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Therapeutic colonoscopy

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https://www.readbyqxmd.com/read/29780594/role-of-endoscopy-in-inflammatory-bowel-disease
#1
REVIEW
Shishira Bharadwaj, Neeraj Narula, Parul Tandon, Mohammad Yaghoobi
Crohn's disease (CD) and ulcerative colitis (UC) constitute the two most common phenotypes of inflammatory bowel disease (IBD). Ileocolonoscopy with biopsy has been considered the gold standard for the diagnosis of IBD. Differential diagnosis of CD and UC is important, as their medical and surgical treatment modalities and prognoses can be different. However, approximately 15% of patients with IBD are misdiagnosed as IBD unclassified due to the lack of diagnostic certainty of CD or UC. Recently, there has been increased recognition of the role of the therapeutic endoscopist in the field of IBD...
May 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29756117/endoscopic-repair-of-rectal-perforation-due-to-colonoscopy-with-a-clamp-method
#2
Osman Köneş, Cevher Akarsu, Tarık Acar, Halil Alış
Colon perforation during colonoscopy is a rare complication that usually requires surgical intervention. Traditionally, primary repair by laparoscopy, laparotomy, resection, and anastomosis is performed for such perforations. More recently developed minimally invasive endoscopic instruments have also been used in the repair of these perforations; this is becoming increasingly common. An endoscopic over-the-scope clip clamp was used in a 59-year-old male patient who suffered a rectum perforation in connection with a diagnostic colonoscopy...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29756019/size-of-colorectal-polyps-determines-time-taken-to-remove-them-endoscopically
#3
Heechan Kang, Mo Hameed Thoufeeq
Background an study aims:  Polypectomy and endoscopic mucosal resection (EMR) are effective and safe ways of removing polyps from the colon at endoscopy. Guidelines exist for advising the time allocation for diagnostic endoscopy but not for polypectomy and EMR. The aim of this study was to identify if time allocated for polypectomy and EMR at planned therapeutic lists in our endoscopy unit is sufficient for procedures to be carried out. We also wanted to identify factors that might be associated with procedures taking longer than the allocated time and to identify factors that might predict duration of these procedures...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29746341/screening-endoscopy-contributes-to-relevant-modifications-of-therapeutic-regimen-in-children-with-intestinal-failure
#4
Andreas Busch, Ekkehard Sturm
OBJECTIVE: The role of endoscopy in the diagnostic work-up of children with intestinal failure (IF) is not well defined. It is unclear whether endoscopies should be performed as a screening procedure or only upon manifestation of symptoms. The aim of this study is to evaluate, whether performing screening endoscopy contributes to clinical management in children with IF. METHODS: Comparative retrospective case-series study in children with IF (mean age 70,4 months ± 58,4 months) presenting for diagnostic work-up in a single intestinal rehabilitation center...
May 9, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29718327/association-between-serum-infliximab-trough-concentrations-during-maintenance-therapy-and-biochemical-endoscopic-and-histologic-remission-in-crohn-s-disease
#5
Konstantinos Papamichael, Shana Rakowsky, Claudio Rivera, Adam S Cheifetz, Mark T Osterman
Background and aim: Objective and more rigorous therapeutic outcomes are emerging as novel targets in Crohn's disease (CD). We investigated the association between maintenance serum infliximab trough concentrations and biochemical, endoscopic, or histologic remission in CD. Methods: This retrospective multicenter study involved consecutive CD patients treated with infliximab who had a serum C-reactive protein (CRP) measured within 1 week or endoscopic evaluation within 12 weeks of therapeutic drug monitoring between January 2010 and June 2016...
April 28, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29666722/postmenopausal-deep-infiltrating-endometriosis-of-the-colon-rare-location-and-novel-medical-therapy
#6
Benjamin M Snyder, Joseph W Beets, Bruce A Lessey, Samuel R W Horton, Gary A Abrams
We report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with no cases distinctly reported in the literature. Additionally, the presentation of gastrointestinal endometriosis as iron deficiency anemia is not well documented in the literature. Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29644509/applications-of-colon-capsule-endoscopy
#7
REVIEW
Shabana F Pasha
PURPOSE OF REVIEW: This is a review of colon capsule endoscopy (CCE) with a focus on its recent developments, technological improvements, and current and potential future indications. RECENT FINDINGS: Based on the current literature, CCE II demonstrates comparable polyp detection rates as optical colonoscopy and CT colonography, and improved cost-effectiveness. The main limitation to patient acceptance is the requirement of a rigorous bowel preparation. Preliminary studies show good correlation between CCE and optical colonoscopy for assessment of colonic disease activity in inflammatory bowel disease (IBD)...
