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https://www.readbyqxmd.com/read/28445881/absence-of-decline-of-kidney-function-in-human-immunodeficiency-virus-infected-patients-under-routine-clinical-management
#1
Julie Boucquemont, Sylvie Lawson-Ayayi, Claire Rigothier, Fabrice Bonnet, Cécile Proust-Lima, Didier Neau, Carine Greib, Ghada Miremont-Salamé, François Dabis, Michel Dupon, Frédéric-Antoine Dauchy
BACKGROUND: Since the introduction of antiretroviral therapy (ART), human immunodeficiency virus (HIV)-infected patients have a drastically improved prognosis but at the same time they are also more affected by non-HIV related complications, such as chronic kidney disease. The objective of our study was to investigate the effect of proteinuria and tenofovir (TDF)-containing ART regimens on the temporal evolution of estimated glomerular filtration rate (eGFR). METHODS: Between April 2008 and October 2012, we enrolled 395 patients with a complete renal evaluation among patients from the ANRS C03 Aquitaine cohort, a prospective hospital-based cohort of HIV-1-infected patients under routine clinical management in southwestern France...
April 26, 2017: Nephron
https://www.readbyqxmd.com/read/28406316/five-year-follow-up-of-persons-with-brain-injury-entering-the-french-vocational-and-social-rehabilitation-programme-ueros-return-to-work-life-satisfaction-psychosocial-and-community-integration
#2
M Cogné, L Wiart, A Simion, P Dehail, J-M Mazaux
BACKGROUND: Social and vocational reintegration of persons with brain injury is an important element in their rehabilitation. AIMS: To evaluate the 5-year outcome of persons with brain injury included in 2008 in the Aquitaine Unit for Evaluation, Training and Social and Vocational Counselling programme (UEROS). METHOD: 57 persons with brain injury were recruited from those who completed the 2008 UEROS programme. Five years later, an interview was done to assess family and vocational status, autonomy and life satisfaction...
April 13, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28403966/-intrauterine-blood-transfusion-status-report-of-4years-of-practice-in-france-2011-2014
#3
A Girault, S Friszer, E Maisonneuve, L Guilbaud, A Cortey, J-M Jouannic
OBJECTIVES: The aim of our study was to evaluate in utero blood transfusion's (IUT) performed in France, among the French prenatal diagnosis centers in order to study the etiology of severe anemia requiring IUT. METHODS: We conducted a national retrospective descriptive study between 2011 and 2014. The data were collected using a survey sent by email to all French prenatal diagnosis centers. RESULTS: Among the 49 centers, 18 (38 %) had performed at least one IUT during the study period...
February 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28386883/simulating-changes-in-cropping-practices-in-conventional-and-glyphosate-resistant-maize-ii-%C3%A2-weed-impacts-on-crop-production-and-biodiversity
#4
Nathalie Colbach, Henri Darmency, Alice Fernier, Sylvie Granger, Valérie Le Corre, Antoine Messéan
Overreliance on the same herbicide mode of action leads to the spread of resistant weeds, which cancels the advantages of herbicide-tolerant (HT) crops. Here, the objective was to quantify, with simulations, the impact of glyphosate-resistant (GR) weeds on crop production and weed-related wild biodiversity in HT maize-based cropping systems differing in terms of management practices. We (1) simulated current conventional and probable HT cropping systems in two European regions, Aquitaine and Catalonia, with the weed dynamics model FLORSYS; (2) quantified how much the presence of GR weeds contributed to weed impacts on crop production and biodiversity; (3) determined the effect of cultural practices on the impact of GR weeds and (4) identified which species traits most influence weed-impact indicators...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28328797/activation-senescence-and-inflammation-markers-in-hiv-patients-association-with-renal-function
#5
Alexandra Ozanne, Pierre Duffau, Frédéric-Antoine Dauchy, Claire Rigothier, Cécile Terrien, Estibaliz Lazaro, Charles Cazanave, Sylvie Lawson-Ayayi, Fabrice Bonnet, Patrick Blanco, Linda Wittkop, Isabelle Pellegrin
OBJECTIVES: To assess the association among immune activation, immune senescence, inflammation biomarkers and renal function measured by estimated glomerular filtration rate (eGFR) at inclusion and its evolution over a 3-year follow-up in HIV-infected patients with undetectable viral load. DESIGN: The Chronic Immune Activation and Senescence (CIADIS) substudy consecutively included patients between October 2011 and May 2013 enrolled in the ANRS CO3 Aquitaine observational cohort...
