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https://www.readbyqxmd.com/read/28088048/disclosure-management-behaviors-in-korean-adults-with-well-controlled-epilepsy-their-relation-to-perception-of-stigma
#1
Sang-Ahm Lee, Byung-In Lee
PURPOSE: In spite of the fact that epilepsy is a concealable stigmatized identity, there is little evidence pertaining to disclosure management in adults living with epilepsy. We determined the factors contributing to disclosure management strategies in adults living with well-controlled epilepsy. METHODS: This was a cross-sectional multicenter study. Korean adults whose seizures had remitted for at least one year participated in this study. Using statistical analyses, we determined whether disclosure management behaviors measured using the Disclosure Management Scale (DMS) were related to demographic, clinical, and psychosocial variables...
January 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28077805/spin-exciton-interaction-and-related-micro-photoluminescence-spectra-of-znse-mn-dms-nanoribbon
#2
Lipeng Hou, Weichang Zhou, Bingsuo Zou, Yu Zhang, Junbo Han, Xinxin Yang, Zhihong Gong, Jingbo Li, Sishen Xie, Lijie Shi
For their spintronic applications the magnetic and optical properties of diluted magnetic semiconductors (DMS) have been studied widely. However, the exact relationships between their magnetic interactions and optical emission behaviors in DMS are not well understood yet due to their complicated microstructural and compositional characters from different growth and preparation techniques. Manganese (Mn) doped ZnSe nanoribbons with high quality were obtained by using the chemical vapor deposition (CVD) method...
January 12, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28068310/visualizing-the-secondary-and-tertiary-architectural-domains-of-lncrna-repa
#3
Fei Liu, Srinivas Somarowthu, Anna Marie Pyle
Long noncoding RNAs (lncRNAs) are important for gene expression, but little is known about their structures. RepA is a 1.6-kb mouse lncRNA comprising the same sequence as the 5' region of Xist, including A and F repeats. It has been proposed to facilitate the initiation and spread of X-chromosome inactivation, although its exact role is poorly understood. To gain insight into the molecular mechanism of RepA and Xist, we determined a complete phylogenetically validated secondary-structural map of RepA through SHAPE and DMS chemical probing of a homogeneously folded RNA in vitro...
January 9, 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/28062527/lessons-from-the-organisation-of-the-uk-medical-services-deployed-in-support-of-operation-telic-iraq-and-operation-herrick-afghanistan
#4
Martin C M Bricknell, M Nadin
This paper provides the definitive record of the UK Defence Medical Services (DMS) lessons from the organisation of medical services in support of Operation (Op) TELIC (Iraq) and Op HERRICK (Afghanistan). The analysis involved a detailed review of the published academic literature, internal post-operational tour reports and post-tour interviews. The list of lessons was reviewed through three Military Judgement Panel cycles producing the single synthesis 'the golden thread' and eight 'silver bullets' as themes to institutionalise the learning to deliver the golden thread...
January 6, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28056824/the-emerging-landscape-of-dynamic-dna-methylation-in-early-childhood
#5
Cheng-Jian Xu, Marc Jan Bonder, Cilla Söderhäll, Mariona Bustamante, Nour Baïz, Ulrike Gehring, Soesma A Jankipersadsing, Pieter van der Vlies, Cleo C van Diemen, Bianca van Rijkom, Jocelyne Just, Inger Kull, Juha Kere, Josep Maria Antó, Jean Bousquet, Alexandra Zhernakova, Cisca Wijmenga, Isabella Annesi-Maesano, Jordi Sunyer, Erik Melén, Yang Li, Dirkje S Postma, Gerard H Koppelman
BACKGROUND: DNA methylation has been found to associate with disease, aging and environmental exposure, but it is unknown how genome, environment and disease influence DNA methylation dynamics in childhood. RESULTS: By analysing 538 paired DNA blood samples from children at birth and at 4-5 years old and 726 paired samples from children at 4 and 8 years old from four European birth cohorts using the Illumina Infinium Human Methylation 450 k chip, we have identified 14,150 consistent age-differential methylation sites (a-DMSs) at epigenome-wide significance of p < 1...
