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normal-pressure hydrocephalus

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https://www.readbyqxmd.com/read/29026928/-current-treatment-concepts-in-intracerebral-hemorrhage
#1
REVIEW
H B Huttner, J B Kuramatsu
BACKGROUND AND OBJECTIVE: In recent years, various important studies investigating the management of intracerebral hemorrhage (ICH) have been published. However, these have not entered guideline recommendations yet. Therefore, essential results are summarized here and the findings are integrated into current treatment concepts. MATERIALS AND METHODS: Based on a dedicated literature review and the authors' experience, up-to-date and high-quality investigations were identified...
October 12, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29023635/intermittent-gait-disturbance-in-idiopathic-normal-pressure-hydrocephalus
#2
Y Nikaido, Y Kajimoto, A Tucker, K Kuroda, H Ohno, T Akisue, R Saura, T Kuroiwa
OBJECTIVES: We identified intermittent gait disturbance (IGD) observed in the mild stage of idiopathic normal pressure hydrocephalus (iNPH). The first purpose of this study was to clarify the temporal gait profile of IGD during long-distance gait. The second purpose was to confirm the difference in treatment effect after cerebrospinal fluid (CSF) shunting in patients with and without IGD. MATERIALS AND METHODS: Fourteen consecutive iNPH patients with mild gait disturbance with a timed up-and-go (TUG) of <20 seconds were prospectively enrolled in the study...
October 11, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29022960/idiopathic-intracranial-hypertension-in-a-pubertal-paediatric-indian-patient
#3
Anand Aggarwal, Prempal Kaur, Kanika Chhabra, Karamjit Singh, Piyush Goyal
BACKGROUND: Idiopathic Intracranial Hypertension (IIH) is characterised by raised intracranial pressure (ICP) with normal cerebrospinal fluid (CSF) composition and absence of hydrocephalus or space occupying lesions. IIH is a rare disease in children. It can lead to visual impairment but prompt diagnosis and treatment in most of the cases will prevent potentially permanent visual loss. OBJECTIVE: To report a rare case of Idiopathic Intracranial Hypertension in a pubertal child, clinical features, and findings of Magnetic Resonance Imaging (MRI) and visual field of this case...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28993205/a-novel-technology-to-model-pressure-induced-cellular-injuries-in-the-brain
#4
Michael E Smith, Ramin Eskandari
BACKGROUND: Elevated intracranial pressure (ICP) accompanying a number of neurological emergencies is poorly understood, and lacks a model to determine cellular pathophysiology. This limits our ability to identify cellular and molecular biomarkers associated with the pathological progression from physiologic to pathologic ICP. NEW METHOD: We developed an ex vivo model of pressure-induced brain injury, which combines 3D neural cell cultures and a newly developed Pressure Controlled Cell Culture Incubator (PC(3)I)...
October 6, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28991942/confusion-recurs-2-weeks-after-fall
#5
Nick Koneri, Andrew Muck, Bruce D Adams
A 77-year-old woman presented to the emergency department complaining of a headache following a syncopal episode (while standing) earlier that day. She said that she'd lost consciousness for several minutes, and then experienced several minutes of mild confusion that resolved spontaneously. On physical exam, she was oriented to person and place, but not time. She had a contusion in her left occipitoparietal region without extensive bruising or deformity. The patient had normal cardiopulmonary, abdominal, and neurologic exams...
October 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28987681/the-evans-index-revisited-new-cut-off-levels-for-use-in-radiological-assessment-of-ventricular-enlargement-in-the-elderly
#6
Maiken K Brix, Eric Westman, Andrew Simmons, Geir Andre Ringstad, Per Kristian Eide, Kari Wagner-Larsen, Christian M Page, Valeria Vitelli, Mona K Beyer
BACKGROUND AND PURPOSE: Assessment of ventricular enlargement is subjective and based on the radiologist's experience. Linear indices, such as the Evans Index (EI), have been proposed as markers of ventricular volume with an EI≥0.3 indicating pathologic ventricular enlargement in any subject. However, normal range for EI measured on magnetic resonance imaging (MRI) scans are lacking in healthy elderly according to age and sex. We propose new age and sex specific cut-off values for ventricular enlargement in the elderly population...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28987185/cerebrospinal-fluid-circulation-and-hydrocephalus
#7
Ville Leinonen, Ritva Vanninen, Tuomas Rauramaa
Hydrocephalus (HC) is classically defined as dynamic imbalance between the production and absorption of cerebrospinal fluid (CSF) leading to enlarged ventricles. Potential causative factors include various brain disorders like tumors causing obstruction of CSF flow within the ventricular system or the subarachnoid space. Classification of HC is based on the site of CSF flow obstruction guiding optimal treatment, with endoscopic third ventriculostomy in intraventricular obstruction and CSF shunt in communicating HC...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28984604/alzheimer-s-disease-related-polymorphisms-in-shunt-responsive-idiopathic-normal-pressure-hydrocephalus