May 15, 2017: AIDS
https://www.readbyqxmd.com/read/28324251/simulating-changes-in-cropping-practises-in-conventional-and-glyphosate-tolerant-maize-i-effects-on-weeds
#6
Nathalie Colbach, Alice Fernier, Valérie Le Corre, Antoine Messéan, Henri Darmency
Herbicide-tolerant (HT) crops such as those tolerant to glyphosate simplify weed management and make it more efficient, at least at short-term. Overreliance on the same herbicide though leads to the spread of resistant weeds. Here, the objective was to evaluate, with simulations, the impact on the advent of glyphosate resistance in weeds of modifications in agricultural practises resulting from introducing HT maize into cropping systems. First, we included a single-gene herbicide resistance submodel in the existing multispecific FLORSYS model...
April 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28284287/-even-the-best-law-will-never-replace-reflection-in-the-field
#7
Jean-Pierre Bouchard
Implemented in 2006 by the French minister for health, the resource centres for people working with sex offenders (CRIAVS) provide support for professionals and non-professionals, concerned with transgressive sexual behaviour. They offer tools for legal, health and social professionals to facilitate the supervision of sex offenders. Florent Cochez, a psychiatrist and medical examiner, manager of the Aquitaine CRIAVS, describes in this interview the missions of these regional structures, their link with court-ordered therapy and his practice...
March 2017: Soins. Psychiatrie
https://www.readbyqxmd.com/read/28262371/-cooperation-according-to-french-law-hospital-patients-health-and-territories-pharmacists-involvement-in-aquitaine-region
#8
M d'Elbée, M Baumevieille, C Dumartin
BACKGROUND: In 2009, the French Act "Hospital, Patients, Health and Territories" (loi "Hôpital, Patients, Santé et Territoires") reorganized the outpatient care pathway and defined missions aimed at improving cooperation between pharmaceutical and medical professionals. Five years later, we conducted a survey among community pharmacists in order to assess the appropriation of these missions and the way cooperation was implemented. We also aimed to investigate factors that could hamper or ease the development of these activities in order to identify actions needed to improve pharmacists' involvement...
March 2, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28125043/comparison-of-aquitaine-and-rioja-red-wines-characterization-of-their-phenolic-composition-and-evolution-from-2000-to-2013
#9
Cindy Quaglieri, Noelia Prieto-Perea, Luis Angel Berrueta, Blanca Gallo, Zurine Rasines-Perea, Michael Jourdes, Pierre-Louis Teissedre
Wine chemical analysis was carried out on 194 commercial blended red wines produced by two major wine-growing areas-the Aquitaine (France) and Rioja (Spain) regions-in order to compare the wines of both regions. Anthocyanins and derived pigments, tannins and derivatives were identified and quantified by HPLC-DAD-ESI-MS/MS (high pressure liquid chromatography coupled to diode array detector and mass spectrometry using the electrospray ionization interface). Mean degree of polymerization (mDP) was determined...
January 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28046052/integrative-analysis-of-immunological-data-to-explore-chronic-immune-t-cell-activation-in-successfully-treated-hiv-patients
#10
Marie-Quitterie Picat, Isabelle Pellegrin, Juliette Bitard, Linda Wittkop, Cécile Proust-Lima, Benoît Liquet, Jean-François Moreau, Fabrice Bonnet, Patrick Blanco, Rodolphe Thiébaut
OBJECTIVES: To unravel the complex relationships between cytomegalovirus-induced-, autoimmune-induced responses, microbial translocation and chronic immune activation (CIA) in successfully treated HIV-infected patients and to explore the mediating role of alpha-interferon in these processes. DESIGN: Cross-sectional study nested in the ANRS CO3 Aquitaine Cohort, a prospective hospital-based cohort of HIV-1-infected patients in South-Western France. METHODS: Patients initiated antiretroviral therapy between 2005 and 2008 and were treated with sustained virological suppression for at least two years...
