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https://www.readbyqxmd.com/read/28103599/evaluations-of-intravenous-administration-of-cd34-human-umbilical-cord-blood-cells-in-a-mouse-model-of-neonatal-hypoxic-ischemic-encephalopathy
#1
Makiko Ohshima, Akihiko Taguchi, Yoshiaki Sato, Yuko Ogawa, Satoshi Saito, Kenichi Yamahara, Masafumi Ihara, Mariko Harada-Shiba, Tomoaki Ikeda, Tomohiro Matsuyama, Masahiro Tsuji
Several cell therapies have been explored as novel therapeutic strategies for neonatal encephalopathy because the benefits of current treatments are limited. We previously reported that intravenous administration of human umbilical cord blood (hUCB) CD34+ cells (hematopoietic stem cells/endothelial progenitor cells) at 48 h after insult exerts therapeutic effects in neonatal mice with stroke, i.e., permanent middle cerebral artery occlusion. Although neonatal stroke and hypoxic-ischemic encephalopathy (HIE) are grouped under the term "neonatal encephalopathy," their pathogenesis differs...
January 20, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28103593/executive-dysfunction-and-behavioral-symptoms-are-associated-with-deficits-in-instrumental-activities-of-daily-living-in-frontotemporal-dementia
#2
Negar Moheb, Mario F Mendez, Sarah A Kremen, Edmond Teng
BACKGROUND: Deficits in instrumental activities of daily living (ADLs) may be more prominent in behavioral variant frontotemporal dementia (bvFTD) than in nonfluent/agrammatic variant primary progressive aphasia (nfvPPA) or semantic variant primary progressive aphasia (svPPA). It is uncertain whether frontotemporal dementia (FTD) subgroups exhibit different patterns and/or predictors of functional impairment. METHODS: We examined data from participants diagnosed with bvFTD (n = 607), svPPA (n = 132), and nfvPPA (n = 155) who were included in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set (UDS) and assessed with the Functional Activities Questionnaire (FAQ)...
January 20, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/28103587/magnetoresistance-and-hall-resistivity-of-semimetal-wte2-ultrathin-flakes
#3
Xin Luo, Chi Fang, Caihua Wan, Jialin Cai, Yong Liu, Xiufeng Han, Zhihong Lu, Rui Xiong, Zhongming Zeng
This article reports the characterization of WTe<sub>2</sub> ultrathin flakes devices with characterization of magnetoresistance and Hall resistivity. We found that ultrathin flakes of WTe<sub>2</sub> do not exhibit magnetoresistance saturation when subject to high fields, in a manner similar to their bulk characteristic. The linearity of Hall resistivity in our devices could confirm the compensation of electrons and holes. By relating experimental results to a classic two-band model, we demonstrate that the lower magnetoresistance values may be caused by decreased carrier mobility in our samples...
January 19, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28103567/predictive-control-of-networked-multiagent-systems-via-cloud-computing
#4
Guo-Ping Liu
This paper studies the design and analysis of networked multiagent predictive control systems via cloud computing. A cloud predictive control scheme for networked multiagent systems (NMASs) is proposed to achieve consensus and stability simultaneously and to compensate for network delays actively. The design of the cloud predictive controller for NMASs is detailed. The analysis of the cloud predictive control scheme gives the necessary and sufficient conditions of stability and consensus of closed-loop networked multiagent control systems...
January 18, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28103534/examining-the-link-between-cocaine-binging-and-individual-social-and-behavioral-factors-among-street-based-cocaine-users
#5
Élise Roy, Nelson Arruda, Didier Jutras-Aswad, Djamal Berbiche, Michel Perreault, Karine Bertrand, Magali Dufour, Julie Bruneau
AIMS: To estimate the prevalence of cocaine binging and examine associated factors, to characterize binge episodes and to study the relationship between cocaine binging and HIV and HCV risk behaviors among street-based cocaine users. METHODS: A prospective cohort study was conducted in Montréal, Canada. Interviewer-administered questionnaire were carried out at 3-month intervals. Cocaine binging was defined as using large quantities of cocaine, without stopping, over a limited period of time, until resources run out or until being physically incapable of consuming...
