Ana Maria Oliveira Ferreira da Mata, Marcia Fernanda Correia Jardim Paz, Ag-Anne Pereira Melo de Menezes, Antonielly Campinho Dos Reis, Bruna da Silva Souza, Carlos Dimas de Carvalho Sousa, Sônia Alves Machado, Thiago Soares Gondim Medeiros, Chandan Sarkar, Muhammad Torequl Islam, Javad Sharifi-Rad, Sevgi Durna Daştan, Mohammed M Alshehri, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo Cavalcante
BACKGROUND: Gastritis is a superficial and prevalent inflammatory lesion that is considered a public health concern once can cause gastric ulcers and gastric cancer, especially when associated with Helicobacter pylori infection. Proton pump inhibitors, such as omeprazole, are the most widely used drugs to treat this illness. The aim of the study was evaluate cytogenetic effects of omeprazole in stomach epithelial cells of patients with gastritis in presence and absence of H. pylori, through cytogenetic biomarkers and catalse and superoxide dismutase analysis...
April 18, 2022: Cancer Cell International