keyword
MENU ▼
Read by QxMD icon Read
search

Net clinical benefit

keyword
https://www.readbyqxmd.com/read/29678939/the-use-of-mri-detected-synovitis-to-determine-the-number-of-involved-joints-for-the-2010-acr-eular-classification-criteria-for-rheumatoid-arthritis-is-it-of-additional-benefit
#1
Aleid C Boer, Debbie M Boeters, Annette H M van der Helm-van Mil
OBJECTIVE: To assess the value of MRI-detected synovitis to determine the number of involved joints on the performance of the 2010-ACR/EULAR classification criteria for rheumatoid arthritis (RA). METHODS: 277 patients with a clinical suspicion of RA consecutively included in the Leiden Early Arthritis Clinic (EAC)-cohort underwent 1.5T MRI of MCP-, wrist- and MTP-joints. Test characteristics of the 2010-criteria were calculated when the number of involved joints was determined with and without including MRI-detected synovitis...
April 20, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29676063/development-and-internal-validation-of-a-side-specific-multiparametric-mri-based-nomogram-for-the-prediction-of-extracapsular-extension-of-prostate-cancer
#2
Alberto Martini, Akriti Gupta, Sara C Lewis, Shivaram Cumarasamy, Kenneth G Haines, Alberto Briganti, Francesco Montorsi, Ash K Tewari
OBJECTIVES: To develop a nomogram for predicting side-specific extracapsular extension (ECE) for planning nerve sparing radical prostatectomy (NSRP). MATERIALS AND METHODS: We retrospectively analyzed data from 561 patients who underwent robot-assisted radical prostatectomy between February 2014 and October 2015. To develop a side-specific predictive model, we considered the prostatic lobes separately. Four variables were included: PSA, highest ipsilateral biopsy Gleason grade, highest ipsilateral percentage core involvement and ECE on multiparametric MRI (mpMRI)...
April 19, 2018: BJU International
https://www.readbyqxmd.com/read/29675259/successful-neoadjuvant-peptide-receptor-radionuclide-therapy-for-an-inoperable-pancreatic-neuroendocrine-tumour
#3
Tiago Nunes da Silva, M L F van Velthuysen, Casper H J van Eijck, Jaap J Teunissen, J Hofland, Wouter W de Herder
Non-functional pancreatic neuroendocrine tumours (NETs) can present with advanced local or distant (metastatic) disease limiting the possibility of surgical cure. Several treatment options have been used in experimental neoadjuvant settings to improve the outcomes in such cases. Peptide receptor radionuclide therapy (PPRT) using beta emitting radiolabelled somatostatin analogues has been used in progressive pancreatic NETs. We report a 55-year-old female patient with a 12.8 cm pancreatic NET with significant local stomach and superior mesenteric vein compression and liver metastases...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29673293/systemic-thrombolytic-therapy-for-massive-and-submassive-pulmonary-embolism
#4
Lauren A Igneri, John M Hammer
OBJECTIVE: To critically evaluate the published literature assessing the safety and efficacy of thrombolytic therapy for massive and submassive pulmonary embolism (PE). METHODS: A search of human trials in the English-language (September 2017) was conducted through the MEDLINE database using the following terms: PE, tissue plasminogen activator, tenecteplase, and alteplase. 67 unique articles were identified, of which 24 clinical trials discussing clinical outcomes related to administration of either intravenous tenecteplase or alteplase were included...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29672327/the-affordable-care-act-decreased-the-proportion-of-uninsured-patients-in-a-safety-net-orthopaedic-clinic
#5
Joseph A Gil, Avi D Goodman, Justin Kleiner, Robin N Kamal, Laurence C Baker, Edward Akelman
BACKGROUND: The Patient Protection and Affordable Care Act (ACA) was approved in 2010, substantially altering the economics of providing and receiving healthcare services in the United States. One of the primary goals of this legislation was to expand insurance coverage for under- and uninsured residents. Our objective was to examine the effect of the ACA on the insurance status of patients at a safety net clinic. Our institution houses a safety net clinic that provides the dominant majority of orthopaedic care for uninsured patients in our state...
May 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29665617/transradial-versus-transfemoral-approach-for-diagnostic-coronary-angiography-and-percutaneous-coronary-intervention-in-people-with-coronary-artery-disease
#6
REVIEW
Ahmed A Kolkailah, Rabah S Alreshq, Ahmed M Muhammed, Mohamed E Zahran, Marwah Anas El-Wegoud, Ashraf F Nabhan
BACKGROUND: Cardiovascular disease (CVD) is the major cause of mortality worldwide. Coronary artery disease (CAD) contributes to half of mortalities caused by CVD. The mainstay of management of CAD is medical therapy and revascularisation. Revascularisation can be achieved via coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). Peripheral arteries, such as the femoral or radial artery, provide the access to the coronary arteries to perform diagnostic or therapeutic (or both) procedures...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29661752/a-novel-information-retrieval-tool-to-find-hospital-care-team-members-development-and-usability-study
#7
Kyle Morawski, Craig Monsen, Sukhjit Takhar, Adam Landman
BACKGROUND: Hospital communication among members of a patient's care team is a central part of clinical workflow and consumes a large amount of a health care provider's time. Oftentimes the complexity of hospital care leads to difficulty in finding the appropriate contact, which can lead to inefficiencies and frustration. Squire is a Web-based information retrieval app created to improve the speed and efficiency in reaching the appropriate team member during the care of a hospitalized patient...