April 12, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29618177/pediatric-colonoscopy-the-changing-patterns-and-single-institutional-experience-over-a-decade
#8
REVIEW
Jae Hong Park
The safety and effectiveness of pediatric colonoscopy for lower gastrointestinal tract diseases have been established in Korea for about 30 years. Both diagnostic and therapeutic colonoscopies have had many advances in terms of operator skill and experience and are now being performed by most pediatric gastroenterologists. Pediatric colonoscopy is different in many aspects from that of adults, such as expected diagnoses, patient management, bowel preparation, selection criteria for sedation, and instrument selection...
March 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/29614542/-gastrointestinal-bleeding-update
#9
Jonel Trebicka, Martin Götz
PREENDOSCOPIC MANAGEMENT:  In suspected gastrointestinal bleeding (GIB), standard operating procedures help in risk stratification, early patient management and endoscopy. If variceal bleeding is suspected, specific medication (vasoconstrictors, antimicrobial therapy) are additive to standard pharmacological management (PPI, erythromycin) prior to endoscopy. COAGULATION REQUIRMENTS:  An emergency endoscopy can be performed independent of the patient's current coagulation status...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29593864/laparoscopic-abdominoperineal-resection-for-the-treatment-of-a-mucinous-adenocarcinoma-associated-with-an-anal-fistula
#10
Dimosthenis Chrysikos, Theodoros Mariolis-Sapsakos, Tania Triantafyllou, Vasileios Karampelias, Apostolos Mitrousias, George Theodoropoulos
Mucinous adenocarcinoma associated with an anal fistula is a rare oncologic entity which may pose diagnostic and therapeutic challenges for Surgeons and Medical Oncologists. Few reported cases without definite therapeutic guidelines exist. It represents 2-3% of all gastrointestinal malignancies and arises from chronic anal fistulas, ischiorectal or perianal abscesses. We report a case of perianal mucinous adenocarcinoma in a 65-year-old male initially surgically treated multiple times for a recurrent fistula in ano of 5 years duration...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29590669/colonoscopic-perforations-in-the-english-national-health-service-bowel-cancer-screening-programme
#11
Edmund Derbyshire, Pali Hungin, Claire Nickerson, Matthew D Rutter
BACKGROUND: Perforation is the most serious adverse event associated with colonoscopy. In this study of data from the English National Health Service Bowel Cancer Screening Programme, we aimed to describe the presentation and management of perforations, and to determine factors associated with poorer outcomes post-perforation. METHODS: The medical records of patients with a perforation following the national screening colonoscopy were retrospectively examined. All colonoscopies performed from 02/08/2006 to 13/03/2014 were studied...
March 28, 2018: Endoscopy
https://www.readbyqxmd.com/read/29570555/single-balloon-assisted-colonoscopy-for-placement-of-colonic-manometry-catheters-initial-experience-in-children
#12
Rinarani M Sanghavi, Ricardo Medina-Centeno, Bradley Barth
OBJECTIVES: Colonic manometry is used frequently in children with long standing and difficult to manage constipation to aid in management decisions. Accurate analysis requires placement of the colonic manometry catheter in the colon without looping. This is technically difficult due to the long-standing nature of the constipation in most patients leading to sigmoid and other colonic redundancy. Single balloon colonoscopy has been successfully used in adult in cases of difficult colonoscopy...
