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https://www.readbyqxmd.com/read/28939060/familial-aggregation-of-nasopharyngeal-carcinoma-in-taiwan
#1
Shiang-Fu Huang, Jen-Hao Hsiao, Chi-Kuan Young, Hui-Tzu Chien, Chang-Fu Kuo, Lai-Chu See, Shue-Fen Luo, Lu-Hsiang Huang, Chun-Ta Liao, Tung-Chieh Joseph Chang
BACKGROUND: The incidence of nasopharyngeal carcinoma (NPC) is higher in Chinese than in Caucasian populations. Genetic, viral, and lifestyle factors may explain these ethnic differences in the incidence of NPC. In the present study, we examined the familial aggregation, heritability, and relative risks (RRs) of NPC using a nationwide database in Taiwan. METHODS: A population-based family study was conducted using the Taiwan National Health Insurance Research Database...
October 2017: Oral Oncology
https://www.readbyqxmd.com/read/28934668/diabetes-mellitus-increased-all-cause-mortality-rate-among-newly-diagnosed-tuberculosis-patients-in-an-asian-population-a-nationwide-population-based-study
#2
Po-Yen Ko, Shi-Dou Lin, Ming-Chia Hsieh, Yu-Cheng Chen
AIMS: To investigate the effect of diabetes mellitus (DM) on all-cause mortality among patients with newly-diagnosed tuberculosis (TB) in an Asian population. We also identified risk factors for mortality in these patients. METHODS: The data were obtained from the National Health Insurance Research Database and included 9831 newly-diagnosed TB individuals and 1627 TB mortality cases in the period of 2000-2010. The mortality data were divided into a DM group and a non-DM group...
September 1, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28931170/strengthening-teachers-abilities-to-implement-a-vision-health-program-in-taiwanese-schools
#3
L C Chang, L L Liao, M I Chen, Y Z Niu, P L Hsieh
We designed a school-based, nationwide program called the 'New Era in Eye Health' to strengthen teacher training and to examine whether the existence of a government vision care policy influenced teachers' vision care knowledge and students' behavior. Baseline data and 3-month follow-up data were compared. A random sample of teachers (n = 660) from school vision health clusters in 22 cities/counties in Taiwan were invited to participate in our study and 436 agreed to participate (response rate = 66.1%). The mean age of participant teachers was 41...
October 1, 2017: Health Education Research
https://www.readbyqxmd.com/read/28928665/nationwide-case-control-study-examining-the-association-between-tamoxifen-use-and-alzheimer-s-disease-in-aged-women-with-breast-cancer-in-taiwan
#4
Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai
Background and Objectives: Little is known about the association between tamoxifen use and Alzheimer's disease in women with breast cancer. The study aimed to explore the association between tamoxifen use and Alzheimer's disease in aged women with breast cancer in Taiwan. Methods: We conducted a retrospective nationwide case-control study using the database of the Taiwan National Health Insurance Program. Totally, 173 female subjects with breast cancer aged ≥ 65 years with newly diagnosed Alzheimer's disease from 2000 to 2011 were identified as the cases...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28926165/pre-stroke-physical-activity-is-associated-with-fewer-post-stroke-complications-lower-mortality-and-a-better-long-term-outcome
#5
Chi-Pang Wen, Chung-Hsiang Liu, Jiann-Shing Jeng, Shih-Pin Hsu, Chih-Hung Chen, Li-Ming Lien, An-Chih Chen, Jiunn-Tay Lee, Ping-Kun Chen, Chih-Shan Hsu, Chang-Ming Chern, Chien-Chung Chen, Ming-Chin Hsu, Kang Lu, Han-Jung Chen, Hao-Kuang Wang, Chih-Hsin Muo, Chung Y Hsu
BACKGROUND AND PURPOSE: Physical activity is associated with a reduced incidence of first-time stroke; however, few studies have examined the effect of pre-stroke physical activity on post-stroke complications and clinical outcomes. METHODS: A total of 39,835 cases of stroke registered in the nationwide stroke registry system of Taiwan between 2006 and 2009 were analyzed according to 5 levels of severity as determined by NIHSS (National Institutes of Health Stroke Scale) score upon hospital admission...
