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https://www.readbyqxmd.com/read/28346272/influenza-in-children
#1
Janienne Kondrich, Michele Rosenthal
PURPOSE OF REVIEW: We review the current information and evidence available on the global burden of disease in the pediatric population, clinical presentation and complications, testing, treatment, and immunization. RECENT FINDINGS: In addition to multiple other risk factors for influenza complications, children with neurologic and neuromuscular disorders are significantly higher risk for serious complications. In practice, there is no lower age limit for children with influenza who can be treated with oseltamivir...
March 24, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28345736/-kleine-levin-syndrome-differential-diagnosis-in-recurrent-encephalitic-syndromes-in-adolescence
#2
A Duat-Rodriguez, I Martinez-Albadalejo, I Perez-Sebastian, V Cantarin-Extremera, A Hedrera-Fernandez, J J Garcia-Penas
INTRODUCTION: The Kleine-Levin syndrome is a rare disease of unknown origin characterized by recurrent and self-limited episodes of hypersomnia that are also accompanied by a cognitive and behavioral dysfunction. Patients present normal sleeping and behavior patterns between episodes. CASE REPORTS: We present three patients who are 14 years old: two boys and one girl. They started having the episodes after a predisposing factor (vaccine, influenza B and menstruation)...
April 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28344806/auditory-and-visual-hallucinations-after-influenza-vaccine-a-case-report
#3
Stefania Antoniazzi, Carla Carnovale, Aurelio Sessa, Marta Gentili, Marco Matacena, Maurizia Punginelli, Emilio Clementi, Sonia Radice
No abstract text is available yet for this article.
February 2017: Therapeutic Advances in Vaccines
https://www.readbyqxmd.com/read/28344402/preparation-of-mucosal-nanoparticles-and-polymer-based-inactivated-vaccine-for-newcastle-disease-and-h9n2-ai-viruses
#4
Heba M El Naggar, Mohamed Sayed Madkour, Hussein Ali Hussein
AIM: To develop a mucosal inactivated vaccines for Newcastle disease (ND) and H9N2 viruses to protect against these viruses at sites of infections through mucosal immunity. MATERIALS AND METHODS: In this study, we prepared two new formulations for mucosal bivalent inactivated vaccine formulations for Newcastle and Avian Influenza (H9N2) based on the use of nanoparticles and polymer adjuvants. The prepared vaccines were delivered via intranasal and spray routes of administration in specific pathogen-free chickens...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28343904/clinical-and-serologic-responses-after-a-two-dose-series-of-high-dose-influenza-vaccine-in-plasma-cell-disorders-a-prospective-single-arm-trial
#5
Andrew R Branagan, Eamon Duffy, Randy A Albrecht, Dennis L Cooper, Stuart Seropian, Terri L Parker, Geliang Gan, Fangyong Li, Daniel Zelterman, Chandra Sekhar Boddupalli, Lin Zhang, Rakesh Verma, Thomas M Ferencz, Madhav V Dhodapkar
BACKGROUND: Patients with multiple myeloma (MM) and other plasma cell disorders are highly susceptible to influenza infections, which are major causes of morbidity in this population, despite the routine administration of a seasonal influenza vaccination. Existing data are limited by small and retrospective studies, which suggest poor seroprotection rates of < 20% after standard influenza vaccination in patients with MM. PATIENTS AND METHODS: Patients with plasma cell dyscrasia (n = 51) were treated with a 2-dose series of high-dose inactivated trivalent influenza vaccine during the 2014 to 2015 influenza season...
