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JOURNAL ARTICLE
Elrika Anastasia Wijaya, Purboyo Solek, Dedi Rachmadi, Sri Endah Rahayuningsih, Rodman Tarigan, Dany Hilmanto
INTRODUCTION: As the highest function in the brain that regulates our daily activity, executive dysfunction might affect someone's health-related quality of life (HRQoL), especially in those with chronic diseases, including chronic kidney disease (CKD). Neurocognitive functions, including intelligence quotient (IQ) and executive function can be affected through various mechanisms in CKD. However, there was still no specific study regarding how IQ and executive function might affect HRQoL in children with CKD...
2024: International Journal of Nephrology and Renovascular Disease
#22
JOURNAL ARTICLE
Catherine Morin, Maude Pichette, Naoual Elftouh, Benoit Imbeault, Louis-Philippe Laurin, Jean-Philippe Lafrance, Rémi Goupil, Annie-Claire Nadeau-Fredette
BACKGROUND: Patients with advanced chronic kidney disease have lower health-related quality of life (HRQOL) than the general population. There is uncertainty regarding patterns of HRQOL changes before dialysis initiation. This study aimed to characterise HRQOL trajectory and assess its potential association with intended dialysis modality. METHODS: This prospective single-centre cohort study followed adults with an estimated glomerular filtration rate ≤15 mL/min/1...
January 7, 2024: Peritoneal Dialysis International
#23
REVIEW
Sara N Davison, Wolfgang Pommer, Mark A Brown, Claire A Douglas, Samantha L Gelfand, Irmingarda P Gueco, Barnaby D Hole, Sumiko Homma, Rümeyza T Kazancıoğlu, Harumi Kitamura, Sahar H Koubar, Rene Krause, Kelly C Li, Aoife C Lowney, Shankar P Nagaraju, Abdou Niang, Gregorio T Obrador, Yoichi Ohtake, Jane O Schell, Jennifer S Scherer, Brendan Smyth, Kaichiro Tamba, Nandini Vallath, Nicola Wearne, Elena Zakharova, Carlos Zúñiga, Frank P Brennan
Integrated kidney care requires synergistic linkage between preventative care for people at risk for chronic kidney disease and health services providing care for people with kidney disease, ensuring holistic and coordinated care as people transition between acute and chronic kidney disease and the 3 modalities of kidney failure management: conservative kidney management, transplantation, and dialysis. People with kidney failure have many supportive care needs throughout their illness, regardless of treatment modality...
January 2024: Kidney International
#24
REVIEW
Ethan Slouha, Hanin Al-Geizi, Brandon R Albalat, Venkata Sathya Burle, Lucy A Clunes, Theofanis F Kollias
Despite the advancement in medicine, there is still a lack of understanding of the sex disparities in disease onset, progression, treatment, and outcome. In some life-threatening acute conditions, despite most patients with these illnesses being males, females have a significantly higher chance of mortality. This can be due to the differences in disease progression or healthcare disparities in managing the illness between the sexes. Treatment of illnesses tends to be more conservative for women without an explanation, but this disparity is due to the healthcare provider...
December 2023: Curēus
#25
JOURNAL ARTICLE
Matt Haley, Nasim Khosravi Foroutan, Juliann M Gronquist, Raju Reddy, Raghav Wusirika, Akram Khan
Managing sepsis and fluid resuscitation in patients with chronic kidney disease or end-stage renal disease is challenging for health care providers. Nurses are essential for early identification and treatment of these patients. Nurse education on assessing perfusion and implementing 3-hour bundled care can improve mortality rates in patients with sepsis. In this scoping review, initial screening identified 1176 articles published from 2015 through 2023 in the National Library of Medicine database; 29 articles were included in the literature summary and evidence synthesis...
