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Rosalía Cascón-Pereira, Shiona Chillas, Jerry Hallier
This study examines "identity work" among hybrid doctor-managers (DMs) in the Spanish National Health System to make sense of their managerial roles. In particular, the meanings underlying DMs experience of their hybrid role are investigated using a Grounded Theory methodology, exposing distinctions in role-meanings. Our findings provide evidence that using different social sources of comparison (senior managers or clinicians) to construct the meaning of managerial roles leads to different role-meanings and role identities, which are the source of the two established types of DM in the literature, the reluctant and the enthusiast...
October 3, 2016: Social Science & Medicine
Dimuthu C Senevirathna, Victoria L Blair, Melissa V Werrett, Philip C Andrews
Eight novel bismuth(III) sulfonato compounds have been synthesized and characterized using the sonochemical reaction of Bi2O3 with a range of sulfonic acids, including 2,5-dimethylbenzenesulfonic acid (2,5-DMSH), 2,4-dinitrobenzenesulfonic acid (2,4-DNSH), 2,5-dichlorobenzenesulfonic acid (2,5-DCSH), 1,2-benzenedisulfonic acid (1,2-BDSH2), 1,3-benzenedisulfonic acid (1,3-BDSH2), 2-sulfobenzoic acid (2-SBH2), 3-sulfobenzoic acid (3-SBH2), and 2-naphthalenesulfonic acid (NPSH). Six of the complexes (1, 2, 4, and 6-8) were structurally characterized through single-crystal X-ray crystallography...
October 14, 2016: Inorganic Chemistry
K G Sorwell, L Renner, A R Weiss, M Neuringer, S G Kohama, H F Urbanski
Estradiol supplementation has been shown to enhance cognitive performance in old ovariectomized rhesus macaques (Macaca mulatta). To determine if similar benefits could be achieved in perimenopausal animals using alternative hormonal supplements we administered dehydroepiandrosterone (DHEA) to old ovary-intact female rhesus macaques for ~2.5 months. Using computerized touchscreen memory tasks, including delayed response (DR) and delayed matching-to-sample (DMS), we observed improved performance with time in all of the animals but failed to detect a significant effect of DHEA...
October 13, 2016: Genes, Brain, and Behavior
Marco Manfredini, Giovanni Pellacani, Lorena Losi, Monia Maccaferri, Aldo Tomasi, Giovanni Ponti
AIM: To evaluate clinical, pathologic and genetic features of desmoplastic melanoma (DM). MATERIALS & METHODS: Analysis of all DM records from 1991 to 2015. RESULTS: The most common location of DMs was the head and neck (69%); median age and follow-up were 60.5 and 7.3 years, respectively. A familial predisposition for DMs and others malignancies was analyzed. Thin Breslow thickness (<4.5 mm) was associated with an intraepidermal component or a previous lentigo maligna, whereas high Breslow thickness (>4...
October 12, 2016: Future Oncology
Lysann Wagener, Andreas Nieder
Songbirds possess acute vision. How higher brain centers represent basic and parameterized visual stimuli to process sensory signals according to their behavioral importance has not been studied in a systematic way. We therefore examined how carrion crows (Corvus corone) and their nidopallial visual neurons process global visual motion information in dynamic random-dot displays during a delayed match-to-sample (DMS) task. The behavioral data show that moderately fast motion speeds (16 degrees of visual angle/second) result in superior direction discrimination performance...
October 8, 2016: European Journal of Neuroscience
Spiros Manolakos, Francy Sinatra, Leila Nikkhouy Albers, Kevin Hufford, James Alberti, Erkinjon G Nazarov, Theresa Evans-Nguyen
Differential mobility spectrometry (DMS) is applied to the analysis of inorganic mixtures relevant to nuclear forensics. Three primary components of potential radiological dispersal devices (RDDs): cobalt, cesium, and strontium, were studied by DMS to demonstrate rapid sample clean-up when coupled to mass spectrometry. Nanosprayed salt solutions comprised of stable analogs, as proxies to these radioisotopes, and isobaric interferents were introduced to DMS. The DMS effluent was directly coupled to a mass spectrometer to confirm the elemental identity of the separated clusters...
October 7, 2016: Analytical Chemistry
Erik Hans Hoffmann, Andreas Tilgner, Roland Schrödner, Peter Bräuer, Ralf Wolke, Hartmut Herrmann
Oceans dominate emissions of dimethyl sulfide (DMS), the major natural sulfur source. DMS is important for the formation of non-sea salt sulfate (nss-SO4 (2-)) aerosols and secondary particulate matter over oceans and thus, significantly influence global climate. The mechanism of DMS oxidation has accordingly been investigated in several different model studies in the past. However, these studies had restricted oxidation mechanisms that mostly underrepresented important aqueous-phase chemical processes. These neglected but highly effective processes strongly impact direct product yields of DMS oxidation, thereby affecting the climatic influence of aerosols...
