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Marsha Maurer, Pamela Browall, Cynthia Phelan, Sandra Sanchez, Kimberlyann Sulmonte, Jane Wandel, Allison Wang
A daily management system (DMS) can be used to implement continuous quality improvement and advance employee engagement. It can empower staff to identify problems in the care environment that impact quality or work flow and to address them on a daily basis. Through a DMS, improvement becomes the work of everyone, every day. The authors of this 2-part series describe their work to develop a DMS. Part 2 describes the implementation and outcomes of the program.
February 21, 2018: Journal of Nursing Administration
Kevin J Sanchez, Chia-Li Chen, Lynn M Russell, Raghu Betha, Jun Liu, Derek J Price, Paola Massoli, Luke D Ziemba, Ewan C Crosbie, Richard H Moore, Markus Müller, Sven A Schiller, Armin Wisthaler, Alex K Y Lee, Patricia K Quinn, Timothy S Bates, Jack Porter, Thomas G Bell, Eric S Saltzman, Robert D Vaillancourt, Mike J Behrenfeld
Biogenic sources contribute to cloud condensation nuclei (CCN) in the clean marine atmosphere, but few measurements exist to constrain climate model simulations of their importance. The chemical composition of individual atmospheric aerosol particles showed two types of sulfate-containing particles in clean marine air masses in addition to mass-based Estimated Salt particles. Both types of sulfate particles lack combustion tracers and correlate, for some conditions, to atmospheric or seawater dimethyl sulfide (DMS) concentrations, which means their source was largely biogenic...
February 19, 2018: Scientific Reports
Yadong Sun, Jiyou Gu, Haiyan Tan, Yanhua Zhang, Pengfei Huo
Starch-based adhesives were prepared by esterification modification with dodecenyl succinic anhydride (DDSA) and polyaryl polymethylene isocyanate (PAPI) as a crosslinking agent. DDSA modified starch (DMS) adhesives could significantly enhance the viscosity and adhesion strength of starch adhesives, making it beneficial to be applied in the field of plywood industry. This paper investigated the physicochemical properties of starch modified by dodecenyl succinic anhydride. Solid content, viscosity, adhesion, structural change and morphological features were characterized in detail...
February 15, 2018: International Journal of Biological Macromolecules
J Hu, X Feng, M Valdearcos, D Lutrin, Y Uchida, S K Koliwad, M Maze
BACKGROUND: Perioperative neurocognitive disorders (PND) result in long-term morbidity and mortality with no effective interventions available. Because interleukin-6 (IL-6), a pro-inflammatory cytokine, is consistently up-regulated by trauma, including after surgery, we determined whether IL-6 is a putative therapeutic target for PND in a mouse model. METHODS: Following institutional approval, adult (12-14 weeks) male C57/Bl6 mice were pretreated with the IL-6 receptor (IL6R) blocking antibody tocilizumab prior to open tibia fracture with internal fixation under isoflurane anaesthesia...
March 2018: British Journal of Anaesthesia
Ijaz Ahmad, Fan Zhang, Junguo Liu, Muhammad Naveed Anjum, Muhammad Zaman, Muhammad Tayyab, Muhammad Waseem, Hafiz Umar Farid
This paper presents a simple bi-level multi-objective linear program (BLMOLP) with a hierarchical structure consisting of reservoir managers and several water use sectors under a multi-objective framework for the optimal allocation of limited water resources. Being the upper level decision makers (i.e., leader) in the hierarchy, the reservoir managers control the water allocation system and tend to create a balance among the competing water users thereby maximizing the total benefits to the society. On the other hand, the competing water use sectors, being the lower level decision makers (i...
2018: PloS One
Arfan Bukhtiar, Zou BingSuo
The doping techniques are often used to modify the properties of semiconductors. Transition metal ion doping in semiconductor can lead to dilute magnetic semiconductors (DMSs), which may initiate some novel properties related to spins. In contrast to the wide band semiconductor ZnO, ZnSe and CdS crystal the transition metal (TM) ion aggregate can be the origin of the ferromagnetic behaviors, which influence their optical properties mainly through the exciton-spin interactions due to their high exciton binding energy...