January 6, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28103496/toddlers-action-prediction-statistical-learning-of-continuous-action-sequences
#6
Claire D Monroy, Sarah A Gerson, Sabine Hunnius
The current eye-tracking study investigated whether toddlers use statistical information to make anticipatory eye movements while observing continuous action sequences. In two conditions, 19-month-old participants watched either a person performing an action sequence (Agent condition) or a self-propelled visual event sequence (Ghost condition). Both sequences featured a statistical structure in which certain action pairs occurred with deterministic transitional probabilities. Toddlers learned the transitional probabilities between the action steps of the deterministic action pairs and made predictive fixations to the location of the next action in the Agent condition but not in the Ghost condition...
January 16, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28103495/emotion-socialization-and-internalizing-behavior-problems-in-diverse-youth-a-bidirectional-relationship-across-childhood
#7
Naomi V Rodas, Denise A Chavira, Bruce L Baker
Mothers' and fathers' emotion socialization (ES) practices have been widely associated with child socioemotional outcomes. To extend this research, we examined the bidirectional relationship between parent ES practices (supportive and non-supportive parenting) and internalizing behavior problems in children of Anglo and Latino parents. Participants were 182 mothers and 162 fathers and their children with or without intellectual disability (ID). We compared the stability of mother and father ES practices across child ages 4-8...
January 16, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28103482/synaptic-plasticity-onto-dopamine-neurons-shapes-fear-learning
#8
Marco Pignatelli, George Kwabena Essien Umanah, Sissi Palma Ribeiro, Rong Chen, Senthilkumar Senthil Karuppagounder, Hau-Jie Yau, Stephen Eacker, Valina Lynn Dawson, Ted Murray Dawson, Antonello Bonci
Fear learning is a fundamental behavioral process that requires dopamine (DA) release. Experience-dependent synaptic plasticity occurs on DA neurons while an organism is engaged in aversive experiences. However, whether synaptic plasticity onto DA neurons is causally involved in aversion learning is unknown. Here, we show that a stress priming procedure enhances fear learning by engaging VTA synaptic plasticity. Moreover, we took advantage of the ability of the ATPase Thorase to regulate the internalization of AMPA receptors (AMPARs) in order to selectively manipulate glutamatergic synaptic plasticity on DA neurons...
January 18, 2017: Neuron
https://www.readbyqxmd.com/read/28103476/on-the-globality-of-motor-suppression-unexpected-events-and-their-influence-on-behavior-and-cognition
#9
REVIEW
Jan R Wessel, Adam R Aron
Unexpected events are part of everyday experience. They come in several varieties-action errors, unexpected action outcomes, and unexpected perceptual events-and they lead to motor slowing and cognitive distraction. While different varieties of unexpected events have been studied largely independently, and many different mechanisms are thought to explain their effects on action and cognition, we suggest a unifying theory. We propose that unexpected events recruit a fronto-basal-ganglia network for stopping...
January 18, 2017: Neuron
https://www.readbyqxmd.com/read/28103414/a-meta-analysis-of-the-association-between-appraisals-of-trauma-and-posttraumatic-stress-in-children-and-adolescents
#10
Ryan Mitchell, Kate Brennan, David Curran, Donncha Hanna, Kevin F W Dyer
Cognitive models of posttraumatic stress disorder (PTSD) place an emphasis on the role of negative appraisals of traumatic events. It is suggested that the way in which the event is appraised determines the extent to which posttraumatic stress symptoms will be experienced. Therefore, a strong relationship between trauma appraisals and symptoms of PTSD might be expected. However, this relationship is not as firmly established in the child and adolescent literature. A systematic literature review of this relationship returned 467 publications, of which 11 met full eligibility criteria...