#8
Joel Huovinen, Seppo Helisalmi, Jussi Paananen, Tiina Laiterä, Maria Kojoukhova, Anna Sutela, Ritva Vanninen, Marjo Laitinen, Tuomas Rauramaa, Anne M Koivisto, Anne M Remes, Hilkka Soininen, Mitja Kurki, Annakaisa Haapasalo, Juha E Jääskeläinen, Mikko Hiltunen, Ville Leinonen
BACKGROUND: Idiopathic normal pressure hydrocephalus (iNPH) is a late onset, surgically treated progressive brain disease caused by impaired cerebrospinal fluid dynamics and subsequent ventriculomegaly. Comorbid Alzheimer's disease (AD) seems to be frequent in iNPH. OBJECTIVE: We aim to evaluate the role of AD-related polymorphisms in iNPH. METHODS: Overall 188 shunt-operated iNPH patients and 688 controls without diagnosed neurodegenerative disease were included into analysis...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28969373/glymphatic-mri-in-idiopathic-normal-pressure-hydrocephalus
#9
Geir Ringstad, Svein Are Sirirud Vatnehol, Per Kristian Eide
The glymphatic system has in previous studies been shown as fundamental to clearance of waste metabolites from the brain interstitial space, and is proposed to be instrumental in normal ageing and brain pathology such as Alzheimer's disease and brain trauma. Assessment of glymphatic function using magnetic resonance imaging with intrathecal contrast agent as a cerebrospinal fluid tracer has so far been limited to rodents. We aimed to image cerebrospinal fluid flow characteristics and glymphatic function in humans, and applied the methodology in a prospective study of 15 idiopathic normal pressure hydrocephalus patients (mean age 71...
October 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28953678/use-of-programmable-versus-nonprogrammable-shunts-in-the-management-of-normal-pressure-hydrocephalus-a-multicenter-retrospective-study-with-cost-benefit-analysis-in-turkey
#10
Yurdal Serarslan, Atilla Yilmaz, Mürteza Çakır, Ebru Güzel, Akin Akakin, Aslan Güzel, Boran Urfalı, Mustafa Aras, Mustafa Emrah Kaya, Nebi Yılmaz
Ventriculoperitoneal shunt systems that are used in the treatment of normal pressure hydrocephalus are often associated with drainage problems. Adjustable shunt systems can prevent or treat these problems, but they may be expensive. The aim of our study is to compare the complications and total cost of several shunt systems.Patients with normal pressure hydrocephalus who underwent ventriculoperitoneal shunting between 2011 and 2016 were included in the study. The study involves patient consent and the informed consent was given...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28947761/human-cerebrospinal-fluid-promotes-long-term-neuronal-viability-and-network-function-in-human-neocortical-organotypic-brain-slice-cultures
#11
Niklas Schwarz, Ulrike B S Hedrich, Hannah Schwarz, Harshad P A, Nele Dammeier, Eva Auffenberg, Francesco Bedogni, Jürgen B Honegger, Holger Lerche, Thomas V Wuttke, Henner Koch
Pathophysiological investigation of CNS-related diseases, such as epilepsy or neurodegenerative disorders, largely relies on histological studies on human post mortem tissue, tissue obtained by biopsy or resective surgery and on studies using disease models including animal models, heterologous expression systems or cell culture based approaches. However, in general it remains elusive to what extent results obtained in model systems can be directly translated to the human brain, calling for strategies allowing validation or even primary investigation in live human CNS tissue...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28943702/efficient-multi-atlas-registration-using-an-intermediate-template-image
#12
Blake E Dewey, Aaron Carass, Ari M Blitz, Jerry L Prince
Multi-atlas label fusion is an accurate but time-consuming method of labeling the human brain. Using an intermediate image as a registration target can allow researchers to reduce time constraints by storing the deformations required of the atlas images. In this paper, we investigate the effect of registration through an intermediate template image on multi-atlas label fusion and propose a novel registration technique to counteract the negative effects of through-template registration. We show that overall computation time can be decreased dramatically with minimal impact on final label accuracy and time can be exchanged for improved results in a predictable manner...
February 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28942232/an-unusual-case-of-temporal-bone-encephalomeningocele-occurring-together-with-normal-pressure-hydrocephalus
#13
Bernard Tan Wen Sheng, David Low Yong Ming, Heng Wai Yuen
Temporal bone encephalomeningoceles are uncommon clinical entities that can be challenging to diagnose and treat. Common presenting complaints include symptoms of aural fullness, hearing loss, clear otorrhea and meningitis. Common etiologies are chronic middle ear disease and trauma. A significant proportion of cases are spontaneous, which occurs in relation to benign intracranial hypertension. Normal pressure hydrocephalus associated with temporal bone encepahomeningoceles has not been previously described...
