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https://www.readbyqxmd.com/read/28634136/tongxie-formula-reduces-symptoms-of-irritable-bowel-syndrome
#1
Heng Fan, Liang Zheng, Yaoliang Lai, Weimin Lu, Zhixiang Yan, Qi Xiao, Baiwen Li, Min Tang, Dawei Huang, Yuanyuan Wang, Zhen Li, Yuwei Mei, Zhengyan Jiang, Xingxing Liu, Qing Tang, Dongmei Zuo, Jingyi Ye, Yongqiang Yang, Huisuo Huang, Zongxiang Tang, Jun Xiao
BACKGROUND & AIMS: Irritable bowel syndrome (IBS) is the most common chronic gastrointestinal disorder, yet few drugs are effective in reducing symptoms. Approximately 50% of patients with IBS attempt herbal therapy at least once. We performed a randomized controlled trial to compare the efficacy of the herb formulation tongxie vs placebo or pinaverium (an antispasmodic agent) in reducing symptoms of IBS. METHODS: We performed a trial of 1044 adult patients with IBS (based on Rome III criteria) at 5 hospitals in China, from August 2012 through January 2015...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28630084/maternal-lifestyle-and-nutritional-status-in-relation-to-pregnancy-and-infant-health-outcomes-in-western-china-protocol-for-a-prospective-cohort-study
#2
Li Tang, Xiong-Fei Pan, Andy H Lee, Colin W Binns, Chun-Xia Yang, Xin Sun
INTRODUCTION: Improving the health and nutrition of women and children is a priority for Western China, where the economy is less developed. Due to the dynamic nature of lifestyle, modern food habits and nutrition, there is a need to update our limited knowledge and understanding of maternal lifestyle and nutritional status and their impact on pregnancy and infant health outcomes. While breast milk is the preferred feeding option, infant formula use is widespread in China. It is thus necessary to examine the effects of formula consumption on growth and morbidity...
June 19, 2017: BMJ Open
https://www.readbyqxmd.com/read/28629384/involvement-of-the-glutamate-glutamine-cycle-and-glutamate-transporter-glt-1-in-antidepressant-like-effects-of-xiao-yao-san-on-chronically-stressed-mice
#3
Xiu-Fang Ding, Yue-Hua Li, Jia-Xu Chen, Long-Ji Sun, Hai-Yan Jiao, Xin-Xin Wang, Yan Zhou
BACKGROUND: Xiao Yao San (XYS) is an herbal prescription which is used in the treatment of depression for thousands of years from Song dynasty in China (960-1127 A.D.), and is the bestselling and most popular herb formula for treating major depression. This study aimed to assess the chronic antidepressant effects of XYS and fluoxetine in depressed mice induced by chronic unpredictable mild stress (CUMS) and its association with  alterations in glutamate/glutamine cycle and glutamate transporters...
June 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28619773/herbal-medicine-hyeolbuchukeo-tang-or-xuefu-zhuyu-decoction-for-treating-primary-dysmenorrhoea-protocol-for-a-systematic-review-of-randomised-controlled-trials
#4
Junyoung Jo, Jungtae Leem, Jin Moo Lee, Kyoung Sun Park
INTRODUCTION: Primary dysmenorrhoea is menstrual pain without pelvic pathology and is the most common gynaecological condition in women. Xuefu Zhuyudecoction (XZD) or Hyeolbuchukeo-tang, a traditional herbal formula, has been used as a treatment for primary dysmenorrhoea. The purpose of this study is to assess the current published evidence regarding XZD as treatment for primary dysmenorrhoea. MATERIALS AND METHODS: The following databases will be searched from their inception until April 2017: MEDLINE (via PubMed), Allied and Complementary Medicine Database (AMED), EMBASE, The Cochrane Library, six Korean medical databases (Korean Studies Information Service System, DBPia, Oriental Medicine Advanced Searching Integrated System, Research Information Service System, Korea Med and the Korean Traditional Knowledge Portal), three Chinese medical databases (China National Knowledge Infrastructure (CNKI), Wan Fang Database and Chinese Scientific Journals Database (VIP)) and one Japanese medical database (CiNii)...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28606807/recent-pharmaceutical-evidence-on-the-compatibility-rationality-of-traditional-chinese-medicine
#5
REVIEW
Miaomiao Zhou, Yanlong Hong, Xiao Lin, Lan Shen, Yi Feng
ETHNOPHARMACOLOGICAL RELEVANCE: Chinese herbs have been used in China for thousands of years and are also becoming popular in Western medicine. Formulae of traditional Chinese medicine (TCM), which contain two or more herbs, can often obtain better curative efficacies and fewer side effects than single herbs. Though there are many reports on pharmaceutics, pharmacokinetics, and pharmacodynamics of TCM, there remains a serious lack of summarization and systemic analyses of these reported data to help uncover the compatibility rationale of TCM...