January 5, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28048175/su-f-p-04-implementation-of-dose-monitoring-software-successes-and-pitfalls
#6
J Och
PURPOSE: to successfully install a dose monitoring software (DMS) application to assist in CT protocol and dose management. METHODS: Upon selecting the DMS, we began our implementation of the application. A working group composed of Medical Physics, Radiology Administration, Information Technology, and CT technologists was formed. On-site training in the application was supplied by the vendor. The decision was made to apply the process for all the CT protocols on all platforms at all facilities...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047796/we-de-201-01-best-in-physics-therapy-a-fast-multi-target-inverse-treatment-planning-strategy-optimizing-dosimetric-measures-for-high-dose-rate-hdr-brachytherapy
#7
C Guthier, A Damato, A Viswanathan, J Hesser, R Cormack
PURPOSE: Inverse treatment planning (ITP) for interstitial HDR brachytherapy of gynecologic cancers seeks to maximize coverage of the clinical target volumes (tumor and vagina) while respecting dose-volume-histogram related dosimetric measures (DMs) for organs at risk (OARs). Commercially available ITP tools do not support DM-based planning because it is computationally too expensive to solve. In this study we present a novel approach that allows fast ITP for gynecologic cancers based on DMs for the first time...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028593/quantification-of-dimethylsulfoniopropionate-dmsp-in-acropora-spp-of-reef-building-coral-using-mass-spectrometry-with-deuterated-internal-standard
#8
Hilton B Swan, Elisabeth S M Deschaseaux, Graham B Jones, Bradley D Eyre
Dimethylsulfoniopropionate (DMSP) in scleractinian coral is usually analysed indirectly as dimethylsulfide (DMS) using gas chromatography (GC) with a sulfur-specific detector. We developed a headspace GC method for mass spectral analysis of DMSP in branching coral where hexa-deuterated DMSP (d 6 -DMSP) was added to samples and standards to optimise the analytical precision and quantitative accuracy. Using this indirect HS-GC-MS method, we show that common coral sample handling techniques did not alter DMSP concentrations in Acropora aspera and that endogenous DMS was insignificant compared to the store of DMSP in A...
December 27, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28000890/combined-analysis-of-gene-expression-mirna-expression-and-dna-methylation-profiles-of-osteosarcoma
#9
Wenpeng Zhang, Shiliang Han, Kang Sun
Osteosarcoma (OS) is a common primary malignancy in children and adolescents with relative high survival rate after chemotherapy. While the toxicity of chemotherapy and personalized different response to chemotherapy makes it difficult for the selection of therapeutics and improvement of diagnosis. In this study, we conducted a combined analysis of three types of microarray datasets (gene expression, microRNA (miRNA) expression and DNA methylation) from the Gene Expression Omnibus (GEO). The differential expression genes (DEGs) and miRNAs (DEMI) were screened out via the limma package and differential methylation sites (DMS) were identified by the IMA package...
February 2017: Oncology Reports
https://www.readbyqxmd.com/read/27995864/detection-of-mycobacteria-by-voc-analysis-of-in-vitro-cultures-using-differential-ion-mobility-spectrometry-dms
#10
Roman Purkhart, Gunther Becher, Petra Reinhold, Heike U Köhler
Differential ion mobility spectrometry (DMS) is an analytical technique to detect volatile organic compounds (VOCs) in gaseous samples at very low concentration ranges from ppb to ppt. The aim of this study was to investigate whether VOC analysis by DMS is capable of detecting Mycobacterium avium subspecies paratuberculosis (MAP). Headspaces of in vitro cultures of two different MAP strains at 1, 2, 3, 4 and 6 weeks after inoculation (each at two dilutions) were analyzed with DMS in comparison to control samples without viable bacteria ([i] blank medium, [ii] medium inoculated with heat-inactivated MAP, and [iii] sterile-filtered MAP culture broth)...
