Read by QxMD icon Read

Carotid intima media thickness

Nobutaka Noto, Akiko Komori, Mamoru Ayusawa, Shori Takahashi
Kawasaki disease (KD) is a systemic vasculitis with a predilection for damage to the coronary arteries. In the acute phase, clinical decision making for KD relies on the measurements of the coronary z-score obtained by 2-dimensional echocardiography (2DE). In the convalescent phase, KD patients with coronary artery abnormalities (CAAs) eventually show arteriosclerotic vascular remodeling characterized by marked intimal proliferation and neoangiogenesis after KD vasculitis, which often induces myocardial ischemia...
February 2018: Cardiovascular Diagnosis and Therapy
Sarah A Aroner, Manja Koch, Kenneth J Mukamal, Jeremy D Furtado, James H Stein, Matthew C Tattersall, Robyn L McClelland, Majken K Jensen
BACKGROUND: Apolipoprotein C-III (apoC-III), a small proinflammatory protein present on 6% to 7% of high-density lipoprotein (HDL) particles, defines a subspecies of HDL adversely associated with coronary heart disease in primarily white cohorts. In a multi-ethnic population free of clinical cardiovascular disease, we evaluated the relationship between apoC-III-defined HDL subspecies and subclinical markers of atherosclerotic pathology. METHODS AND RESULTS: We investigated cross-sectional associations between apolipoprotein A-I concentrations of apoC-III-defined HDL subspecies, measured via ELISA and imaging measures of subclinical atherosclerosis, among 4659 participants in the MESA (The Multi-Ethnic Study of Atherosclerosis) at baseline (2000-2002)...
March 14, 2018: Journal of the American Heart Association
Kavitha Gopalan, Surjit Singh, Pandiarajan Vignesh, Anju Gupta, Manojkumar Rohit, Savita Verma Attri
BACKGROUND: Kawasaki disease (KD) has a predilection to involve coronary arteries, leading to several long-term cardiovascular sequelae. Apart from coronary artery abnormalities, children with KD are also prone to develop premature atherosclerosis, endothelial dysfunction, and lipid abnormalities. Some of these complications may occur even in children who have received appropriate treatment with intravenous immunoglobulin in the acute phase. METHODS: In 2009, we had studied carotid intima-media thickness (cIMT) and lipid profile in 27 children with KD at least 1 year after the acute episode...
March 13, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Elena Bellosta Diago, Jesús Pérez-Pérez, Sonia Santos Lasaosa, Alejandro Viloria Alebesque, Saül Martínez-Horta, Jaime Kulisevsky, Javier López Del Val
Cardiovascular events are a major cause of early death in the Huntington's disease (HD) population. Dysautonomia as well as deterioration of circadian rhythms can be detected early in the disease progression and can have profound effects on cardiac health. The aim of the present study was to determine if HD patients and premanifest mutation carriers present a higher risk of cardiovascular disease (CVD) than non-mutation carrying controls METHODS: Prospective, cross-sectional, multicentre study of 38 HD mutation carriers (23 premanifest and 15 early-stage patients) compared to 38 age- and gender-matched healthy controls...
March 14, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Yupeng Wu, Dandan Sun, Bin Wang, Yanfeng Li, Yi Ma
Objectives The relationship of depressive symptoms and subclinical atherosclerosis remains controversial. We performed a systematic review and meta-analysis to evaluate the effect of depressive symptoms on the functional and structural markers of subclinical atherosclerosis as measured by carotid intima-media thickness (IMT), pulse wave velocity (PWV) and flow-mediated vasodilation (FMD). Methods A systematic literature search was performed electronically. Studies relating IMT, PWV or FMD to depressive symptoms were included...
January 1, 2018: European Journal of Preventive Cardiology
Stefanie R van Mil, L Ulas Biter, Gert-Jan M van de Geijn, Erwin Birnie, Martin Dunkelgrun, Jan N M IJzermans, Noelle van der Meulen, Guido H H Mannaerts, Manuel Castro Cabezas
INTRODUCTION: Type 2 diabetes mellitus (T2DM) and obesity are both related to increased risk of cardiovascular disease and mortality. Early atherosclerotic vascular changes can be detected by non-invasive tests like carotid artery intima-media thickness (cIMT) and pulse wave velocity (PWV). Both cIMT and PWV are significantly impaired in T2DM patients and in obese patients, but the additional effect of T2DM on these vascular measurements in obese subjects has not been evaluated. METHODS: Two hundred morbidly obese patients with or without T2DM were enrolled in a prospective cohort study and underwent extensive laboratory testing, including cIMT and PWV measurements...
March 13, 2018: Obesity Surgery
Ayse Selcan Koc, Ferıde Fatma Gorgulu, Yurdaer Donmez, Yahya Kemal Icen
PURPOSE: There are limited data about increased aortic intima-media thickness (A-IMT) in the presence of subclinical target organ damage in hypertensive (HT) patients. In this study, we aimed to determine the frequency of increased A-IMT, the parameters determining increased A-IMT, and the relationship between increased A-IMT and other vascular IMT measurements. MATERIALS AND METHODS: We prospectively included 265 patients (mean age 54.1 ± 10.6 years, male/female 91/174) with essential HT...
