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https://www.readbyqxmd.com/read/28217414/dance-balance-and-core-muscle-performance-measures-are-improved-following-a-9-week-core-stabilization-training-program-among-competitive-collegiate-dancers
#1
Todd Watson, Jessica Graning, Sue McPherson, Elizabeth Carter, Joshuah Edwards, Isaac Melcher, Taylor Burgess
BACKGROUND: Dance performance requires not only lower extremity muscle strength and endurance, but also sufficient core stabilization during dynamic dance movements. While previous studies have identified a link between core muscle performance and lower extremity injury risk, what has not been determined is if an extended core stabilization training program will improve specific measures of dance performance. HYPOTHESIS/PURPOSE: This study examined the impact of a nine-week core stabilization program on indices of dance performance, balance measures, and core muscle performance in competitive collegiate dancers...
February 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28216321/effects-of-dmso-on-a-rabbit-ear-hypertrophic-scar-model-a-controlled-randomized-experimental-study
#2
Elif Sari, Bulent Bakar, Gungor Cagdas Dincel, Fatma Azize Budak Yildiran
Dimethyl sulfoxide (DMSO) is an anti-inflammatory, antibacterial, analgesic drug widely used to treat several diseases as reported in the literature. It has a detractive effect on collagen deposition in the abnormal tissue. This study aimed to investigate the possible therapeutic effects of DMSO on hypertrophic scar formation in rabbits. Twenty-four New Zealand male albino rabbits were randomly divided into four groups: control, sham, DMSO, and TRA (triamcinolone acetonide). Except the control group, punch biopsy defects were created on each animal's right ear...
January 23, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28216229/trans-ulnar-catheterization-and-coronary-interventions-from-technique-to-outcomes
#3
REVIEW
Sudhakar Sattur, Maninder Singh, Edo Kaluski
The ulnar artery is similar in size to the radial artery, however it is more difficult to palpate and access. For those physicians who mastered trans-ulnar access (TUA) this access site serves as an alternative to trans radial access (TRA) when the radial artery access is rendered suboptimal (by palpation, ultrasound examination or previous procedural records) or when encountering TRA difficulties or failure. The manuscript describes the anatomy, suggested technique, procedural success and complications associated with TUA...
February 1, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28215675/basic-fibroblast-growth-factor-is-critical-to-reprogramming-buffalo-bubalus-bubalis-primordial-germ-cells-into-embryonic-germ-stem-cell-like-cells
#4
Caizhu Wang, Yanfei Deng, Feng Chen, Peng Zhu, Jingwei Wei, Chan Luo, Fenghua Lu, Sufang Yang, Deshun Shi
Primordial germ cells (PGCs) are destined to form gametes in vivo, and they can be reprogrammed into pluripotent embryonic germ (EG) cells in vitro. Buffalo PGC have been reported to be reprogrammed into EG-like cells, but the identities of the major signaling pathways and culture media involved in this derivation remain unclear. Here, the effects of basic fibroblast growth factor (bFGF) and downstream signaling pathways on the reprogramming of buffalo PGCs into EG-like cells were investigated. Results showed bFGF to be critical to buffalo PGCs to dedifferentiate into EG-like cells (20 ng/mL is optimal) with many characteristics of pluripotent stem cells, including alkaline phosphatase (AP) activity, expression of pluripotency marker genes such as OCT4, NANOG, SOX2, SSEA-1, CDH1, and TRA-1-81, and the capacity to differentiate into all three embryonic germ layers...
