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bladder incontinence

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https://www.readbyqxmd.com/read/28093307/the-impact-of-baseline-functional-bladder-capacity-on-short-term-neuromodulation-outcomes
#1
Kim A Killinger, Priyanka Gupta, Jason P Gilleran, Jamie Bartley, Michael Ehlert, Judith A Boura, Kenneth M Peters
OBJECTIVES: To evaluate the impact of functional bladder capacity (FBC) on clinical outcomes after a staged neuromodulation procedure. METHODS: Adults in our prospective neuromodulation database were evaluated. Data were collected from medical records, voiding diaries (FBC defined as average volume per void), Interstitial Cystitis Symptom/Problem Indices (ICSI-PI), Overactive Bladder Questionnaires (OAB-q), and Global Response Assessments over 3 months. Descriptive statistics, Pearson's Chi-square tests, Wilcoxon rank sum tests, logistic regression, repeated measures analyses and Spearman Correlation Coefficients were performed...
January 13, 2017: Urology
https://www.readbyqxmd.com/read/28089812/clinical-manifestations-and-outcomes-in-surgically-managed-gartner-duct-cysts-1
#2
Adela G Cope, Shannon Laughlin-Tommaso, Abimbola Famuyide, John B Gebhart, Matthew R Hopkins, Daniel M Breitkopf
STUDY OBJECTIVE: Gartner duct cysts (GDC) are rare embryological remnants of the mesonephric duct with the majority of cases discovered incidentally in asymptomatic patients. The largest prior published series evaluating surgical management of GDC included 4 patients. The present study aims to determine the manifestations and outcomes of surgically managed patients with GDC with important implications for surveillance, monitoring, and management of patients. DESIGN: Retrospective chart review DESIGN: Classification: Canadian Task Force Classification III SETTING: Tertiary care center PATIENTS: All women diagnosed with GDC from 1/1994-4/2014 at our institution were identified...
January 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28089729/urinary-biomarkers-in-women-with-refractory-urgency-urinary-incontinence-randomized-to-sacral-neuromodulation-versus-onabotulinumtoxina-compared-to-controls
#3
Holly E Richter, Pamela Moalli, Cindy L Amundsen, Anna P Malykhina, Dennis Wallace, Rebecca Rogers, Deborah Myers, Maria Paraiso, Michael Albo, Haolin Shi, Tracy Nolen, Susie Meikle, R Ann Word
PURPOSE: To measure urinary biomarker levels in women with refractory urgency urinary incontinence (UUI) and controls at baseline and 6 months post treatment from sacral neuromodulation (SNM) or intradetrusor injection onabotulinumtoxinA and to assess association of baseline biomarkers to post treatment UUI episodes (UUIE) and overactive bladder (OAB) symptom bother outcomes. MATERIALS AND METHODS: First morning urines were collected from consented trial participants and age-matched women without UUI...
January 13, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28089606/parasacral-transcutaneous-electrical-neural-stimulation-ptens-once-a-week-for-the-treatment-of-overactive-bladder-in-children-a-randomized-controlled-trial
#4
Lidyanne Ilidia da Silva de Paula, Liliana Fajardo de Oliveira, Brysa Paiva Cruz, Dayana Maria de Oliveira, Laís Maini Miranda, Mauro de Moraes Ribeiro, Raphaela Ornellas Duque, André Avarese de Figueiredo, José de Bessa, José Murillo Bastos Netto
INTRODUCTION: Overactive bladder (OAB) is the most prevalent voiding disorder in childhood, and its main manifestation is urinary urgency. In general, urotherapy and anticholinergics are the first choices of treatment. Parasacral Transcutaneous Electrical Neural Stimulation (PTENS) was introduced as an alternative for the treatment of detrusor overactivity in children, but treatment protocols described to date require several sessions per week or long-lasting sessions, making it difficult for the child to adhere to the treatment...
December 21, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28081479/5-year-experience-in-the-diagnosis-and-treatment-of-occult-urinary-incontinence-in-women-with-pelvic-organ-prolapse
#5
Burcin Karamustafaoglu Balci, Funda Gungor Ugurlucan, Cenk Yasa, Onay Yalcin
OBJECTIVE: Our aim was to analyze our five-year experience in the diagnosis and treatment of occult urinary incontinence in women with pelvic organ prolapse. STUDY DESIGN: The medical records of all patients who were admitted to the Division of Urogynecology of Istanbul Faculty of Medicine between January 2008 and December 2013; in total, 1600 patients were retrospectively evaluated. The study population included 287 patients who had prolapse beyond the hymen and underwent two consecutive urodynamic studies with and without prolapse reduction...