December 19, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27993080/cdom-sources-and-photobleaching-control-quantum-yields-for-oceanic-dms-photolysis
#11
Martí Galí, David J Kieber, Cristina Romera-Castillo, Joanna D Kinsey, Emmanuel Devred, Gonzalo L Pérez, George R Westby, Cèlia Marrasé, Marcel Babin, Maurice Levasseur, Carlos M Duarte, Susana Agustí, Rafel Simó
Photolysis is a major removal pathway for the biogenic gas dimethylsulfide (DMS) in the surface ocean. Here we tested the hypothesis that apparent quantum yields (AQY) for DMS photolysis varied according to the quantity and quality of its photosensitizers, chiefly chromophoric dissolved organic matter (CDOM) and nitrate. AQY compiled from the literature and unpublished studies ranged across 3 orders of magnitude at the 330 nm reference wavelength. The smallest AQY(330) were observed in coastal waters receiving major riverine inputs of terrestrial CDOM (0...
December 20, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27983615/peripheral-inflammatory-markers-contributing-to-comorbidities-in-autism
#12
Martha Cecilia Inga Jácome, Lilia Maria Morales Chacòn, Hector Vera Cuesta, Carlos Maragoto Rizo, Mabel Whilby Santiesteban, Lesyanis Ramos Hernandez, Elena Noris García, Maria Elena González Fraguela, Caridad Ivette Fernandez Verdecia, Yamilé Vegas Hurtado, Dario Siniscalco, Carlos Alberto Gonçalves, Maria de Los Angeles Robinson-Agramonte
This study evaluates the contribution of peripheral biomarkers to comorbidities and clinical findings in autism. Seventeen autistic children and age-matched typically developing (AMTD), between three to nine years old were evaluated. The diagnostic followed the Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DMS-IV) and the Childhood Autism Rating Scale (CARS) was applied to classify the severity. Cytokine profile was evaluated in plasma using a sandwich type ELISA. Paraclinical events included electroencephalography (EEG) record...
December 14, 2016: Behavioral Sciences
https://www.readbyqxmd.com/read/27980115/role-of-dorsomedial-striatum-neuronal-ensembles-in-incubation-of-methamphetamine-craving-after-voluntary-abstinence
#13
Daniele Caprioli, Marco Venniro, Michelle Zhang, Jennifer M Bossert, Brandon L Warren, Bruce T Hope, Yavin Shaham
: We recently developed a rat model of incubation of methamphetamine craving after choice-based voluntary abstinence. Here, we studied the role of dorsolateral and dorsomedial striatum (DLS, DMS) in this incubation.We trained rats to self-administer palatable food pellets (6 days, 6-h/d) and methamphetamine (12 days, 6-h/d). We then assessed relapse to methamphetamine seeking under extinction conditions after 1 and 21 abstinence days. Between tests, the rats underwent voluntary abstinence (using a discrete choice procedure between methamphetamine and food; 20 trials/day) for 19 days...
December 15, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27973723/influence-of-cognitive-function-on-quality-of-life-in-anorexia-nervosa-patients
#14
Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Yukio Tada, Yukiko Tomioka, Shinya Watanabe, Masatoshi Inoshita, Makoto Kinoshita, Masashi Ohta, Tetsuro Ohmori
AIMS: The purpose of this study was to elucidate determinants of quality of life (QOL) in anorexia nervosa (AN) patients. METHODS: Twenty-one female patients with AN participated in the study. QOL was assessed with the 36-Item Short Form Health Survey (SF-36), and cognitive function was evaluated using the Wisconsin Card Sorting Test Keio version (KWCST), the Rey Complex Figure Test (RCFT) and the Social Cognition Screening Questionnaire. Clinical symptoms were evaluated with the Beck Depression Inventory-II (BDI- II), the State-Trait Anxiety Inventory-Form JYZ (STAI-JYZ) and the Maudsley Obsessive Compulsive Inventory...
December 14, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27966223/prevalence-of-sleep-disturbances-and-their-associations-with-demographic-and-clinical-characteristics-and-quality-of-life-in-older-adults-in-macao
#15
Bernice O C Lam Nogueira, Lu Li, Li-Rong Meng, Gabor S Ungvari, Brent P Forester, Helen F K Chiu, Kenny C F Kuok, Linda Tran, Zhao-Min Liu, Yu-Tao Xiang
PURPOSE: To examine the prevalence of sleep disturbances (difficulty initiating sleep [DIS], difficulty maintaining sleep [DMS], and early morning awakening [EMA]), their socio-demographic and clinical correlates, and quality of life (QOL) in older adults in Macao. DESIGN AND METHODS: Four hundred fifty-one subjects were interviewed using standardized instruments. FINDINGS: The prevalence of at least one type of sleep disturbance was 38.1%; the figures of DIS, DMS, and EMA were 18...
