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https://www.readbyqxmd.com/read/28322446/increased-long-term-risk-of-hearing-loss-in-patients-with-traumatic-brain-injury-a-nationwide-population-based-study
#1
Wei-Chuan Shangkuan, Hung-Che Lin, Cheng-Ping Shih, Chun-An Cheng, Hueng-Chuen Fan, Chi-Hsiang Chung, Fu-Huang Lin, Chang-Huei Tsao, Wu-Chien Chien
OBJECTIVES/HYPOTHESIS: We investigated incidences of hearing loss among patients with traumatic brain injury (TBI) to evaluate whether they had a higher risk of hearing loss than the general population. STUDY DESIGN: Cohort study. METHODS: Inpatient data from the Taiwan National Health Insurance Research Database from January 1, 2000 to December 31, 2010 were recorded. Patients with TBI and a retrospective comparison cohort were analyzed. Each subject was individually traced from their index date to identify subjects who subsequently received a diagnosis of hearing loss...
March 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28322095/therapeutic-inertia-and-intensified-treatment-in-diabetes-mellitus-prescription-patterns-a-nationwide-population-based-study-in-taiwan
#2
Li-Ying Huang, Hseng-Long Yeh, Ming-Chin Yang, Wen-Yi Shau, Syi Su, Mei-Shu Lai
Objective To measure therapeutic inertia by characterizing prescription patterns using secondary data obtained from the nationwide diabetes mellitus pay-for-performance (DM-P4P) programme in Taiwan. Methods Using reimbursement claims from Taiwan's National Health Insurance Research Database, a nationwide retrospective cohort study was undertaken of patients with diabetes mellitus who participated in the DM-P4P programme from 2006-2008. Glycosylated haemoglobin results were used to evaluate modifications in therapy in response to poor diabetes control...
December 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/28319162/risk-of-acute-myocardial-infarction-in-patients-with-gastroesophageal-reflux-disease-a-nationwide-population-based-study
#3
Wei-Yi Lei, Jen-Hung Wang, Shu-Hui Wen, Chih-Hsun Yi, Jui-Sheng Hung, Tso-Tsai Liu, William C Orr, Chien-Lin Chen
OBJECTIVE: Gastroesophageal reflux disease (GERD) is a common disease which can cause troublesome symptoms and affect quality of life. In addition to esophageal complications, GERD may also be a risk factor for extra-esophageal complications. Both GERD and coronary artery disease (CAD) can cause chest pain and frequently co-exist. However, the association between GERD and acute myocardial infarction (AMI) remain unclear. The purpose of the study was to compare the incidence of acute myocardial infarction in GERD patients with an age-, gender-, and comorbidity matched population free of GERD...
2017: PloS One
https://www.readbyqxmd.com/read/28316630/patients-with-epididymo-orchitis-and-meteorological-impact-in-taiwan-a-nationwide-population-based-study
#4
Jui-Ming Liu, Ying-Hsu Chang, Te-Wei Ho, Fung-Wei Chang, See-Tong Pang, Ren-Jun Hsu, Po-Hung Lin
Background. Epididymo-orchitis is a common infectious disease among men, especially men aged 20 to 39 years. The aim of this study was to analyze possible associations of various meteorological indicators on the incidence of epididymo-orchitis in Taiwan. Methods and Materials. This nationwide population-based study collected data on cases of epididymo-orchitis that were newly diagnosed from 2001 to 2013 in Taiwan. Monthly meteorological indicators, including average temperatures, humidity, rainfall, total rain days, and sunshine hours, were collected from the Central Weather Bureau of Taiwan...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28306623/risk-of-epilepsy-in-individuals-with-posttraumatic-stress-disorder-a-nationwide-longitudinal-study
#5
Yu-Hsiung Chen, Han-Ting Wei, Ya-Mei Bai, Ju-Wei Hsu, Kai-Lin Huang, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Yi-Hui Wu, Tai-Long Pan, Tzeng-Ji Chen, Shih-Jen Tsai, Mu-Hong Chen
OBJECTIVE: Several cross-sectional studies reported a relationship between post-traumatic stress disorder (PTSD) and epilepsy. However, the temporal association between PTSD and epilepsy has rarely been investigated. We hypothesized that the risk of developing epilepsy later in life would be higher in patients with PTSD than in those without PTSD. METHODS: Using the Taiwan National Health Insurance Research Database, 6425 individuals with PTSD and 24,980 age-/sex-matched controls were enrolled between 2002 and 2009 in our study, and followed up to the end of 2011...
