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https://www.readbyqxmd.com/read/29055290/a-qualitative-meta-synthesis-examining-the-role-of-women-in-african-american-men-s-prostate-cancer-screening-and-treatment-decision-making
#1
REVIEW
Erin M Bergner, Emily K Cornish, Kenay Horne, Derek M Griffith
OBJECTIVE: Being an African American man is a risk factor for prostate cancer and there is little consensus about the utility of screening, early detection, and the efficacy of treatment for the disease. In this context, this systematic review examines the roles women, particularly wives, play in African American men's prostate cancer screening and treatment decision-making. METHODS: We searched OVID Medline (R), CINAHL (EBSCO), PsychInfo (EBSCO), PubMED, Cochrane Library, ERIC (Firstsearch) and Web of Science to identify peer-review articles published between 1980-2016 that reported qualitative data about prostate cancer screening, diagnosis, or treatment in African American men...
October 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29055268/early-age-of-e-cigarette-use-onset-mediates-the-association-between-impulsivity-and-e-cigarette-use-frequency-in-youth
#2
Krysten W Bold, Meghan E Morean, Grace Kong, Patricia Simon, Deepa R Camenga, Dana A Cavallo, Suchitra Krishnan-Sarin
BACKGROUND: Identifying risk factors for youth e-cigarette use is critical, given high rates of e-cigarette use and unknown health effects of long-term use. The current study examined whether an early age of onset of e-cigarette use mediates the association between impulsivity and e-cigarette frequency. METHODS: Cross-sectional survey data of e-cigarette users (n=927) were collected from 8 high schools in southeastern Connecticut. The sample was 44.7% female (mean age 16...
October 13, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055267/nature-differences-of-fulvic-acid-fractions-induced-by-extracted-sequence-as-explanatory-factors-for-binding-characteristics-of-cu-2
#3
Zhenrui Zhang, Changwei Lü, Jiang He, Manshu Gao, Boyi Zhao, Bin Zhou, Jing Guo, Haijun Zhou, Xiaoting Liu, Zhuoming Li, Wenjing Shi, Yongjie Jiao, Wenxi Zhao, Yu Zhang
The isolation of fulvic acid (FA) fractions with relatively homogeneity is a key to reveal the binding mechanisms between FA and heavy metals. In this work, nine FA fractions were obtained using sequential alkali extraction procedure and nature differences of the extracted FA fractions were considered as explanatory factors for binding characteristics of Cu(2+). The results indicate that the contents of carboxyl and phenolic groups decrease with increasing extractions along with an opposite trend for the content of nitrogen-containing groups...
October 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/29055260/swimming-exercise-reverses-cums-induced-changes-in-depression-like-behaviors-and-hippocampal-plasticity-related-proteins
#4
Weina Liu, Xiangli Xue, Jie Xia, Jiatong Liu, Zhengtang Qi
BACKGROUND: Stress-induced failed resilience of brain plasticity can contribute to the onset and recurrence of depression. Chronic stress has been reported to open windows of epigenetic plasticity in hippocampus. However, how hippocampal plasticity underlies depression-like behaviors and how it adapts in response to stress has not been addressed. The present study aimed to investigate the signaling mechanisms of CUMS affecting hippocampal plasticity-related proteins expression and the regulation of swimming exercise in mice...
October 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29055254/the-effect-of-visual-cues-on-performance-in-the-ultimatum-game-in-individuals-with-autism-spectrum-disorder
#5
Daisuke Ikuse, Masayuki Tani, Takashi Itahashi, Hiroki Yamada, Haruhisa Ohta, Teppei Morita, Gousuke Arai, Nobuyuki Saga, Takahiro Tokumasu, Marie Ohta, Ayaka Sato, Akira Iwanami
The Ultimatum Game (UG) allows for the assessment of altruistic behavior as well as the perception of fairness. We examined the effects of visual social cues (gaze of others), factors associated with autism, and trust on UG performance in typical adults (TAs) and individuals with autism spectrum disorder (ASD). We hypothesized that individuals with ASD would be less affected by visual social cues than TAs. We recruited 30 TAs and 30 individuals with ASD. Participants completed 30 trials of the UG, during which the visual background was altered to include either stylized eyespots, flowers, or a neutral background...