January 19, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28103402/do-same-sex-mounts-function-as-dominance-assertion-in-male-golden-snub-nosed-monkeys-rhinopithecus-roxellana
#11
Pengzhen Huang, Xin He, Endi Zhang, Min Chen
It has been hypothesized that same-sex mounts can reflect the hierarchical relationship in a mounting dyad and it is widely deemed that mounting and being mounted are demonstrations of dominant and subordinate status, respectively. In this research, we aimed to test whether same-sex mounts function as dominance assertion in male golden snub-nosed monkeys (Rhinopithecus roxellana). We investigated this behavior in eight-individuals, captive all-male unit (AMU) in Shanghai wild animal park, China. Behavioral observations were conducted with a total of 1,855 mounts recorded from November, 2014 to June, 2015, during which the alpha male was replaced in the beginning of April...
January 19, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28103398/cognitive-behavioral-and-psycho-social-factors-associated-with-successful-and-maintained-quit-smoking-status-among-patients-who-received-smoking-cessation-intervention-with-nurses-counseling
#12
Chie Taniguchi, Hideo Tanaka, Hideo Saka, Isao Oze, Kazunobu Tachibana, Yasuhiro Nozaki, Yukio Suzuki, Hisataka Sakakibara
AIM: To identify cognitive, behavioral and psycho-social factors associated with successful and maintained quit smoking status after patients received smoking cessation intervention with nurses' counseling. BACKGROUND: Although nurses' intervention for smoking cessation is effective for patients, few studies have been conducted to identify cognitive, behavioral and psycho-social factors associated with the success of quitting smoking. DESIGN: Prospective cohort study METHODS: In a multi-institutional study between October 2008 - October 2014, we administered the Japanese smoking cessation therapy, which consists of smoking cessation intervention five times with nurses' counseling over 12 weeks...
January 19, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28103394/measuring-patient-engagement-which-health-care-engagement-behaviors-are-important-to-patients
#13
Huey-Ming Tzeng, James Marcus Pierson
AIM(S): This study identified patient health care engagement behaviors that are important to community-dwelling adult patients living in the southern region of the USA. BACKGROUND: Patient engagement has been identified as a key driver for containing health care costs, but the public and health care professionals lack a scientific understanding of patient engagement. A valid tool is needed for prompting patients to discuss health activities with their health care providers and to obtain support...
January 19, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28103371/condom-use-and-hiv-status-a-study-of-sex-workers-engaged-with-the-jamaican-aids-support-for-life-jasl
#14
H Budhwani, S Newton, K R Hearld, K Levermore
Objective: HIV prevention programs such as Jamaica AIDS Support for Life (JASL) work to lower the rate of HIV among marginalized groups. Thus, the objective of this study was to evaluate condom use and HIV status in JASL's Sex Worker (SW) population with the intent to identify behavioral differences between this self-selected group and the general SW population in Jamaica. We hypothesized that JASL's SW population would demonstrate higher condom use and a lower prevalence of HIV, potentially attributable to their prevention and education endeavours...
April 4, 2016: West Indian Medical Journal
https://www.readbyqxmd.com/read/28103315/multiple-acid-sensors-control-helicobacter-pylori-colonization-of-the-stomach
#15
Julie Y Huang, Emily Goers Sweeney, Karen Guillemin, Manuel R Amieva
Helicobacter pylori's ability to respond to environmental cues in the stomach is integral to its survival. By directly visualizing H. pylori swimming behavior when encountering a microscopic gradient consisting of the repellent acid and attractant urea, we found that H. pylori is able to simultaneously detect both signals, and its response depends on the magnitudes of the individual signals. By testing for the bacteria's response to a pure acid gradient, we discovered that the chemoreceptors TlpA and TlpD are each independent acid sensors...