September 19, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28916233/risk-of-pneumonia-in-patients-with-insomnia-a-nationwide-population-based-retrospective-cohort-study
#6
Chia-Ling Lin, Ta-Chun Liu, Chi-Hsiang Chung, Wu-Chien Chien
Evidence is lacking regarding whether insomnia increases the risk of infectious disease. Accordingly, the present study examined the risk of pneumonia in patients with insomnia. This study was a population-based retrospective cohort study on a cohort of 8061 patients with insomnia and a control cohort of 16,112 patients (matched by age, sex, and year of diagnosis) from the Taiwan National Health Insurance Research Database for the 2000-2010 period. Overall incidence of pneumonia was 50.6 per 1000 person-years in the insomnia cohort, which was significantly higher than that in the control cohort (30...
September 12, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28915698/risk-of-aortic-aneurysm-and-dissection-in-patients-with-autosomal-dominant-polycystic-kidney-disease-a-nationwide-population-based-cohort-study
#7
Pei-Hsun Sung, Yao-Hsu Yang, Hsin-Ju Chiang, John Y Chiang, Chi-Jen Chen, Chien-Ting Liu, Cheuk-Man Yu, Hon-Kan Yip
Although cardiovascular complications are the most common cause of death in patients with autosomal-dominant polycystic kidney disease (ADPKD), the incidence and risk of aortic aneurysm and dissection (AAD) in ADPKD remains unclear due to limited data and insufficient cases. We utilized the data from Taiwan National Health Insurance Research Database (NHIRD) to do a population-based cohort study (1997-2008). After excluding those patients with age <18 years old and initially concomitant diagnoses of end-stage renal disease and AAD, a total of 2076 ADPKD patients were selected from 1,000,000 of general population...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28906354/the-influence-of-renal-dialysis-and-hip-fracture-sites-on-the-10-year-mortality-of-elderly-hip-fracture-patients-a-nationwide-population-based-observational-study
#8
Li-Wei Hung, Yi-Ting Hwang, Guey-Shiun Huang, Cheng-Chih Liang, Jinn Lin
Hip fractures in older people requiring dialysis are associated with high mortality. Our study primarily aimed to evaluate the specific burden of dialysis on the mortality rate following hip fracture. The secondary aim was to clarify the effect of the fracture site on mortality. A retrospective cohort study was conducted using Taiwan's National Health Insurance Research Database to analyze nationwide health data regarding dialysis and non-dialysis patients ≥65 years who sustained a first fragility-related hip fracture during the period from 2001 to 2005...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28899350/epidemiological-profile-and-obstetric-outcomes-of-patients-with-peripartum-congestive-heart-failure-in-taiwan-a-retrospective-nationwide-study
#9
Ying-Jen Chang, Chung-Han Ho, Jen-Yin Chen, Ming-Ping Wu, Chia-Hung Yu, Jhi-Joung Wang, Chia-Ming Chen, Chin-Chen Chu
BACKGROUND: During pregnancy, the hyperdynamic physiology of circulation can exacerbate many cardiovascular disorders. Congestive heart failure (CHF) usually occurs during late pregnancy, which is significantly associated with a high level of maternal and neonatal morbidities and mortalities. The profile of women who develop peripartum CHF (PCHF) is unknown. We investigated the epidemiological profiles of PCHF. METHODS: In this retrospective cohort study, PCHF patients were identified using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes in Taiwan's National Health Insurance Research Database...
September 12, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28898259/association-between-retinal-vein-occlusion-and-an-increased-risk-of-acute-myocardial-infarction-a-nationwide-population-based-follow-up-study
#10
Yu-Yen Chen, Shwu-Jiuan Sheu, Hsiao-Yun Hu, Dachen Chu, Pesus Chou
OBJECTIVE: To investigate a possible association between retinal vein occlusion (RVO) and an increased risk of developing acute myocardial infarction (AMI). DESIGN: A population-based retrospective cohort study using the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 1st January, 2001 to 31st December, 2013. METHODS: A total of 37921 subjects with RVO were enrolled in the RVO group, and 113763 subjects without RVO were enrolled in the comparison group...
