao Lu, Hai-Yan Han, Jing Hu, Chuan-Fu Zhang, Jie Chen, Xiu-Feng Chen, Xin-Hua Wang, Rong-Hua Pan
OBJECTIVE: Renal fibrosis generally results in renal failure during the end stage of chronic renal diseases. There are many cell factors including E-cadherin, α-SMA, and TGF-β1 influencing deposition of extracellular matrix and leading to renal fibrosis. As the most important and widely-used therapy for various diseases in China for thousands of years, traditional Chinese medicine (TCM) provides a novel treatment for renal fibrosis. For clinical application, we explore the effect of Bu-Shen-Huo-Xue formula (BSHX), a traditional Chinese herbal formula, on E-cadherin and α-SMA in rats with 5/6 nephrectomy...
May 11, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29736654/in-depth-molecular-characterization-and-biodegradability-of-water-extractable-organic-nitrogen-in-erhai-lake-sediment
#3
Li Zhang, Shengrui Wang, Jiachun Yang, Kechen Xu
Dissolved organic nitrogen (DON) constitutes a significant fraction of the total dissolved nitrogen content of most aquatic systems and is thus a major nitrogen source for bacteria and phytoplankton. The present work applied Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) to a compound-level analysis of the depth-dependent molecular composition of water-extractable organic nitrogen (WEON) in lake sediment. The study focused on Erhai Lake, China. It was found that a large portion (from 16...
May 8, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29724345/phylogeny-morphology-and-toxicity-of-benthic-dinoflagellates-of-the-genus-fukuyoa-goniodomataceae-dinophyceae-from-a-subtropical-reef-ecosystem-in-the-south-china-sea
#4
Priscilla T Y Leung, Meng Yan, Veronica T T Lam, Sam K F Yiu, Chia-Yun Chen, J Sam Murray, D Tim Harwood, Lesley L Rhodes, Paul K S Lam, Tak-Cheung Wai
Species of Fukuyoa, recently revised from the globular Gambierdiscus, are toxic benthic dinoflagellates associated with ciguatera. In this study, a total of ten strains of Fukuyoa collected from Hong Kong waters were characterized using morphological and phylogenetic analyses. Results from both analyses showed that one of the strains is a putative new species, namely Fukuyoa sp. HK Type 1 (plate formula Po, 3', 7″, 6c, 7s, 5‴, 1p and 2'‴ with a distinctive small and narrow cell shape, narrow Po plate, high Po pore density, large and broad Plate 1' but small and round Po pore size, small and narrow Plate 2', long and narrow Plates 2'‴ and 1p), and the others were F...
April 2018: Harmful Algae
https://www.readbyqxmd.com/read/29712960/association-patterns-of-urinary-sodium-potassium-and-their-ratio-with-blood-pressure-across-various-levels-of-salt-diet-regions-in-china
#5
Lu Yin, Guijuan Deng, Andrew Mente, Yi Sun, Xiaoyun Liu, Xinhua Zhang, Xingyu Wang, Yang Wang, Jian Bo, Hui Chen, Xu Liu, Nan Gao, Xiulin Bai, Sumathy Rangarajan, Wei Li
We aim to evaluate the association of systolic and diastolic blood pressure (SBP and DBP) with estimated urinary sodium (Na) and potassium(K) excretions, and their gram-to-gram Na/K ratio across various salt-diet regions during 2005-2009 in China. A prospective cohort study was conducted to recruit 46,285 participants in China. A single fasting morning urine specimen was collected to estimate 24-hour urinary Na and K excretion using Kawasaki formula. Means of estimated Na and K were 5.7 ± 1.7 and 2.1 ± 0...