March 17, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28301517/association-of-lower-urinary-tract-syndrome-with-peripheral-arterial-occlusive-disease
#6
Wei-Yu Lin, Karl-Erik Andersson, Cheng-Li Lin, Chia-Hung Kao, Hsi-Chin Wu
PURPOSE: To describe atherosclerosis may lead to chronic bladder ischemia, eventually resulting in lower urinary tract syndrome (LUTS), and peripheral arterial occlusive disease (PAOD). We investigated the association of LUTS with PAOD. METHODS: This nationwide population-based cohort study was based on data from the Taiwan National Health Insurance Database from 2000 to 2010; follow-up lasted until the end of 2011. We identified patients with newly diagnosed LUTS by using International Classification of Diseases, Ninth Revision, Clinical Modification codes...
2017: PloS One
https://www.readbyqxmd.com/read/28301063/use-of-simvastatin-and-risk-of-acute-pancreatitis-a-nationwide-case-control-study-in-taiwan
#7
Chih-Ming Lin, Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai
The correlation between simvastatin use and acute pancreatitis is explored. A case-control study was conducted to analyze claim data from the Taiwan National Health Insurance Program. The case group comprising a total of 3882 subjects aged 20 to 84 years with their first acute pancreatitis episode occurring between 1998 and 2011 formed the case group, against 3790 randomly selected controls matched for sex, age, comorbidities, and index year of acute pancreatitis diagnosis. Recent use of simvastatin was defined as subjects whose last remaining simvastatin tablet was noted ≤7 days before the date of acute pancreatitis diagnosis...
March 16, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28300435/long-term-outcomes-of-lercanidipine-versus-other-calcium-channel-blockers-in-newly-diagnosed-hypertension-a-nationwide-cohort-study
#8
Kai-Hung Cheng, Kai-Chun Cheng, Kai-Yuan Cheng, Yi-Hsin Yang, Chung-Wei Lee, Wen-Ter Lai
OBJECTIVE: Calcium channel blockers (CCBs) have been proved to have beneficial effects on cardiovascular (CV) outcomes, especially in stroke. Lercanidipine, a highly lipophilic CCB, lacks data regarding long-term outcomes including: CV, stroke, renal and all-cause mortality which are aimed to be clarified in this retrospective cohort study. PATIENTS AND METHODS: A total of 144630 newly diagnosed hypertension (HTN) (age: 18 - 65 y/o) patients in 2005 from the Taiwan's National Health Insurance Research Database were enrolled in this observational study...
March 16, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28298371/temporal-trends-in-treatment-and-outcomes-of-acute-myocardial-infarction-in-patients-with-chronic-obstructive-pulmonary-disease-a-nationwide-population-based-observational-study
#9
Tse-Hsuan Su, Shang-Hung Chang, Pei-Chun Chen, Yi-Ling Chan
BACKGROUND: Acute myocardial infarction is a major cause of hospitalization and death in patients with chronic obstructive pulmonary disease (COPD); however, temporal trends in the management and clinical outcomes of these patients remain unclear. METHODS AND RESULTS: We conducted an observational study by using a representative sample of 1 million beneficiaries from the Taiwan National Health Insurance Research Database. Comorbidities, in-hospital treatment, and outcomes were compared for patients with acute myocardial infarction with and without COPD between 2004 and 2013...