2017: PloS One
https://www.readbyqxmd.com/read/27811708/bucardium-grateloupianum-n-sp-from-the-lower-miocene-of-aquitaine-with-%C3%A2-%C3%A2-taxonomic-comments-on-some-fossil-species-from-europe-bivalvia-cardiidae
#11
Rafael La Perna
The genus Bucardium J. E. Gray, 1853 has been widely used in the past literature, either for living and fossil cardiids, but only a single species was known, its type species B. ringens (Bruguière, 1789), living in the tropical waters of West Africa. Another species, from the Lower Miocene of the Aquitaine Basin, turned out to be undescribed, though known since the 19th century. It is herein described as Bucardium grateloupianum n. sp. The genus seems to have always had a low diversity and a tropical distribution...
October 26, 2016: Zootaxa
https://www.readbyqxmd.com/read/27676996/management-of-stroke-patients-by-general-practioners-an-observational-study
#12
Bertrand Glize, Étienne Santos, Sophie Broussy, Igor Sibon, Pierre-Alain Joseph, Patrick Dehail
OBJECTIVE: Post-stroke medical management, defined by national and international guidelines, involves many professionals, allowing optimal secondary prevention. The general practitioner is as a major player in this management. The improved of this management appears as the new challenge following the stroke Plan 2009-2014. The aim of this study was to evaluate the medical and paramedical management of patients in the year following a stroke. MATERIAL/PATIENTS AND METHODS: This was an observational study among general practitioners of stroke patients in Aquitaine...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27667130/breed-differences-of-bull-frozen-thawed-semen
#13
A Ntemka, G Tsousis, C Brozos, E Kiossis, C M Boscos, I A Tsakmakidis
The objective of this study was to investigate the quality of frozen-thawed semen from different bull breeds. Commercial frozen-thawed bull semen samples (26 per breed, 130 totally) of five breeds (Holstein [Η], Brown Swiss [BS], Limousin [L], Belgian Blue [BB], Blonde d' Aquitaine [BA]) were used. After thawing, each semen sample was subjected to thermal resistance test (TR) for 0.5 and 1 hr at 38°C and hypo-osmotic swelling test (HOST) for 1 hr at 150 mOsm at 37°C. Additionally, all samples were evaluated at times 0 hr (thawing), 0...
December 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27564716/multidisciplinary-care-management-has-a-positive-effect-on-paediatric-obesity-and-social-and-individual-factors-are-associated-with-better-outcomes
#14
C Carriere, C Cabaussel, C Bader, P Barberger-Gateau, P Barat, H Thibault
AIM: The RePPOP Aquitaine network, which was established in south-west France to prevent and treat paediatric obesity, has developed a multidisciplinary approach based on multicomponent lifestyle interventions and family-based actions. This study assessed the impact of its care management programme and investigated the factors associated with better outcomes. METHODS: The impact of the RePPOP care management programme was assessed by changes in the body mass index (BMI) Z score, between baseline and the end-of-care management...
November 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27461460/dynamic-models-for-estimating-the-effect-of-haart-on-cd4-in-observational-studies-application-to-the-aquitaine-cohort-and-the-swiss-hiv-cohort-study
#15
Mélanie Prague, Daniel Commenges, Jon Michael Gran, Bruno Ledergerber, Jim Young, Hansjakob Furrer, Rodolphe Thiébaut
Highly active antiretroviral therapy (HAART) has proved efficient in increasing CD4 counts in many randomized clinical trials. Because randomized trials have some limitations (e.g., short duration, highly selected subjects), it is interesting to assess the effect of treatments using observational studies. This is challenging because treatment is started preferentially in subjects with severe conditions. This general problem had been treated using Marginal Structural Models (MSM) relying on the counterfactual formulation...
March 2017: Biometrics
https://www.readbyqxmd.com/read/27364174/prevalence-of-cannabis-and-cocaine-consumption-in-french-fishermen-in-south-atlantic-region-in-2012-2013-and-its-policy-consequences
#16
Emmanuel Fort, Thierry Lassiège, Alain Bergeret
BACKGROUND: The aim of the study was to evaluate the use of cannabis and cocaine among fishermen followed in occupational medicine in the ports of Aquitaine and Charente-Maritime (Direction interrégionale de la mer Sud-Atlantique [DIRM-SA]). MATERIALS AND METHODS: Thousand fishermen could be recruited during medical regulatory examination by the occupational physicians and nurses of Occupational Health Department for Seamen. RESULTS: About 20% of fishermen were former smokers...