September 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
Alberta Palazzo, Olivier Bluteau, Kahia Messaoudi, Francesco Marangoni, Yunhua Chang, Sylvie Souquere, Gérard Pierron, Valérie Lapierre, Yi Zheng, William Vainchenker, Hana Raslova, Najet Debili
BACKGROUND: Cytoskeleton rearrangements are essential in platelet release. The RHO small GTPase family, as regulators of the actin cytoskeleton, plays an important function in proplatelet formation. In the neuronal system, CDC42 is involved in the axone formation, a process that combined elongation and branching as proplatelet formation. OBJECTIVE: To analyze the role of CDC42 and its effectors of the WASP family on proplatelet formation METHODS: Human MKs were obtained from CD34(+) cells...
September 29, 2016: Journal of Thrombosis and Haemostasis: JTH
Zlatko Zimet, Marjan Bilban, Mateja Marc Malovrh, Peter Korošec, Borut Poljšak, Joško Osredkar, Mira Šilar
This study was to investigate whether working in conditions of elevated concentrations of mine gases (CO2, CO, CH4, DMS) and dust may result in oxidative stress. Coal miners (n=94) from the Velenje Coal mine who were arranged into control group and three groups according to a number of consecutive working days. 8-isoprostane as a biological marker of oxidative stress was measured in exhaled breath condensate (EBC). Miners who worked for three consecutive days had higher 8-isoprostane values in EBC compared to the control group...
August 2016: Biomedical and Environmental Sciences: BES
S Murakami, M Otaki, Y Hayashi, K Higuchi, T Kobayashi, Y Torii, E Yokoyama, R Azuma
Recently, submandibular abscesses associated with Actinomyces denticolens have been reported in horses. The actinomycotic clumps have been observed in the tonsillar crypts. The aim of this study was to demonstrate colonisation of A denticolens in equine tonsils. Twelve equine tonsils obtained from a slaughterhouse were divided into two parts for histopathological examination and for isolation of A denticolens. When actinomycotic clumps were found in these tonsillar crypts, immunohistochemistry using hyperimmune serum against A denticolens (DMS 20671) was performed on the serial sections...
2016: Veterinary Record Open
Ida Apostolico, Luigi Aliberti, Lucia Caputo, Vincenzo De Feo, Florinda Fratianni, Filomena Nazzaro, Lucèia Fàtima Souza, Maroua Khadhr
Peganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P. harmala seeds from five different regions of Northern Africa (Algeria, Egypt, Libya, Morocco and Tunisia) was studied by GC and GC-MS analyses. A total of 105 compounds were identified, the main components being oxygenated monoterpenes and oxygenated sesquiterpenes. Eugenol is the main component in all oils...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ravi K Samala, Heang-Ping Chan, Lubomir M Hadjiiski, Mark A Helvie
With IRB approval, digital breast tomosynthesis (DBT) images of human subjects were collected using a GE GEN2 DBT prototype system. Corresponding digital mammograms (DMs) of the same subjects were collected retrospectively from patient files. The data set contained a total of 237 views of DBT and equal number of DM views from 120 human subjects, each included 163 views with microcalcification clusters (MCs) and 74 views without MCs. The data set was separated into training and independent test sets. The pre-processing, object prescreening and segmentation, false positive reduction and clustering strategies for MC detection by three computer-aided detection (CADe) systems designed for DM, DBT, and a planar projection image generated from DBT were analyzed...
October 7, 2016: Physics in Medicine and Biology
A D Bouravleuv, L L Lev, C Piamonteze, X Wang, T Schmitt, A I Khrebtov, Yu B Samsonenko, J Kanski, G E Cirlin, V N Strocov
Electronic structure of a molecular beam epitaxy-grown system of (In,Mn)As quantum dots (QDs) buried in GaAs is explored with soft-x-ray angle-resolved photoelectron spectroscopy (ARPES) using photon energies around 1 keV. This technique, ideally suited for buried systems, extends the momentum-resolving capabilities of conventional ARPES with enhanced probing depth as well as elemental and chemical state specificity achieved with resonant photoexcitation. The experimental results resolve the dispersive energy bands of the GaAs substrate buried in ∼2 nm below the surface, and the impurity states (ISs) derived from the substitutional Mn atoms in the (In,Mn)As QDs and oxidized Mn atoms distributed near the surface...
October 21, 2016: Nanotechnology
C Manterola, P Flores, T Otzen
INTRODUCTION: Floating stoma (FS) is a strategy to be considered in the context of damage control surgery (DCS). The purpose of this study is to describe the technique used and the results of a series of patients where FS was used. METHODS: Case series of relaparotomized patients at two emergency services in Temuco, Chile (2005-2014). In all of them, once drainage of septic focus or damage was controlled, the abdomen was left open with a Bogota bag (BB) and FS. Outcome variables were FS indications, morbidity, time to first replacement of BB, definitive maturation of the stoma (DMS), time to withdraw the BB and mortality...
