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https://www.readbyqxmd.com/read/29793176/non-ldl-dyslipidemia-is-prevalent-in-the-young-and-determined-by-lifestyle-factors-and-age-the-lifelines-cohort
#1
Jeroen K de Vries, Jan W Balder, Michelle J Pena, Petra Denig, Andries J Smit
BACKGROUND AND AIMS: Non-LDL dyslipidemia (NLD) confers cardiovascular risk, and prevalence rates appear to be high in elderly populations. Small cohorts have identified several lifestyle, anthropometric, and medical factors associated with NLD. We aimed to assess sex- and age-specific prevalence of NLD in a contemporary population cohort (n = 167 729), and to identify independent determinants of NLD, focusing on lifestyle, anthropometric, and medical factors. METHODS: The prevalence of NLD was assessed per 10-year age intervals in adults without cardiovascular disease not using lipid-modifying drugs from the Dutch LifeLines cohort...
May 21, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29793054/bacillus-clausii-inhibits-bone-loss-by-skewing-treg-th17-cell-equilibrium-in-postmenopausal-osteoporotic-mice-model
#2
Hamid Y Dar, Subhashis Pal, Prashant Shukla, Pradyumna K Mishra, Geetanjali B Tomar, Naibedya Chattopadhyay, Rupesh K Srivastava
OBJECTIVES: Postmenopausal osteoporosis is one of most commonly occurring skeletal diseases leading to bone loss and fragility. Probiotics have been associated with various immunomodulatory properties and thus can be exploited to enhance bone health. In the present study, we report, to our knowledge for the first time, that oral administration of Bacillus clausii (BC) in postmenopausal osteoporotic (OVX) mice model enhances bone health. METHODS: BC was selected as probiotic of choice due to its established immunomodulatory properties...
March 20, 2018: Nutrition
https://www.readbyqxmd.com/read/29792555/vaccine-hesitancy-among-caregivers-and-association-with-childhood-vaccination-timeliness-in-addis-ababa-ethiopia
#3
Nina B Masters, Yemesrach A Tefera, Abram L Wagner, Matthew L Boulton
INTRODUCTION: Vaccines are vital to reducing childhood mortality, and prevent an estimated 2 to 3 million deaths annually which disproportionately occur in the developing world. Overall vaccine coverage is typically used as a metric to evaluate the adequacy of vaccine program performance, though it does not account for untimely administration, which may unnecessarily prolong children's susceptibility to disease. This study explored a hypothesized positive association between increasing vaccine hesitancy and untimeliness of immunizations administered under the Expanded Program on Immunization (EPI) in Addis Ababa, Ethiopia...
May 24, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29792500/the-perceived-invalidation-of-emotion-scale-pies-development-and-psychometric-properties-of-a-novel-measure-of-current-emotion-invalidation
#4
Melissa J Zielinski, Jennifer C Veilleux
Emotion invalidation is theoretically and empirically associated with mental and physical health problems. However, existing measures of invalidation focus on past (e.g., childhood) invalidation and/or do not specifically emphasize invalidation of emotion. In this article, the authors articulate a clarified operational definition of emotion invalidation and use that definition as the foundation for development of a new measure of current perceived emotion invalidation across a series of five studies. Study 1 was a qualitative investigation of people's experiences with emotional invalidation from which we generated items...
May 24, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29792488/asian-americans-and-materialism-exploring-the-phenomenon-and-its-why-and-when
#5
Jia Wei Zhang
OBJECTIVES: Consumer values, including but not limited to materialism, have received much less attention than other topics within research on Asian Americans. METHODS: Across 3 studies (N = 6,955), the author explored the difference between Asian Americans and White/European Americans on materialism, and the mediating and moderating mechanisms. RESULTS: Studies 1a-1c found Asian Americans, compared to White/European Americans, more strongly endorsed materialistic values...