June 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28600727/evaluation-of-acidity-in-late-permian-outcrop-coals-and-its-association-with-endemic-fluorosis-in-the-border-area-of-yunnan-guizhou-and-sichuan-in-china
#6
Xiuping Hong, Handong Liang, Yufa Zhang
The junction area of Yunnan, Guizhou, and Sichuan provinces is the heaviest coal-burning endemic fluorosis zones in China. To better understand the pathogenicity of endemic fluorosis in this area, 87 coal samples from the late Permian outcrop or semi-outcrop coal seams were collected in eight counties of the junction area of Yunnan, Guizhou, and Sichuan provinces. The total fluorine and sulfate content, etc. in the coal was determined using combustion-hydrolysis/fluoride-ion-selective electrode method and ion chromatography, respectively...
June 9, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28591826/study-on-the-shielding-and-dose-rate-distributions-of-therapeutic-proton-synchrotron-accelerator-based-on-fluka
#7
Zhen Zhang, Changsong Hou, Dexing Lian, Zhongjian Ma, Junquan Tao, Weiguo Zhu
Some therapeutic proton synchrotron accelerators will be built for cancer treatment in China. The radiation produced by proton must be carefully evaluated and shielded for occupational disease hazard assessment and environmental impact assessment. Adopting the FLUKA code, a therapeutic room model, a synchrotron hall model and a high energy transport line tunnel model are constructed to get the ambient dose equivalent rate distributions. The ambient dose equivalent rates are also calculated with an empirical formula in some regions...
June 7, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28586073/effects-of-the-tangningtongluo-formula-as-an-alternative-strategy-for-diabetics-via-upregulation-of-insulin-receptor-substrate-1
#8
Long Cheng, Junmei Song, Geng Li, Yue Liu, Yuming Wang, Xiangbao Meng, Guibo Sun, Xiaobo Sun
Tangningtongluo (TNTL), a traditional Chinese medicine, has been widely used in clinics for decades in southwest China. Its pharmacological properties and underlying molecular mechanisms remain unclear. The main goal of ethnopharmacology is to identify novel bioactive compounds derived from plants for use in indigenous medical practice. This knowledge can be used to develop novel pharmaceuticals. In the present study, hyperglycemic C57BL/KsJ‑db/db (db/db) mice were used to test the effect of TNTL on microvasculature of the retina and hypoglycemia...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28557713/effects-of-prenatal-formula-see-text-exposure-on-fetal-cardiovascular-malformations-in-fuzhou-china-a-retrospective-case-control-study
#9
Chao-Bin Liu, Xin-Ru Hong, Miao Shi, Xiao-Qiu Chen, Hui-Juan Huang, Jin-Hua Chen, Kai Yang, Su-Qing Chen, Han-Qiang Chen, Hai-Dong Kan, Qing-Hua Sun
BACKGROUND: Maternal exposure to ambient air pollution has been associated with an increased risk of congenital heart defects in offspring; however, the results are inconsistent. OBJECTIVES: We investigated whether there is an association between prenatal exposure to particulate matter with diameter [Formula: see text] ([Formula: see text]) during early pregnancy and fetal cardiovascular malformations. METHODS: The gravidae from a hospital-based case-control study in Fuzhou, China, during 2007-2013 were assigned 10-d or 1-mo averages of daily [Formula: see text] using an air monitor-based inverse distance weighting method during early pregnancy...
