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normal-pressure hydrocephalus

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https://www.readbyqxmd.com/read/28339331/differential-diagnosis-of-a-patient-referred-to-physical-therapy-for-dizziness-a-case-report
#1
Zachary Rethorn, Susan J Barlow, Emily Gavlick
STUDY DESIGN: Case report. BACKGROUND: Dizziness is a common and debilitating condition across the lifespan. Patients with this complaint must be carefully examined to determine the cause of dizziness, rule out the presence of central nervous system dysfunction, and determine the appropriateness of physical therapy intervention. CASE DESCRIPTION: A 90-year-old male was referred to physical therapy six months after the onset of dizziness. A thorough history was taken and examination was performed...
March 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28331772/an-automated-gravity-driven-csf-drainage-system-decreases-complications-and-lowers-costs
#2
Robert E Lieberson, Jan Eckermann, William Meyer, Tung Trang
BACKGROUND: FlowSafe(TM) (BeckerSmith Medical, Irvine, CA, USA) is a novel, robotic, external lumbar drainage (ELD) system, which was designed to control cerebrospinal fluid (CSF) drainage, reduce complications, and decrease treatment costs. METHODS:  Forty-seven consecutive neurosurgical patients requiring ELD were treated using the FlowSafe system. RESULTS: In 39 of 40 patients with traumatic and surgical dural openings, potential CSF leaks were avoided...
February 3, 2017: Curēus
https://www.readbyqxmd.com/read/28293475/nationwide-hospital-based-survey-of-idiopathic-normal-pressure-hydrocephalus-in-japan-epidemiological-and-clinical-characteristics
#3
Nagato Kuriyama, Masakazu Miyajima, Madoka Nakajima, Michiko Kurosawa, Wakaba Fukushima, Yoshiyuki Watanabe, Etsuko Ozaki, Yoshio Hirota, Akiko Tamakoshi, Etsuro Mori, Takeo Kato, Takahiko Tokuda, Akinori Urae, Hajime Arai
OBJECTIVES: There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus (iNPH) in Japan. Therefore, a nationwide epidemiologic survey of iNPH was performed to determine the number of cases and clinical characteristics by sex and diagnostic level. METHODS: The first survey examined the numbers of cases that met the diagnostic criteria of iNPH and those who underwent shunt operations in 2012. The second survey gathered patients' details to clarify their clinical background characteristics...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28282809/how-i-do-it-clinical-application-of-brain-mri-in-the-diagnostic-work-up-of-parkinsonism
#4
Frederick J A Meijer, Bozena Goraj, Bastiaan R Bloem, Rianne A J Esselink
Differentiating Parkinson's disease and atypical parkinsonism on clinical parameters is challenging, especially in early disease courses. This is due to large overlap in symptoms and because the so called red flags, i.e. symptoms indicating atypical parkinsonism, have not (fully) developed. Brain MRI can aid to improve the accuracy and confidence about the diagnosis. The main purpose of brain MRI is to assess cerebrovascular damage, and to exclude other possible - and sometimes treatable - causes of parkinsonism, such as normal pressure hydrocephalus...
March 6, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28277554/morphological-changes-of-anterior-cerebral-artery-aca-in-hydrocephalic-pediatric-patients
#5
Sait Ozturk, Erdogan Ayan, Metin Kaplan
OBJECTIVE: The morphology of anterior cerebral artery (ACA) in patients with hydrocephalus (HCP) was analyzed, and its importance was discussed in maintaining cerebral perfusion. MATERIALS & METHODS: A total of 84 cases in 2 groups between 0 and 3 months, followed-up at Firat Universitesi Hastanesi, Beyin Cerrahisi Klinigi, Elazig, Turkiye due to in 2010-2013, were enrolled. Two groups were created for the study. Group 1; patients with HCP and Group 2; as control group without HCP...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28259041/trunk-sway-in-idiopathic-normal-pressure-hydrocephalus-quantitative-assessment-in-clinical-practice
#6
Tomas Bäcklund, Jennifer Frankel, Hanna Israelsson, Jan Malm, Nina Sundström
BACKGROUND: In diagnosis and treatment of patients with idiopathic normal pressure hydrocephalus (iNPH), there is need for clinically applicable, quantitative assessment of balance and gait. Using a body-worn gyroscopic system, the aim of this study was to assess postural stability of iNPH patients in standing, walking and during sensory deprivation before and after cerebrospinal fluid (CSF) drainage and surgery. A comparison was performed between healthy elderly (HE) and patients with various types of hydrocephalus (ventriculomegaly (VM))...