March 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28210447/the-effect-of-different-insertion-techniques-on-the-depth-of-cure-and-vickers-surface-micro-hardness-of-two-bulk-fill-resin-composite-materials
#5
Lamiaa-Mahmoud Moharam, Ahmed-Zohair El-Hoshy, Karim Abou-Elenein
BACKGROUND: The aim of this study was to evaluate the Vickers surface micro-hardness and the depth of cure of two bulk-fill resin composites and one incremental-fill resin composite. MATERIAL AND METHODS: Two Bulk-fill dental resin composites (X-tra Fil, Voco; Sonic-FillTM 2, Kerr Corporation) and an incremental-fill dental resin composite (Filtek™ Z250 XT, 3M ESPE) were used. Sixty cylindrical specimens of 4 mm thickness were prepared using split Teflon moulds...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28208678/novel-fingertip-image-based-heart-rate-detection-methods-for-a-smartphone
#6
Rifat Zaman, Chae Ho Cho, Konrad Hartmann-Vaccarezza, Tra Nguyen Phan, Gwonchan Yoon, Jo Woon Chong
We hypothesize that our smartphone-based fingertip image-based heart rate detection methods reliably detect the heart rhythm and rate of subjects. We propose fingertip curve line movement-based and fingertip image intensity-based detection methods, which both use the movement of successive fingertip images obtained from smartphone cameras. To investigate the performance of the proposed methods, heart rhythm and rate of the proposed methods are compared to those of the conventional method, which is based on average image pixel intensity...
February 12, 2017: Sensors
https://www.readbyqxmd.com/read/28193662/prevalence-and-molecular-characterization-of-mcr-1-positive-salmonella-strains-recovered-from-clinical-specimens-in-china
#7
Mingquan Cui, Jinfei Zhang, Zhen Gu, Ruichao Li, Edward Wai-Chi Chan, Meiyin Yan, Xuebin Xu, Sheng Chen, Congming Wu
The recently discovered colistin resistance-encoding element, mcr-1, adds to the list of antimicrobial resistance genes that rapidly erodes the antimicrobial efficacy of not only the commonly used antibiotics, but also the last line agents of carbapenems and colistin. This study investigated the prevalence of the mobile colistin resistance determinant mcr-1 in Salmonella strains recovered from clinical settings in China, and the transmission potential of mcr-1-bearing mobile elements harbored by such isolates...
February 13, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28191515/medicolegal-implications-of-radial-and-femoral-access-for-coronary-angiography-and-intervention-in-2016-focus-on-retroperitoneal-hemorrhage
#8
Konstantinos V Voudris, Mladen I Vidovich
BACKGROUND AND OBJECTIVES: Retroperitoneal hemorrhage is a rare but serious complication of transfemoral approach (TFA) and TFA percutaneous coronary intervention (PCI). Radial approach for coronary angiography and intervention (transradial approach, TRA) is associated with lower access site complications and reduced blood transfusion rates. Retroperitoneal bleeding has not been described with TRA. This study sought to evaluate the relationship between femoral access for coronary angiography (TFA) and PCI-induced retroperitoneal hemorrhage and the resulting medical litigation in the United States...
April 1, 2016: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/28190734/the-trace-registry-trans-radial-approach-in-central-and-northern-greece
#9
Antonios Ziakas, Sotirios Katranas, Georgios Bobotis, Aggeliki-Despoina Mavrogianni, Christos Graidis, Nikolaos Mezilis, Αntonios Arampatzis, Dimitrios Nikas, Fotios Economou, Ilias Athanasiadis, Dimitrios Stakos, Vasilios Dimopoulos, Eugenia Pappa, Antonios Κouparanis, Dimitrios Petroglou, Haralampos Karvounis
OBJECTIVE: We examined trans-radial approach (TRA) use in coronary angiographies (CAs) as well as in percutaneous coronary interventions (PCIs) in specific regions of Greece, its distribution in public and private catheterization laboratories (CLs) and its preference by operators. Reliable data regarding the use of TRA are not available in Greece. METHODS: The study was performed in northern and central Greece, which constitutes 35.32% of the national population...
November 16, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28189038/the-importance-of-body-mass-normalisation-for-ultrasound-measurement-of-the-transversus-abdominis-muscle-the-effect-of-age-gender-and-sport-practice
#10
Pawel Linek
BACKGROUND: Some studies have not considered body mass as a confounder in TrA analysis, which may have led to improper interpretation of results. OBJECTIVES: To assess the differences in the effect of age, gender and physical activity between normalised for body mass and actual values of the TrA as well as to establish the effect of age, gender and physical activity on normalised for body mass TrA thickness in adolescents. DESIGN: The study was a cross-sectional study conducted at selected primary and secondary schools, and colleges in the Silesian region of Poland...