May 24, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29792314/severe-and-predominantly-active-atopic-eczema-in-adulthood-and-long-term-risk-of-cardiovascular-disease-population-based-cohort-study
#6
Richard J Silverwood, Harriet J Forbes, Katrina Abuabara, Anna Ascott, Morten Schmidt, Sigrún A J Schmidt, Liam Smeeth, Sinéad M Langan
OBJECTIVE: To investigate whether adults with atopic eczema are at an increased risk of cardiovascular disease and whether the risk varies by atopic eczema severity and condition activity over time. DESIGN: Population based matched cohort study. SETTING: UK electronic health records from the Clinical Practice Research Datalink, Hospital Episode Statistics, and data from the Office for National Statistics, 1998-2015. PARTICIPANTS: Adults with a diagnosis of atopic eczema, matched (on age, sex, general practice, and calendar time) to up to five patients without atopic eczema...
May 23, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29792181/six-underlying-health-conditions-strongly-influence-mortality-based-on-pneumonia-severity-in-an-ageing-population-of-japan-a-prospective-cohort-study
#7
Sugihiro Hamaguchi, Motoi Suzuki, Kota Sasaki, Masahiko Abe, Takao Wakabayashi, Eiichiro Sando, Makito Yaegashi, Shimpei Morimoto, Norichika Asoh, Naohisa Hamashige, Masahiro Aoshima, Koya Ariyoshi, Konosuke Morimoto
BACKGROUND: Mortality prediction of pneumonia by severity scores in patients with multiple underlying health conditions has not fully been investigated. This prospective cohort study is to identify mortality-associated underlying health conditions and to analyse their influence on severity-based pneumonia mortality prediction. METHODS: Adult patients with community-acquired pneumonia or healthcare-associated pneumonia (HCAP) who visited four community hospitals between September 2011 and January 2013 were enrolled...
May 23, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29792069/maternal-nutrition-and-the-developmental-origins-of-osteoporosis-in-offspring-potential-mechanisms-and-clinical-implications
#8
Jia Zheng, Qianyun Feng, Sheng Zheng, Xinhua Xiao
Osteoporosis, the most frequent metabolic disorder of bone, is a complex disease with a multifactorial origin that is influenced by genes and environments. However, the pathogenesis of osteoporosis has not been fully elucidated. The theory of "Developmental Origins of Health and Disease" indicates that early life environment exposure determines the risks of cardiometabolic diseases in adulthood. However, investigations into the effects of maternal nutrition and nutrition exposure during early life on the development of osteoporosis are limited...
January 1, 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29791940/global-neurology-navigating-career-possibilities
#9
Nicoline Schiess, Deanna Saylor, Joseph Zunt
Neurology has not typically been associated with international relief work; however, with the growth of chronic cardiovascular disease and stroke associated with unhealthy eating and sedentary ways, the appearance of "new" neurologic diseases, such as the Zika and West Nile viruses, and the high numbers of seizure disorders resulting from neuroinfectious diseases, more opportunities are arising for international and globally oriented neurologists. Multiple opportunities exist for developing a global clinician-educator career pathway, including private institutions, nongovernmental organizations, government-funded opportunities such as Medical Education Partnership Initiative, Fogarty and Fulbright Scholarships, and the American Academy of Neurology's Global Health Section...
April 2018: Seminars in Neurology
https://www.readbyqxmd.com/read/29791905/disparities-in-chronic-kidney-disease-prevalence-among-males-and-females-in-195-countries-analysis-of-the-global-burden-of-disease-2016-study
#10
Boris Bikbov, Norberto Perico, Giuseppe Remuzzi
BACKGROUND: Chronic kidney disease (CKD) imposes a substantial burden on health care systems. There are some especially vulnerable groups with a high CKD burden, one of which is women. We performed an analysis of gender disparities in the prevalence of all CKD stages and renal replacement therapy (defined as impaired kidney function [IKF]) in 195 countries. METHODS: We used estimates produced by the Global Burden of Disease (GBD) Study 2016 revision using a Bayesian-regression analytic tool, DisMoD-MR 2...