February 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28257339/symri-of-the-brain-rapid-quantification-of-relaxation-rates-and-proton-density-with-synthetic-mri-automatic-brain-segmentation-and-myelin-measurement
#7
Akifumi Hagiwara, Marcel Warntjes, Masaaki Hori, Christina Andica, Misaki Nakazawa, Kanako Kunishima Kumamaru, Osamu Abe, Shigeki Aoki
Conventional magnetic resonance images are usually evaluated using the image signal contrast between tissues and not based on their absolute signal intensities. Quantification of tissue parameters, such as relaxation rates and proton density, would provide an absolute scale; however, these methods have mainly been performed in a research setting. The development of rapid quantification, with scan times in the order of 6 minutes for full head coverage, has provided the prerequisites for clinical use. The aim of this review article was to introduce a specific quantification method and synthesis of contrast-weighted images based on the acquired absolute values, and to present automatic segmentation of brain tissues and measurement of myelin based on the quantitative values, along with application of these techniques to various brain diseases...
March 3, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28251346/cost-effectiveness-analysis-of-shunt-surgery-for-idiopathic-normal-pressure-hydrocephalus-based-on-the-sinphoni-and-sinphoni-2-trials
#8
Masahiro Kameda, Shigeki Yamada, Masamichi Atsuchi, Teruo Kimura, Hiroaki Kazui, Masakazu Miyajima, Etsuro Mori, Masatsune Ishikawa, Isao Date
BACKGROUND: We showed that ventriculoperitoneal (VP) shunt and lumboperitoneal (LP) shunt surgeries are beneficial for patients with idiopathic normal pressure hydrocephalus (iNPH) in the Study of Idiopathic Normal Pressure Hydrocephalus on Neurological Improvement (SINPHONI; a multicenter prospective cohort study) and in SINPHONI-2 (a multicenter randomized trial). Although therapeutic efficacy is important, cost-effectiveness analysis is equally valuable. METHODS: Using both a set of assumptions and using the data from SINPHONI and SINPHONI-2, we estimated the total cost of treatment for iNPH, which consists of medical expenses (e...
March 1, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28247411/reversed-aqueductal-cerebrospinal-fluid-net-flow-in-idiopathic-normal-pressure-hydrocephalus
#9
L K Yin, J J Zheng, L Zhao, X Z Hao, X X Zhang, J Q Tian, K Zheng, Y M Yang
OBJECTIVES: The changes of CSF flow dynamics in idiopathic normal pressure hydrocephalus (iNPH) are not fully elucidated. Most previous studies took the whole cardiac cycle as a unit. In this work, it is divided into systole and diastole phase and compared between iNPH patients and normal elderly and paid special attention to the change of netflow direction. MATERIALS AND METHODS: Twenty iNPH patients according to international guideline and twenty healthy volunteers were included in this study and examined by MRI...
March 1, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28238737/mortality-and-risk-of-dementia-in-normal-pressure-hydrocephalus-a%C3%A2-population-study
#10
Daniel Jaraj, Carsten Wikkelsø, Katrin Rabiei, Thomas Marlow, Christer Jensen, Svante Östling, Ingmar Skoog
INTRODUCTION: We examined mortality, dementia, and progression of hydrocephalic symptoms among untreated individuals with idiopathic normal-pressure hydrocephalus (iNPH) in a population-based sample. METHODS: A total of 1235 persons were examined between 1986 and 2012. Shunted individuals were excluded. We examined 53 persons with hydrocephalic ventricular enlargement (probable iNPH: n = 24, asymptomatic or possible iNPH: n = 29). Comparisons were made with individuals without hydrocephalic ventricular enlargement...