February 4, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28186489/folding-behavior-of-a-t-shaped-ribosome-binding-translation-enhancer-implicated-in-a-wide-spread-conformational-switch
#11
My-Tra Le, Wojciech K Kasprzak, Taejin Kim, Feng Gao, Megan Yl Young, Xuefeng Yuan, Bruce A Shapiro, Joonil Seog, Anne E Simon
Turnip crinkle virus contains a T-shaped, ribosome-binding, translation enhancer (TSS) in its 3'UTR that serves as a hub for interactions throughout the region. The viral RNA-dependent RNA polymerase (RdRp) causes the TSS/surrounding region to undergo a conformational shift postulated to inhibit translation. Using optical tweezers (OT) and steered molecular dynamic simulations (SMD), we found that the unusual stability of pseudoknotted element H4a/Ψ3 required five upstream adenylates, and H4a/Ψ3 was necessary for cooperative association of two other hairpins (H5/H4b) in Mg(2+)...
February 10, 2017: ELife
https://www.readbyqxmd.com/read/28173931/the-immediate-effects-of-exercise-using-the-functional-re-adaptive-exercise-device-on-lumbopelvic-kinematics-in-people-with-and-without-low-back-pain
#12
A Winnard, D Debuse, M Wilkinson, R Tahmosybayat, N Caplan
BACKGROUND: Dysfunction of the lumbar multifidus (LM) and transversus abdominis (TrA) muscles is associated with low back pain (LBP). The Functional Re-adaptive Exercise Device (FRED) has shown potential as a non-specific LBP intervention by automatically recruiting LM and TrA. Loss or lordosis and altered lumbopelvic positioning has also been linked to LBP and is often trained within LM and TrA interventions. The effect that FRED exercise has on lumbopelvic positioning and lumbar lordosis is unknown...
January 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28165055/human-embryonic-and-induced-pluripotent-stem-cells-maintain-phenotype-but-alter-their-metabolism-after-exposure-to-rock-inhibitor
#13
Spyros I Vernardis, Konstantinos Terzoudis, Nicki Panoskaltsis, Athanasios Mantalaris
Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in colonies to maintain growth and pluripotency. Robust differentiation protocols necessitate single cell cultures that are achieved by use of ROCK (Rho kinase) inhibitors. ROCK inhibition enables maintenance of stem cell phenotype; its effects on metabolism are unknown. hPSCs were exposed to 10 μM ROCK inhibitor for varying exposure times. Pluripotency (TRA-1-81, SSEA3, OCT4, NANOG, SOX2) remained unaffected, until after prolonged exposure (96 hrs)...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28154158/caveolae-provide-a-specialized-membrane-environment-for-respiratory-syncytial-virus-assembly
#14
Alexander Ludwig, Tra Huong Nguyen, Daniel Leong, Laxmi Iyer Ravi, Tan Boon Huan, Sara Sandin, Richard J Sugrue
Respiratory syncytial virus (RSV) is an enveloped virus that assembles into filamentous virus particles on the surface of infected cells. Morphogenesis of RSV is dependent upon cholesterol-rich (lipid raft) membrane microdomains, but the specific role of individual raft molecules in RSV assembly is not well defined. Here we show that RSV morphogenesis occurs within caveolar membranes and that both caveolin-1 and cavin-1, the two major structural and functional components of caveolae, are actively recruited to and incorporated into the RSV envelope...
February 2, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28144910/the-calibrated-phylogeny-of-the-drosophila-fasciola-subgroup-d-repleta-group-wasserman-indicates-neogene-diversification-of-its-internal-branches
#15
F F Franco, E C C Silva, D Y Barrios-Leal, F M Sene, M H Manfrin
The species of the Drosophila fasciola subgroup Wasserman represent the dominant section of the Drosophila repleta group Wasserman in the American rainforests and have a broad geographical distribution in the New World. However, despite of its wide range, the D. fasciola subgroup is one of the most overlooked D. repleta subgroups. Here, we report a molecular phylogenetic analysis focused on the D. fasciola subgroup using two mitochondrial [cytochrome oxidase subunit I (COI), cytochrome oxidase subunit II (COII)] and two nuclear [elongation factor-1alpha F1 (EF-alphaF1) and transformer (tra)] genes...