March 15, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28297597/leptospirosis-and-depression-a-nationwide-cohort-analysis
#10
Chun-Hsiang Chiu, Ying-Chuan Wang, Cheng-Li Lin, Feng-You Lee, Chia-Hung Kao
OBJECTIVE: We conducted a retrospective cohort study to investigate whether leptospirosis is a risk factor for depression. METHOD: From the Taiwan National Health Insurance Research Database between 2000 and 2010, patients with leptospirosis (ICD-9 code 100) who did not have a history of depression (ICD-9-CM codes 296.2, 296.3, 300.4, and 311) before the index date were enrolled (leptospirosis cohort). For each patient with leptospirosis, 1 control without a history of leptospirosis and depression was randomly selected (nonleptospirosis cohort)...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28296941/the-association-between-methylphenidate-treatment-and-the-risk-for-fracture-among-young-adhd-patients-a-nationwide-population-based-study-in-taiwan
#11
Vincent Chin-Hung Chen, Yao-Hsu Yang, Yin-To Liao, Ting-Yu Kuo, Hsin-Yi Liang, Kuo-You Huang, Yin-Cheng Huang, Yena Lee, Roger S McIntyre, Tzu-Chin Lin
Attention-deficit hyperactivity disorder (ADHD) is associated with higher risk for fracture. Whether the medical treatment for ADHD would mitigate the risk remains unclear. In this study, we sought to investigate the effect of methylphenidate treatment on risk for fracture, as well the moderational role of treatment duration on the risk of fracture, in a large national sample. Cases less than 18 years old were identified from Taiwan's National Health Insurance Research Database with a new primary diagnosis of ADHD (ICD-9:314) between 1996 and 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28296786/association-between-macular-degeneration-and-mild-to-moderate-chronic-kidney-disease-a-nationwide-population-based-study
#12
Chun-Yu Chen, Ciou-Sia Dai, Chin-Chan Lee, Yu-Chiau Shyu, Ting-Shuo Huang, Ling Yeung, Chi-Chin Sun, Huang-Yu Yang, I-Wen Wu
Chronic kidney disease (CKD) and macular degeneration (MD) are 2 grave diseases leading to significant disability secondary to renal failure and blindness. The 2 diseases share not only common risk factors but also similar pathogenic mechanisms to renal and retinal injuries. Previous epidemiological studies indicated association between these 2 diseases. However, this concept is challenged by recent investigations. Patients with mild to moderate CKD (n = 30,696) between January 1, 1995 and December 31, 2005 were selected from the Taiwan National Health Insurance Database...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28296028/impact-of-hospital-volume-on-long-term-neurological-outcome-in-patients-undergoing-carotid-artery-stenting
#13
Chi-Sheng Hung, Chih-Fan Yeh, Mao-Shin Lin, Ying-Hsien Chen, Ching-Chang Huang, Hung-Yuan Li, Hsien-Li Kao
BACKGROUND: The impact of hospital volume on long-term outcome after carotid artery stenting (CAS) remains unknown. OBJECTIVES: We designed a nationwide cohort study to elucidate the impact of hospital volume on the incidence of stroke after CAS. METHODS: The Taiwan National Health Insurance Research database was used to identify all patients admitted for CAS from 2008 to 2012. We defined high-volume hospitals as those performing more than 20 CAS per year...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28295637/malignant-transformation-of-oral-submucous-fibrosis-in-taiwan-a-nationwide-population-based-retrospective-cohort-study
#14
Po-Yu Yang, Yi-Tzu Chen, Yu-Hsun Wang, Ni-Yu Su, Hui-Chieh Yu, Yu-Chao Chang
BACKGROUND: Oral submucous fibrosis (OSF) is a one of the well-recognized oral potentially malignant disorders. In this study, we investigated the malignant transformation of OSF in a Taiwanese population. METHODS: A retrospective cohort study was analyzed from Taiwan's National Health Insurance Research Database. A comparison cohort that was randomly frequency-matched with the OSF cohort according to age, sex, and index year. Oral leukoplakia (OL) was further stratified to evaluate for the possible synergistic effects for OSF-associated malignant transformation...
March 14, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28288600/complementary-traditional-chinese-medicine-use-in-children-with-cerebral-palsy-a-nationwide-retrospective-cohort-study-in-taiwan
#15
Hou-Hsun Liao, Hung-Rong Yen, Chih-Hsin Muo, Yu-Chen Lee, Mei-Yao Wu, Li-Wei Chou, Mao-Feng Sun, Tung-Ti Chang
BACKGROUND: Complementary traditional Chinese medicine (TCM) has been used to treat patients with cerebral palsy (CP). However, large-scale surveys examining its use in the treatment of CP and associated disorders are lacking. METHODS: We enrolled 11,218 patients ≤ 18 years of age with CP in the Taiwanese National Health Insurance Research Database from 1995 to 2011. Patients were categorized as TCM users (n = 6,997; 62.37%) and non-TCM users (n = 4,221; 37...