January 5, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28077116/quality-of-life-and-functional-outcome-after-infravesical-desobstruction-and-hifu-treatment-for-localized-prostate-cancer
#6
G Hatiboglu, I V Popeneciu, M Deppert, J Nyarangi-Dix, B Hadaschik, M Hohenfellner, D Teber, S Pahernik
BACKGROUND: To evaluate quality of life, functional and oncological outcome after infravesical desobstruction and HIFU treatment for localized prostate cancer. METHODS: One hundred thirty-one patients, treated with TURP and HIFU in a single institution were followed up for oncological and functional outcome. Oncological outcome was quantified by biochemical recurrence free survival using the Stuttgart and Phoenix criteria. Quality of life was assessed by usage of standardized QLQ-C30 and QLQ-PR25 questionnaires...
January 11, 2017: BMC Urology
https://www.readbyqxmd.com/read/28068247/modeling-urinary-dysfunction-after-external-beam-radiation-therapy-of-the-prostate-using-bladder-dose-surface-maps-evidence-of-spatially-variable-response-of-the-bladder-surface
#7
Noorazrul Yahya, Martin A Ebert, Michael J House, Angel Kennedy, John Matthews, David J Joseph, James W Denham
PURPOSE: We assessed the association of the spatial distribution of dose to the bladder surface, described using dose-surface maps, with the risk of urinary dysfunction. METHODS AND MATERIALS: The bladder dose-surface maps of 754 participants from the TROG 03.04-RADAR trial were generated from the volumetric data by virtually cutting the bladder at the sagittal slice, intersecting the bladder center-of-mass through to the bladder posterior and projecting the dose information on a 2-dimensional plane...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28063191/salvage-high-intensity-focused-ultrasound-hifu-for-locally-recurrent-prostate-cancer-after-failed-radiation-therapy-multi-institutional-analysis-of-418-patients
#8
Sebastien Crouzet, Andreas Blana, Francois J Murat, Gilles Pasticier, Stephen C W Brown, Giario N Conti, Roman Ganzer, Olivier Chapet, Albert Gelet, Christian G Chaussy, Cary N Robertson, Stefan Thuroff, John F Ward
OBJECTIVE: To report the oncological outcome of Salvage high-intensity focused ultrasound (S-HIFU) for locally recurrent prostate cancer (PCa) following External Beam Radiotherapy (EBRT) from a multicenter database. MATERIALS AND METHODS: This retrospective study comprises patients from 9 centers with local recurrent disease following EBRT treated with S-HIFU from 1995 to 2009. Biochemical free survival rates (BFSR) was based on the "Phoenix" definition (nadir+2)...
January 7, 2017: BJU International
https://www.readbyqxmd.com/read/28060912/early-fesoterodine-fumarate-administration-prevents-neurogenic-detrusor-overactivity-in-a-spinal-cord-transected-rat-model
#9
Xavier Biardeau, Mikolaj Przydacz, Shachar Aharony, George Loutochin, Lysanne Campeau, Maeva Kyheng, Jacques Corcos
BACKGROUND: In spinal cord injury, onset of detrusor overactivity (DO) is detrimental for quality of life (incontinence) and renal risk. Prevention has only been achieved with complex sophisticated electrical neuromodulation techniques. PURPOSE: To assess the efficacy of early fesoterodine fumarate (FF) administration in preventing bladder overactivity in a spinal cord transected (SCT) rat model. METHODS: 33 Sprague-Dawley rats were allocated to 6 groups-Group 1: 3 normal controls; Group 2: 6 SCT controls; Group 3: 6 SCT rats + FF 0...