January 1, 2024: American Journal of Critical Care
#26
REVIEW
Lan Wei, Jingjing Gao, Liangzhi Wang, Qianru Tao, Chao Tu
Diabetic angiopathy, which includes diabetic kidney disease (DKD), cardio-cerebrovascular disease, and diabetic retinopathy (DR) among other diseases, is one of the most common complications affecting diabetic patients. Among these, DKD, which is a major cause of morbidity and mortality, affects about 40% of diabetic patients. Similarly, DR involves retinal neovascularization and neurodegeneration as a result of chronic hyperglycemia and is the main cause of visual impairment and blindness. In addition, inflammation also promotes atherosclerosis and diabetes, with atherosclerosis-related cardiovascular diseases being often a main cause of disability or death in diabetic patients...
2023: Therapeutic Advances in Endocrinology and Metabolism
#27
JOURNAL ARTICLE
Xenofon M Sakellariou, Christos S Katsouras, Michail I Papafaklis, Christos Floros, Lampros K Michalis, Dimitri Karmpaliotis
PURPOSE: Contrast media (CM)-associated adverse effects including mainly acute kidney injury and hypersensitivity reactions still remain a significant treatment burden to vulnerable patients requiring percutaneous coronary intervention (PCI). The complete omission of CM administration accompanied by intravascular ultrasound (IVUS) guidance may offer an appropriate revascularization treatment. METHODS: We hereby present a case series of four patients with challenging coronary lesions and relative/absolute contraindications to CM use [(hypersensitivity reaction owning to CM, history of contrast-induced acute kidney injury, solitary kidney, or advanced chronic kidney disease (CKD)] who underwent absolute zero-contrast IVUS-guided PCI following a predetermined protocol...
December 17, 2023: Cardiovascular Revascularization Medicine: Including Molecular Interventions
#28
JOURNAL ARTICLE
Maria R Dahm, Suzanne Eggins Raine, Diana Slade, Laura J Chien, Alice Kennard, Giles Walters, Tony Spinks, Girish Talaulikar
BACKGROUND: Effective interpersonal communication is critical for shared decision-making (SDM). Previous SDM communication training in nephrology has lacked context-specific evidence from ethnographic analysis of SDM interactions with older patients considering treatment options of end stage kidney disease (ESKD). This study explores communication strategies in SDM discussions in nephrology, specifically focusing on older patients considering dialysis as kidney replacement therapy (KRT)...
December 21, 2023: BMC Nephrology
#29
JOURNAL ARTICLE
Maho Terashita, Umut Selamet, Shonali Midha, Omar Nadeem, Jacob Laubach, Helmut G Rennke, Naoka Murakami
INTRODUCTION: Monoclonal gammopathy of renal significance (MGRS) is characterized by monoclonal immunoglobulin deposition in kidneys. However, monoclonal immunoglobulin and responsible clone(s) are not always detectable. Treatment response and kidney outcome of MGRS without detectable clones remain unclear. METHODS: In this single-center, retrospective cohort study, we identified MGRS without detectable clones from our biopsy repository between 2010 and 2022. We investigated the correlations between treatment regimens and kidney outcomes defined by proteinuria and estimated glomerular filtration rate (eGFR), and the impact of repeat kidney biopsy...
December 2023: KI Reports
#30
REVIEW
Matthew B Lanktree, Timothy Kline, York Pei
While autosomal dominant polycystic kidney disease (ADPKD) is a dichotomous diagnosis, substantial variability in disease severity exists. Identification of inherited risk through family history, genetic testing, and environmental risk factors through clinical assessment are important components of risk assessment for optimal management of patients with ADPKD. Genetic testing is especially helpful in cases with diagnostic uncertainty, particularly in cases with no apparent family history, in young cases (age less than 25 years) where a definitive diagnosis is sought, or in atypical presentations with early, severe, or discordant findings...
September 2023: Adv Kidney Dis Health
#31
JOURNAL ARTICLE
Manoharan Renugasundari, Subramaniyam Velkumary, Sreejith Parameswaran, Nivedita Nanda, Jean Fredrick
Patients with chronic kidney disease (CKD) are at a higher risk of cognitive impairment. Poor quality of life and decreased compliance are frequently observed with cognitive decline among CKD patients. Cognitive impairment among Stage 5 CKD patients varies with different modalities of treatment, and contradicting results have been reported. Fifty-four medically stable Stage 5 CKD patients undergoing different modalities of treatment were recruited: Patients with Stage 5 CKD on maintenance hemodialysis (HD) (n = 18), continuous ambulatory peritoneal dialysis (CAPD) (n = 18), and conservative management (CM) (n = 18)...