September 8, 2016: Journal of Visceral Surgery
Yin-Xin Zeng, Zong-Yun Qiao, Yong Yu, Hui-Rong Li, Wei Luo
Dimethylsulfoniopropionate (DMSP), which is the major source of organic sulfur in the world's oceans, plays a significant role in the global sulfur cycle. This compound is rapidly degraded by marine bacteria either by cleavage to dimethylsulfide (DMS) or demethylation to 3-methylmercaptopropionate (MMPA). The diversity of genes encoding bacterial demethylation (dmdA) and DMS production (dddL and dddP) were measured in Arctic Kongsfjorden. Both dmdA and dddL genes were detected in all stations along a transect from the outer to the inner fjord, while dddP gene was only found in the outer and middle parts of the fjord...
2016: Scientific Reports
Anna Czarnecka, Krzysztof Milewski, Radosław Jaźwiec, Magdalena Zielińska
Alterations in brain nitric oxide (NO)/cGMP synthesis contribute to the pathogenesis of hepatic encephalopathy (HE). An increased asymmetrically dimethylated derivative of L-arginine (ADMA), an endogenous inhibitor of NO synthases, was observed in plasma of HE patients and animal models. It is not clear whether changes in brain ADMA reflect its increased local synthesis therefore affecting NO/cGMP pathway, or are a consequence of its increased peripheral blood content. We measured extracellular concentration of ADMA and symmetrically dimethylated isoform (SDMA) in the prefrontal cortex of control and thioacetamide (TAA)-induced HE rats...
September 8, 2016: Neurotoxicity Research
Stefano Catola, Srikanta Dani Kaidala Ganesha, Luca Calamai, Francesco Loreto, Annamaria Ranieri, Mauro Centritto
Dimethylsulfoniopropionate (DMSP) and dimethyl sulphide (DMS) are compounds found mainly in marine phytoplankton and in some halophytic plants. DMS is a globally important biogenic volatile in regulating of global sulfur cycle and planetary albedo, whereas DMSP is involved in the maintenance of plant-environment homeostasis. Plants emit minute amounts of DMS compared to marine phytoplankton and there is a need for hypersensitive analytic techniques to enable its quantification in plants. Solid Phase Micro Extraction from Head Space (HS-SPME) is a simple, rapid, solvent-free and cost-effective extraction mode, which can be easily hyphenated with GC-MS for the analysis of volatile organic compounds...
2016: Frontiers in Plant Science
Mindaugas Mitkus, Gabrielle A Nevitt, Johannis Danielsen, Almut Kelber
Procellariiform or 'tubenosed' seabirds are challenged to find prey and orient over the seemingly featureless oceans. Previous studies have found that life history strategy (burrow vs. surface nesting) was correlated to foraging strategy. Burrow nesters tended to track prey using dimethyl sulphide (DMS), a compound associated with phytoplankton, whereas surface-nesting species did not. Burrow nesters also tended to be smaller and more cryptic, whereas surface nesters were larger with contrasting plumage coloration...
September 2, 2016: Journal of Experimental Biology
S-J Royer, M Galí, A S Mahajan, O N Ross, G L Pérez, E S Saltzman, R Simó
Emission of the trace gas dimethylsulphide (DMS) from the ocean influences the chemical and optical properties of the atmosphere, and the olfactory landscape for foraging marine birds, turtles and mammals. DMS concentration has been seen to vary across seasons and latitudes with plankton taxonomy and activity, and following the seascape of ocean's physics. However, whether and how does it vary at the time scales of meteorology and day-night cycles is largely unknown. Here we used high-resolution measurements over time and depth within coherent water patches in the open sea to show that DMS concentration responded rapidly but resiliently to mesoscale meteorological perturbation...
2016: Scientific Reports
Rodrigo Alonso, Jose Luis Díaz-Díaz, Francisco Arrieta, Francisco Fuentes-Jiménez, Raimundo de Andrés, Pedro Saenz, Gema Ariceta, José I Vidal-Pardo, Fatima Almagro, Rosa Argueso, Pablo Prieto-Matos, José P Miramontes, Xavier Pintó, Johana Rodriguez-Urrego, Leopoldo Perez de Isla, Pedro Mata
BACKGROUND: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder associated with very high levels of cholesterol, accelerated atherosclerosis and very premature death, often secondary to occlusion of the coronary ostia by supravalvular atheroma in untreated individuals. OBJECTIVE: To describe molecular and clinical characteristics of HoFH enrolled at SAFEHEART registry and to evaluate the role of the type of mutation in clinical expression...
July 2016: Journal of Clinical Lipidology
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