2017: PloS One
https://www.readbyqxmd.com/read/28060842/suburothelial-bladder-contraction-detection-with-implanted-pressure-sensor
#10
Steve J A Majerus, Paul C Fletter, Elizabeth K Ferry, Hui Zhu, Kenneth J Gustafson, Margot S Damaser
AIMS: Managing bladder pressure in patients with neurogenic bladders is needed to improve rehabilitation options, avoid upper tract damage, incontinence, and their associated co-morbidities and mortality. Current methods of determining bladder contractions are not amenable to chronic or ambulatory settings. In this study we evaluated detection of bladder contractions using a novel piezoelectric catheter-free pressure sensor placed in a suburothelial bladder location in animals. METHODS: Wired prototypes of the pressure monitor were implanted into 2 nonsurvival (feline and canine) and one 13-day survival (canine) animal...
2017: PloS One
https://www.readbyqxmd.com/read/28053897/effects-of-a-supplement-combining-pycnogenol-%C3%A2-and-l-arginine-aspartate-on-lower-urinary-dysfunction-compared-with-saw-palmetto-extract
#11
Hiroshi Yagi, Ryo Sato, Kojiro Nishio, Gaku Arai, Shigehiro Soh, Hiroshi Okada
OBJECTIVES: Lower urinary tract symptoms (LUTS) and sexual dysfunction (SDys) are common problems that affect quality of life (QOL) in elderly men. In addition to prescribed drugs, many over-the-counter medications including supplements are used to treat QOL diseases. Phosphodiesterase inhibitors are reported to be effective for both LUTS and SDys by increasing nitric oxide levels. French maritime pine bark extract Pycnogenol(®), which is a potent nitric oxide donor, is reported to be effective for SDys...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28052873/path-of-translational-discovery-of-urological-complications-of-obesity-and-diabetes-ucod
#12
Firouz Daneshgari, Guiming Liu, Ann T Hanna-Mitchell
Diabetes Mellitus (DM) is a prevalent chronic disease. Type 1 diabetes mellitus (T1DM) is a metabolic disorder that is characterized by hyperglycemia in the context of absolute lack of insulin; whereas type 2 diabetes mellitus (T2DM) is due to insulin resistance-related relative insulin deficiency. Obesity is an established risk factor for T2DM. In comparison with T1DM, T2DM is more complex. The natural history of T2DM in most patients typically involves a course of obesity to impaired glucose tolerance, to insulin resistance and hyperglycemia...
January 4, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28049246/efficacy-and-tolerability-of-solifenacin-5-mg-fixed-dose-in-korean-children-with-newly-diagnosed-idiopathic-overactive-bladder-a-multicenter-prospective-study
#13
Sang Don Lee, Jae Min Chung, Dong Il Kang, Dong Soo Ryu, Won Yeol Cho, Sungchan Park
We investigated the efficacy and tolerability of solifenacin 5 mg fixed dose in children with newly diagnosed idiopathic overactive bladder (OAB). A total of 34 children (male/female patients = 16/18) aged under 13 years (mean age: 7.2 ± 2.3; range: 5-12) who were newly diagnosed with OAB from January 2012 to September 2014 were prospectively evaluated with open-label protocol. All patients were treated with solifenacin 5 mg fixed dose once daily for at least 4 weeks. The efficacy and tolerability of solifenacin were evaluated 4, 8, and 12 weeks after the initiation of treatment...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28049010/a-rct-to-compare-two-scalable-interventions-for-luts-prevention-main-outcomes-of-the-tulip-study
#14
Carolyn M Sampselle, Diane K Newman, Janis M Miller, Keri Kirk, Mary Ann DiCamillo, Todd H Wagner, Trivellor E Raghunathan, Ananias C Diokno
PURPOSE: To compare two-year urinary incontinence (UI) and urgency scores of older women who attended a two-hour bladder health class (2hrClass) versus those who viewed a 20-minute abbreviated class video (20minVideo) for the purpose of UI prevention. MATERIALS AND METHODS: A randomized, two-arm, parallel design tested the superiority of the 20minVideo over the 24hClass. Outcomes were scores on the International Consultation on Incontinence Short Form (questions 1-3) (ICIQ-SF) (primary outcome) and the Indevus Urgency Severity Scale (IUSS) at baseline, 3-, 12-, and 24-months...
