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Carotid intima media thickness

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https://www.readbyqxmd.com/read/29156411/relationship-between-carotid-artery-sclerosis-and-blood-pressure-variability-in-essential-hypertension-patients
#1
Xianglin Chi, Min Li, Xia Zhan, Honghao Man, Shunliang Xu, Dingchang Zheng, Jianzhong Bi, Yingcui Wang, Chengyu Liu
OBJECTIVES: This study aimed to investigate the relationship between the presence of carotid arteriosclerosis (CAS) and blood pressure variability (BPV) in patients with essential hypertension. METHODS: One hundred and forty four essential hypertension patients underwent ambulatory BP monitoring for 24h after hospitalization. Common BPV metrics were calculated. General clinical parameters, including age, gender, height, weight, history of coronary heart disease, stroke, diabetes, hypertension, smoking and drink, were recorded...
March 18, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29153673/pregnancy-complications-and-later-vascular-ultrasound-measures-a-cohort-study
#2
Emily W Harville, Markus Juonala, Jorma S A Viikari, Mika Kähönen, Olli T Raitakari
OBJECTIVES: Pregnancy complications predict or even predispose to later cardiovascular disease in the mother. We examined whether pregnancy complications are associated with post-pregnancy measures of endothelial dysfunction and arterial stiffness. STUDY DESIGN: Prospective cohort; Data for 847 women female participants in the Cardiovascular Risk in Young Finns study were linked with the national birth registry. Preterm birth (<37weeks), low birthweight (<2500g), small-for-gestational-age (weight <10th percentile for gestational age), and hypertensive disorders of pregnancy were examined as predictors of later vascular measures...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29152651/age%C3%A2-related-differences-in-serum-mfg%C3%A2-e8-tgf%C3%A2-%C3%AE-1-and-correlation-to-the-severity-of-atherosclerosis-determined-by-ultrasound
#3
Huiying Zhao, Huanhuan Zhang, Xiujiao Qin
Atherosclerosis (AS) is an age‑related inflammatory disease. Globule‑epidermal growth factor‑8 (MFG‑E8) and transforming growth factor-β1 (TGF‑β1) are involved in the pathogenesis of AS. However, age‑related changes in circulating levels of MFG‑E8 and TGF‑β1, and their correlation with the severity of AS is not well‑characterized. In this study, we investigated age‑related changes in serum levels of MFG‑E8, TGF‑β1 and examined their association with the severity of AS. Sixty healthy volunteers were divided into young, middle‑age and old‑age groups...
October 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29151492/determinants-of-the-change-in-arterial-stiffness-in-peritoneal-dialysis-patients
#4
Mitsutaka Nakahigashi, Hiroyasu Tsukaguchi, Satoshi Morimoto, Chikara Nakano, Hiroko Ueda, Kazunori Someya, Makiko Kusabe, Sanae Kikuchi, Takanobu Imada, Ichiro Shiojima
Arterial stiffness is an important risk factor for cardiovascular disease (CVD) in patients with end-stage renal failure. However, little is known about the factors that contribute to arterial rigidity in peritoneal dialysis (PD) patients. The aim of this study was to define the pattern and determinants of the longitudinal change in arterial stiffness after PD initiation.Arterial stiffening was estimated for 46 PD patients by using brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (cIMT)...
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29151018/study-of-the-nlrp3-inflammasome-component-genes-and-downstream-cytokines-in-patients-with-type-2-diabetes-mellitus-with-carotid-atherosclerosis
#5
Junli Lee, Jing Wan, Linyun Lee, Changhua Peng, Hailong Xie, Chengbin Lee
BACKGROUND: A role for the NLRP3 inflammasome has been reported in various diseases, such as diabetes mellitus, atherosclerosis (AS), nephropathy, rheumatism, and others, although limited information is available concerning the role of the NLRP3 inflammasome, interleukin-1β (IL-1β) and interleukin-18 (IL-18) in patients with type 2 diabetes mellitus (T2DM) and carotid atherosclerosis (CAS). Therefore, this cross-sectional study investigated these inflammatory components in patients with T2DM complicated with carotid atherosclerosis (T2DM + CAS)...