April 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29707037/efficacy-and-safety-of-a-formulated-herbal-granula-jiu-wei-zhen-xin-for-generalized-anxiety-disorder-a-meta-analysis
#6
Sheng Wang, Lin-Lin Zhao, Xin-Jian Qiu, Dong-Sheng Wang, Tao Tang, Jie-Kun Luo, Sui-Yu Hu, Hui-Yong Huang
Background: The traditional Chinese medicine formula Jiu Wei Zhen Xin Granula (JWZXG) is prescribed to treat generalized anxiety disorder (GAD) in China. This study was to assess the efficacy and safety of JWZXG in patients with GAD. Method: Data were pooled from 14 randomized controlled trials involving the assessment of mean changes of Hamilton Anxiety Rating Scale (HAMA) total scores, response rates, adverse event rates, quality, publication bias, and risk of bias...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29706777/lithobius-ezembius-tetraspinus-a-new-species-of-centipede-from-northwest-china-lithobiomorpha-lithobiidae
#7
Sujian Pei, Yanmin Lu, Haipeng Liu, Xiaojie Hou, Huiqin Ma
Lithobius (Ezembius) tetraspinus sp. n. (Lithobiomorpha: Lithobiidae), recently discovered from Hami City, Xinjiang Autonomous Region, NW China, is described. Morphologically this species resembles L. (E.) sibiricus, Gersfeldt, 1858, but is distinguishable by a different coxal pore formula, absence of accessory spurs on leg 15, morphology of the second article of the female gonopod, and legs 14 plectrotaxy. A table of the main morphological characters of Chinese Lithobius (Ezembius) species is presented.
2018: ZooKeys
https://www.readbyqxmd.com/read/29706775/four-new-species-of-the-glyphiulus-javanicus-group-from-southern-china-diplopoda-spirostreptida-cambalopsidae
#8
Xuankong Jiang, Xuan Guo, Huiming Chen, Zhicai Xie
Hitherto, 24 species of the Glyphiulus javanicus group have been recorded, all endemic to Southeast Asia, including 14 in China. Nevertheless, this species group needs further exploration. In this context, four new species of this group are described, all collected from limestone caves in Southern China: G. calceus sp. n. , G. foetidus sp. n. , G. guangnanensis sp. n. , and G. impletus sp. n. They can be separated easily from each other and other congeners by their carinotaxic formulae, the structures of male legs I, and the gonopods...
2018: ZooKeys
https://www.readbyqxmd.com/read/29690410/a-new-species-of-hemiphyllodactylus-squamata-gekkonidae-from-hong-kong
#9
Yik-Hei Sung, Wing-Ho Lee, Ho-Nam Ng, Yanjie Zhang, Jian-Huan Yang
A new species of gekkonid, Hemiphyllodactylus hongkongensis sp. nov., is described based on a series of specimens collected from Hong Kong SAR, China. The new species can be distinguished from other known congeners by molecular divergence in the mitochondrial ND2 gene and morphological characters including 5-6 chin scales; a manual lamellar formula of 3-3(4)-4-4; a pedal lamellar formula of 3(4)-4(5)-4(5)-4; 24-25 continuous femoral and precloacal pores; 12-15 dorsal scales and 9-10 ventral scales contained in diameter of eye...
March 8, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690243/two-new-chinese-species-of-tomocerus-at-different-stages-of-troglomorphic-adaptation-collembola-tomoceridae
#10
Daoyuan Yu, Louis Deharveng
Two new species of Tomocerus are described from caves in Guizhou and Guangxi Province, China. Tomocerus troglodytes sp. nov. is highly troglomorphic. It belongs to the kinoshitai complex, and is most similar to another eyeless and colourless species Tomocerus caecus, from which it differs as it has longer antennae; 2,2/2,2/2+2/0 versus 2,2/2,5/0/0 cephalic dorsal chaetotaxy formula; 6 versus 4 central macrochaetae on Th. II; 0 versus 2 ungual teeth; unguis devoid of baso-internal ridges; 3-5/3-5, I, 0-1, I versus 4-5/1-2,I-II,0-1,I-II dental spines formula; 2-4 versus 1 tenacular chaetae; and 0 versus 1 mucronal intermediate teeth...