2017: PloS One
https://www.readbyqxmd.com/read/28895425/predictors-of-subsequent-myocardial-infarction-stroke-and-death-in-stable-post-myocardial-infarction-patients-a-nationwide-cohort-study
#11
Dong-Yi Chen, Chen-Yu Li, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh, Tien-Hsing Chen, Shao-Wei Chen, Chao-Yung Wang, Shang-Hung Chang, Cheng-Hung Lee, Ming-Lung Tsai, Ming-Yun Ho, Jih-Kai Yeh, Chee-Jen Chang, Ming-Shien Wen
BACKGROUND: This study investigated the predictors of subsequent cardiovascular events in stable post-myocardial infarction patients in Taiwan. METHODS: A total of 11,183 patients were recruited who had survived one year post-myocardial infarction without subsequent events of recurrent myocardial infarction or stroke from the Taiwan National Health Insurance Research Database. Their composite cardiovascular event rates were identified. RESULTS: The composite cardiovascular events rate in three year follow-up in the post-myocardial infarction population was 13...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28894360/the-evaluation-of-%C3%AE-adrenoceptor-blocking-agents-in-patients-with-copd-and-congestive-heart-failure-a-nationwide-study
#12
Kuang-Ming Liao, Tien-Yu Lin, Yaw-Bin Huang, Chen-Chun Kuo, Chung-Yu Chen
OBJECTIVE: β-Blockers are safe and improve survival in patients with both congestive heart failure (CHF) and COPD. However, the superiority of different types of β-blockers is still unclear among patients with CHF and COPD. The association between β-blockers and CHF exacerbation as well as COPD exacerbation remains unclear. The objective of this study was to compare the outcome of different β-blockers in patients with concurrent CHF and COPD. PATIENTS AND METHODS: We used the National Health Insurance Research Database in Taiwan to conduct a retrospective cohort study...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28892712/relationship-between-serum-total-bilirubin-levels-and-mortality-in-uremia-patients-undergoing-long-term-hemodialysis-a-nationwide-cohort-study
#13
Hui-Hsien Su, Chia-Man Kao, Yi-Chun Lin, Yen-Chung Lin, Chih-Chin Kao, Hsi-Hsien Chen, Chih-Cheng Hsu, Kuan-Chou Chen, Chiung-Chi Peng, Mai-Szu Wu
BACKGROUND AND AIMS: Previous studies show that serum bilirubin has potent antioxidant effect and is associated with protection from kidney damage and reduce cardiovascular events. The aim of this study was to examine the association of serum total bilirubin level and mortality in uremia patients who underwent hemodialysis. METHODS: This is a nationwide retrospective long-term cohort study. Patients were registered in the Taiwan Renal Registry Data System (TWRDS) from 2005 to 2012...
September 4, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28890525/cognitive-development-after-kawasaki-disease%C3%A3-clinical-study-and-validation-using-a-nationwide-population-based-cohort
#14
Liang-Jen Wang, Ho-Chang Kuo
BACKGROUND: This purpose of this study was to investigate whether Kawasaki disease (KD) increases the risk of cognitive impairment. In this clinical study, cognitive profiles were compared between KD patients, control subjects, and a nationwide population-based cohort to determine the potential correlation between KD and a subsequent diagnosis of an intellectual disability.Methods and Results:The clinical study consisted of 168 KD patients (mean age 5.6 years, 62.5% male) and 81 healthy controls (mean age 6...
September 9, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28890037/the-association-between-scabies-and-myasthenia-gravis-a-nationwide-population-based-cohort-study
#15
Ren-Jun Hsu, Chien-Yu Lin, Fung-Wei Chang, Chun-Fa Huang, Heng-Chang Chuang, Jui-Ming Liu
Scabies is an infectious inflammatory pruritic skin disease. Cytokine-mediated inflammatory processes contribute to the pathologic mechanism in scabies. Myasthenia gravis (MG) is also an autoimmune disease that is mediated by cytokines. The study aimed to investigate the association between scabies and myasthenia gravis. We conducted a nationwide population-based cohort study utilized data from the National Health Insurance Research Database (NHIRD) of Taiwan. Patients with scabies (n=5429) and control subjects without scabies (n=20,176) were enrolled...