January 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
#32
JOURNAL ARTICLE
Hiroyuki Inoshita, Daisuke Asaoka, Kei Matsuno, Naotake Yanagisawa, Yusuke Suzuki, Katsumi Miyauchi
Sarcopenia is a poor prognostic factor in patients with chronic kidney disease (CKD). Adequate dietary patterns are important for preventing sarcopenia; however, evidence regarding the underlying association between sarcopenia and diet is insufficient. Therefore, in this study, we aimed to investigate the association between sarcopenia and dietary patterns in CKD patients receiving conservative treatment. In this cross-sectional study, 441 patients with conservative CKD were examined using the Asian Working Group for Sarcopenia diagnostic criteria...
December 1, 2023: Nutrients
#33
JOURNAL ARTICLE
Onislene Alves Evangelista de Almeida, Maria Eduarda Freitas de Lima, Walterlânia Silva Santos, Bárbara Louise Moreira Silva
OBJECTIVE: to evaluate the evidence about telehealth strategies in caring for people with chronic kidney disease. METHOD: integrative literature review. The search for primary studies was carried out in six databases: PubMed/MEDLINE, Web of Science, EMBASE, CINAHL, LILACS, and Scopus. The sample consisted of 48 articles published between 2000 and 2021. The telehealth strategy was applied by a multidisciplinary team of doctors, nurses, pharmacists, nutritionis, and social workers...
2023: Revista Latino-americana de Enfermagem
#34
JOURNAL ARTICLE
Çağla Serpil Doğan, Sevgin Taner, Betül Durucu Tiryaki, Demet Alaygut, Neşe Özkayın, Aslıhan Kara, Aylin Gençler, Ayşe Seda Pınarbaşı, Hülya Nalçacıoğlu, Selçuk Yüksel, Okan Akacı, Esra Karabağ Yılmaz, Sevgi Yavuz, Kenan Doğan, Rumeysa Yasemin Çiçek Gülşan, Gülşah Kaya Aksoy, Neslihan Çiçek, Bağdagül Aksu, Nuran Küçük, Fatma Şemsa Altugan, Şenay Zırhlı Selçuk, Funda Baştuğ, Gökçen Erfidan, Bahriye Atmış, Arife Uslu Gökçeoğlu, Esra Nagehan Akyol Önder, Ahmet Mithat Elmacı, Nurcan Cengiz, Kaan Gülleroğlu, Ebru Bekiroğlu Yılmaz, Aslı Çelebi Tayfur, Gülsün Gülay Yılmaz, Sİbel Yel, Cemile Pehlivanoğlu, Cihangir Akgün, Mehtap Akbalık Kara, Beltinge Demircioğlu Kılıç, Özgür Özdemir Şimşek, Melike Yucal, Buket Esen Ağar, Metin Kaya Gürgöze, İsmail Yağmur, Ömer Madsar, Demet Tekcan Karalı, İlknur Girişgen, Ece Demirci Bodur, Elif Çomak, İbrahim Gökçe, Mehtap Kaya, Yılmaz Tabel, Neslihan Günay, Rüveyda Gülmez, Salim Çalışkan
BACKGROUND: Myelomeningocele (MMC) is highly prevalent in developing countries, and MMC-related neurogenic bladder is an important cause of childhood chronic kidney disease (CKD). This nationwide study aimed to evaluate demographic and clinical features of pediatric patients with MMC in Turkey and risk factors associated with CKD stage 5. METHODS: Data from children aged 0-19 years old, living with MMC in 2022, were retrospectively collected from 27 pediatric nephrology centers...