February 24, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28195509/reduced-subarachnoid-fluid-diffusion-in-enlarged-subarachnoid-spaces-of-infancy
#11
Matthew T Whitehead, Bonmyong Lee, Audrey McCarron, Stanley T Fricke, Gilbert Vezina
Background and purpose Enlargement of the subarachnoid spaces in infancy (ESSI) is a common cause of macrocephaly without proven explanation. We have observed subarachnoid diffusion to be decreased in these patients. We aim to quantify the diffusivity of ventricular and subarachnoid cerebrospinal fluid in ESSI patients, to determine if diffusion characteristics deviate from normocephalic infants, and to propose a unique mechanism for ESSI. Materials and methods 227 consecutive brain magnetic resonance exams from different macrocephalic children were retrospectively reviewed after institutional review board waiver...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28185313/improvement-in-lower-urinary-tract-symptoms-across-multiple-domains-following-ventriculoperitoneal-shunting-for-idiopathic-normal-pressure-hydrocephalus
#12
Sarah C Krzastek, Samuel P Robinson, Harold F Young, Adam P Klausner
AIMS: The purpose of this study was to evaluate the change in lower urinary tract symptoms following ventriculoperitoneal shunting in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS: Lower urinary tract symptoms in patients with new-onset iNPH were prospectively evaluated using validated questionnaires from the International Consultation on Incontinence to assess overactive bladder (ICIq-OAB), incontinence (ICIq-UI), and quality of life (ICIq-LUTqol), as well as the American Urological Association Symptom Score bother scale, prior to and following ventriculoperitoneal shunting for iNPH...
February 10, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28156249/utility-of-mri-based-disproportionately-enlarged-subarachnoid-space-hydrocephalus-scoring-for-predicting-prognosis-after-surgery-for-idiopathic-normal-pressure-hydrocephalus-clinical-research
#13
Narihide Shinoda, Osamu Hirai, Shinya Hori, Kazuyuki Mikami, Toshiaki Bando, Daisuke Shimo, Takahiro Kuroyama, Yoji Kuramoto, Masato Matsumoto, Yasushi Ueno
OBJECTIVE The presence of disproportionately enlarged subarachnoid space hydrocephalus (DESH) on brain imaging is a recognized finding of idiopathic normal pressure hydrocephalus (iNPH), but the features of DESH can vary across patients. The aim of this study was to evaluate the utility of MRI-based DESH scoring for predicting prognosis after surgery. METHODS In this single-center, retrospective cohort study, the DESH score was determined by consensus between a group of neurosurgeons, neurologists, and a neuroradiologist based on the preoperative MRI findings of the patients with suspected iNPH...
February 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28140607/phase-contrast-mri-csf-flow-measurements-for-the-diagnosis-of-normal-pressure-hydrocephalus-observer-agreement-of-velocity-versus-volume-parameters
#14
Ahmed Mohamed Tawfik, Lamiaa Elsorogy, Rabab Abdelghaffar, Ayman Abdel Naby, Ibrahim Elmenshawi
OBJECTIVE: Manual segmentation of the aqueduct for CSF flow analysis may induce measurement variability. The aim of our study was to assess observer agreement of manual segmentation and to compare the repeatability and accuracy of different flow parameters in differentiating normal-pressure hydrocephalus (NPH) from brain atrophy. SUBJECTS AND METHODS: Thirty-two subjects were included and were divided into three groups: control, NPH, and brain atrophy. Subjects underwent phase-contrast MRI...
April 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28132644/a-change-in-brain-white-matter-after-shunt-surgery-in-idiopathic-normal-pressure-hydrocephalus-a-tract-based-spatial-statistics-study
#15
Shigenori Kanno, Makoto Saito, Tomohito Kashinoura, Yoshiyuki Nishio, Osamu Iizuka, Hirokazu Kikuchi, Masahito Takagi, Masaki Iwasaki, Shoki Takahashi, Etsuro Mori
BACKGROUND: The aim of this study was to elucidate changes in cerebral white matter after shunt surgery in idiopathic normal pressure hydrocephalus (INPH) using diffusion tensor imaging (DTI). METHODS: Twenty-eight consecutive INPH patients whose symptoms were followed for 1 year after shunt placement and 10 healthy control (HC) subjects were enrolled. Twenty of the initial 28 INPH patients were shunt-responsive (SR) and the other 8 patients were non-responsive (SNR)...