April 3, 2018: Zootaxa
https://www.readbyqxmd.com/read/29686701/nontyphoidal-salmonella-gastroenteritis-in-a-tertiary-children-s-hospital-in-southern-china-characteristics-and-dietary-considerations
#11
Lu Ren, Min Yang, Lanlan Geng, Peiyu Chen, Huan Chen, Sitang Gong, Ding-You Li
Background: Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children's hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29686614/traditional-chinese-medicine-for-bradyarrhythmia-evidence-and-potential-mechanisms
#12
Shuo Liu, Guihua Tian, Jing Chen, Xiaoyu Zhang, Aiming Wu, Min Li, Yang Sun, Baoshan Liu, Yanwei Xing, Hongcai Shang
Importance: The incidence of Bradyarrhythmias is high among the population. However, at early stages of the disease, it cannot always get enough attention and is lack of safe and effective therapies, until it is serious enough to resort to pacemaker implantation. Traditional Chinese Medicine (TCM) has a long history of treating Bradyarrhythmia, with a lot of formulas being widely used in clinical practice. While the effectiveness and the underlying mechanisms of these formulas have not yet been clearly identified...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29668624/effect-of-%C3%AF-3-polyunsaturated-fatty-acid-supplemented-parenteral-nutrition-on-inflammatory-and-immune-function-in-postoperative-patients-with-gastrointestinal-malignancy-a-meta-analysis-of-randomized-control-trials-in-china
#13
Yajie Zhao, Chengfeng Wang
BACKGROUND: There are no consensus regarding the efficacy of omega-3polyunsaturated fatty acids (PUFAs) on inflammatory and immune function in postoperative patients with gastrointestinal malignancy. METHODS: The literatures published randomized control trials (RCT) were searched in PubMed, Embase, Scopus, Cochrane Library, CNKI, Weipu, and Wanfang Databases. The immune efficacy outcomes of ω-3 polyunsaturated fatty acid-supplemented parenteral nutrition in patients with gastrointestinal malignancy were compared...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29660465/jageum-jung-improves-2-4-dinitrochlorobenzene-induced-atopic-dermatitis-like-skin-lesions-in-mice-and-suppresses-pro-inflammatory-chemokine-production-by-inhibiting-tnf-%C3%AE-ifn-%C3%AE-induced-stat-1-and-nf%C3%AE%C2%BAb-signaling-in-hacat-cells
#14
Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma
ETHNOPHARMACOLOGICAL RELEVANCE: Jageum-Jung (JGJ) is an oriental herbal formula comprising five herbs (Melaphis chinensis Bell, Cremastra variabilis Nakai, Knoxia valerianoides Thorel, Euphorbia lathyris L., and Moschus moschiferus L.). It has been used for detoxification and treating cancer and inflammatory diseases in China, Japan, and Korea. However, the mechanism of action of JGJ on keratinocyte inflammatory response is poorly understood. AIM OF THE STUDY: In the present study, we investigated the anti-inflammatory mechanism of JGJ and studied the effects of JGJ on atopic dermatitis-like skin lesions in mice...
April 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29651245/antiseptic-activity-of-ethnomedicinal-xuebijing-revealed-by-the-metabolomics-analysis-using-uhplc-q-orbitrap-hrms
#15
Lihua Zuo, Lin Zhou, Tanye Xu, Zhuolun Li, Liwei Liu, Yingying Shi, Jian Kang, Guanmin Gao, Shuzhang Du, Zhi Sun, Xiaojian Zhang
Xuebijing (XBJ) injection is an ethnomedicinal formula that has been widely used in the therapy of sepsis in China. However, the underlying theraputic mechanisms remain uninvestigated. In this research, a metabolomic method based on UHPLC-Q-Orbitrap HRMS was applied to make a holistic evaluation of XBJ on septic rats which were induced by the classical cecal ligation and puncture (CLP) operation. The plasma metabolic changes were profiled and evaluated by multivariate analytical (MVA) methods. In the results, a total of 41 differential metabolites were identified between CLP-operated group and sham-operated group, which were mainly involved in amino acid metabolism and lipid metabolism...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29644611/atmospheric-fossil-fuel-co-2-traced-by-14-co-2-and-air-quality-index-pollutant-observations-in-beijing-and-xiamen-china
#16
Zhenchuan Niu, Weijian Zhou, Xue Feng, Tian Feng, Shugang Wu, Peng Cheng, Xuefeng Lu, Hua Du, Xiaohu Xiong, Yunchong Fu
Radiocarbon (14 C) is the most accurate tracer available for quantifying atmospheric CO2 derived from fossil fuel (CO2ff ), but it is expensive and time-consuming to measure. Here, we used common hourly Air Quality Index (AQI) pollutants (AQI, PM2.5 , PM10 , and CO) to indirectly trace diurnal CO2ff variations during certain days at the urban sites in Beijing and Xiamen, China, based on linear relationships between AQI pollutants and CO2ff traced by 14 C ([Formula: see text]) for semimonthly samples obtained in 2014...
