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https://www.readbyqxmd.com/read/28095119/fecal-carriage-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-strains-is-associated-with-worse-outcome-in-patients-hospitalized-in-the-pediatric-oncology-unit-of-beni-messous-hospital-in-algiers-algeria
#1
Chafiaa Medboua-Benbalagh, Abdelaziz Touati, Rachida Kermas, Alima Gharout-Sait, Lucien Brasme, Halima Mezhoud, Djamila Touati, Thomas Guillard, Christophe de Champs
OBJECTIVES: The current study aimed to investigate extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) fecal carriage in children with different cancers admitted in the pediatric oncology unit of Beni-Messous Hospital (Algiers, Algeria). MATERIALS AND METHODS: Rectal swabs from children with cancer were sampled from February 2012 to May 2013 within 48 hours following their admission. After species identification and detection of ESBL production by double-disk synergy test (DD test), antibiotic susceptibility was determined by the standard disk diffusion method...
January 17, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28093116/captive-and-free-living-urban-pigeons-columba-livia-from-brazil-as-carriers-of-multidrug-resistant-pathogenic-escherichia-coli
#2
Clarissa A Borges, Renato P Maluta, Lívia G Beraldo, Marita V Cardozo, Elisabete A L Guastalli, Subhashinie Kariyawasam, Chitrita DebRoy, Fernando A Ávila
Thirty Escherichia coli isolates from captive and free-living pigeons in Brazil were characterised. Virulence-associated genes identified in pigeons included those which occur relatively frequently in avian pathogenic E. coli (APEC) from commercial poultry worldwide. Eleven of 30 E. coli isolates from pigeons, belonging mainly to B1 and B2 phylogenetic groups, had high or intermediate pathogenicity for 1-day-old chicks. The frequency of multi-drug resistant (MDR) E. coli in captive pigeons was relatively high and included one isolate positive for the extended-spectrum β-lactamase (ESBL) gene blaCTX-M-8...
January 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28049493/presence-of-foodborne-pathogens-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-and-methicillin-resistant-staphylococcus-aureus-in-slaughtered-reindeer-in-northern-finland-and-norway
#3
Sauli Laaksonen, Antti Oksanen, Jérôme Julmi, Claudio Zweifel, Maria Fredriksson-Ahomaa, Roger Stephan
BACKGROUND: Various food-producing animals were recognized in recent years as healthy carriers of bacterial pathogens causing human illness. In northern Fennoscandia, the husbandry of semi-domesticated reindeer (Rangifer tarandus tarandus) is a traditional livelihood and meat is the main product. This study determined the presence of selected foodborne pathogens, methicillin-resistant Staphylococcus aureus (MRSA), and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in healthy semi-domesticated reindeer at slaughter in northern Finland and Norway...
January 3, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27965302/proton-pump-inhibitor-use-is-associated-with-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-rectal-carriage-at-hospital-admission-a-cross-sectional-study
#4
Pepijn Huizinga, Marjolein Kluytmans- van den Bergh, Miranda van Rijen, Ina Willemsen, Nils van 't Veer, Jan Kluytmans
In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).
February 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27942042/faecal-carriage-of-gram-negative-multidrug-resistant-bacteria-among-patients-hospitalized-in-two-centres-in-ulaanbaatar-mongolia
#5
Bayaraa Baljin, Ganbaatar Baldan, Battogtokh Chimeddorj, Khosbayar Tulgaa, Batbaatar Gunchin, Tsogtsaikhan Sandag, Klaus Pfeffer, Colin R MacKenzie, Andreas F Wendel
Gram-negative multidrug-resistant organisms (GN-MDRO) producing β-lactamases (ESBL, plasmid-mediated AmpC β-lactamases and carbapenemases) are increasingly reported throughout Asia. The aim of this surveillance study was to determine the rate of bacterial colonization in patients from two hospitals in the Mongolian capital Ulaanbaatar. Rectal swabs were obtained from patients referred to the National Traumatology and Orthopaedics Research Centre (NTORC) or the Burn Treatment Centre (BTC) between July and September 2014, on admission and again after 14 days...