October 5, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29055237/mechanisms-of-action-during-a-dissonance-based-intervention-through-14-month-follow-up-the-roles-of-body-shame-and-body-surveillance
#6
Lisa S Kilpela, Katherine E Schaumberg, Lindsey B Hopkins, Carolyn B Becker
Objectification theory posits that internalization of societal perspectives about the female body leads to increased body surveillance, which can result in body-related shame and subsequent eating disorder (ED) behaviors. Preliminary research indicates that these associations may be complex in nature. This study examined temporal relations among body surveillance, body shame, and eating disorder symptoms in the context of a dissonance-based body image intervention and through 14-month follow-up. College women (N=285) completed assessments at baseline, post-intervention, and at 8-week, 8-month, and 14-month follow-up...
October 18, 2017: Body Image
https://www.readbyqxmd.com/read/29055207/hormonal-contraceptive-use-in-smokers-prevalence-of-use-and-associations-with-smoking-motives
#7
Alicia M Allen, Kim Lundeen, Lynn E Eberly, Sharon S Allen, Mustafa al'Absi, Myra Muramoto, Dorothy Hatsukami
INTRODUCTION: While endogenous sex hormones influence smoking-related outcomes, little is known about the role of hormonal contraceptives (HCs). This is despite dated estimates suggesting that HC use is prevalent among female smokers. Therefore, we sought to update estimates of the prevalence of HC use among female smokers and explore the association of HC use with various smoking motives (SMs). METHODS: This online cross-sectional survey recruited female smokers between the ages of 18-35...
October 13, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055206/simultaneous-stabilization-solidification-of-mn-2-and-nh4-n-from-electrolytic-manganese-residue-using-mgo-and-different-phosphate-resource
#8
Jiancheng Shu, Haiping Wu, Renlong Liu, Zuohua Liu, Bing Li, Mengjun Chen, Changyuan Tao
This study examined simultaneous stabilization and solidification (S/S) of Mn(2+) and NH4(+)-N from electrolytic manganese residue (EMR) using MgO and different phosphate resource. The characteristics of EMR NH4(+)-N and Mn(2+) S/S behavior, S/S mechanisms, leaching test and economic analysis, were investigated. The results show that the S/S efficiency of Mn(2+) and NH4(+)-N could reach 91.58% and 99.98%, respectively, and the pH value is 8.75 when the molar ratio of Mg:P is 3:1 and the dose of PM (MgO and Na3PO4·12H2O) is 8wt%...
October 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29055203/insight-into-the-heterogeneous-adsorption-of-humic-acid-fluorescent-components-on-multi-walled-carbon-nanotubes-by-excitation-emission-matrix-and-parallel-factor-analysis
#9
Chenghu Yang, Yangzhi Liu, Qiulin Cen, Yaxian Zhu, Yong Zhang
The heterogeneous adsorption behavior of commercial humic acid (HA) on pristine and functionalized multi-walled carbon nanotubes (MWCNTs) was investigated by fluorescence excitation-emission matrix and parallel factor (EEM- PARAFAC) analysis. The kinetics, isotherms, thermodynamics and mechanisms of adsorption of HA fluorescent components onto MWCNTs were the focus of the present study. Three humic-like fluorescent components were distinguished, including one carboxylic-like fluorophore C1 (λex/λem= (250, 310) nm/428nm), and two phenolic-like fluorophores, C2 (λex/λem= (300, 460) nm/552nm) and C3 (λex/λem= (270, 375) nm/520nm)...
October 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29055185/effect-of-the-solvent-on-the-conformational-behavior-of-the-alanine-dipeptide-deduced-from-md-simulations
#10
Jaime Rubio-Martinez, M Santos Tomas, Juan J Perez
In general, peptides do not exhibit a well-defined conformational profile in solution. However, despite the experimental blurred picture associated with their structure, compelling spectroscopic evidence shows that peptides exhibit local order. The conformational profile of a peptide is the result of a balance between intramolecular interactions between different atoms of the molecule and intermolecular interactions between atoms of the molecule and the solvent. Accordingly, the conformational profile of a peptide will change upon the properties of the solvent it is soaked...