January 30, 2017: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/28127435/dementia-gait-disturbance-and-urinary-incontinence-in-a-patient-with-pulmonary-sarcoidosis
#16
Gonzalo Labarca, Romina Ramirez, Ximena Monsalve, Isabel Mira-Avendano
Hydrocephalus is an uncommon presentation of neurosarcoidosis. We discuss the case of a 67-year-old woman with a prior diagnosis of hypothyroidism, systemic hypertension, and lung sarcoidosis who presented with a 1-month history of progressive impairment of consciousness leading to prostration and loss of sphincter control. At admission, patient was febrile with altered speech and without focalization. Laboratory results showed leucocytosis and mild anaemia. Cerebrospinal fluid (CSF) analysis was characterized by mild elevated protein level, increased cell count, normal glucose and adenosine deaminase (ADA), negative cytology, and no bacterial isolations...
September 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28120085/neuropsychological-assessment-in-the-differential-diagnosis-of-idiopathic-normal-pressure-hydrocephalus-an-important-tool-for-the-maintenance-and-restoration-of-neuronal-and-neuropsychological-functions
#17
Carmela Sindorio, Rosaria Viola Abbritti, Giovanni Raffa, Stefano M Priola, Antonino Germanò, Massimiliano Visocchi, Maria C Quattropani
Idiopathic normal pressure hydrocephalus (iNPH) is a progressive clinical syndrome that includes gait disturbances, urinary incontinence, and cognitive impairment. iNPH shows similarities to other neurodegenerative disorders, primarily Alzheimer's Disease (AD). Definition of the neuropsychological profile of iNPH and the qualitative analysis of systematic mistakes made in cognitive tests could represent a valid method for systematizing possible specific markers of iNPH dementia and differentiating it from other dementias...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28113783/the-role-of-a-dynamic-craniospinal-compliance-in-nph-a-review-and-future-challenges
#18
Christine Goffin, Steffen Leonhardt, Klaus Radermacher
Despite the normal mean intracranial pressure (ICP) in normal pressure hydrocephalus (NPH) the cerebral ventricles enlarge. Many hypotheses exist, which have lately been investigated in simulation. These can be grouped into one of the two categories.
October 24, 2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28089835/supplementary-tests-in-idiopathic-normal-pressure-hydrocephalus-a-single-center-experience-with-a-combined-lumbar-infusion-test-and-tap-test
#19
F Raneri, M A S Zella, A Di Cristofori, B Zarrino, M Pluderi, D Spagnoli
INTRODUCTION: Lumbar infusion test (LIT) and Tap Test (TT) have previously been described for the diagnosis and the selection of appropriate surgical candidates in idiopathic normal pressure hydrocephalus (iNPH) MATERIALS AND METHODS: We retrospectively reviewed 81 consecutive patients with clinical diagnosis of iNPH selected for supplementary testing. Clinical evaluation was scored with the Japanese Grading Scale for Normal Pressure Hydrocephalus (JGSNPH), the Global Deterioration Score (GDS) and the modified Rankin Scale (mRS)...
January 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28089743/multichannel-visual-evoked-potentials-in-the-assessment-of-visual-pathways-in-children-with-marked-brain-abnormalities
#20
Sian E Handley, Alki C Liasis
PURPOSE: To demonstrate how multichannel visual evoked potentials (VEPs) can provide quantitative measures of visual function in children with marked cortical anatomy abnormalities. METHODS: Four children with marked brain pathology (2 holoprosencephaly, 2 giant interhemispheric cysts with hydrocephalus) underwent pattern reversal and flash VEP recordings from 16 equally distributed electrodes. Voltage maps of the major VEP components were constructed, and their distributions were compared to the magnetic resonance imaging (MRI) findings...
January 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
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