May 23, 2018: Nephron
https://www.readbyqxmd.com/read/29791750/tiled-array-based-sequencing-identifies-enrichment-of-loss-of-function-variants-in-the-highly-homologous-filaggrin-gene-in-african-american-children-with-severe-atopic-dermatitis
#11
Mary Elizabeth Mathyer, Ashley M Quiggle, X F Colin C Wong, Simon L I J Denil, Monique G Kumar, Heather M Ciliberto, Susan J Bayliss, John E Common, Cristina de Guzman Strong
Filaggrin (FLG) loss of function (LOF) variants are a major risk factor for the common inflammatory skin disease, atopic dermatitis (AD), and are often population-specific. African American (AA) children are disproportionately affected with AD, often later developing asthma and/or allergic rhinitis and comprise an atopy health disparity group for which the role of FLG LOF is not well known. Discovery of FLG LOF using exome sequencing is challenging given the known difficulties for accurate short-read alignment to FLG's high homology repeat variation...
May 23, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29791726/building-capacity-in-health-and-education-systems-to-deliver-interventions-that-strengthen-early-child-development
#12
Milagros Nores, Camila Fernandez
Building capacity within health and education systems of low- and middle-income countries in order to deliver high-quality early childhood services requires coordinated efforts across sectors, effective governance, sufficient funding, an adequate workforce, reliable data systems, and continuous monitoring, evaluation, and improvement cycles; it also requires partnerships with the private sector, communities, and parents. In addition, building capacity requires leadership, innovation of strategies to fit into existing structures, evidence-based intervention models, and effective partnerships that help make interventions more culturally relevant, help finance them, and help create institutional long-term support and sustainability for them...
May 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29791642/integrative-review-of-literature-nursing-care-to-aged-people-with-hiv
#13
Arayana Gomes da Silva, Viviane Siqueira Cavalcanti, Tâmyssa Simões Dos Santos, Gabriela Rodrigues Bragagnollo, Karen da Silva Santos, Ivanilde Miciele da Silva Santos, Kristiana Cerqueira Mousinho, Cinira Magali Fortuna
OBJECTIVE: To identify evidences in scientific Brazilian literature on nursing care to aged people with HIV. METHOD: Integrative review of literature from databases: Latin American and Caribbean Literature on Health Sciences (LILACS), Scientific Eletronic Library Online (SciELO), Cochrane and the Nursing Database (BDENF). The applied inclusion criteria were publications that were fully available from 2001 to 2015 and answered to the guiding question of this study...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791501/stillbirths-in-urban-guinea-bissau-a-hospital-and-community-based-study
#14
Morten Bjerregaard-Andersen, Najaaraq Lund, Anne Sofie Pinstrup Joergensen, Frida Starup Jepsen, Holger Werner Unger, Mama Mane, Amabelia Rodrigues, Staffan Bergström, Christine Stabell Benn
BACKGROUND: Stillbirth rates remain high in many low-income settings, with fresh (intrapartum) stillbirths accounting for a large part due to limited obstetrical care. We aimed to determine the stillbirth rate and identify potentially modifiable factors associated with stillbirth in urban Guinea-Bissau. METHODS: The study was carried out by the Bandim Health Project (BHP), a Health and Demographic Surveillance System site in the capital Bissau. We assessed stillbirth rates in a hospital cohort consisting of all deliveries at the maternity ward at the National Hospital Simão Mendes (HNSM), and in a community cohort, which only included women from the BHP area...
2018: PloS One
https://www.readbyqxmd.com/read/29790775/dental-periodontal-and-salivary-conditions-in-diabetic-children-associated-with-metabolic-control-variables-and-nutritional-plan-adherence
#15
C Y Díaz Rosas, E Cárdenas Vargas, J E Castañeda-Delgado, L A Aguilera-Galaviz, M C Aceves Medina
AIM: Diabetes mellitus is a chronic disease that has manifestations other than alterations in endocrine regulation or in metabolic pathways. Several diseases of the oral cavity have been associated with diabetes mellitus type 1 and 2 in young people according to their evolution. Scarce information exists regarding the role of diabetes and its association with the oral health status in paediatric diabetic patients. The aims of the study were to assess the quality of saliva, saliva acidogenicity, dental caries experience, fluorosis and periodontal status in diabetic patients and to evaluate their relationship with metabolic control variables and nutritional plan adherence...