October 12, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29055139/exploratory-study-of-impact-of-cancer-related-posttraumatic-stress-symptoms-on-diabetes-self-management-among-cancer-survivors
#11
Janey James, Yael T Harris, Ian M Kronish, Juan P Wisnivesky, Jenny J Lin
OBJECTIVE: Posttraumatic stress symptoms (PTSS) can be triggered by a diagnosis of a potentially life-threatening illness such as cancer. Little is known about the impact of cancer-related PTSS symptoms on self-management behaviors for comorbid chronic medical conditions such as diabetes mellitus (DM). METHODS: We recruited patients with DM and a recent diagnosis of early-stage cancer from two medical centers in New York City. Cancer-related PTSS were assessed using the Impact of Events scale (IES, score ≥26)...
October 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29055129/desmopressin-for-treating-nocturia-in-men
#12
REVIEW
Julia Han, Jae Hung Jung, Caitlin J Bakker, Mark H Ebell, Philipp Dahm
BACKGROUND: Nocturia is the bothersome symptom of awakening one or more times per night to void. Desmopressin is a commonly used medication for treating nocturia. OBJECTIVES: To assess the effects of desmopressin as compared to other interventions in the treatment of nocturia in men. SEARCH METHODS: We performed a comprehensive search of medical literature with no restrictions on the language of publication or publication status. The date of the latest search of all databases was August 2017...
October 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29055128/a-generalized-outflow-boundary-condition-impedance-model-for-non-invasive-prediction-of-ischemia-in-diseased-coronary-arteries
#13
Iyad A Fayssal, Fadl Moukalled, Samir Alam, Hussain Isma'eel
This paper reports on a new boundary condition formulation to model the total coronary myocardial flow and impedance characteristics of the myocardial vascular bed for any specific patient when considered for non-invasive diagnosis of fractional flow reserve (FFR). The developed boundary condition model inherits an implicit representation of the downstream truncated vascular bed and is based on integrating patient-specific physiologic parameters that can be non-invasively extracted for each patient to account for blood flow demand to the myocardium at rest and hyperemic conditions...
October 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29055123/disruption-of-behavior-and-brain-metabolism-in-artificially-reared-rats
#14
Elsa L Aguirre-Benítez, Mercedes G Porras, Leticia Parra, Jacquelina González-Ríos, Dafne F Garduño-Torres, Damaris Albores-García, Arturo Avendaño, Miguel A Ávila-Rodríguez, Angel I Melo, Ismael Jiménez-Estrada, Ma Eugenia Mendoza-Garrido, César Toriz, Daniel Diaz, Elizabeth Ibarra-Coronado, Karina Mendoza-Ángeles, Jesús Hernández-Falcón
Early adverse life-stress has been associated to behavioral disorders that can manifest as inappropriate or aggressive responses to social challenges. In this study, we analyzed the effects of artificial rearing on the open field and burial behavioral tests and on GFAP, c-Fos immunoreactivity and glucose metabolism measured in anxiety related brain areas. Artificial rearing of male rats was performed by supplying artificial milk through a cheek cannula and tactile stimulation, mimicking the mother's licking to rat pups from the 4(th) postnatal day until weaning...
October 21, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29055099/regulation-of-glycosaminoglycan-biogenesis-is-critical-for-sensitive-period-dependent-vocal-ontogeny
#15
Caitlin P Mencio, Vy My Tran, Maritza V Quintero, Mamoru Koketsu, Franz Goller, Balagurunathan Kuberan
In the brain, the extracellular matrix (ECM) plays a central role during neural development and thus modulates critical-period regulated behavioral ontogeny. The major components of the ECM are glycosaminoglycans (GAGs) including chondroitin sulfate (CS). However, the specific roles of GAGs in behavioral development are largely unknown. It has been shown that xylosides affect the biological functions of GAGs through modulating GAG biosynthesis. Particularly, xylosides affect GAG biosynthesis through priming of GAG chains (priming activity), competing with endogenous core proteins that carry GAG initiation sites (decoy activity), or both...