2016: PloS One
https://www.readbyqxmd.com/read/27902381/detection-of-escherichia-coli-st131-complex-st705-and-klebsiella-pneumoniae-st15-among-fecal-carriage-of-extended-spectrum-betalactamase-and-carbapenemase-producing-enterobacteriaceae
#6
Esther Rios, Maria Carmen López, Iciar Rodríguez-Avial, Esther Culebras, Juan Jose Picazo
The objective of the present study was to evaluate the prevalence of intestinal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and carbapenemases-producing Enterobacteriaceae (CPE) in non-selected hospitalized and non-hospitalized patients from the same geographic area of Madrid. Among the 501 patients enrolled, 43 (8.6%) carried ESBL-E and 8 (1.6%) patients exhibited CPE. The main intestinal colonizer among ESBL-E was CTX-M-producing Escherichia coli isolates in both settings (community and hospital)...
November 28, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27889252/peripartum-maternal-transmission-of-extended-spectrum-%C3%AE-lactamase-organism-to-newborn-infants
#7
Avi Peretz, Alina Skuratovsky, Efrat Khabra, Amos Adler, Nina Pastukh, Shay Barak, Yuri Perlitz, Moshe Ben-Ami, Amir Kushnir
The aim of this study was to determine whether the route of extended-spectrum β-lactamase (ESBL) transmission to hospitalized newborns was from their mothers during delivery. Neonatal intensive care unit (NICU) hospitalized newborns were sampled for ESBL presence by stool cultures on the first and fourth days of life. Mothers of ESBL-positive newborns were sampled for possible correlation detection. Bacteria isolates were molecularly identified and susceptibility tests for antibiotic agents were performed...
February 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27812159/enterobacteriaceae-isolated-from-the-river-danube-antibiotic-resistances-with-a-focus-on-the-presence-of-esbl-and-carbapenemases
#8
Clemens Kittinger, Michaela Lipp, Bettina Folli, Alexander Kirschner, Rita Baumert, Herbert Galler, Andrea J Grisold, Josefa Luxner, Melanie Weissenbacher, Andreas H Farnleitner, Gernot Zarfel
In a clinical setting it seems to be normal these days that a relevant proportion or even the majority of different bacterial species has already one or more acquired antibiotic resistances. Unfortunately, the overuse of antibiotics for livestock breeding and medicine has also altered the wild-type resistance profiles of many bacterial species in different environmental settings. As a matter of fact, getting in contact with resistant bacteria is no longer restricted to hospitals. Beside food and food production, the aquatic environment might also play an important role as reservoir and carrier...
2016: PloS One
https://www.readbyqxmd.com/read/27806830/acquisition-of-extended-spectrum-%C3%AE-lactamases-during-travel-abroad-a-qualitative-study-among-swedish-travellers-examining-their-knowledge-risk-assessment-and-behaviour
#9
Susanne Wiklund, Ingegerd Fagerberg, Åke Örtqvist, Kristina Broliden, Ann Tammelin
BACKGROUND: Travel to foreign countries involves the risk of becoming a carrier of antibiotic-resistant bacteria, especially when the destination is a country with a high prevalence of this type of bacteria. AIM AND METHODS: The aim of this study was to learn about the knowledge of antibiotic resistance, and the behaviour and risk-taking among travellers, who had become carriers of extended spectrum beta-lactamases (ESBL)-producing bacteria during travel to a high-prevalence country...
2016: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/27798205/community-carriage-of-esbl-producing-escherichia-coli-is-associated-with-strains-of-low-pathogenicity-a-swedish-nationwide-study
#10
Sofia Ny, Sonja Löfmark, Stefan Börjesson, Stina Englund, Maj Ringman, Jakob Bergström, Pontus Nauclér, Christian G Giske, Sara Byfors
OBJECTIVES: Community carriage of ESBL-producing Escherichia coli (EPE) is common worldwide and there is a need to understand the connection between carriage and infection. We compared the molecular characteristics of EPE among Swedish community carriers with those of EPE causing invasive infections. METHODS: We collected 2134 faecal samples from randomly selected Swedish inhabitants and examined them for the presence of EPE. All participating volunteers answered a questionnaire about putative risk factors for EPE carriage...