December 2, 2023: Pediatric Nephrology
#35
REVIEW
Sheng-Fu Chen, Hann-Chorng Kuo
The main problems of neurogenic lower urinary tract dysfunction (NLUTD) in patients with spinal cord injury (SCI) consist of impaired urine storage, impaired bladder emptying, or both. The priorities in the management of SCI-NLUTD should be preservation of renal function, followed by freedom from urinary tract infections and improvement of quality of life. Management of NLUTD in patients with SCI must be based on urodynamic findings rather than clinical evaluations. In the hospital without urodynamic equipment, careful measurement of intravesical pressure and safety functional bladder capacity in conjunction with clinical assessment are also feasible...
November 30, 2023: International Urology and Nephrology
#36
William Harrison, Patrick Gough, Sheliyan Raveenthiran, David Sillar
Xanthogranulomatous pyelonephritis (XGP) is a rare form of chronic pyelonephritis characterized by granulomatous tissue replacing renal parenchyma, primarily in adults. It's often linked to chronic obstruction, urolithiasis, and pyelonephritis, with rare associations with psoas abscess or fistula. A 15-year-old girl, initially treated conservatively for suspected pyelonephritis, underwent CT imaging due to non-response. This revealed XGP with a sizable psoas abscess caused by a kidney-psoas muscle fistula and renal calculus migration...
November 2023: Urology Case Reports
#37
Roberta Passaro, Pierluigi D'Angiò, Simona Laurino, Giuseppe Gigliotti, Antonio Massa, Antonio Mancini, Annalisa Gonnella, Anna Giammarino, Gianmarco Borriello
The abuse of anabolic androgenic steroids (AAS) for competitive (and non-competitive) purposes for bodybuilding practice is increasingly common. The consequences of these substances on the various organs are only partially known. Cases of FSGS following the use of AAS have been reported in the literature, even with evolution to ESKD. We describe three cases of bodybuilding athletes who presented alterations in renal function indices after taking AAS for a long time. Three renal biopsies were performed with histological diagnosis of FSGS collapsing variant...
October 26, 2023: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
#38
JOURNAL ARTICLE
Jeffrey A Beamish, Asha C Telang, Madison C McElliott, Anas Al-Suraimi, Mahboob Chowdhury, Jenna T Ference-Salo, Edgar A Otto, Rajasree Menon, Abdul Soofi, Joel M Weinberg, Sanjeevkumar R Patel, Gregory R Dressler
Acute kidney injury (AKI) is a common condition that lacks effective treatments. In part, this shortcoming is due to an incomplete understanding of the genetic mechanisms that control pathogenesis and recovery. Identifying the molecular and genetic regulators unique to nephron segments that dictate vulnerability to injury and regenerative potential could lead to new therapeutic targets to treat ischemic kidney injury. Pax2 and Pax8 are homologous transcription factors with overlapping functions that are critical for kidney development and are re-activated in AKI...
November 17, 2023: Kidney International
#39
Valentina Bruno, David Barth, Arenn Jauhal
RATIONALE: Thrombotic microangiopathy (TMA) is a spectrum of rare diseases characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ damage. Differentiating pre-eclampsia, HELLP (Hemolysis, Elevated Liver enzymes, Low Platelets) syndrome and atypical hemolytic uremic syndrome (aHUS) during pregnancy may be diagnostically challenging yet important as the treatment pathways differ. Most cases of aHUS are associated with dysregulation of the complement alternative pathway, for which current guidelines recommend prompt treatment with complement C5 inhibitor to prevent chronic sequelae...
2023: Canadian Journal of Kidney Health and Disease
#40
REVIEW
Haiying Shu, Zhen Zhang, Jieting Liu, Peijian Chen, Can Yang, Yan Wu, Dan Wu, Yanan Cao, Yanhui Chu, Luxin Li
Diabetic nephropathy (DN) is a prevalent chronic microvascular complication associated with diabetes mellitus and represents a major cause of chronic kidney disease and renal failure. Current treatment strategies for DN primarily focus on symptom alleviation, lacking effective approaches to halt or reverse DN progression. Circular RNA (circRNA), characterized by a closed-loop structure, has emerged as a novel non-coding RNA regulator of gene expression, attributed to its conservation, stability, specificity, and multifunctionality...
December 2023: Biomedicine & Pharmacotherapy
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