December 31, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28047756/we-ab-207b-09-margin-reduction-for-planning-target-volume-ptv-in-patients-with-localized-prostate-cancer-impact-on-delivered-dose-and-quality-of-life
#15
A Kumarasiri, C Liu, S Brown, C Glide-Hurst, M Elshaikh, I Chetty, B Movsas
PURPOSE: To estimate the delivered (cumulative) dose to targets and organs at risk for localized prostate cancer patients treated with reduced PTV margins and to evaluate preliminary patient reported quality-of-life (QOL). METHODS: Under an IRB-approved protocol, 20 prostate cancer patients (including 11 control patients) were treated with reduced planning margins (5 mm uniform with 4 mm at prostate/rectum interface). Control patients had standard margin (10/6 mm)-based treatments...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047094/we-ab-202-10-modelling-individual-tumor-specific-control-probability-for-hypoxia-in-rectal-cancer
#16
S Warren, D R Warren, J M Wilson, R Muirhead, M A Hawkins, T Maughan, M Partridge
PURPOSE: To investigate hypoxia-guided dose-boosting for increased tumour control and improved normal tissue sparing using FMISO-PET images METHODS: Individual tumor-specific control probability (iTSCP) was calculated using a modified linear-quadratic model with rectal-specific radiosensitivity parameters for three limiting-case assumptions of the hypoxia / FMISO uptake relationship. (18) FMISO-PET images from 2 patients (T3N0M0) from the RHYTHM trial (Investigating Hypoxia in Rectal Tumours NCT02157246) were chosen to delineate a hypoxic region (GTV_MISO defined as tumor-to-muscle ratio > 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044238/vaporize-anatomically-vaporize-or-enucleate-the-prostate-the-flexible-use-of-the-greenlight-laser
#17
Luca Cindolo, Lorenzo Ruggera, Paolo Destefanis, Claudio Dadone, Giovanni Ferrari
PURPOSES: GreenLight laser has gained increasing acceptance as a less invasive treatment for lower urinary tract symptoms due to benign prostatic hyperplasia (BPH/LUTS). Three surgical options were developed: standard photovaporization (PVP), anatomical PVP and GreenLight enucleation of prostate (GreenLEP); however, literature lacks a direct comparison among the procedures. Aim of the present study is to compare the three techniques in a multicentre series of patients. METHODS: Data were collected from consecutive patients with indication to surgical management of BPH/LUTS in five institutions...
January 2, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28043108/the-prevalence-of-nocturia-and-nocturnal-polyuria-can-new-cutoff-values-be-suggested-according-to-age-and-sex
#18
Ali Ersin Zumrutbas, Ali Ihsan Bozkurt, Okan Alkis, Cihan Toktas, Bulent Cetinel, Zafer Aybek
PURPOSE: The aims of this study were to assess the prevalence of nocturia and nocturnal polyuria (NP) and to define new cutoff values according to age and sex for both conditions. METHODS: Data from a population-based prevalence survey conducted among a random sample of 2,128 adults were analyzed in this study. Participants were requested to fill out a questionnaire including the International Continence Society (ICS) definitions of lower urinary tract symptoms and the International Consultation on Incontinence Questionnaire - Short Form...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28042624/literature-review-of-factors-affecting-continence-after-radical-prostatectomy
#19
Dalibor Pacik, Michal Fedorko
Radical prostatectomy (RP) is the most common cause of stress urinary incontinence (UI) in men. Several anatomic structures affect or may affect urinary continence - urethral sphincter, levator ani muscle, puboprostatic ligaments, bladder neck, endopelvic fascia, neurovascular bundle - and understanding of the anatomy of pelvic floor and urethra is crucial for satisfactory functional outcome of the procedure. Surgical techniques implemented to improve continence rates include nerve-sparing procedure, bladder neck preservation/plication, urethral length preservation, musculofascial reconstruction, puboprostatic ligaments preservation or seminal vesicle preservation...
January 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28042169/the-problem-of-polypharmacy-in-female-patients-with-overactive-bladders-cross-sectional-study-in-a-specialist-outpatient-department
#20
C S Schneidinger, W Umek, B Böhmdorfer
Background: The consumption of certain drugs can cause urinary incontinence. The aim of this study is to determine the frequency of consumption of drugs that can favour incontinence, the incidence of polypharmacy and the incidence of potentially dangerous drug-drug interactions in female patients suffering from overactive bladder (OAB) who presented to a urogynaecological outpatient department. Methods: We undertook a retrospective case series study. The data from 100 female patients who attended the urogynaecological outpatient department of the Vienna General Hospital [VGH; Allgemeinen Krankenhauses Wien (AKH)] in the period from 20...
December 2016: Geburtshilfe und Frauenheilkunde
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