March 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28286341/rapid-adiposity-growth-increases-risks-of-new-onset-asthma-and-airway-inflammation-in-children
#16
Y-C Chen, A-H Chih, J-R Chen, T-H Liou, W-H Pan, Y L Lee
BACKGROUND/OBJECTIVES: We aim to (1) examine the influence of long-term adiposity status/ short-term adiposity changes on asthma with high or low fractional exhaled nitric oxide (FeNO), and (2) to determine the differences in long-term adiposity status/ short-term adiposity changes on atopy, airway inflammation, and pulmonary function. SUBJECTS/METHODS: We recruited 2450 fourth-to-sixth-grade children from the nationwide Taiwan Children Health Study. Data regarding various adiposity indicators, atopic status, pulmonary function tests, and asthma outcomes were collected annually...
March 13, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28280346/trend-characteristics-and-pharmacotherapy-of-adults-diagnosed-with-attention-deficit-hyperactivity-disorder-a-nationwide-survey-in-taiwan
#17
Yu-Shian Cheng, Yu-Chiau Shyu, Sheng-Yu Lee, Shin-Sheng Yuan, Chun-Ju Yang, Kang-Chung Yang, Tung-Liang Lee, Liang-Jen Wang
OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) in adults may result in functional impairment warranting clinical interventions. However, few studies have investigated the diagnosis and treatment rates of adult ADHD in non-Caucasian ethnic groups. This study used nationwide population-based data to investigate the rate of diagnosis, associated characteristics, and pharmacological treatment for adult ADHD in Taiwan. METHODS: Adults (age ≥18 years) newly diagnosed with ADHD (n=5,397) between January 2000 and December 2011 were enrolled from the National Health Insurance database in Taiwan...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28279996/incidence-and-relative-risk-for-developing-cancer-among-patients-with-copd-a-nationwide-cohort-study-in-taiwan
#18
Chung-Han Ho, Yi-Chen Chen, Jhi-Joung Wang, Kuang-Ming Liao
OBJECTIVES: This observational study aimed to examine the incidence of malignant diseases, including specific cancer types, after the diagnosis of chronic obstructive pulmonary disease (COPD) in Taiwanese patients. SETTING: Taiwan's National Health Insurance Research Database. PARTICIPANTS: The definition of a patient with COPD was a patient with a discharge diagnosis of COPD or at least 3 ambulatory visits for COPD. The index date was the date of the first COPD diagnosis...
March 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28277863/increased-subsequent-risk-of-inflammatory-bowel-disease-association-in-patients-with-chronic-pancreatitis-with-a-nationwide-population-based-cohort-study
#19
Yu-Long Chen, Chin-Wang Hsu, Cheng-Chung Cheng, Giou-Teng Yiang, Chin-Sheng Lin, Cheng-Li Lin, Fung-Chang Sung, Ji-An Liang
PURPOSE: To investigate the relationship between chronic pancreatitis (CP) and inflammatory bowel disease (IBD) in a large population-based cohort study. METHODS: Data were obtained from the Taiwan National Health Insurance Research Database. The cohort study comprised 17 796 patients newly diagnosed with CP between 2000 and 2010 and 71 164 matched controls. A Cox proportional hazards model was used for evaluating the risk of IBD in the CP and comparison cohorts...
February 25, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28272783/variations-of-stereotypies-in-individuals-with-rett-syndrome-a-nationwide-cross-sectional-study-in-taiwan
#20
Lee Chin Wong, Pi-Lien Hung, Tz-Yun Jan, Wang-Tso Lee
Individuals with Rett syndrome (RTT) can have variable manifestations of stereotypies. In this nation-wide cross-sectional study, we recruited all individuals with RTT in Taiwan diagnosed as RTT by neurologists based on genetic findings and diagnostic criteria. The data were collected using questionnaire. A total 43 cases of typical RTT and 15 cases of atypical RTT, aged from 2.1 to 40.1 years, were enrolled. They included 3 (5.2%) in stage II, 42 (72.4%) in stage III, and 13 (22.4%) in stage IV. All individuals presented with at least one stereotypy...
March 8, 2017: Autism Research: Official Journal of the International Society for Autism Research
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