March 7, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28343782/lifestyle-socioeconomic-characteristics-and-medical-history-of-elderly-persons-who-receive-seasonal-influenza-vaccination-in-a-tax-supported-healthcare-system
#6
Maja Hellfritzsch, Reimar Wernich Thomsen, Lisbeth Munksgård Baggesen, Finn Breinholt Larsen, Henrik Toft Sørensen, Christian Fynbo Christiansen
BACKGROUND: Observational studies on effectiveness of influenza vaccination in the elderly are thought to be biased by healthier lifestyles and higher socioeconomic status among vaccinated vs. unvaccinated persons. We examined this hypothesis in a uniform tax-supported health care system with free-of-charge influenza vaccination to the elderly. METHODS: We conducted a cross-sectional study among Danes aged 65-79years participating in a survey. We compared elderly persons with and without a recent (within six months) influenza vaccination in terms of (i) lifestyle and socioeconomic characteristics obtained from the survey and (ii) health factors including medical history provided by Danish registries...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343777/neisseria-meningitidis-nasopharyngeal-carriage-during-the-hajj-a-cohort-study-evaluating-the-need-for-ciprofloxacin-prophylaxis
#7
Ziad A Memish, Jaffar A Al-Tawfiq, Malak Almasri, Esam I Azhar, Muhammad Yasir, Muneera S Al-Saeed, Huda Ben Helaby, Ray Borrow, Abdulhafeez Turkistani, Abdallah Assiri
BACKGROUND: The annual Muslim pilgrimage has the potential of increase risk for acquisition of Neisseria meningitidis. Here, we evaluate the Hajj impact on the prevalence of N. meningitidis carriage in a paired and non-paired cohort of pilgrims. Secondary objectives were to calculate the compliance with recommended vaccination. METHODS: This is a prospective paired (arriving and departing), non-paired arriving and non-paired departing cohort study with the collection of nasopharyngeal samples at the start and the end of the Hajj...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343775/lower-vaccine-uptake-amongst-older-individuals-living-alone-a-systematic-review-and-meta-analysis-of-social-determinants-of-vaccine-uptake
#8
REVIEW
Anu Jain, A J van Hoek, Delia Boccia, Sara L Thomas
INTRODUCTION: Vaccination is a key intervention to reduce infectious disease mortality and morbidity amongst older individuals. Identifying social factors for vaccine uptake enables targeted interventions to reduce health inequalities. OBJECTIVE: To systematically appraise and quantify social factors associated with vaccine uptake amongst individuals aged ≥60years from Europe. METHODS: We searched Medline and Embase from inception to 24/02/2016...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343772/report-of-the-who-technical-consultation-on-the-effect-of-maternal-influenza-and-influenza-vaccination-on-the-developing-fetus-montreal-canada-september-30-october-1-2015
#9
Deshayne B Fell, Zulfiqar A Bhutta, Jennifer A Hutcheon, Ruth A Karron, Marian Knight, Michael S Kramer, Arnold S Monto, Geeta K Swamy, Justin R Ortiz, David A Savitz
In 2012, the World Health Organization (WHO) released a position paper on influenza vaccination recommending that pregnant women have the highest priority for seasonal vaccination in countries where the initiation or expansion of influenza immunization programs is under consideration. Although the primary goal of the WHO recommendation is to prevent influenza illness in pregnant women, the potential benefits of maternal immunization in protecting young infants are also recognized. The extent to which maternal influenza vaccination may prevent adverse birth outcomes such as preterm birth or small-for-gestational-age birth, however, is unclear as available studies are in disagreement...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28342711/epidemiological-profile-and-vaccination-coverage-in-splenectomy-patients-in-a-health-area-of-murcia-1993-2012
#10
Yolanda Molina-Salas, Francisco José Romera-Guirado, Jaime Jesús Pérez-Martín, María Nieves Peregrín-González, David Góngora-Soria
OBJECTIVE: Splenectomy patients have a high risk of suffering severe infections, many of them preventable by vaccination. The aim of the study was to analyse the clinical epidemiological characteristics and vaccine coverage of these patients in Health Area III of the Region of Murcia. METHOD: A cross-sectional study was conducted on a population of patients that were splenectomised during the period 1993-2012, according to the Register of the Basic Minimum Data Set...