January 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28103314/expression-of-a-mutant-sema3a-protein-with-diminished-signalling-capacity-does-not-alter-als-related-motor-decline-or-confer-changes-in-nmj-plasticity-after-botoxa-induced-paralysis-of-male-gastrocnemic-muscle
#16
Elizabeth B Moloney, Barbara Hobo, Fred De Winter, Joost Verhaagen
Terminal Schwann cells (TSCs) are specialized cells that envelop the motor nerve terminal, and play a role in the maintenance and regeneration of neuromuscular junctions (NMJs). The chemorepulsive protein semaphorin 3A (SEMA3A) is selectively up-regulated in TSCs on fast-fatigable muscle fibers following experimental denervation of the muscle (BotoxA-induced paralysis or crush injury to the sciatic nerve) or in the motor neuron disease amyotrophic lateral sclerosis (ALS). Re-expression of SEMA3A in this subset of TSCs is thought to play a role in the selective plasticity of nerve terminals as observed in ALS and following BotoxA-induced paralysis...
2017: PloS One
https://www.readbyqxmd.com/read/28103299/walking-through-apertures-in-individuals-with-stroke
#17
Daisuke Muroi, Yasuhiro Hiroi, Teruaki Koshiba, Yohei Suzuki, Masahiro Kawaki, Takahiro Higuchi
OBJECTIVE: Walking through a narrow aperture requires unique postural configurations, i.e., body rotation in the yaw dimension. Stroke individuals may have difficulty performing the body rotations due to motor paralysis on one side of their body. The present study was therefore designed to investigate how successfully such individuals walk through apertures and how they perform body rotation behavior. METHOD: Stroke fallers (n = 10), stroke non-fallers (n = 13), and healthy controls (n = 23) participated...
2017: PloS One
https://www.readbyqxmd.com/read/28103297/obesity-in-french-inmates-gender-differences-and-relationship-with-mood-eating-behavior-and-physical-activity
#18
Aude Lagarrigue, Soufiane Ajana, Lucile Capuron, Catherine Féart, Marie-Pierre Moisan
CONTEXT: Inmates, notably women, are at greater risk for obesity and metabolic complications than the general population according to several studies from high income countries. Data regarding French correctional institutions are lacking so far. To fill this gap, we have assessed in a sample from a French prison (33 females and 18 males) the gender-specific effect of incarceration on weight and body mass index (BMI) and examined their current metabolic status. Furthermore, to reveal the possible determinants of increased obesity, we analyzed emotional vulnerability, eating behavior and physical activity using self-reported questionnaires...
2017: PloS One
https://www.readbyqxmd.com/read/28103295/prevalence-and-trends-of-hiv-syphilis-and-hcv-in-migrant-and-resident-men-who-have-sex-with-men-in-shandong-china-results-from-a-serial-cross-sectional-study
#19
Jun Hu, Xu Gu, Xiaorun Tao, Yaosheng Qian, Giridhara R Babu, Guoyong Wang, Meizhen Liao, Larry Han, Dianmin Kang, Weiming Tang
BACKGROUND: Migrant men who have sex with men (MSM) have a higher predisposition for HIV transmission. We aimed to determine and compare the prevalence and trends of HIV, Syphilis, and HCV between migrant and resident MSM in Shandong, China. METHODS: A serial cross-sectional study was conducted in eight cities in Shandong, China from 2010 to 2014. The surveys collected information on demographics, HIV-related knowledge, and HIV-related behaviors including the serologic status of HIV, syphilis, and HCV...
2017: PloS One
https://www.readbyqxmd.com/read/28103292/muscle-reactive-oxygen-species-ros-contribute-to-post-incisional-guarding-via-the-trpa1-receptor
#20
Daisuke Sugiyama, Sinyoung Kang, Timothy J Brennan
BACKGROUND: Deep tissues and their afferents have unique responses to various stimuli and respond to injury distinctively. However, the types of receptors and endogenous ligands that have a key role in pain after deep tissue incision are unknown. TRPA1 has been shown to mediate pain-related responses in inflammation- and nerve injury-induced pain models. We hypothesized that TRPA1 has an important role in pain behaviors after deep tissue incision. METHODS: The effect of various doses of intraperitoneal (i...
2017: PloS One
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