Amrita Bharat, Laura Mataseje, E Jane Parmley, Brent P Avery, Graham Cox, Carolee A Carson, Rebecca J Irwin, Anne E Deckert, Danielle Daignault, David C Alexander, Vanessa Allen, Sameh El Bailey, Sadjia Bekal, Greg J German, David Haldane, Linda Hoang, Linda Chui, Jessica Minion, George Zahariadis, Richard J Reid-Smith, Michael R Mulvey
Extended-spectrum β-lactamases (ESBLs) confer resistance to extended-spectrum cephalosporins, a major class of clinical antimicrobial drugs. We used genomic analysis to investigate whether domestic food animals, retail meat, and pets were reservoirs of ESBL-producing Salmonella for human infection in Canada. Of 30,303 Salmonella isolates tested during 2012-2016, we detected 95 ESBL producers. ESBL serotypes and alleles were mostly different between humans (n = 54) and animals/meat (n = 41). Two exceptions were blaSHV-2 and blaCTX-M-1 IncI1 plasmids, which were found in both sources...
July 2022: Emerging Infectious Diseases