May 25, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28555160/boi-ogi-to-tj-20-a-kampo-formula-suppresses-the-inflammatory-bone-destruction-and-the-expression-of-cytokines-in-the-synovia-of-ankle-joints-of-adjuvant-arthritic-rats
#10
Xinwen Zhang, Zhou Wu, Yicong Liu, Junjun Ni, Chunfu Deng, Baohong Zhao, Hiroshi Nakanishi, Jing He, Xu Yan
TJ-20 is a formula consisting of 6 herbs that has been used in the clinical treatment of rheumatoid arthritis (RA) in China and Japan for centuries. However, scientific evidence of the effects of TJ-20 has not been established. In the present study, we focused on the therapeutic effects and investigated the main function of TJ-20 on adjuvant arthritis (AA), an animal model of RA, which was induced with complete Freund's adjuvant (CFA). TJ-20 was administered orally at 600 mg/kg once a day from 0, 7, and 10 days to 8 weeks after the CFA treatment...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28553348/neuroprotective-mechanism-of-kai-xin-san-upregulation-of-hippocampal-insulin-degrading-enzyme-protein-expression-and-acceleration-of-amyloid-beta-degradation
#11
Na Wang, Yong-Ming Jia, Bo Zhang, Di Xue, Maharjan Reeju, Yan Li, Shu-Ming Huang, Xue-Wei Liu
Kai Xin San is a Chinese herbal formula composed of Radix Ginseng, Poria, Radix Polygalae and Acorus Tatarinowii Rhizome. It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-β (Aβ)-induced cognitive dysfunction and is neuroprotective in vivo, but its precise mechanism remains unclear. Expression of insulin-degrading enzyme (IDE), which degrades Aβ, is strongly correlated with cognitive function. Here, we injected rats with exogenous Aβ42 (200 μM, 5 μL) into the hippocampus and subsequently administered Kai Xin San (0...
April 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28545304/tracing-sources-of-nitrate-using-water-chemistry-land-use-and-nitrogen-isotopes-in-the-ganjiang-river-china
#12
Peng Wang, Junzheng Liu, Shuhua Qi, Shiqin Wang, Xiaoling Chen
In this work, we traced sources of nitrate in the Ganjiang River, a major tributary of Yangtze River, China, by analysing the water chemistry, nitrogen isotopes and land use. Water samples from 20 sites in the main stream and tributaries were collected in the dry and wet seasons. The [Formula: see text] ranged from 0.97 to 8.60 ‰, and was significantly higher in the wet season than in the dry season, and significantly higher in tributaries than in the main stream. In the dry season, [Formula: see text] concentrations and [Formula: see text] were significantly negatively correlated with forest and grassland areas, and positively correlated with paddy field and residential area...
May 25, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28544541/identification-and-analysis-of-chemical-constituents-and-rat-serum-metabolites-in-suan-zao-ren-granule-using-ultra-high-performance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-combined-with-multiple-data-processing-approaches
#13
Yiyang Du, Bosai He, Qing Li, Jiao He, Di Wang, Kaishun Bi
Suan-Zao-Ren granule is widely used to treat insomnia in China. However, because of the complexity and diversity of the chemical compositions in traditional Chinese medicine formula, the comprehensive analysis of constituents in vitro and in vivo are rather difficult. In our study, an ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry and the PeakView® software, which uses multiple data processing approaches including product ion filter, neutral loss filter and mass defect filter, method was developed to characterize the ingredients and rat serum metabolites in Suan-Zao-Ren granule...
May 24, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28521514/baicalein-attenuates-lung-injury-induced-by-myocardial-ischemia-and-reperfusion
#14
Chang-Chi Lai, Po-Hsun Huang, An-Han Yang, Shu-Chiung Chiang, Chia-Yu Tang, Kuo-Wei Tseng, Cheng-Hsiung Huang
Baicalein is an active component of Scutellaria baicalensis Georgi, which has traditionally been used to treat cardiovascular diseases in China. In this study, we investigated if treatment with baicalein can attenuate the lung injury induced by myocardial ischemia and reperfusion (I/R). Myocardial I/R, induced by a 40-min occlusion of the left anterior descending coronary artery and a 3-h reperfusion, significantly increased histological damage and the wet-to-dry weight ratio of lungs in rats. The terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)-positive nuclei and caspase-3 activation was significantly increased in the lungs...
May 18, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28512376/oscheius-microvilli-n-sp-nematoda-rhabditidae-a-facultatively-pathogenic-nematode-from-chongming-island-china
#15
Guixin Zhou, Huan Yang, Feng Wang, Haoran Bao, Guoxiang Wang, Xianglong Hou, Jian Lin, Gabriel Yedid, Keyun Zhang
A new species, Oscheius microvilli n. sp., was found on Chongming Island (Shanghai, China). The new species is morphologically similar to the type strain of Oscheius myriophilus, but can be distinguished from it and other species of Oscheius on the basis of unique morphological characteristics of the bursa as well as male papillae. In this new species, the male bursal papillar formula is 2, 1, 3, 3 with everted tips in the first, fifth, and seventh pairs. The bursal rim is jagged, joins together anterior to the spicules, and is partially extended and decorated with microvilli...