June 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29790393/assistive-technology-policy-a-position-paper-from-the-first-global-research-innovation-and-education-on-assistive-technology-great-summit
#16
Malcolm MacLachlan, David Banes, Diane Bell, Johan Borg, Brian Donnelly, Michael Fembek, Ritu Ghosh, Rosie Gowran, Emma Hannay, Diana Hiscock, Evert-Jan Hoogerwerf, Tracey Howe, Friedbert Kohler, Natasha Layton, Siobhán Long, Hasheem Mannan, Gubela Mji, Thomas Odera Ongolo, Katherine Perry, Cecilia Pettersson, Jessica Power, Vinicius Delgado Ramos, Lenka Slepičková, Emma Smith, Kiu Tay-Teo, Priscille Geiser, Hilary Hooks
Increased awareness, interest and use of assistive technology (AT) presents substantial opportunities for many citizens to become, or continue being, meaningful participants in society. However, there is a significant shortfall between the need for and provision of AT, and this is patterned by a range of social, demographic and structural factors. To seize the opportunity that assistive technology offers, regional, national and sub-national assistive technology policies are urgently required. This paper was developed for and through discussion at the Global Research, Innovation and Education on Assistive Technology (GREAT) Summit; organized under the auspices of the World Health Organization's Global Collaboration on Assistive Technology (GATE) program...
May 23, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29789709/consumption-of-green-tea-but-not-coffee-is-associated-with-the-oral-health-related-quality-of-life-among-an-older-japanese-population-kyoto-kameoka-cross-sectional-study
#17
Hinako Nanri, Yosuke Yamada, Aya Itoi, Emi Yamagata, Yuya Watanabe, Tsukasa Yoshida, Motoko Miyake, Heiwa Date, Kazuko Ishikawa-Takata, Mitsuyoshi Yoshida, Takeshi Kikutani, Misaka Kimura
BACKGROUND/OBJECTIVES: The consumption of both green tea and coffee is known to induce positive health effects; however, it remains unclear whether there is an association between the consumption of these beverages and oral health-related quality of life (OHRQoL). Thus, the present study investigated the relationship between the consumption of green tea and coffee and OHRQoL. SUBJECTS/METHODS: We analyzed cross-sectional baseline data in 2012. The subjects were 7514 Japanese participants (3563 men, 3951 women; ≥65 years of age)...
May 23, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29789369/-wolbachia-w-stri-blocks-zika-virus-growth-at-two-independent-stages-of-viral-replication
#18
M J Schultz, A L Tan, C N Gray, S Isern, S F Michael, H M Frydman, J H Connor
Mosquito-transmitted viruses are spread globally and present a great risk to human health. Among the many approaches investigated to limit the diseases caused by these viruses are attempts to make mosquitos resistant to virus infection. Coinfection of mosquitos with the bacterium Wolbachia pipientis from supergroup A is a recent strategy employed to reduce the capacity for major vectors in the Aedes mosquito genus to transmit viruses, including dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV)...
May 22, 2018: MBio
https://www.readbyqxmd.com/read/29789275/perceived-expressed-emotion-emotional-and-behavioral-problems-and-self-esteem-in-obese-adolescents-a-case-control-study
#19
Merve Çolpan, Şafak Eray, Erdal Eren, Ayşe Pınar Vural
OBJECTIVE: Obesity is a chronic disease which causes medical and psychiatric complications. Family climate is also a critical factor in the presence and treatment of obesity and comorbid psychiatric disorders. In our study, perceived expressed emotion (EE), psychopathology, self-esteem and emotional and behavioural problems among obese adolescents will be investigated by comparison with their non-obese peers. METHODS: This study was carried out with 49 obese adolescents and 47 non-obese adolescents as a control group...
May 23, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29789002/the-impact-of-economic-and-social-factors-on-the-prevalence-of-hepatitis-b-in-turkey
#20
Selma Tosun, Olgu Aygün, Hülya Özkan Özdemir, Elif Korkmaz, Durmuş Özdemir
BACKGROUND: Viral Hepatitis is one of the major global health problems, affecting millions of people every year. Limited information is available on the impact of social and economic factors on the prevalence of Hepatitis B virus (HBV) in Turkey. This study, contrary to other studies in the literature, was undertaken with the aim of examining the Majority of the excluded data come from the volunteers. METHODS: There are medical and the social-economic factors affecting the prevalence of HBV...
May 22, 2018: BMC Public Health
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