2016: International Maritime Health
https://www.readbyqxmd.com/read/27311913/factors-and-motivations-associated-with-use-of-e-cigarette-among-primary-care-patients-in-a-prospective-cohort-study-e-tac-study-protocol
#17
Shérazade Kinouani, Philippe Castéra, Catherine Laporte, François Pétrègne, Bernard Gay
INTRODUCTION: While the relationship between electronic cigarette use and smoking has often been studied, the association between electronic cigarette use and socioeconomic factors has received less attention. This is a study protocol aiming to describe the relationship between the consumption of psychoactive products (in particular: smoking) or some socioeconomic factors and the evolution of the use of electronic cigarette in primary healthcare over 1 year. METHODS AND ANALYSIS: Electronic cigarette, Tobacco, Alcohol and Cannabis (e-TAC) is a prospective multisite cohort study, including 473 patients at baseline and carrying out in general practices in the Aquitaine area (France)...
2016: BMJ Open
https://www.readbyqxmd.com/read/27200135/-safety-evaluation-of-anticancer-drugs-circuit-in-a-regional-hospital-in-tunisia
#18
Jihène Sahli, Meriam El Ghardallou, Iheb Bougmiza, Besma Henchiri, Manel Limam, Rim Mejdoub, Ali Mtiraoui, Thouraya Ajmi
INTRODUCTION: Nowadays, the circuit of drugs is a plague. This situation may cause serious harm to patients. In this context, we conducted a study with the aim to describe and evaluate the circuit of anticancer drugs in a Tunisian regional hospital. METHODS: This is an evaluative study of the risk of anticancer drugs, conducted over a period of 15 days during the year 2014 in the Department of Cancer Research of the Regional Hospital of Gafsa (Tunisia). The evaluation method is based on that conducted by the project "SECURIMED" and developed by the Coordination Committee of the Clinical Evaluation and Quality in Aquitaine (CCECQA) in France...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27131655/validation-of-modelled-imaging-plates-sensitivity-to-1-100-kev-x-rays-and-spatial-resolution-characterisation-for-diagnostics-for-the-petawatt-aquitaine-laser
#19
G Boutoux, D Batani, F Burgy, J-E Ducret, P Forestier-Colleoni, S Hulin, N Rabhi, A Duval, L Lecherbourg, C Reverdin, K Jakubowska, C I Szabo, S Bastiani-Ceccotti, F Consoli, A Curcio, R De Angelis, F Ingenito, J Baggio, D Raffestin
Thanks to their high dynamic range and ability to withstand electromagnetic pulse, imaging plates (IPs) are commonly used as passive detectors in laser-plasma experiments. In the framework of the development of the diagnostics for the Petawatt Aquitaine Laser facility, we present an absolute calibration and spatial resolution study of five different available types of IP (namely, MS-SR-TR-MP-ND) performed by using laser-induced K-shell X-rays emitted by a solid silver target irradiated by the laser ECLIPSE at CEntre Lasers Intenses et Applications...
April 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27050752/incidence-and-risk-factors-for-severe-bacterial-infections-in-people-living-with-hiv-anrs-co3-aquitaine-cohort-2000-2012
#20
Amandine Collin, Fabien Le Marec, Marie-Anne Vandenhende, Estibaliz Lazaro, Pierre Duffau, Charles Cazanave, Yann Gérard, François Dabis, Mathias Bruyand, Fabrice Bonnet
Severe non-AIDS bacterial infections (SBI) are the leading cause of hospital admissions among people living with HIV (PLHIV) in industrialized countries. We aimed to estimate the incidence of SBI and their risk factors in a large prospective cohort of PLHIV patients over a 13-year period in France. Patients followed up in the ANRS CO3 Aquitaine cohort between 2000 and 2012 were eligible; SBI was defined as a clinical diagnosis associated with hospitalization of ≥48 hours or death. Survival analysis was conducted to identify risk factors for SBI...
2016: PloS One
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