July 1, 2018: Journal of Nanoscience and Nanotechnology
Ho Ju Yun, Hyun Hee Cho
This cross-sectional study analysed the characteristics of HSDD (hypoactive sexual desire disorder) in Korean women. Two hundred and seventeen women seen for sexual dysfunction were assessed using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Revised (DMS IV-TR) and the Female Sexual Function Index (FSFI). A diagnosis of HSDD was more common in women in their 40 s (56%), who had previously undergone surgery for a feeling of 'wide vagina'. Both too much or too little sexual activity caused HSDD...
February 12, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Antonella Muscella, Carla Vetrugno, Luca Giulio Cossa, Giovanna Antonaci, Amilcare Barca, Sandra Angelica De Pascali, Francesco Paolo Fanizzi, Santo Marsigliante
[This corrects the article DOI: 10.1371/journal.pone.0181114.].
2018: PloS One
Tomohiko Yoshizawa, Makoto Ito, Kenji Doya
The striatum has been shown to play a critical role in reward prediction. It is composed of two neurochemically and anatomically distinct compartments known as the striosomes and the matrix. The striosomes comprise only about 15% of the striatum by volume and are distributed mosaically therein. Accordingly, it has been difficult to identify striosomal neurons in electrophysiological recordings and it has been unclear whether striosomal neurons, which project to midbrain dopaminergic neurons, engage in reward prediction...
January 2018: ENeuro
P P A Oliveira, R R S Corte, S L Silva, P H M Rodriguez, L S Sakamoto, A F Pedroso, R R Tullio, A Berndt
This study was carried out to evaluate the effects of four levels of intensification of grazing systems: 1) degraded pasture - DP; 2) irrigated pasture with high stocking rate - IHS; 3) dryland pasture with high stocking rate - DHS; 4) dryland pasture with moderate stocking rate - DMS; on growth, muscle development and meat quality of Nellore steers (271±2.2kg of live body weight - BW; 15months old) during two consecutive periods (17 and 15months). The final BW, the average daily BW gain, the hot carcass weight and the dress percentage were greater (P<0...
February 7, 2018: Meat Science
Lucheng Li, Guoren Xu, Huarong Yu, Jia Xing
Dynamic membranes (DMs) have been of great interest in recent years because they can reduce energy consumption and costs during wastewater treatment. Dynamic membranes are a promising technology for the removal of low-density, non-degradable micro-particles, such as plastics, which are an increasingly prevalent wastewater contaminant. These micro-particles are not easily removed via conventional sedimentation and result in increased operation and maintenance costs in downstream unit processes. In this study, DMs were formed on a 90 μm supporting mesh through filtration of a synthetic wastewater...
January 29, 2018: Science of the Total Environment
R L Macdonald, M S Grover, T E Schwartzentruber, M Panesi
This work presents the analysis of non-equilibrium energy transfer and dissociation of nitrogen molecules (N2(Σg+1)) using two different approaches: the direct molecular simulation (DMS) method and the coarse-grain quasi-classical trajectory (CG-QCT) method. The two methods are used to study thermochemical relaxation in a zero-dimensional isochoric and isothermal reactor in which the nitrogen molecules are heated to several thousand degrees Kelvin, forcing the system into strong non-equilibrium. The analysis considers thermochemical relaxation for temperatures ranging from 10 000 to 25 000 K...
February 7, 2018: Journal of Chemical Physics
David C Tack, Yin Tang, Laura E Ritchey, Sarah M Assmann, Philip C Bevilacqua
The secondary structure of an RNA is often implicit to its function. Recently, various high-throughput RNA structure probing techniques have been developed to elucidate important RNA structure-function relationships genome-wide. These techniques produce unwieldy experimental data sets that require evaluation with unique computational pipelines. Herein, we present StructureFold2, a user-friendly set of analysis tools that makes precise data processing and detailed downstream analyses of such data sets both available and practical...