March 22, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28342667/a-fast-and-efficient-purification-platform-for-cell-based-influenza-viruses-by-flow-through-chromatography
#11
Yu-Fen Tseng, Tsai-Chuan Weng, Chia-Chun Lai, Po-Ling Chen, Min-Shi Lee, Alan Yung-Chih Hu
Since newly emerging influenza viruses with pandemic potentials occurred in recent years, the demand for producing pandemic influenza vaccines for human use is high. For the development of a quick and efficient vaccine production, we proposed an efficient purification platform from the harvest to the purified bulk for the cell-based influenza vaccine production. This platform based on flow-through chromatography and filtration steps and the process only involves a few purification steps, including depth filtration, inactivation by formaldehyde, microfiltration, ultrafiltration, anion-exchange and ligand-core chromatography and sterile filtration...
March 22, 2017: Vaccine
https://www.readbyqxmd.com/read/28341114/measuring-maternal-tdap-and-influenza-vaccination-rates-comparison-of-two-population-based-methods
#12
Ruth Koepke, Stephanie L Schauer, Jeffrey P Davis
Pregnant women are routinely recommended to receive Tdap and influenza vaccines to prevent disease and complications among mothers and newborns. Monitoring population trends in maternal vaccination is important in order to evaluate the implementation of these recommendations and to identify pockets of need. We present two methods for measuring maternal vaccination among a state population and discuss the strengths and drawbacks of each method. First, we matched maternal information from records of Wisconsin births during 2013-2015 with maternal vaccination records in the Wisconsin Immunization Registry...
March 21, 2017: Vaccine
https://www.readbyqxmd.com/read/28340974/herpes-zoster-vaccine-coverage-in-older-adults-in-the-u-s-2007-2013
#13
Dongmu Zhang, Kelly Johnson, Chrisann Newransky, Camilo J Acosta
INTRODUCTION: This study aimed to assess the coverage of herpes zoster (HZ) vaccine among a large cohort of insured individuals aged ≥50 years from 2007 to 2013, and to determine the factors associated with being vaccinated for adults aged ≥60 years. METHODS: This was a retrospective, observational study using the MarketScan® database conducted in 2015. The study population was U.S. adults aged ≥60 years during 2007-2013 and 50-59 years during 2011-2013. The claims of each eligible subject were evaluated post-index date to assess HZ vaccine uptake...
January 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28340322/immunogenicity-and-safety-of-primary-and-booster-vaccination-with-2-investigational-formulations-of-diphtheria-tetanus-and-haemophilus-influenzae-type-b-antigens-in-a-hexavalent-dtpa-hbv-ipv-hib-combination-vaccine-in-comparison-with-the-licensed-infanrix-hexa
#14
Timo Vesikari, Luis Rivera, Tiina Korhonen, Anitta Ahonen, Brigitte Cheuvart, Marjan Hezareh, Winnie Janssens, Narcisa Mesaros
Safety and immunogenicity of 2 investigational formulations of diphtheria, tetanus and Haemophilus influenzae type b antigens of the combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliomyelitis-Hib vaccine (DTPa-HBV-IPV/Hib) were evaluated in a Primary (NCT01248884) and a Booster vaccination (NCT01453998) study. In the Primary study, 721 healthy infants (randomized 1:1:1) received 3 doses of DTPa-HBV-IPV/Hib formulation A (DATAPa-HBV-IPV/Hib), or B (DBTBPa-HBV-IPV/Hib) or the licensed DTPa-HBV-IPV/Hib vaccine (Infanrix hexa, GSK; control group) at 2, 3, 4 months of age...
March 24, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28340310/viruses-in-cystic-fibrosis-patients-airways
#15
Lisa Billard, Rozenn Le Berre, Léa Pilorgé, Christopher Payan, Geneviève Héry-Arnaud, Sophie Vallet
Although bacteria have historically been considered to play a major role in cystic fibrosis (CF) airway damage, a strong impact of respiratory viral infections (RVI) is also now recognized. Emerging evidence confirms that respiratory viruses are associated with deterioration of pulmonary function and exacerbation and facilitation of bacterial colonization in CF patients. The aim of this review is to provide an overview of the current knowledge on respiratory viruses in CF airways, to discuss the resulting inflammation and RVI response, to determine how to detect the viruses, and to assess their clinical consequences, prevalence, and interactions with bacteria...