January 31, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28141511/truncated-forms-of-the-pa-protein-containing-only-the-c-terminal-domains-are-associated-with-the-rnp-complex-within-h1n1-influenza-virus-particles
#16
Myint Myaing, Raihan Jumat, Tra Huong, Boon Huan Tan, Richard J Sugrue
We have examined the expression profile of the influenza virus PA protein in pH1N1/2009 virus-infected cells. Immunoblotting analysis of virus-infected MDCK cells revealed the presence of full-length PA protein from 8 hrs post-infection, together with the simultaneous appearance of PA protein species of approximately 50 kDa, 35/39 kDa and 20/25 kDa (collectively referred to as PA*). PA* was also detected in H1N1/WSN virus-infected cells indicating that its presence was not virus-specific, and PA* was also observed in virus-infected A549 and CEF cells indicating that its presence was not cell type-specific...
January 27, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28138829/metabolism-and-disposition-of-the-anticancer-quinolone-derivative-vosaroxin-a-novel-inhibitor-of-topoisomerase-ii
#17
C M Nijenhuis, L Lucas, H Rosing, A D R Huitema, M Mergui-Roelvink, G C Jamieson, J A Fox, D R Mould, J H M Schellens, J H Beijnen
Background Vosaroxin is a first-in-class anticancer quinolone derivative that is being investigated for patients with relapsed or refractory acute myeloid leukemia (AML). The primary objective of this study was to quantitatively determine the pharmacokinetics of vosaroxin and its metabolites in patients with advanced solid tumors. Methods This mass balance study investigated the pharmacokinetics (distribution, metabolism, and excretion) of vosaroxin in cancer patients after a single dose of 60 mg/m(2 14)C-vosaroxin, administered as short intravenous injection...
January 31, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28119875/effects-of-vojta-method-on-trunk-stability-in-healthy-individuals
#18
Sun-Young Ha, Yun-Hee Sung
Vojta reflex locomotion is important to main upright posture through stimulation of breast zone to patient with cerebral palsy. However, application in other diseases is no investigated. So, we determined the effects of stimulation of the breast zone on trunk stability in healthy individuals. Fourteen young healthy adults (7 males and 7 females) voluntarily participated in this study. The subjects were randomly divided into an experimental group (breast zone) and control group (arbitrary point). All groups were stimulated for 5 min on the left and right sides, respectively, for a total 10 times...
December 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28119043/current-practice-of-transradial-approach-for-coronary-procedures-a-survey-by-the-italian-society-of-interventional-cardiology-sici-gise-and-the-italian-radial-club
#19
Stefano Rigattieri, Orazio Valsecchi, Alessandro Sciahbasi, Francesco Tomassini, Ugo Limbruno, Alfredo Marchese, Alessio La Manna, Ciro Mauro, Ferdinando Varbella, Segio Berti, Fabio F Tarantino, Giuseppe Musumeci
BACKGROUND: Transradial approach (TRA) for percutaneous coronary procedures is associated with improved patient outcome and is being increasingly adopted worldwide. We surveyed Italian interventional cardiologists in order to take a snapshot of the current practice of TRA. METHODS: A web-based questionnaire was emailed to all members of the Italian Society of Interventional Cardiology. RESULTS: The survey was taken by 508 respondents. Cardiogenic shock and chronic total occlusions represented the principal limitations to TRA...
January 17, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28112156/mtorc1-inhibition-in-cancer-cells-protects-from-glutaminolysis-mediated-apoptosis-during-nutrient-limitation
#20
Victor H Villar, Tra Ly Nguyen, Vanessa Delcroix, Silvia Terés, Marion Bouchecareilh, Bénédicte Salin, Clément Bodineau, Pierre Vacher, Muriel Priault, Pierre Soubeyran, Raúl V Durán
A master coordinator of cell growth, mTORC1 is activated by different metabolic inputs, particularly the metabolism of glutamine (glutaminolysis), to control a vast range of cellular processes, including autophagy. As a well-recognized tumour promoter, inhibitors of mTORC1 such as rapamycin have been approved as anti-cancer agents, but their overall outcome in patients is rather poor. Here we show that mTORC1 also presents tumour suppressor features in conditions of nutrient restrictions. Thus, the activation of mTORC1 by glutaminolysis during nutritional imbalance inhibits autophagy and induces apoptosis in cancer cells...
January 23, 2017: Nature Communications
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