September 20, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28940258/is-there-even-such-a-thing-as-idiopathic-normal-pressure-hydrocephalus
#14
Clifford B Saper
No abstract text is available yet for this article.
September 21, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28934739/differential-pressure-shunt-for-simultaneous-diversion-of-ventricular-fluid-and-extracerebral-fluid
#15
Daniel Craig, Ken R Winston, Zach Folzenlogen, Kathryn A Beauchamp
BACKGROUND/AIMS: The management of extracerebral collections of fluid in patients with hydrocephalus can be problematic for either their simultaneous separate management or sequential management, each of which may require multiple surgeries and the management of external drains. The object of this report is to review the experience with a shunt configuration that simultaneously diverts ventricular fluid and extracerebral fluid, whether subdural or subarachnoid in location, through different outflow resistances...
September 22, 2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28931770/comparison-of-arterial-spin-labeling-perfusion-images-at-different-spatial-normalization-methods-based-on-voxel-based-statistical-analysis
#16
Kazuki Tani, Motohira Mio, Tatsuo Toyofuku, Shinichi Kato, Tomoya Masumoto, Tetsuya Ijichi, Masatoshi Matsushima, Shoichi Morimoto, Takumi Hirata
PURPOSE: Spatial normalization is a significant image pre-processing operation in statistical parametric mapping (SPM) analysis. The purpose of this study was to clarify the optimal method of spatial normalization for improving diagnostic accuracy in SPM analysis of arterial spin-labeling (ASL) perfusion images. METHODS: We evaluated the SPM results of five spatial normalization methods obtained by comparing patients with Alzheimer's disease or normal pressure hydrocephalus complicated with dementia and cognitively healthy subjects...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28931297/-intracranial-pressure-evaluation-by-ophthalmologist
#17
J Čmelo, R Illéš, J Šteňo
The value of ICT is important in diagnosis of the diseases of the eye and orbit Methods for direct measurement of intracranial pressure (ICT) are exact, but they are invasive and there is some risk of infection and damage of the tissue. Currently there are 2 valid indirect methods of mesurement of IKT. Digital Ophthalmodynamometry (D-ODM) and Transcranial Doppler ultrasonography (TDU). D-ODM is a non-invasive method for measuring of the Pulsating Venous Pressure (VPT). We can measure VPT by the pulse phenomena...
2017: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/28923529/can-mri-water-apparent-diffusion-coefficient-adc-value-discriminate-between-idiopathic-normal-pressure-hydrocephalus-alzheimer-s-disease-and-subcortical-vascular-dementia
#18
Adrien Goujon, Mehdi Mejdoubi, Yvonne Purcell, Rishika Banydeen, Sylvie Colombani, Alessandro Arrigo
Numerous similarities in MRI and clinical symptoms exist between Alzheimer's disease (AD), subcortical vascular dementia (sVD) and possible idiopathic normal pressure hydrocephalus (iHPN). The aim of this study is to explore mean apparent coefficient diffusion (ADC) difference between theses diseases in different periventricular and deep white matter areas, as compared to healthy controls. This retrospective study analyzed mean ADC values of 120 patients in normal appearing deep white matter and lenticular nuclei, frontal, caudate nuclei corpus and parietal periventricular and deep white matter areas INPH group showed significantly lower ADC than sVD group in frontal periventricular region (1567...
September 15, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28919849/interhemispheric-resting-state-functional-connectivity-predicts-severity-of-idiopathic-normal-pressure-hydrocephalus
#19
Yousuke Ogata, Akihiko Ozaki, Miho Ota, Yurie Oka, Namiko Nishida, Hayato Tabu, Noriko Sato, Takashi Hanakawa
Idiopathic normal pressure hydrocephalus (iNPH) is characterized by a clinical triad (gait disturbance, dementia, and urinary incontinence), and by radiological findings of enlarged ventricles reflecting disturbance of central spinal fluid circulation. A diagnosis of iNPH is sometimes challenging, and the pathophysiological mechanisms underlying the clinical symptoms of iNPH remain largely unknown. Here, we used an emerging MRI technique, resting-state functional connectivity MRI (rsfcMRI), to develop a subsidiary diagnostic technique and to explore the underlying pathophysiological mechanisms of iNPH...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28904452/long-term-response-of-cerebrospinal-fluid-pressure-in-patients-with-idiopathic-intracranial-hypertension-a-prospective-observational-study
#20
V Abdul Gafoor, B Smita, James Jose
BACKGROUND: Idiopathic intracranial hypertension (IIH) is increased intracranial pressure (ICP) with normal cerebrospinal fluid (CSF) contents, in the absence of an intracranial mass, hydrocephalus, or other identifiable causes. The current knowledge of the treatment outcome of IIH is limited, and the data on the natural history of this entity are scant. OBJECTIVE: The objective of the study is to study the treatment response of IIH by serially measuring the CSF opening pressure and to delineate the factors influencing the same...
July 2017: Annals of Indian Academy of Neurology
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