Alexander V Sorokin, Christin G Hong, Angel M Aponte, Elizabeth M Florida, Jingrong Tang, Nidhi Patel, Irina N Baranova, Haiou Li, Philip M Parel, Vicky Chen, Sierra R Wilson, Emily L Ongstad, Anna Collén, Martin P Playford, Thomas L Eggerman, Marcus Y Chen, Kazuhiko Kotani, Alexander V Bocharov, Alan T Remaley
BACKGROUND: Oxidized ApoB (oxLDL) and other oxidation-modified lipoproteins (OMLs), such as oxidized ApoA-I (oxHDL), are known pro-atherogenic factors. However, OMLs prognostic value for assessing high-risk coronary plaques by coronary computed tomography angiography (CCTA) has not been fully evaluated. METHODS: In a prospective, observational study, 306 participants with known cardiovascular disease (CVD) had extensive lipoprotein profiling, including plasma OMLs and HDL function measured...
September 12, 2023: JCI Insight