March 22, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29531307/mucosal-luminal-interface-proteomics-reveals-biomarkers-of-pediatric-inflammatory-bowel-disease-associated-colitis
#13
Shelley A Deeke, Amanda E Starr, Zhibin Ning, Sara Ahmadi, Xu Zhang, Janice Mayne, Cheng-Kang Chiang, Ruth Singleton, Eric I Benchimol, David R Mack, Alain Stintzi, Daniel Figeys
OBJECTIVE: Improved biomarkers are an unmet clinical need for suspected inflammatory bowel disease (IBD). Need is greatest for children, since current biomarkers suffers from low specificity, particularly in this population; thus, invasive testing methods, with the accompanying risk of complications, are necessary. Additionally, current biomarkers do not delineate disease extent assessment for ulcerative colitis (UC), a factor involved in therapeutic decisions. METHODS: Intestinal mucosal-luminal interface (MLI) aspirates from the ascending colon (AC) and descending colon (DC) were collected during diagnostic colonoscopy from treatment-naïve children...
March 12, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29514146/multiparametric-evaluation-predicts-different-mid-term-outcomes-in-crohn-s-disease
#14
Lucrezia Laterza, Anna Chiara Piscaglia, Laura Maria Minordi, Iolanda Scoleri, Luigi Larosa, Andrea Poscia, Fabio Ingravalle, Arianna Amato, Sergio Alfieri, Alessandro Armuzzi, Giovanni Cammarota, Antonio Gasbarrini, Franco Scaldaferri
AIM: To evaluate if a single and/or combined (clinical, endoscopic and radiological) assessment could predict clinical outcomes in Crohn's disease (CD). METHODS: We prospectively evaluated 57 CD cases who underwent both a colonoscopy and a CT-enterography (CTE). Harvey-Bradshaw Index (HBi), SES-CD (and/or Rutgeerts score) and the radiological disease activity were defined to stratify patients according to clinical, endoscopic and radiological disease activity respectively...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29469316/-clinical-features-of-imported-schistosomiasis-mansoni-in-beijing-city%C3%AF-a-report-of-6-cases
#15
Zou Yang, Wang Lei, Li Xiao-Li, Tian Xiao-Jun, Li Wei, An Yi-Jun, Qi Zhi-Qun, Li Jing-Jing, Wang Fei, Huang Min-Jun
OBJECTIVE: To analyze the clinical features of 6 patients with imported schistosomiasis mansoni, including the epidemic history, clinical manifestations, laboratory tests and therapeutic effect, so as to provide references for improving the levels of diagnosis and treatment of physicians. METHODS: The clinical data of 6 patients with imported schistosomiasis mansoni from January 2009 to July 2016 were collected and analyzed. RESULTS: All the 6 imported patients with schistosomiasis mansoni had a clear history of cercarial infested water exposure...
March 10, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29459013/the-family-coriobacteriaceae-is-a-potential-contributor-to-the-beneficial-effects-of-roux-en-y-gastric-bypass-on-type-2-diabetes
#16
Haijun Liu, Hong Zhang, Xiao Wang, Xuemei Yu, Cheng Hu, Xueli Zhang
BACKGROUND: Changes in gut microbiota induced by bariatric surgery have been associated with metabolic benefits. OBJECTIVES: Our aim was to identify specific gut microbiota that may contribute to the improvement of type 2 diabetes (T2D) after Roux-en-Y gastric bypass (RYGB). SETTING: Laboratories of Shanghai Diabetes Institute and Shanghai Sixth People's Hospital. METHODS: Diabetic rats induced via a high-fat diet and low-dose streptozotocin administration were randomized to RYGB or sham surgery, and stool samples were collected at baseline and at postoperative week 8...
January 17, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29423432/complications-and-outcomes-of-routine-endoscopy-in-the-very-elderly
#17
Ryoichi Miyanaga, Naoki Hosoe, Makoto Naganuma, Kenro Hirata, Seiichiro Fukuhara, Yoshihiro Nakazato, Keisuke Ojiro, Eisuke Iwasaki, Naohisa Yahagi, Haruhiko Ogata, Takanori Kanai
Background and study aims:  In Japan, the elderly population has been increasing annually. The number of elderly patients for whom esophagogastroduodenoscopy (EGD) and colonoscopy (CS) is indicated also has been rising. The aim of this study was to evaluate the safety and efficacy of routine endoscopy in a cohort of octogenarians aged 85 years and older - defined by the World Health Organization as the very elderly. Patients and methods:  A total of 5,586 patients underwent EGDs, and 2,484 patients underwent CSs performed at the Keio University Hospital from January to September 2014...