October 21, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29055086/acute-mitogen-activated-protein-kinase-1-2-inhibition-improves-functional-recovery-and-vascular-changes-after-ischemic-stroke-in-rat-monitored-by-9-4-t-magnetic-resonance-imaging
#16
Maryam Mostajeran, Friedrich Wetterling, Frank W Blixt, Lars Edvinsson, Saema Ansar
AIM: The aim was to evaluate the beneficial effect of early mitogen activated protein kinase (MEK)1/2 inhibition administered at a clinical relevant time-point using the transient middle cerebral artery occlusion model and a dedicated rodent magnetic resonance imaging system (9.4T) to monitor cerebrovascular changes non-invasively for two weeks. METHOD: Transient middle cerebral artery occlusion was induced in male rats for two hours followed by reperfusion. The specific MEK1/2 inhibitor U0126 was administered i...
October 21, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/29055080/matrix-approach-to-land-carbon-cycle-modeling-a-case-study-with-community-land-model
#17
Yuanyuan Huang, Xingjie Lu, Zheng Shi, David Lawrence, Charles Koven, Jianyang Xia, Zhenggang Du, Erik Kluzek, Yiqi Luo
The terrestrial carbon (C) cycle has been commonly represented by a series of C balance equations to track C influxes into and effluxes out of individual pools in earth system models (ESMs). This representation matches our understanding of C cycle processes well but makes it difficult to track model behaviors. It is also computationally expensive, limiting the ability to conduct comprehensive parametric sensitivity analyses. To overcome these challenges, we have developed a matrix approach, which reorganizes the C balance equations in the original ESM into one matrix equation without changing any modeled C cycle processes and mechanisms...
October 20, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29055047/species-specific-role-of-gene-adjacent-retroelements-in-human-and-mouse-gastric-carcinogenesis
#18
REVIEW
Mun-Gan Rhyu, Jung-Hwan Oh, Seung-Jin Hong
Helicobacter pylori (HP) infection promotes the recruitment of bone marrow stem cells into chronic gastritis lesions. Some of these marrow stem cells can differentiate into gastric epithelial cells and neoplastic cells. We propose that HP-associated methylation could stabilize trans-differentiation of marrow-derived stem cells and that an unstable methylation status is associated with a risk of gastric cancer. Pathobiologic behavior of experimental mouse gastric cancer is mild compared to invasive and metastatic human gastric cancer...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29055017/new-generation-nanomedicines-constructed-from-self-assembling-small-molecule-prodrugs-alleviate-cancer-drug-toxicity
#19
Hangxiang Wang, Zhongjie Lu, Lijiang Wang, Tingting Guo, Jiaping Wu, Jianqin Wan, Liqian Zhou, Hui Li, Zhen Li, Donghai Jiang, Penghong Song, Haiyang Xie, Lin Zhou, Xiao Xu, Shusen Zheng
The therapeutic index for chemotherapeutic drugs is determined in part by systemic toxicity, so strategies for dose intensification to improve efficacy must also address tolerability. In addressing this issue, we have investigated a novel combinatorial strategy of reconstructing a drug molecule and using sequential drug-induced nanoassembly to fabricate supramolecular nanomedicines (SNM). Using cabazitaxel (CTX) as a target agent, we established that individual synthetic prodrugs tethered with polyunsaturated fatty acids were capable of recapitulating self-assembly behavior independent of exogenous excipients...
October 20, 2017: Cancer Research
https://www.readbyqxmd.com/read/29054881/ablation-of-tfr1-in-purkinje-cells-inhibits-mglu1-trafficking-and-impairs-motor-coordination-but-not-autistic-like-behaviors
#20
Jia-Huan Zhou, Xin-Tai Wang, Liang Zhou, Lin Zhou, Fang-Xiao Xu, Li-Da Su, Hao Wang, Fan Jia, Fu-Qiang Xu, Gui-Quan Chen, Chris De Zeeuw, Ying Shen
Group 1 metabotropic glutamate receptors (mGlu1/5) are critical to synapse formation and participate in synaptic long-term potentiation (LTP) and long-term depression (LTD) in the brain. mGlu1/5 signaling alterations have been documented in cognitive impairment, neurodegenerative disorders, and psychiatric diseases, but underlying mechanisms for its modulation are not clear. Here, we report that transferrin receptor 1 (TFR1), a trans-membrane protein of clathrin complex, modulates the trafficking of mGlu1 in cerebellar Purkinje cells (PCs) from male mice...
October 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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