March 13, 2018: Journal of Medical Ultrasonics
Rodolfo A Kolliker Frers, Vanesa Cosentino, Julia Tau, Eduardo M Kerzberg, Adriana Urdapilleta, Monica Chiocconi, Nora Kogan, Matilde Otero-Losada, Francisco Capani
Studies on the inflammatory burden in recent-onset psoriatic arthritis (PsA) patients without conventional cardiovascular risk factors (CVRFs) are not available. This preliminary study focuses on cardiovascular risk in cutaneous psoriasis (CPs) and recent-onset PsA patients. Blood biochemistry (glucose, cholesterol, uric acid, lipid profile and apolipoprotein B) was analyzed using standard kits. Proatherogenic inflammation markers, C-reactive protein (CRP) and interleukin-6 (IL-6), and endothelial activators monocyte chemoattractant protein-1 (MCP-1) and soluble intercellular adhesion molecule-1 (sICAM-1), were determined by enzyme-linked immunosorbent assay...
2018: Frontiers in Immunology
Theodoros Kelesidis, Carlee B Moser, Elizabeth Johnston, James H Stein, Michael P Dube, Otto O Yang, Grace A McComsey, Judith S Currier, Todd T Brown
BACKGROUND: The contributions of the Receptor activator of nuclear factor kappa-B ligand (RANKL)/osteoprotegerin (OPG) axis to cardiovascular and bone disease in treated HIV-1 infection is not well-defined. SETTING: Prospective, observational, longitudinal study. METHODS: In a subset analysis of a prospective randomized clinical trial, 234 HIV-1-infected antiretroviral therapy (ART)-naïve participants received tenofovir-emtricitabine plus either atazanavir/ritonavir, darunavir/ritonavir, or raltegravir and achieved plasma HIV-1 RNA <50 copies/ml by week 24 and thereafter...
March 12, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Bin Wu, Jingshan Huang, Keisuke Fukuo, Kazuhisa Suzuki, Gen Yoshino, Tsutomu Kazumi
The aim of this study was to assess whether the gender-specific pattern of fat mass (FM) distribution is related to gender differences in cardiometabolic risk factors. 207 healthy middle-aged Japanese were included in the study. We measured FM in the total body, trunk, and lower-body with dual-energy X-ray absorptiometry (DXA). The percentage of trunk FM (TFM) and lower-body FM (LFM) is noted as %TFM and %LFM, respectively. Other measurements included glucose and insulin during oral glucose tolerance test (OGTT), leptin, adiponectin, plasminogen activator inhibitor-1 (PAI-1), tumor necrosis factor- α (TNF- α ), C-reactive protein (CRP), and systemic oxidative stress marker...
2018: International Journal of Endocrinology
Caitlynd Myburgh, Hugo W Huisman, Catharina M C Mels
Oxidative stress has been implicated in the development of hypertension, arterial stiffness and atherosclerosis. Optimal functioning of the enzymatic antioxidant system is central to prevent increased oxidative stress and its consequences. We aimed to investigate the relationships of ambulatory blood pressure and carotid intima-media thickness with enzyme activities of the glutathione cycle in 396 young, black and white South Africans of the African-PREDICT study. Ambulatory blood pressure and carotid intima-media thickness were measured and glutathione peroxidase and glutathione reductase activities were analyzed...
March 12, 2018: Journal of Human Hypertension
Hirotomo Yamanashi, Jun Koyamatsu, Mako Nagayoshi, Yuji Shimizu, Shin-Ya Kawashiri, Hideaki Kondo, Shoichi Fukui, Mami Tamai, Shuntaro Sato, Katsunori Yanagihara, Atsushi Kawakami, Takahiro Maeda
The association between human T-cell leukemia virus-1 (HTLV-1) and atherosclerosis remains to be determined. This case-control study aimed to investigate this association as measured by carotid intima-media thickness (CIMT). HTLV-1 infection was positively associated with CIMT, independent of atherosclerotic risks.
February 26, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Rector Arya, Agustin Escalante, Vidya S Farook, Jose F Restrepo, Daniel F Battafarano, Marcio Almeida, Mark Z Kos, Marcel J Fourcaudot, Srinivas Mummidi, Satish Kumar, Joanne E Curran, Christopher P Jenkinson, John Blangero, Ravindranath Duggirala, Inmaculada Del Rincon
Carotid Intima-media thickness (CIMT) and plaque are well established markers of subclinical atherosclerosis and are widely used for identifying subclinical atherosclerotic disease. We performed association analyses using Metabochip array to identify genetic variants that influence variation in CIMT and plaque, measured using B-mode ultrasonography, in rheumatoid arthritis (RA) patients. Data on genetic associations of common variants associated with both CIMT and plaque in RA subjects involving Mexican Americans (MA) and European Americans (EA) populations are presented in this article...