September 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28884595/risk-of-osteoporosis-in-thyroid-cancer-patients-using-levothyroxine-a-population-based-study
#16
Shih-Yi Lin, Cheng-Li Lin, Hsien-Te Chen, Chia-Hung Kao
BACKGROUND: The outcomes of thyroid cancer patients using levothyroxine are largely undetermined. METHODS: The study population consisted of 9,398 patients newly diagnosed with thyroid cancer; their data was retrieved from a subset of the National Health Insurance Research Database of Taiwan during the period of 1999-2011. In this nationwide retrospective cohort study, we compared the risk of osteoporosis among thyroid cancer patients with levothyroxine use, those without levothyroxine use, and propensity score-matched nonthyroid controls...
September 8, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28881891/induction-therapy-before-surgery-improves-survival-in-patients-with-clinical-t3n0-esophageal-cancer-a-nationwide-study-in-taiwan
#17
Y-K Chao, H-Y Ku, C-Y Chen, T-W Liu
The utility of induction therapy (IT) in patients with resectable esophageal cancer remains controversial, especially when clinical evidence of nodal metastases is lacking. We sought to compare the survival impact of IT versus upfront surgery (US) in patients with cT3N0 esophageal cancer. We searched the Taiwan Cancer Registry for patients with cT3N0 esophageal cancer who underwent US or IT between 2008 and 2013. Multivariate Cox regression analysis was used to analyze the potential benefits of IT in terms of overall survival (OS) and disease-free survival (DFS)...
December 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28881762/erectile-dysfunction-and-the-risk-of-prostate-cancer
#18
Wei-Yu Lin, Ying-Hsu Chang, Cheng-Li Lin, Chia-Hung Kao, Hsi-Chin Wu
BACKGROUND: Prostate cancer (PCa) is the most commonly diagnosed malignancy and the third leading cause of cancer death among men in developed countries. Because some risk factors are common between erectile dysfunction (ED) and PCa, we investigated the association between ED and subsequent PCa. METHODS: This nationwide population-based cohort study used data from the Taiwan National Health Insurance Research Database for the period 2000-2010. We identified patients newly diagnosed with ED by using codes from the International Classification of Diseases, Ninth Revision, Clinical Modification...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28872268/risk-of-suicide-attempts-among-adolescents-and-young-adults-with-autism-spectrum-disorder-a-nationwide-longitudinal-follow-up-study
#19
Mu-Hong Chen, Tai-Long Pan, Wen-Hsuan Lan, Ju-Wei Hsu, Kai-Lin Huang, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Han-Ting Wei, Tzeng-Ji Chen, Ya-Mei Bai
BACKGROUND: Previous studies reported a high prevalence of depression among patients with autism spectrum disorder (ASD) and suggested a relationship between ASD and suicidality. However, whether ASD independently increases the risk of attempted suicide regardless of depression has not been determined. METHODS: Using the Taiwan National Health Insurance Research Database, 5,618 adolescents aged 12-17 years and young adults aged 18-29 years with ASD (ICD-9-CM code: 299) and 22,472 age- and sex-matched controls were enrolled between 2001 and 2009 and followed to the end of 2011...
August 29, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28871015/impact-of-chronic-obstructive-pulmonary-disease-on-patients-with-aortic-aneurysms-a-nationwide-retrospective-cohort-study-in-taiwan
#20
Kuang-Ming Liao, Chung-Yu Chen
OBJECTIVES: Aortic aneurysm (AA) is a leading cause of death worldwide. Chronic obstructive pulmonary disease (COPD) is a risk factor for AA, and the prognoses of COPD patients with AA who underwent/did not undergo an operation warrant investigation. DESIGN: A nationwide retrospective cohort study. SETTING: We included patients with AA older than 18 years who received their first AA diagnosis between 2005 and 2011 in Taiwan. PARTICIPANTS: This study enrolled 3263 COPD patients with AA before propensity score matching and 2127 COPD patients with AA after propensity score matching...
September 3, 2017: BMJ Open
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