April 11, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29619064/a-traditional-herbal-formula-xianlinggubao-for-pain-control-and-function-improvement-in-patients-with-knee-and-hand-osteoarthritis-a-multicenter-randomized-open-label-controlled-trial
#17
Fei Wang, Lei Shi, Yaonan Zhang, Kunzheng Wang, Fuxing Pei, Hanmin Zhu, Zhanjun Shi, Tianzun Tao, Zhihua Li, Ping Zeng, Xiaobing Wang, Quan Ji, Ling Qin, Qingxun Xue
Evidence of efficacy of a traditional herbal formula Xianlinggubao (XLGB) for treatment of osteoarthritis (OA) is limited. The present study was designed to evaluate the efficacy of XLGB in the management of patients with knee and hand OA. This was a multicenter, stratified, open-label, randomized controlled trial conducted at six centers in China. People aged 40 or above, diagnosed with OA of the knee or hand, were randomly assigned to the XLGB treatment group or watchful waiting control group. Main outcome measures were the changes in the numeric pain rating scales (NPRS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) or the Australian/Canadian Osteoarthritis Hand Index (AUSCAN) scores, from baseline to 6 months...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29599812/study-of-pharmacodynamic-and-pharmacokinetic-interaction-of-bojungikki-tang-with-aspirin-in-healthy-subjects-and-ischemic-stroke-patients
#18
Jung-Hwa Yoo, Sung-Vin Yim, Byung-Cheol Lee
Background: Bojungikki-tang (BJIKT) is a widely used traditional herbal formula in China, Japan, and Korea. There have been reports that several herbs among BJIKT have interactions with antiplatelet drugs, such as aspirin. This study aimed to assess whether BJIKT interacts with aspirin in terms of pharmacokinetics (PK) and pharmacodynamics (PD) in healthy subjects and ischemic stroke patients. Methods: The phase I interaction trial was a randomized, open-label, crossover study of 10 healthy male subjects, and the phase III interaction trial was a randomized, placebo-controlled, parallel study of 43 ischemic stroke patients...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29595636/evidence-based-practice-guideline-of-chinese-herbal-medicine-for-primary-open-angle-glaucoma-qingfeng-neizhang
#19
Yingxin Yang, Qiu-Yan Ma, Yue Yang, Yu-Peng He, Chao-Ting Ma, Qiang Li, Ming Jin, Wei Chen
BACKGROUND: Primary open angle glaucoma (POAG) is a chronic, progressive optic neuropathy. The aim was to develop an evidence-based clinical practice guideline of Chinese herbal medicine (CHM) for POAG with focus on Chinese medicine pattern differentiation and treatment as well as approved herbal proprietary medicine. METHODS: The guideline development group involved in various pieces of expertise in contents and methods. Authors searched electronic databases include CNKI, VIP, Sino-Med, Wanfang data, PubMed, the Cochrane Library, EMBASE, as well as checked China State Food and Drug Administration (SFDA) from the inception of these databases to June 30, 2015...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29587863/chinese-herbal-medicine-shenzhuo-formula-treatment-in-patients-with-macroalbuminuria-secondary-to-diabetic-kidney-disease-study-protocol-for-a-randomized-controlled-trial
#20
Xue-Min Zhao, Ying Zhang, Xin-Hui He, Hong-Dong Chen, Zhu-Feng Wang, Jing Guo, Xin-Miao Wang, Ze-Zheng Gao, Ji-Ping Wang, Wei Liu, Lin-Hua Zhao, Xiao-Lin Tong
BACKGROUND: Diabetic kidney disease (DKD) is a serious complication associated with diabetes mellitus and can cause end-stage renal disease (ESRD). Traditional Chinese medicine (TCM) is widely used in China to treat DKD, and in particular microalbuminuria and macroalbuminuria. This study will address the efficacy and safety of Shenzhuo Formula (SZF), a frequently prescribed TCM, in DKD patients with macroalbuminuria. METHODS/DESIGN: This study is a 24-week, randomized, multi-center, double-blinded, double-dummy, controlled, clinical trial that will include 120 DKD patients aged 18 to 80 years old with a 24-h urinary protein (24-h UP) level of between 0...
March 27, 2018: Trials
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