Maeve Louise Farrell, Alexandra Chueiri, Mark Maguire, Aneta Kovářová, Georgios Miliotis, Louise O'Connor, Francesca McDonagh, Sinead Duane, Martin Cormican, Genevieve Devane, Alma Tuohy, Niall DeLappe, Florence De Bock, Liam P Burke, Dearbháile Morris
The increasing prevalence of extended-spectrum beta-lactamase (ESBL) producing Enterobacterales (ESBL-PE) and carbapenemase-producing Enterobacterales (CPE) is a major public health concern worldwide. Despite the associated risk of infection from gut colonisation with a resistant Enterobacterales, the incidence and duration of carriage in healthy individuals is poorly studied. This "persistence study" is the first in Ireland to assess the longitudinal carriage of ESBL-PE and CPE in healthy individuals. A cohort of 45 participants, 22 of whom were colonised with ESBL-PE, was recruited from a recently completed point prevalence study that investigated colonisation in recreational water users (WU) versus controls...
September 15, 2023: Science of the Total Environment