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https://www.readbyqxmd.com/read/28812445/-half-a-woman-half-a-man-that-is-how-they-make-me-feel-a-qualitative-study-of-rural-jordanian-women-s-experience-of-infertility
#1
Mayada A Daibes, Reema R Safadi, Tarek Athamneh, Iman F Anees, Rose E Constantino
Infertility is a health problem encompassing physical, psychological and social consequences that may threaten women's quality of life. Few studies have been conducted in Jordan examining rural women's experiences of infertility. This study aimed to explore responses to infertility and its consequences in the Jordanian rural sociocultural context. Using a descriptive qualitative design, data were collected between April and September 2016 from a fertility clinic in a military hospital in Northern Jordan. Semi-structured interviews were conducted with 14 purposively selected Jordanian women...
August 16, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28810949/analysis-of-non-pivotal-bioequivalence-studies-submitted-in-abbreviated-new-drug-submissions-for-delayed-release-drug-products
#2
Paramjeet Kaur, Xiaojian Jiang, Ethan Stier
The US FDA's rule on "Requirements for Submission of Bioequivalence Data" requiring submission of all bioequivalence (BE) studies conducted on the same formulation of the drug product submitted for approval was published in Federal Register in January 2009. With the publication of this rule, we evaluated the impact of data from non-pivotal BE studies in assessing BE and identified the reasons for failed in vivo BE studies for generic oral delayed-release (DR) drug products only. We searched the Agency databases from January 2009 toDecember 2016 to identify Abbreviated New Drug Applications (ANDAs) submitted for DR drug products containing non-pivotal BE studies...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28808998/microfluidics-mass-spectrometry-of-protein-carbohydrate-interactions-applications-to-the-development-of-therapeutics-and-biomarker-discovery
#3
Alina D Zamfir
The functional interactions of carbohydrates and their protein receptors are the basis of biological events critical to the evolution of pathological states. Hence, for the past years, such interactions have become the focus of research for the development of therapeutics and discovery of novel glycan biomarkers based on their binding affinity. Due to the high sensitivity, throughput, reproducibility, and capability to ionize minor species in heterogeneous mixtures, microfluidics-mass spectrometry (MS) has recently emerged as a method of choice in protein-glycan interactomics...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28808881/a-proposal-to-detect-the-double-submission-of-a-manuscript-sent-for-review
#4
Manjur Kolhar, Abdalla Alameen, Safar Bin Bkhit AlMudara
Along with the rapid growth of editorial systems and publishers, the number of research articles is increasing, which creates a need for an effective dissemination strategy. Researchers commonly use editorial systems in a candid manner. However, when researchers concurrently submit the same contribution in more than one editorial system, it is considered unethical. In this paper, we propose a novel approach called DeMSum for detecting such duplicate submissions. DeMSum verifies a manuscript (MS) by processing the MS attributes that are accessed through the editorial system...
August 14, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28807308/presence-and-species-identity-of-rumen-flukes-in-cattle-and-sheep-in-the-netherlands
#5
H W Ploeger, L Ankum, L Moll, D C K van Doorn, G Mitchell, P J Skuce, R N Zadoks, M Holzhauer
The purpose of the study was to gain knowledge about the prevalence and identity of rumen flukes (RF) in cattle and sheep in the Netherlands. Routine faecal examinations of diagnostic submissions between May 2009 and September 2014 showed a mean annual herd or flock RF prevalence of 15.8% for cattle and 8.0% for sheep. Prevalence in cattle was higher after 2012 than before, which may reflect a change in detection method as well as an increase in true prevalence. During November and December 2014, an abattoir survey was conducted to allow for scoring of rumen fluke burden and to obtain specimens for molecular species characterization...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28805361/medicare-program-hospital-inpatient-prospective-payment-systems-for-acute-care-hospitals-and-the-long-term-care-hospital-prospective-payment-system-and-policy-changes-and-fiscal-year-2018-rates-quality-reporting-requirements-for-specific-providers-medicare
#6
(no author information available yet)
We are revising the Medicare hospital inpatient prospective payment systems (IPPS) for operating and capital-related costs of acute care hospitals to implement changes arising from our continuing experience with these systems for FY 2018. Some of these changes implement certain statutory provisions contained in the Pathway for Sustainable Growth Rate (SGR) Reform Act of 2013, the Improving Medicare Post-Acute Care Transformation Act of 2014, the Medicare Access and CHIP Reauthorization Act of 2015, the 21st Century Cures Act, and other legislation...