February 1, 2018: Methods: a Companion to Methods in Enzymology
Wen Tian, Yongsheng Li, Jinghua Zhang, Jijun Li, Jinghua Gao
Osteosarcoma (OS) is a common primary malignancy in children and adolescents with relative high survival rate after chemotherapy. While, the toxicity of chemotherapy and personalized different response to chemotherapy makes it difficult for the selection of therapeutics and improvement of diagnosis. In this study, we conducted a combined analysis of two types of microarray datasets (gene expression and DNA methylation) from the Gene Expression Omnibus (GEO). Differential methylation sites (DMS) were identified by the IMA package and differential expression genes (DEGs) were screened out via the limma package...
January 30, 2018: Gene
Hong Cui, Tie-Ling Li, Hai-Feng Guo, Jia-Liang Wang, Ping Xue, Ying Zhang, Jing-Hui Fan, Zhi-Ping Li, Yue-Juan Gao
A novel module-search algorithm method was used to screen for potential signatures and investigate the molecular mechanisms of inhibiting hepatocellular carcinoma (HCC) growth following treatment with silymarin (SM). The modules algorithm was used to identify the modules via three major steps: i) Seed gene selection; ii) module search by seed expansion and entropy minimization; and iii) module refinement. The statistical significance of modules was computed to select the differential modules (DMs), followed by the identification of core modules using the attract method...
January 2018: Oncology Letters
Artur Mardyukov, Peter R Schreiner
The large number and amounts of volatile organosulfur compounds emitted to the atmosphere and the enormous variety of their reactions in various oxidation states make experimental measurements of even a small fraction of them a daunting task. Dimethyl sulfide (DMS) is a product of biological processes involving marine phytoplankton, and it is estimated to account for approximately 60% of the total natural sulfur gases released to the atmosphere. Ocean-emitted DMS has been suggested to play a role in atmospheric aerosol formation and thereby cloud formation...
February 2, 2018: Accounts of Chemical Research
David R Coghill, Tobias Banaschewski, Caleb Bliss, Brigitte Robertson, Alessandro Zuddas
BACKGROUND: SPD489-404 was the first 2-year safety study of lisdexamfetamine dimesylate in the treatment of attention-deficit/hyperactivity disorder in children and adolescents. In accordance with advice from the European Medicines Agency, assessment of cognitive function was a predefined safety outcome in SPD489-404. OBJECTIVE: The objective of this study was to assess cognitive function over 2 years in study SPD489-404, using the Cambridge Neuropsychological Test Automated Battery (CANTAB)...
January 30, 2018: CNS Drugs
Marsha Maurer, Elena Canacari, Kimberly Eng, Jane Foley, Cynthia Phelan, Kimberlyann Sulmonte, Jane Wandel
A daily management system (DMS) can be used to implement continuous quality improvement and advance employee engagement. It can empower staff to identify problems in the care environment that impact quality or workflow and to address them on a daily basis. Through DMS, improvement becomes the work of everyone, every day. The authors of this 2-part series describe their work to develop a DMS. Part 1 describes the background and organizing framework of the program.
January 27, 2018: Journal of Nursing Administration
Xuan Li, Kailyn Witonsky, Olivia M Lofaro, Felicia Surjono, Jianjun Zhang, Jennifer M Bossert, Yavin Shaham
Relapse to methamphetamine (Meth) seeking progressively increases after withdrawal from drug self-administration (incubation of Meth craving). We previously demonstrated a role of dorsomedial striatum (DMS) dopamine D1 receptors (D1Rs) in this incubation. Here, we studied the role of afferent glutamatergic projections into DMS and local D1R-glutamate interaction in this incubation in male rats.We first measured projection-specific activation on day 30 relapse test by using CTb (retrograde tracer) + Fos (activity marker) double-labeling in projection areas...
January 25, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Tianming Ren, Runzhi Li, Xiangjun Meng, J Paul Fawcett, Dong Sun, Jingkai Gu
Eptifibatide is a therapeutic cyclic peptide with poor collision-induced dissociation (CID) efficiency for multiple reaction monitoring (MRM), which limits the development of a traditional liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioassay with MRM. In this study, a method combining differential mobility spectrometry (DMS) with liquid chromatography-multiple ion monitoring (LC-DMS-MIM) was developed for the quantitation of eptifibatide in rat plasma. After solid phase extraction (SPE) of 100 μL plasma on an Oasis® HLB cartridge, the analyte and I...
January 11, 2018: Journal of Pharmaceutical and Biomedical Analysis
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