December 14, 2016: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/27960545/differential-mobility-spectrometry-combined-with-multiple-ion-monitoring-for-bioanalysis-of-disulfide-bonded-peptides-with-inefficient-collision-induced-dissociation-fragmentation
#16
Yuan-Qing Xia, Eugene Ciccimaro, Naiyu Zheng, Mingshe Zhu
AIM: It is challenging to develop a multiple reaction monitoring (MRM) method for some disulfide-bonded peptides with inefficient collision-induced dissociation fragmentation. This study describes a new methodology using differential mobility spectrometry (DMS) combined with multiple ion monitoring (MIM) to enhance bioanalytical sensitivity for sunflower trypsin inhibitor. RESULTS: By combining DMS with MIM to monitor the intact precursor ion in Q1 and Q3 MS analyzers, a lower limit of quantitation at 0...
January 2017: Bioanalysis
https://www.readbyqxmd.com/read/27940294/long-term-performance-and-bacterial-community-dynamics-in-biocovers-for-mitigating-methane-and-malodorous-gases
#17
Eun-Hee Lee, Kyung-Eun Moon, Kyung-Suk Cho
The long-term performance of lab-scale biocovers for the simulation of engineered landfill cover soils was evaluated. Methane (CH4), trimethylamine (TMA), and dimethyl sulfide (DMS) were introduced into the biocovers as landfill gases for 134 days and the removal performance was evaluated. The biocover systems were capable of simultaneously removing methane, TMA, and DMS. Methane was mostly eliminated in the top layer of the systems, while TMA and DMS were removed in the bottom layer. Overall, the methane removal capacity and efficiency were 224...
January 20, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/27906902/comparison-of-transcriptome-between-type-2-diabetes-mellitus-and-impaired-fasting-glucose
#18
Ying Cui, Wen Chen, Jinfeng Chi, Lei Wang
BACKGROUND The aim of this study was to compare the transcriptome between impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM), and further research their molecular mechanisms. MATERIAL AND METHODS The original microarray GSE21321, including miRNA and mRNA expression profiles, was downloaded from the GEO database. Data preprocessing was processed by limma package, and differentially expressed genes (DGs) and miRNA (DMs) were screened. Then, the regulatory relationships among miRNA, TF, and genes were screened and the regulatory network was constructed...
December 1, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27899588/a-high-throughput-approach-to-profile-rna-structure
#19
Riccardo Delli Ponti, Stefanie Marti, Alexandros Armaos, Gian Gaetano Tartaglia
Here we introduce the Computational Recognition of Secondary Structure (CROSS) method to calculate the structural profile of an RNA sequence (single- or double-stranded state) at single-nucleotide resolution and without sequence length restrictions. We trained CROSS using data from high-throughput experiments such as Selective 2'-Hydroxyl Acylation analyzed by Primer Extension (SHAPE; Mouse and HIV transcriptomes) and Parallel Analysis of RNA Structure (PARS; Human and Yeast transcriptomes) as well as high-quality NMR/X-ray structures (PDB database)...
November 28, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27890777/psychological-wellbeing-in-survivors-of-cardiac-arrest-and-its-relationship-to-neurocognitive-function
#20
Siân E Davies, Megan Rhys, Sarah Voss, Rosemary Greenwood, Matthew Thomas, Jonathan R Benger
OBJECTIVE: To characterise psychological wellbeing in survivors of out-of-hospital cardiac arrest (OHCA), and examine its relationship to cognitive function. PATIENTS: Forty-one highly functioning cardiac arrest survivors were drawn from the follow-up cohort of a randomised controlled trial of initial airway management in OHCA (ISRCTN:18528625). DESIGN: Psychological wellbeing was assessed with a self-report questionnaire (the Depression Anxiety and Stress Scale; DASS) and cognitive function was examined using the Delayed Matching to Samples (DMS) test from the Cambridge Neuropsychological Test Automated Battery (CANTAB)...
February 2017: Resuscitation
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