August 14, 2017: Federal Register
https://www.readbyqxmd.com/read/28804603/towards-a-more-transparent-hta-process-in-poland-new-polish-hta-methodological-guidelines
#7
Krzysztof Lach, Michal Dziwisz, Cécile Rémuzat, Mondher Toumi
Introduction: Health technology assessment (HTA) in Poland supports reimbursement decisions via the Polish HTA Agency (AOTMiT), whose guidelines were updated in 2016. Methods: We identified key changes introduced by the update and, before guideline publication, analysed discrepancies between AOTMiT assessments and the submitting marketing authorisation holders (MAHs) to elucidate the context of the update. We compared the clarity and detail of the new guidelines versus those of the UK's National Institute for Health and Care Excellence (NICE)...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28804600/analysis-of-health-economics-assessment-reports-for-pharmaceuticals-in-france-understanding-the-underlying-philosophy-of-ceesp-assessment
#8
Mondher Toumi, Anastasiia Motrunich, Aurélie Millier, Cécile Rémuzat, Christos Chouaid, Bruno Falissard, Samuel Aballéa
Background: Despite the guidelines for Economic and Public Health Assessment Committee (CEESP) submission having been available for nearly six years, the dossiers submitted continue to deviate from them, potentially impacting product prices. Objective: to review the reports published by CEESP, analyse deviations from the guidelines, and discuss their implications for the pricing and reimbursement process. Study design: CEESP reports published until January 2017 were reviewed, and deviations from the guidelines were extracted...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28803221/reflective-student-narratives-honing-professionalism-and-empathy
#9
Upreet Dhaliwal, Satendra Singh, Navjeevan Singh
The affective domain is not explicitly targeted during medical studies and poor skills in this domain may lead to conflict when dealing with patients. Reflective narratives are said to promote humanitarianism and professional development. We aimed to examine reflective narratives written by medical students in our institution for content relating to ethical and professional Attitude and Behaviour, Communication, respect for Diversity and Disability, and Empathy (the ABCDE paradigm). We were also interested in understanding how far the students enjoyed learning through the writing of narratives and in determining their perceived learning from the exercise...
July 18, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28803014/fertility-of-lactating-holstein-cows-submitted-to-a-double-ovsynch-protocol-and-timed-artificial-insemination-versus-artificial-insemination-after-synchronization-of-estrus-at-a-similar-day-in-milk-range
#10
V G Santos, P D Carvalho, C Maia, B Carneiro, A Valenza, P M Fricke
Our objective was to compare the AI submission rate and pregnancies per artificial insemination (P/AI) at first service of lactating Holstein cows submitted to a Double-Ovsynch protocol and timed artificial insemination (TAI) versus artificial insemination (AI) to a detected estrus after synchronization of estrus at a similar day in milk range. Lactating Holstein cows were randomly assigned to receive their first TAI after a Double-Ovsynch protocol (DO; n = 294) or to receive their first AI after a synchronized estrus (EST; n = 284)...
August 9, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28802519/espen-guidelines-on-nutritional-support-for-polymorbid-internal-medicine-patients
#11
Filomena Gomes, Philipp Schuetz, Lisa Bounoure, Peter Austin, María Ballesteros-Pomar, Tommy Cederholm, Jane Fletcher, Alessandro Laviano, Kristina Norman, Kalliopi-Anna Poulia, Paula Ravasco, Stephane M Schneider, Zeno Stanga, C Elizabeth Weekes, Stephan C Bischoff
BACKGROUND & AIMS: Polymorbidity (also known as multimorbidity) - defined as the co-occurrence of at least two chronic health conditions - is highly prevalent, particularly in the hospitalized population. Nonetheless, clinical guidelines largely address individual diseases and rarely account for polymorbidity. The aim of this project was to develop guidelines on nutritional support for polymorbid patients hospitalized in medical wards. METHODS: The methodology used for the development of the current project follows the standard operating procedures for ESPEN guidelines...
July 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28799798/abstracts-from-dietetic-research-event-june-8-and-9-2017
#12
(no author information available yet)
St John's, Newfoundland was the host city of the 2017 Dietitians of Canada Annual Conference. Through the support of Dietitians of Canada and CFDR, the 2017 event was both an exciting and informative exchange of research and experience-sharing efforts that inspired attendees. The submissions for this year's Canadian Foundation for Dietetic Research (CFDR) event represented the diversity of dietetic research conducted within Canada. The topics highlighted from this year's abstracts included: Clinical Research; Community-based Nutritional Care; Determinants of Food Choice; Dietary Intake; Dietetic Practice and Education; Food Security; Nutrition and Health Education; Nutritional Assessment and Therapy; Nutrition Attitudes; Nutrition Strategy Development Patient Services; Professional Development; Vulnerable Groups and their Nutritional Needs; and, Wellness and Public Health...