October 24, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27795466/the-characteristics-of-extended-spectrum-%C3%AE-lactamases-producing-escherichia-coli-in-hospital-faecal-carriage-in-beijing-tongren-hospital
#11
Maoye Xu, Yanyan Fan, Mei Wang, Xinxin Lu
We aimed to investigate the prevalence of extended-spectrum β-lactamases (ESBL)-producing Escherichia coli (E. coli) in Beijing Tongren hospital and find the relationship between colonization and infection. The clinical data of 650 inpatients included between March 2012 and July 2012 were retrospectively reviewed. The prevalence of ESBL-producing E. coli among inpatients was 25.7% (167/650), with the highest of 50.0% in rheumatology ward and lowest of 10.0% in intensive care unit. Hospital stay more than 2 years, usage of antibiotics less than 3 months, and use of glucocorticoids or immunosuppressive were found to be significantly associated with ESBL carriage (P < 0...
October 31, 2016: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27751772/import-and-spread-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-by-international-travellers-combat-study-a-prospective-multicentre-cohort-study
#12
Maris S Arcilla, Jarne M van Hattem, Manon R Haverkate, Martin C J Bootsma, Perry J J van Genderen, Abraham Goorhuis, Martin P Grobusch, Astrid M Oude Lashof, Nicky Molhoek, Constance Schultsz, Ellen E Stobberingh, Henri A Verbrugh, Menno D de Jong, Damian C Melles, John Penders
BACKGROUND: International travel contributes to the dissemination of antimicrobial resistance. We investigated the acquisition of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) during international travel, with a focus on predictive factors for acquisition, duration of colonisation, and probability of onward transmission. METHODS: Within the prospective, multicentre COMBAT study, 2001 Dutch travellers and 215 non-travelling household members were enrolled...
January 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27694727/multidrug-resistant-esbl-producing-enterobacteriaceae-and-associated-risk-factors-in-community-infants-in-lebanon
#13
Soumaya Moustafa Hijazi, Mohamad Anwar Fawzi, Faten Moustafa Ali, Khaled Hussein Abd El Galil
INTRODUCTION: Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) infections are a growing threat to children, and the treatment of these infections becomes more and more challenging. A huge reservoir for ESBLs in the community is the fecal flora of children. This study investigates the rectal colonization, associated risk factors, antimicrobial susceptibility, and molecular characterization of ESBL-PE in Lebanese community infants. METHODOLOGY: A total of 117 rectal swabs were taken from healthy infants between 1 and 12 months of age...
September 30, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/27650029/-the-threat-of-antibiotic-resistance-to-nursing-homes
#14
M J M Bonten
Antibiotic resistance is considered a major threat to healthcare. The Dutch government recently announced additional measures to contain this threat, one of these being the creation of regional care networks dedicated to control antibiotic resistance. Among the anticipated activities of these networks is quantifying the prevalence of antibiotic resistance in nursing homes, through regular point-prevalence surveillance studies. There is a broadly felt belief that nursing homes might be a 'mer à boire' of antibiotic resistance...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27608837/faecal-carriage-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-and-shiga-toxin-producing-escherichia-coli-in-asymptomatic-nursery-children-in-lower-saxony-germany-2014
#15
M Harries, J Dreesman, S Rettenbacher-Riefler, E Mertens
Children may be at higher risk for carriage of antimicrobial-resistant bacteria because of higher usage of antimicrobials. They also have higher rates of Shiga toxin-producing Escherichia coli (STEC) infections than other population groups. Some infections, particularly in children, are asymptomatic, but still lead to the excretion of large numbers of bacteria and viruses that may cause clinical disease in other individuals. That is one reason why, in Lower Saxony as in other German federal states - asymptomatic carriers of STEC are excluded from nurseries and schools until three consecutive stool samples test negative in order to prevent secondary cases...
September 9, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27600033/prospective-cohort-study-of-the-relative-abundance-of-extended-spectrum-beta-lactamase-producing-escherichia-coli-in-the-gut-of-patients-admitted-to-hospitals
#16
Victoire de Lastours, Dorothée Chopin, Hervé Jacquier, Camille d'Humières, Charles Burdet, Françoise Chau, Erick Denamur, Bruno Fantin
A total of 458 patients were prospectively included at hospital admission and screened for extended-spectrum-beta-lactamase-producing (ESBL) Escherichia coli carriage in 2007 and in 2010 to 2012. A 4-fold increase in ESBL carriage (3% to 12%), a 5-fold increase in numbers of community patients among ESBL carriers, and a higher number of multiple ESBL strains was found in the 2010 to 2012 period. ESBL E. coli represented the dominant E. coli strain (relative abundance, >50%) in 10/32 (31%) of ESBL carriers...