March 2017: Journal of Nematology
https://www.readbyqxmd.com/read/28507819/radix-stellariae-extract-prevents-high-fat-diet-induced-obesity-in-c57bl-6-mice-by-accelerating-energy-metabolism
#16
Yin Li, Xin Liu, Yu Fan, Baican Yang, Cheng Huang
Stellaria dichotoma L. is widely distributed in Ningxia and surrounding areas in northwestern China. Its root, Radix Stellariae (RS), has been used in herbal formulae for treating asthenic-fever, infection, malaria, dyspepsia in children and several other symptoms. This study investigated whether the RS extract (RSE) alleviates metabolic disorders. The results indicated that RSE significantly inhibited body weight gain in high-fat (HF)-diet-fed C57BL/6 mice, reduced fasting glucose levels, and improved insulin tolerance...
2017: PeerJ
https://www.readbyqxmd.com/read/28484503/quantitative-evaluation-of-chinese-herb-medicine-in-the-treatment-of-sialorrhea-and-frequent-nighttime-urination-in-patients-with-parkinson-s-disease
#17
Chuanhe Sun, Dandan Wang, Wenfei Jiang, Weilong Liao, Penglin Gao, Weidong Pan, Te Liu
Aims. To evaluate the efficacy of Lian-Se formula (LSF), one Chinese herb formulation for treating sialorrhea and frequent overnight urination in patients with Parkinson's disease (PD). Methods. 96 PD patients suffering from sialorrhea and/or frequent nighttime urination were divided into two groups: an LSF group (n = 48) treated with LSF for 6 weeks and a placebo group (n = 48) treated with a placebo formula whose appearance and taste were the same as LSF for 6 weeks. All patients were treated by standard antiparkinsonism medicine according to the PD guideline of China...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28484391/quantitative-evaluation-of-the-compatibility-effects-of-huangqin-decoction-on-the-treatment-of-irinotecan-induced-gastrointestinal-toxicity-using-untargeted-metabolomics
#18
Dong-Ni Cui, Xu Wang, Jia-Qing Chen, Bo Lv, Pei Zhang, Wei Zhang, Zun-Jian Zhang, Feng-Guo Xu
Huangqin decoction (HQD), a traditional Chinese medicine (TCM), has been widely used to treat gastrointestinal syndrome in China for thousands of years. Chemotherapy drug irinotecan (CPT-11) is used clinically to treat various kinds of cancers but limited by its side effects, especially delayed diarrhea. Nowadays, HQD has been proved to be effective in attenuating the intestinal toxicity induced by CPT-11. HQD consists of four medicinal herbs including Scutellaria baicalensis Georgi, Glycyrrhiza uralensis Fisch, Paeonia lactiflora Pall, and Ziziphus jujuba Mill...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28473709/a-new-strategy-for-deleting-animal-drugs-from-traditional-chinese-medicines-based-on-modified-yimusake-formula
#19
Jinghui Wang, Yan Li, Yinfeng Yang, Xuetong Chen, Jian Du, Qiusheng Zheng, Zongsuo Liang, Yonghua Wang
Traditional Chinese medicine (TCM), such as Uyghur Medicine (UM) has been used in clinical treatment for many years. TCM is featured as multiple targets and complex mechanisms of action, which is normally a combination of medicinal herbs and sometimes even contains certain rare animal medicinal ingredients. A question arises as to whether these animal materials can be removed replaced from TCM applications due to their valuable rare resources or animal ethics. Here, we select a classical UM Yimusake formula, which contains 3 animal drugs and other 8 herbs, and has got wealthy experience and remarkable achievements in treating erectile dysfunction (ED) in China...
May 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28408747/alice-bob-physics-coherent-solutions-of-nonlocal-kdv-systems
#20
S Y Lou, Fei Huang
In natural and social science, many events happened at different space-times may be closely correlated. Two events, A (Alice) and B (Bob) are defined correlated if one event is determined by another, say, [Formula: see text] for suitable [Formula: see text] operators. Taking KdV and coupled KdV systems as examples, we can find some types of models (AB-KdV systems) to exhibit the existence on the correlated solutions linked with two events. The idea of this report is valid not only for physical problems related to KdV systems but also for problems described by arbitrary continuous or discrete models...
April 13, 2017: Scientific Reports
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