November 18, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29148586/a-dynamic-ultrasound-simulation-of-a-pulsating-three-layered-cca-for-validation-of-2d-wall-motion-and-blood-velocity-estimation-algorithms
#6
Xiao Hu, Yufeng Zhang, Guanghui Cai, Kexin Zhang, Li Deng, Lian Gao, Suya Han, Jianhua Chen
PURPOSE: A dynamic ultrasound simulation model for the common carotid artery (CCA) with three arterial layers for validation of 2D wall motion and blood velocity estimation algorithms is proposed in present study. This model describes layers with not only characteristics of echo distributions conforming to clinical ones, but also varying thicknesses, axial and radial displacements with pulsatile blood pressure during a cardiac cycle. METHODS: The modeling process is as follows: first, a geometrical model according with the clinical structure size of a CCA is built based on the preset layer thicknesses and the diameter of lumen...
November 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/29148412/psychological-comorbidities-associated-with-subclinical-atherosclerosis-in-greek-patients-with-primary-sj%C3%A3-gren-s-syndrome-a-potential-contribution-of-sleep-impairment
#7
Theofanis Karageorgas, Dimitrios Ioakeimidis, Clio P Mavragani
OBJECTIVES: Impaired sleep and psychological disorders are increasingly recognised as prevalent comorbidities in patients with primary Sjögren's syndrome (pSS), as well as important contributors of atherosclerosis in the general population. In the current study we sought to explore a potential role of psychological comorbidities in the pronounced atherosclerotic risk of pSS patients. METHODS: Fifty-nine pSS patients fulfilling the ACR/EULAR criteria completed specific validated questionnaires assessing fatigue, depression, anxiety and sleep disturbances...
November 14, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29142565/correlation-between-hyperhomocysteinemia-and-common-carotid-artery-intima-media-thickness-in-carbamazepine-treated-epileptic-patients-using-ultrasonography
#8
Shazia Bano, Nudrat Anwar Zuberi, Syed Munawar Alam
Objective: The objective was to assess the role of homocysteine in the development of atherosclerosis in common carotid artery in the carbamazepine treated epileptic patients. Methods: This study was conducted in the Department of Biochemistry, Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Center (JPMC), Karachi. Three hundred individuals, aged 34 ± 9.5 years were selected and divided into three groups. Each group comprised of 100 subjects labeled as Group-A (control group had healthy individuals), Group-B (newly diagnosed epileptic patients without antiepileptic therapy), Group-C (epileptic patients on Carbamazepine therapy, which was further subdivided into C-I having epileptic patients on Carbamazepine therapy less than 1 year n=33, C-II had epileptic patients on Carbamazepine therapy 1-2 years n = 33 and C-III comprised of epileptic patients on Carbamazepine therapy more than 2 years n = 34)...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29142027/underestimation-of-risk-of-carotid-subclinical-atherosclerosis-by-cardiovascular-risk-scores-in-patients-with-psoriatic-arthritis
#9
Jiayun Shen, Steven H Lam, Qing Shang, Chun-Kwok Wong, Edmund K Li, Priscilla Wong, Emily W Kun, Isaac T Cheng, Martin Li, Tena K Li, Tracy Y Zhu, Jack Jock-Wai Lee, Mimi Chang, Alex Pui-Wai Lee, Lai-Shan Tam
OBJECTIVE: To test the performances of established cardiovascular (CV) risk scores in discriminating subclinical atherosclerosis (SCA) in patients with psoriatic arthritis. METHODS: These scores were calculated: Framingham risk score (FRS), QRISK2, Systematic COronary Risk Evaluation (SCORE), 10-year atherosclerotic cardiovascular disease risk algorithm (ASCVD) from the American College of Cardiology and the American Heart Association, and the European League Against Rheumatism (EULAR)-recommended modified versions (by 1...
November 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29140571/is-overactive-bladder-microvasculature-disease-a-component-of-systemic-atheroscleorosis
#10
Ahmet Ozgur Yeniel, Ahmet Mete Ergenoglu, Reci Meseri, Erkan Kismali, Anıl Ari, Gulgun Kavukcu, Hikmet H Aydin, Handan Ak, Sevcan Atay, Ismail Mete Itil
AIMS: To evaluate the relationship between overactive bladder (OAB) and systemic atherosclerosis in a cohort of women. METHODS: In this case-control study, we assessed atherosclerosis indicators, such as Framingham risk scores and carotid and femoral artery intima-media thickness, and evaluated possible bladder wall responses to atherosclerosis using endovaginal color Doppler ultrasound and the detection of urinary cytokines in women with OAB and in controls. Quantitative assessment of blood perfusion at the bladder neck was performed using a method that allows for the dynamic monitoring of flow in a predefined region of interest at every point of the cardiac cycle...