March 24, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28337863/zoonotic-influenza-viruses-antigenic-and-genetic-characteristics-and-development-of-candidate-vaccine-viruses-for-pandemic-preparedness
#16
(no author information available yet)
No abstract text is available yet for this article.
March 24, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/28337690/using-active-choice-within-the-electronic-health-record-to-increase-influenza-vaccination-rates
#17
Mitesh S Patel, Kevin G Volpp, Dylan S Small, Craig Wynne, Jingsan Zhu, Lin Yang, Steven Honeywell, Susan C Day
BACKGROUND: Despite the benefits of influenza vaccination, each year more than half of adults in the United States do not receive it. OBJECTIVE: To evaluate the association between an active choice intervention in the electronic health record (EHR) and changes in influenza vaccination rates. DESIGN: Observational study. PATIENTS: Adults eligible for influenza vaccination with a clinic visit at one of three internal medicine practices at the University of Pennsylvania Health System between September 2010 and March 2013...
March 23, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28337492/flock-based-surveillance-for-low-pathogenic-avian-influenza-virus-in-commercial-breeders-and-layers-southwest-nigeria
#18
Daniel Oladimeji Oluwayelu, Ayoyimika Omolanwa, Adebowale Idris Adebiyi, Oluladun Comfort Aiki-Raji
BACKGROUND: Flock surveillance systems for avian influenza (AI) virus play a critical role in countries where vaccination is not practiced so as to establish the epidemiological characteristics of AI needed for the development of prevention and control strategies in such countries. MATERIALS AND METHODS: As part of routine AI monitoring in southwest Nigeria, a competitive ELISA was used for detecting influenza A virus antibodies in the sera of 461 commercial breeder and layer birds obtained from different flocks in Oyo State, Nigeria while haemagglutination inhibiting antibodies against low pathogenic AI viruses (LPAIVs) were detected using H5N2, H7N7 and H9N2 subtype-specific antigens...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28337196/salmonella-typhi-porins-ompc-and-ompf-are-potent-adjuvants-for-t-dependent-and-t-independent-antigens
#19
Marisol Pérez-Toledo, Nuriban Valero-Pacheco, Rodolfo Pastelin-Palacios, Cristina Gil-Cruz, Christian Perez-Shibayama, Mario A Moreno-Eutimio, Ingeborg Becker, Sonia Mayra Pérez-Tapia, Lourdes Arriaga-Pizano, Adam F Cunningham, Armando Isibasi, Laura C Bonifaz, Constantino López-Macías
Several microbial components, such as bacterial DNA and flagellin, have been used as experimental vaccine adjuvants because of their inherent capacity to efficiently activate innate immune responses. Likewise, our previous work has shown that the major Salmonella Typhi (S. Typhi) outer membrane proteins OmpC and OmpF (porins) are highly immunogenic protective antigens that efficiently stimulate innate and adaptive immune responses in the absence of exogenous adjuvants. Moreover, S. Typhi porins induce the expression of costimulatory molecules on antigen-presenting cells through toll-like receptor canonical signaling pathways...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28335511/1st-workshop-of-the-canadian-society-for-virology
#20
Craig McCormick, Nathalie Grandvaux
The 1st Workshop of the Canadian Society for Virology (CSV2016) was a Special Workshop of the 35th Annual Meeting for the American Society for Virology, held on 18 June 2016 on the beautiful Virginia Tech campus in Blacksburg, Virginia. The workshop provided a forum for discussion of recent advances in the field, in an informal setting conducive to interaction with colleagues. CSV2016 featured two internationally-renowned Canadian keynote speakers who discussed translational virology research; American Society for Virology President Grant McFadden (then from University of Florida, now relocated to Arizona State University) who presented his studies of oncolytic poxviruses, while Matthew Miller (McMaster University) reviewed the prospects for a universal influenza vaccine...
March 20, 2017: Viruses
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