April 2018: Data in Brief
Alberto Lo Gullo, Javier Rodríguez-Carrio, Caterina Oriana Aragona, Giuseppe Dattilo, Concetta Zito, Ana Suárez, Saverio Loddo, Marco Atteritano, Antonino Saitta, Giuseppe Mandraffino
BACKGROUND AND AIMS: Cardiovascular (CV) morbidity is increased in inflammatory joint diseases (IJD), as rheumatoid (RA) and psoriatic arthritis (PsA). Whereas increased prevalence of subclinical atherosclerosis has been reported in these conditions, whether an early myocardial functionality is also impaired remains unknown. The aim of this study was to evaluate the myocardial functionality by speckle-tracking echocardiography (STE) in recent onset RA and PsA patients and its potential associations with the levels of circulating CD34 +  cells, vitamin D, and with disease activity...
March 2, 2018: Atherosclerosis
Eugenia Gkaliagkousi, Panagiota Anyfanti, Sophia Chatzimichailidou, Areti Triantafyllou, Antonios Lazaridis, Spyros Aslanidis, Stella Douma
Predictors of adverse cardiovascular outcomes include elevated nighttime systolic blood pressure (SBP) and a non-dipping pattern. We investigated whether these factors correlate with systemic inflammation, cardiovascular risk, and markers of central and peripheral vascular damage in rheumatoid arthritis (RA), a disease characterized by excess cardiovascular risk. Twenty-four-hour ambulatory blood pressure monitoring was applied in patients and controls. Vascular assessments included measurement of arterial stiffness (pulse wave velocity) and carotid atherosclerosis (carotid intima-media thickness)...
March 9, 2018: Journal of Human Hypertension
Jialin He, Pingan Chen, Yishan Luo, Lushan Chen, Shaonan Li, Yichao Pan, Shenshen Fu
BACKGROUND: Carotid artery plaque is associated with coronary artery disease (CAD). Besides the presence of plaque, plaque characteristics is also related to the severity of CAD. So the characteristic difference of carotid plaque may affect this assessment role. However, it is unclear whether the maximum carotid plaque area can reflect the extents and severity of CAD. METHODS: We enrolled 388 consecutive CAD patients and 45 controls, and 204 patients were studied after excluding 184 patients without carotid plaque or coronary angiogram...
March 8, 2018: International Angiology: a Journal of the International Union of Angiology
Lucia Taramasso, Michele Mirabella, Francesca Cappadona, Barbara Bonino, Niccolo Riccardi, Giovanni Cenderello, Giuseppe Vittorio De Socio, Claudio Viscoli, Francesca Viazzi, Antonio Di Biagio
OBJECTIVES: to compare the prevalence of target-organ damage (TOD), defined as carotid plaque, or intima media thickness, cIMT, >0.9 mm, and that of increased renal resistive index (RRI), among HIV-1-infected patients (PLWHIV) and uninfected hypertensive patients (HT-non HIV). METHODS: PLWHIV aged > 40 years and virologically suppressed were matched with pair-age, sex and BMI HT-non HIV. Patients on antihypertensive treatment were excluded. All patients' cIMT and RRI were evaluated with ultrasonography...
March 7, 2018: Current Hypertension Reviews
J Sothornwit, W Somboonporn, S Soontrapa, S Kaewrudee, J Wongwiwatchai, S Soontrapa
OBJECTIVES: To explore the difference in carotid intima-media thickness (CIMT) between postmenopausal women with and without osteoporosis and the risk of elevated CIMT and plaque presentation. METHOD: A cross-sectional study was conducted including 46 postmenopausal women with osteoporosis and 45 non-osteoporotic postmenopausal women. CIMT was measured using B-mode ultrasound. RESULTS: There was no statistically significant difference in mean CIMT between postmenopausal women with osteoporosis and those without osteoporosis (p > 0...
March 9, 2018: Climacteric: the Journal of the International Menopause Society
Roshan Kumar Mahat, Neelima Singh, Akshara Gupta, Vedika Rathore
Prediabetes is considered as a risk factor for the development of diabetes mellitus and cardiovascular disease. The present study was conducted with the aim of finding out the relationship between oxidative DNA damage and carotid intima media thickness for the prediction of cardiovascular disease in prediabetic subjects. The study included 100 prediabetic subjects and 100 normal individuals as controls. In both cases and controls, 8-OHdG was measured by ELISA, and CIMT was measured by B mode ultrasonography...
March 7, 2018: Journal of Cardiovascular Development and Disease
Smitha R Vidi
PURPOSE OF REVIEW: Hypertension is an independent risk factor for progression of chronic kidney disease (CKD) in children. Children with early CKD develop hypertension secondary to renal disease. This review aims to highlight recent advances that help us better understand the current role of hypertension in progression of CKD in children. RECENT FINDINGS: There is increasing evidence that children with CKD who have hypertension develop early atherosclerosis and cardiac adaptive changes...
April 2018: Current Opinion in Pediatrics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"