September 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28799703/the-pico-game-an-innovative-strategy-for-teaching-step-1-in-evidence-based-practice
#13
Kerry A Milner, Sheryl Cosme
This column shares the best evidence-based strategies and innovative ideas on how to facilitate the learning and implementation of EBP principles and processes by clinicians as well as nursing and interprofessional students. Guidelines for submission are available at https://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1741-6787.
August 11, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28798527/specific-pathologist-responses-for-standard-for-exchange-of-nonclinical-data-send
#14
REVIEW
Atsushi Watanabe, Osamu Kusuoka, Norihiro Sato, Osamu Nakazono, Michael Wasko, Daniel Potenta, Dai Nakae, Hirofumi Hatakeyama, Hijiri Iwata, Misaki Naota, Takayuki Anzai
The Standard for Exchange of Nonclinical Data (SEND), introduced by the US Food and Drug Administration (FDA), is a scheme for the computerization, electronic application, and screening of preclinical data. Since its establishment, related organizations have been working together to implement SEND. However, it is difficult for individual pharmaceutical companies that often outsource to achieve complete compliance with SEND; hence, the cooperation of contract research organizations (CROs) and SEND Registered Solution Providers (RSPs) is indispensable...
July 2017: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/28798432/bdj-team-now-accepts-manuscript-submissions
#15
(no author information available yet)
No abstract text is available yet for this article.
August 11, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28795393/investigation-of-cross-contamination-among-human-cell-lines-used-in-china
#16
Mingzhen Wang, Meimei Yang, Yuehong Liu, Yaqing Huang, Fang Ye, Congyi Zheng, Chao Shen
Increasing attention has been paid to the hazard of cell line cross-contamination. More journals are requiring that cell lines be authenticated prior to manuscript submission. China Center for Type Culture Collection (CCTCC) has authenticated cell lines for publications in the International Journal of Cancer since 2009. Between 2010 and 2016, we authenticated 485 cell lines from 66 Chinese universities and research institutes. Almost 50% of cell lines were misidentified, most were completely replaced by other cell lines (mainly HeLa and its sublines)...
August 10, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28795135/male-and-female-mice-lacking-neuroligin-3-modify-the-behavior-of-their-wild-type-littermates
#17
Shireene Kalbassi, Sven O Bachmann, Ellen Cross, Victoria H Roberton, Stéphane J Baudouin
In most mammals, including humans, the postnatal acquisition of normal social and nonsocial behavior critically depends on interactions with peers. Here we explore the possibility that mixed-group housing of mice carrying a deletion of Nlgn3, a gene associated with autism spectrum disorders, and their wild-type littermates induces changes in each other's behavior. We have found that, when raised together, male Nlgn3 knockout mice and their wild-type littermates displayed deficits in sociability. Moreover, social submission in adult male Nlgn3 knockout mice correlated with an increase in their anxiety...
July 2017: ENeuro
https://www.readbyqxmd.com/read/28793068/incorporation-of-new-medicines-by-the-national-commission-for-incorporation-of-technologies-2012-to-june-2016
#18
Rosângela Caetano, Rondineli Mendes da Silva, Érica Militão Pedro, Ione Ayala Gualandi de Oliveira, Aline Navega Biz, Pamela Santana
The National Commission for incorporation of Health Technologies (CONITEC), established in 2011, advises the Ministry of Health in decisions related to the incorporation, exclusion or change of medicines, products and procedures in the Unified Health System (SUS).The study investigated the decision-making process, profile of demands and incorporation of new medicines in the SUS from January/2012 to June/2016, based on data available on the CONITEC website. All submissions were evaluated and characterized by technology and applicant type...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28792996/-the-legacy-of-cabanis-a-hypothesis-on-the-roots-of-medical-education-in-brazil
#19
Naomar Almeida-Filho
Georges Cabanis was a reformer of clinical practice and medical education who laid the conceptual foundations during the French Revolution for the development of education in France over the course of the 19th century. The model, in turn, marked the organization of educational systems in many Latin American countries. The objective of this article is to present and justify a hypothesis: the model of medical education still hegemonic in Brazil is still based upon the Cabanisian reform, holding a linear and Cartesian conceptual perspective, with a discipline-based curriculum, traditional teaching formats, and submission to corporate professional logic...
August 7, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28792801/timeliness-from-submission-to-publication-working-together-on-key-steps-in-the-process
#20
Thomas H Berquist
No abstract text is available yet for this article.
June 2017: AJR. American Journal of Roentgenology
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