November 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27574974/high-gastrointestinal-colonization-rate-with-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-in-hospitalized-patients-emergence-of-carbapenemase-producing-k-pneumoniae-in-ethiopia
#17
Kassu Desta, Yimtubezinash Woldeamanuel, Aklilu Azazh, Halima Mohammod, Dawit Desalegn, Damte Shimelis, Dereje Gulilat, Biruk Lamisso, Eyasu Makonnen, Alemayehu Worku, Kerstin Mannerqvist, Johan Struwe, Olov Aspevall, Eleni Aklillu
We investigated the gastrointestinal colonization rate and antibiotic resistance patterns of Extended-Spectrum Beta-Lactamase (ESBL)- producing Escherichia coli and Klebsiella pneumoniae in hospitalized patients admitted at Ethiopia's largest tertiary hospital. Fecal samples/swabs from 267 patients were cultured on chrome agar. ESBL. Bacterial species identification, verification of ESBL production and antibiotic susceptibility testing were done using Vitek 2 system (bioMérieux, France). Phenotype characterization of ESBL-E...
2016: PloS One
https://www.readbyqxmd.com/read/27499852/carriage-of-multidrug-resistant-organisms-in-a-tertiary-university-hospital-in-albania-a-point-prevalence-survey
#18
Falzon A Parascandalo, P Zarb, E Tartari, D Lacej, S Bitincka, O Manastirliu, D Nika, M A Borg
BACKGROUND: Antimicrobial resistance has been recognised as a serious global Public Health problem. Prevalence of Multiple-Drug-Resistant (MDR) organism carriage in Albania is largely unknown since no national surveillance system is in place and few publications are accessible in the literature. METHODS: A 1-day point-prevalence-survey (PPS) screening for nasal methicillin-resistant Staphylococcus aureus (MRSA) and rectal MDR Gram-negative carriage was carried out at the high-dependency wards in the country's only tertiary care hospital, in Tirana...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27400864/high-prevalence-of-extended-spectrum-%C3%A3-lactamase-producing-enterobacteriaceae-among-clinical-isolates-in-burkina-faso
#19
Abdoul-Salam Ouedraogo, Mahamadou Sanou, Aimée Kissou, Soufiane Sanou, Hermann Solaré, Firmin Kaboré, Armel Poda, Salim Aberkane, Nicolas Bouzinbi, Idrissa Sano, Boubacar Nacro, Lassana Sangaré, Christian Carrière, Dominique Decré, Rasmata Ouégraogo, Hélène Jean-Pierre, Sylvain Godreuil
BACKGROUND: Nothing is known about the epidemiology and resistance mechanisms of extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) in Burkina Faso. The objective of this study was to determine ESBL-PE prevalence and to characterize ESBL genes in Burkina Faso. METHODS: During 2 months (June-July 2014), 1602 clinical samples were sent for bacteriologic investigations to the microbiology laboratories of the tree main hospitals of Burkina Faso. Isolates were identified by mass spectrometry using a matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) BioTyper...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27330043/evidence-of-household-transfer-of-esbl-pampc-producing-enterobacteriaceae-between-humans-and-dogs-a-pilot-study
#20
Oskar Ljungquist, Ditte Ljungquist, Mattias Myrenås, Cecilia Rydén, Maria Finn, Björn Bengtsson
BACKGROUND: Extended-spectrum cephalosporin-resistant Enterobacteriaceae (ESCRE) are an increasing healthcare problem in both human and veterinary medicine. The spread of ESCRE is complex with multiple reservoirs and different transmission routes. The aim of this study was to investigate if ESCRE carriage in dogs is more prevalent in households with a known human carrier, compared to households where humans are known to be negative for ESCRE. Identical ESCRE strains in humans and dogs of the same household would suggest a possible spread between humans and dogs...
2016: Infection Ecology & Epidemiology
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