April 16, 2018: JMIR Human Factors
https://www.readbyqxmd.com/read/29661283/2-octylcyanoacrylate-for-the-prevention-of-anastomotic-leak
#8
Anthony B Costales, Deepa Patil, Anny Mulya, John P Kirwan, Chad M Michener
BACKGROUND: Anastomotic leak after colorectal surgery is a significant cause of morbidity and mortality. The aim of this study was to evaluate the impact of a reinforced colo-colonic anastomosis with tissue adhesive, 2-octylcyanoacrylate (2-OCA), on the integrity of anastomotic healing as measured by anastomotic bursting pressure. METHODS: Sixty-eight female Sprague-Dawley rats underwent a rectosigmoid colon transection and a sutured end-to-end anastomosis followed by randomization to receive no further intervention or reinforcement with the tissue adhesive, 2-OCA...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29659067/computer-aided-diagnosis-of-prostate-cancer-using-a-deep-convolutional-neural-network-from-multiparametric-mri
#9
Yang Song, Yu-Dong Zhang, Xu Yan, Hui Liu, Minxiong Zhou, Bingwen Hu, Guang Yang
BACKGROUND: Deep learning is the most promising methodology for automatic computer-aided diagnosis of prostate cancer (PCa) with multiparametric MRI (mp-MRI). PURPOSE: To develop an automatic approach based on deep convolutional neural network (DCNN) to classify PCa and noncancerous tissues (NC) with mp-MRI. STUDY TYPE: Retrospective. SUBJECTS: In all, 195 patients with localized PCa were collected from a PROSTATEx database...
April 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29658538/-effectiveness-of-oral-nutritional-supplements-to-prevent-hospital-malnutrition-overview-of-systematic-reviews
#10
Luca Giuseppe Re, Maura Lusignani
. Effectiveness of oral nutritional supplements to prevent hospital malnutrition. Overview of systematic reviews. INTRODUCTION: Although oral nutritional supplements (ONSs) are among most popular interventions to prevent a condition of hospital malnutrition, their real benefits need to be clarified. AIM: To evaluate in adults the effectiveness of ONSs to prevent hospital malnutrition. METHODS: Papers retrieval by querying biomedical databases The Cochrane Library, Medline, Embase, CINAHL...
January 2018: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/29650121/prediction-of-abnormal-myocardial-relaxation-from-signal-processed-surface-ecg
#11
Partho P Sengupta, Hemant Kulkarni, Jagat Narula
BACKGROUND: Myocardial relaxation is impaired in almost all cases with left ventricular diastolic dysfunction (LVDD) and is a strong predictor of cardiovascular and all-cause mortality. OBJECTIVES: This study investigated the feasibility of signal-processed surface electrocardiography (spECG) as a diagnostic tool for predicting the presence of abnormal cardiac muscle relaxation. METHODS: A total of 188 outpatients referred for coronary computed tomography (CT) angiography underwent an echocardiogram for assessment of LVDD...
April 17, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29644412/patent-foramen-ovale-closure-versus-medical-therapy-for-prevention-of-recurrent-cryptogenic-embolism-updated-meta-analysis-of-randomized-clinical-trials
#12
Brunilda Alushi, Alexander Lauten, Salvatore Cassese, Roisin Colleran, Stefanie Schüpke, Himanshu Rai, Heribert Schunkert, Bernhard Meier, Ulf Landmesser, Adnan Kastrati
BACKGROUND: We performed an updated meta-analysis of all randomized-controlled trials (RCTs) comparing patent foramen ovale (PFO) closure with medical therapy for prevention of recurrent ischemic stroke. METHODS AND RESULTS: We searched Medline, EMBASE, and Cochrane databases, and proceedings of international meetings for RCTs of patients with cryptogenic stroke and PFO comparing percutaneous PFO closure versus medical therapy for prevention of recurrent ischemic stroke...