November 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29139080/a-review-of-insulin-resistance-in-type-1-diabetes-is-there-a-place-for-adjunctive-metformin
#11
REVIEW
Gagan Priya, Sanjay Kalra
There is a rising trend of overweight and obesity among individuals with type 1 diabetes. This is often associated with insulin resistance, increased insulin dose requirements and poor glycemic control. Insulin resistance is also seen during puberty and is strongly related to increased risk of cardiovascular disease. The role of metformin as an adjunct to ongoing intensive insulin therapy in type 1 diabetics has been evaluated in several randomized trials, including the recently concluded T1D Exchange Network trial in adolescents and the REMOVAL trial in adults...
November 14, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29138200/assessing-the-consequences-of-gestational-diabetes-mellitus-on-offspring-s-cardiovascular-health-mysweetheart-cohort-study-protocol-switzerland
#12
Stefano Di Bernardo, Yvan Mivelaz, Adina Mihaela Epure, Yvan Vial, Umberto Simeoni, Pascal Bovet, Sandrine Estoppey Younes, Arnaud Chiolero, Nicole Sekarski
INTRODUCTION: Gestational diabetes mellitus (GDM) is a state of glucose intolerance with onset during pregnancy. GDM carries prenatal and perinatal risks as well as long-term risks for the mother and her child. GDM may be involved in the foetal programming of long-term cardiovascular health. However, evidence is sparse and the effect of GDM on cardiovascular health is unknown. To address these issues, we will conduct MySweetHeart Cohort study. The objectives are to assess the effect of GDM on offspring's cardiovascular health early in life by using surrogate markers of cardiovascular disease and atherosclerosis...
November 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29137477/circulating-lipopolysaccharide-binding-protein-and-carotid-intima-media-thickness-in-obstructive-sleep-apnea
#13
I Trojova, M Kozarova, D Petrasova, Z Malachovska, I Paranicova, P Joppa, R Tkacova
Circulating lipopolysaccharide-binding protein (LBP), a metabolic endotoxemia marker, was identified as an independent predictor of atherosclerosis. Although increases in carotid intima-media thickness (CIMT) were repeatedly reported in obstructive sleep apnea (OSA), neither the role of OSA in metabolic endotoxemia nor of LBP in early atherosclerosis were explored in patients with OSA. At a tertiary university hospital we investigated the relationships between OSA, LBP and CIMT in 117 men who underwent full polysomnography and CIMT assessment by B-mode ultrasound...
November 10, 2017: Physiological Research
https://www.readbyqxmd.com/read/29135056/a-systematic-review-of-the-associations-between-hiv-hcv-coinfection-and-biomarkers-of-cardiovascular-disease
#14
REVIEW
Olatokunbo Osibogun, Oluseye Ogunmoroti, Erin D Michos, Erica S Spatz, Babatunde Olubajo, Khurram Nasir, Wasim Maziak
The incidence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection has been increasing with over 10 million people affected globally. The role biomarkers play as predictors of cardiovascular disease (CVD) risk among coinfected individuals is not well defined. We aimed to systematically review current evidence describing CVD biomarkers among individuals with HIV/HCV coinfection. We searched EMBASE, CINAHL, Google Scholar, PubMed, and Web of Science from inception to June 2017. MeSH terms and keywords were used to identify studies with information on HIV/HCV coinfection and CVD biomarkers (structural, functional, and serological) such as carotid intima-media thickness (CIMT), endothelial markers, C-reactive protein (CRP), homocysteine, and lipids...
November 14, 2017: Reviews in Medical Virology
https://www.readbyqxmd.com/read/29132058/clinical-significance-of-the-coexistence-of-carotid-artery-plaque-and-white-matter-disease-in-patients-with-symptomatic-cerebral-infarction
#15
Mami Ishikawa, Hitoshi Sugawara, Toshiyuki Tsuji, Mutsumi Nagai, Gen Kusaka, Heiji Naritaka
OBJECTIVES: Symptomatic cerebral infarction (CI) can occur in patients without main cerebral artery stenosis or occlusion. This study investigated the unique features of carotid artery plaque and white matter disease (WMD) in patients with symptomatic CI and transient ischemic attack (TIA) but without stenosis or occlusion of a main cerebral artery. PATIENTS AND METHODS: We studied 647 patients who underwent both carotid ultrasound examination and brain magnetic resonance images...