February 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29416554/2017-wses-guidelines-for-the-management-of-iatrogenic-colonoscopy-perforation
#18
REVIEW
Nicola de'Angelis, Salomone Di Saverio, Osvaldo Chiara, Massimo Sartelli, Aleix Martínez-Pérez, Franca Patrizi, Dieter G Weber, Luca Ansaloni, Walter Biffl, Offir Ben-Ishay, Miklosh Bala, Francesco Brunetti, Federica Gaiani, Solafah Abdalla, Aurelien Amiot, Hany Bahouth, Giorgio Bianchi, Daniel Casanova, Federico Coccolini, Raul Coimbra, Gian Luigi de'Angelis, Belinda De Simone, Gustavo P Fraga, Pietro Genova, Rao Ivatury, Jeffry L Kashuk, Andrew W Kirkpatrick, Yann Le Baleur, Fernando Machado, Gustavo M Machain, Ronald V Maier, Alain Chichom-Mefire, Riccardo Memeo, Carlos Mesquita, Juan Carlos Salamea Molina, Massimiliano Mutignani, Ramiro Manzano-Núñez, Carlos Ordoñez, Andrew B Peitzman, Bruno M Pereira, Edoardo Picetti, Michele Pisano, Juan Carlos Puyana, Sandro Rizoli, Mohammed Siddiqui, Iradj Sobhani, Richard P Ten Broek, Luigi Zorcolo, Maria Clotilde Carra, Yoram Kluger, Fausto Catena
Iatrogenic colonoscopy perforation (ICP) is a severe complication that can occur during both diagnostic and therapeutic procedures. Although 45-60% of ICPs are diagnosed by the endoscopist while performing the colonoscopy, many ICPs are not immediately recognized but are instead suspected on the basis of clinical signs and symptoms that occur after the endoscopic procedure. There are three main therapeutic options for ICPs: endoscopic repair, conservative therapy, and surgery. The therapeutic approach must vary based on the setting of the diagnosis (intra- or post-colonoscopy), the type of ICP, the characteristics and general status of the patient, the operator's level of experience, and surgical device availability...
2018: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/29394768/-a-case-report-of-post-radiochemotherapy-perineum-abscess-concurrent-with-recurrence-of-vaginal-cancer-for-which-total-pelvic-exenteration-was-performed
#19
Hiroki Imamura, Kohei Murata, Yoshinori Kagawa, Rieko Okubo, Takuya Sakamoto, Atsushi Naito, Kohei Murakami, Yoshiteru Katsura, Yoshiaki Ohmura, Atsushi Takeno, Shinichi Nakatsuka, Kimihiko Ito, Yutaka Takeda, Takeshi Kato, Shigeyuki Tamura
We report a case of a woman who was suffering from post-radiochemotherapy perineum abscess concurrent with the recurrence of vaginal cancer for which total pelvic exenteration was performed. A 66-year-oldwoman presentedat our hospital with irregular genital bleeding in November 2014. A series of examinations showedthat she was suffering from vaginal cancer(cT2N0M0, cStage II ). A radiochemotherapy regimen(external irradiation 45 Gy/25 Fr, CDDP 40mg/m2, 5 course)was commencedin January 2015. In the meantime, MRI revealedsome therapeutic effect, but in October 2015, MRI indicated the enlargement of the primary tumor(PD)...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29390877/adipose-derived-mesenchymal-stromal-cells-improve-the-healing-of-colonic-anastomoses-following-high-dose-of-irradiation-through-anti-inflammatory-and-angiogenic-processes
#20
Dirk Van de Putte, Christelle Demarquay, Elke Van Daele, Lara Moussa, Christian Vanhove, Marc Benderitter, Wim Ceelen, Piet Pattyn, Noëlle Mathieu
Cancer patients treated with radiotherapy (RT) could develop severe late side effects that affect their quality of life. Long-term bowel complications after RT are mainly characterized by a transmural fibrosis that could lead to intestinal obstruction. Today, surgical resection is the only effective treatment. However, preoperative RT increases the risk of anastomotic leakage. In this study, we attempted to use mesenchymal stromal cells from adipose tissue (Ad-MSCs) to improve colonic anastomosis after high-dose irradiation...
December 2017: Cell Transplantation
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