April 11, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29644229/cantos-a-breakthrough-that-proves-the-inflammatory-hypothesis-of-atherosclerosis
#13
Mohamed Hassan
Atherosclerosis is no longer considered solely a disorder of subintimal deposition of modified low-density lipoprotein particles in the arterial wall. Rather, it is known to be a chronic inflammatory disorder. No evidence has shown that reducing vascular inflammation in the absence of concomitant lowering of lipoproteins levels reduces the rates of adverse cardiovascular (CV) events. Canakinumab, a fully human monoclonal antibody that neutralizes interleukin (IL)-1β, significantly reduced the rate of recurrent CV events in patients with prior myocardial infarction in the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS)...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29623234/the-positive-benefits-of-negative-movement-patterns-following-total-knee-arthroplasty
#14
Jesse C Christensen, K Bo Foreman, Paul C LaStayo
Introduction: Eccentric (negative) resistance exercise of the legs using specialized machines has been reported to be useful and often superior to standard exercise following total knee arthroplasty (TKA). Movements that utilize body mass and gravity as a mode of eccentric resistance exercise in a more pragmatic rehabilitation paradigm may also be useful in reversing chronic muscle impairments observed years following surgery. This study explores whether an eccentrically biased, body mass resistance exercise induces greater magnitude of sagittal plane extensor angular impulse of the support torque and individual net joint torque contributions during both squatting and lunging movement patterns 6 weeks following TKA...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29621763/predictive-value-of-four-dimensional-strain-echocardiography-for-adverse-cardiovascular-outcomes-in-st-elevation-myocardial-infarction-patients-treated-with-primary-percutaneous-coronary-intervention
#15
Wei Cai, Yan Dong, Lu Tian, Chun-Xia Cao, Xiu-Long Niu, Xin-Lin Liu, Jun-Xiang Liu, Wen-Jie Ji, Zhuoli Zhang, Xin Zhou, Yu-Ming Li
OBJECTIVES: To investigate the predictive value of four-dimensional (4D) strain echocardiography for major adverse cardiovascular events (MACE) in ST-elevation acute myocardial infarction (STEMI) patients. METHODS: Consecutive STEMI patients who underwent successful primary coronary interven tion (PCI) were enrolled and followed, with 2D and 4D strain echocardiography performed within 1 week after PCI. RESULTS: Twenty-six first MACE were recorded in 81 patients who finished a ∼3...
April 5, 2018: Cardiology
https://www.readbyqxmd.com/read/29618963/value-of-investment-as-a-key-driver-for-prioritization-and-implementation-of-healthcare-software
#16
Seth A Bata, Terry Richardson
Health systems across the nation are recovering from massive financial and resource investments in electronic health record applications. In the midst of these recovery efforts, implementations of new care models, including accountable care organizations and population health initiatives, are underway. The shift from fee-for-service to fee-for-outcomes and fee-for-value payment models calls for care providers to work in new ways. It also changes how physicians are compensated and reimbursed. These changes necessitate that healthcare systems further invest in information technology solutions...
2018: Perspectives in Health Information Management
https://www.readbyqxmd.com/read/29614652/single-subject-classification-of-alzheimer-s-disease-and-behavioral-variant-frontotemporal-dementia-using-anatomical-diffusion-tensor-and-resting-state-functional-magnetic-resonance-imaging
#17
Mark J R J Bouts, Christiane Möller, Anne Hafkemeijer, John C van Swieten, Elise Dopper, Wiesje M van der Flier, Hugo Vrenken, Alle Meije Wink, Yolande A L Pijnenburg, Philip Scheltens, Frederik Barkhof, Tijn M Schouten, Frank de Vos, Rogier A Feis, Jeroen van der Grond, Mark de Rooij, Serge A R B Rombouts
BACKGROUND/OBJECTIVE: Overlapping clinical symptoms often complicate differential diagnosis between patients with Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD). Magnetic resonance imaging (MRI) reveals disease specific structural and functional differences that aid in differentiating AD from bvFTD patients. However, the benefit of combining structural and functional connectivity measures to-on a subject-basis-differentiate these dementia-types is not yet known...
January 24, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29614509/modest-impact-of-serial-measurements-of-acute-kidney-injury-biomarkers-in-an-adult-intensive-care-unit
#18
Rei Isshiki, Toshifumi Asada, Maki Sumida, Yoshifumi Hamasaki, Masaomi Nangaku, Eisei Noiri, Kent Doi
BACKGROUND/AIMS: Acute kidney injury (AKI) biomarkers have been developed with the aim of being able to detect kidney damage earlier than the detection process based on serum creatinine levels. However, single time-point measurements appear to furnish insufficient information for detecting and predicting AKI in intensive care unit patients who are frequently affected by multiple and transient/persistent renal insults. We evaluated whether serial measurements enable the prediction of AKI outcomes in such patients...
April 3, 2018: Nephron
https://www.readbyqxmd.com/read/29610124/is-there-really-a-benefit-to-net-clinical-benefit-in-testing-antithrombotics
#19
Philippe Gabriel Steg, Deepak L Bhatt
No abstract text is available yet for this article.
April 3, 2018: Circulation
https://www.readbyqxmd.com/read/29609751/optimizing-statins-and-ezetimibe-in-guideline-focused-management
#20
REVIEW
Aref A Bin Abdulhak, Jennifer G Robinson
Statins are essential medications in the management of patients with clinical atherosclerotic cardiovascular disease, and have been supported by numerous clinical trials. Emerging evidence suggests that adding ezetimibe to statin therapy is associated with a net benefit and improved hard clinical outcomes, particularly in patients with significantly elevated atherosclerotic cardiovascular disease risk and elevated low-density lipoprotein cholesterol levels.
May 2018: Cardiology Clinics
keyword
keyword
62198
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"