December 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29124969/the-gut-mycobiome-composition-is-linked-to-carotid-atherosclerosis
#16
M R Chacón, J Lozano-Bartolomé, M Portero-Otín, M M Rodríguez, G Xifra, J Puig, G Blasco, W Ricart, F J Chaves, J M Fernández-Real
The mycobiotic component of the microbiota comprises an integral, yet under-researched, part of the gastrointestinal tract. Here, we present a preliminary study of the possible contribution of gut mycobiota to sub-clinical atherosclerosis in a well-characterised group of obese and non-obese subjects in association with the Framingham Risk Score (FRS) and carotid intima-media thickness (cIMT). From all taxa identified, the relative abundance of the phylum Zygomycota, comprising the family Mucoraceae and genus Mucor, was negatively associated with cIMT and this association remained significant after controlling for false discovery rate...
November 10, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/29123443/plasma-atherogenic-index-is-an-independent-indicator-of-subclinical-atherosclerosis-in-systemic-lupus-erythematosus
#17
Ali Ugur Uslu, Adem Kucuk, Abdullah Icli, Erkan Cure, Davut Sakiz, Sevket Arslan, Rabia Aydogan Baykara
Objective: Systemic lupus erythematosus (SLE) is characterized by chronic inflammation. Plasma atherogenic index (PAI) is a valuable marker for the cardiovascular disease and cardiac risk. The aim of this study was to evaluate the role and clinical use of PAI in atherosclerosis and the cardiac risk in SLE patients. Materials and Methods: We included 56 female SLE patients who were selected according to the American College of Rheumatology (1997) diagnosis criteria...
October 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29123368/atherosclerosis-is-associated-with-a-higher-risk-of-hepatic-steatosis-in-hiv-infected-patients
#18
REVIEW
A Zizza, M Guido, M R Tumolo, A De Donno, F Bagordo, P Grima
Introduction: Cardiovascular Diseases (CD) have emerged as a leading cause of morbidity and mortality in HIV population. Some studies have reported higher carotid Intima Media Thickness (c-IMT), a measure of subclinical atherosclerosis (AT), in this cohort of patients. Methods: Here, we evaluate the role of Hepatic Steatosis (HS) as likely marker for AT in 128 HIV-infected patients without hepatitis C infection. c-IMT has been detected non-invasively by carotid ultrasonography to assess the progression of AT...
September 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/29121596/the-impact-of-long-term-moderate-and-heavy-alcohol-consumption-on-incident-atherosclerosis-among-persons-living-with-hiv
#19
N E Kelso-Chichetto, M Plankey, D S Sheps, A G Abraham, X Chen, S Shoptaw, R C Kaplan, W S Post, R L Cook
BACKGROUND: Level of alcohol consumption is associated with differential risk of atherosclerosis, but little research has investigated this association among HIV+ persons. We evaluated the association between long-term alcohol use and incident atherosclerosis among HIV+ persons. METHODS: We utilized data from HIV+ participants of the Women's Interagency HIV Study (n=483) and the Multicenter AIDS Cohort Study (n=305) without history of cardiovascular disease. Atherosclerosis was assessed two times by B-mode carotid artery ultrasound imaging from 2004 to 2013...
October 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29120994/inhaled-corticosteroids-in-asthma-promoting-or-protecting-against-atherosclerosis
#20
Michał Podgórski, Maciej Kupczyk, Piotr Grzelak, Małgorzata Bocheńska-Marciniak, Michał Polguj, Piotr Kuna, Ludomir Stefańczyk
BACKGROUND Bronchial asthma is an inflammatory disease of the respiratory system. However, it may also induce systemic effects. Although reports suggest patients with asthma are at increased risk of cardiovascular events, the association between asthma and atherosclerosis is unclear. The aim of the present study was to compare the progression of atherosclerosis between patients with asthma treated with inhaled corticosteroids and healthy controls. MATERIAL AND METHODS In 102 adult patients with asthma, markers of arterial stiffness (pulse wave velocity and augmentation index) were evaluated by applanation tonometry...
November 9, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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