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Conjugated linoleic acid

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https://www.readbyqxmd.com/read/28631807/compositional-analyses-and-shelf-life-modeling-of-njangsa-ricinodendron-heudelotii-seed-oil-using-the-weibull-hazard-analysis
#1
Harold K Abaidoo-Ayin, Prince G Boakye, Kerby C Jones, Victor T Wyatt, Samuel A Besong, Stephen E Lumor
This study investigated the compositional characteristics and shelf-life of Njangsa seed oil (NSO). Oil from Njangsa had a high polyunsaturated fatty acid (PUFA) content of which alpha eleostearic acid (α-ESA), an unusual conjugated linoleic acid was the most prevalent (about 52%). Linoleic acid was also present in appreciable amounts (approximately 34%). Our investigations also indicated that the acid-catalyzed transesterification of NSO resulted in lower yields of α-ESA methyl esters, due to isomerization, a phenomenon which was not observed under basic conditions...
June 20, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28627455/gemcitabine-vitamin-e-conjugates-synthesis-characterization-entrapment-into-nanoemulsions-and-in-vitro-deamination-and-antitumor-activity
#2
Ahmed Abu-Fayyad, Sami Nazzal
Gemcitabine is the first line therapy for pancreatic cancer. It is, however, extensively metabolized to the inactive form by deamination enzymatic reaction. Conjugation of gemcitabine with fatty acids on its 4-amino group was found to protect it from deamination deactivation reaction. The objective of the present study was to test the in-vitro anticancer activity of gemcitabine conjugated to the γ-tocotrienol isomer of vitamin E against pancreatic tumor cells. This objective was based on reported studies in which it was demonstrated that free tocotrienol isomers of vitamin E can potentiate the anticancer activity of gemcitabine...
June 13, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28626143/effect-of-conjugated-linoleic-acid-intake-on-endurance-exercise-performance-and-anti-fatigue-in-student-athletes
#3
Naoko Terasawa, Ken Okamoto, Kenta Nakada, Kazumi Masuda
Conjugated linoleic acids (CLA) intake has been reported to reduce body fat mass or increase lean body mass and to improve exercise outcome by modulating testosterone in humans. These reports have studied mostly overweight subjects; few were athletes. Therefore, in this study, the effect of CLA intake on endurance performance and anti-fatigue in student athletes was investigated. A double-blind, crossover study was conducted with 10 male student athletes. Each subject was administered with either CLA (net 0...
June 13, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28625013/anti-mutagenic-properties-of-mono-and-dienoic-acid-biohydrogenation-products-from-beef-fat
#4
Jeyachchandran Visvalingam, Payam Vahmani, David C Rolland, Michael E R Dugan, Xianqin Yang
Unsaturated fatty acid biohydrogenation products from beef fat and pure fatty acids were subjected to the Ames Salmonella mutagenicity testing, including monounsaturated fatty acids [MUFA: oleic acid, vaccenic acid, elaidic acid; beef fatty acid fractions rich in trans (t)11/t13-t14-18:1 (t11,13,14-Frac), t10-18:1 (t10-Frac)] and dienoic fatty acids [linoleic acid, conjugated linoleic isomers cis (c)9,t11-18:2 and t10,c12-18:2, and a mixed beef dienoic fatty acid fraction high in c9,t13-/t8,c12/t11c15-18:2 (MD)]...
June 17, 2017: Lipids
https://www.readbyqxmd.com/read/28624284/comparing-the-effect-of-homogenization-and-heat-processing-on-the-properties-and-in-vitro-digestion-of-milk-from-organic-and-conventional-dairy-herds
#5
D L Van Hekken, M H Tunick, D X Ren, P M Tomasula
We compared the effects of homogenization and heat processing on the chemical and in vitro digestion traits of milk from organic and conventional herds. Raw milk from organic (>50% of dry matter intake from pasture) and conventional (no access to pasture) farms were adjusted to commercial whole and nonfat milk fat standards, and processed with or without homogenization, and with high-temperature-short-time or UHT pasteurization. The milk then underwent in vitro gastrointestinal digestion. Comparison of milk from organic and conventional herds showed that the milks responded to processing in similar ways...
June 14, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28624283/effect-of-pasture-versus-indoor-feeding-systems-on-quality-characteristics-nutritional-composition-and-sensory-and-volatile-properties-of-full-fat-cheddar-cheese
#6
Tom F O'Callaghan, David T Mannion, Deirdre Hennessy, Stephen McAuliffe, Maurice G O'Sullivan, Natasha Leeuwendaal, Tom P Beresford, Pat Dillon, Kieran N Kilcawley, Jeremiah J Sheehan, R Paul Ross, Catherine Stanton
The purpose of this study was to investigate the effects of pasture-based versus indoor total mixed ration (TMR) feeding systems on the chemical composition, quality characteristics, and sensory properties of full fat Cheddar cheeses. Fifty-four multiparous and primiparous Friesian cows were divided into 3 groups (n = 18) for an entire lactation. Group 1 was housed indoors and fed a TMR diet of grass silage, maize silage, and concentrates; group 2 was maintained outdoors on perennial ryegrass only pasture (GRS); and group 3 was maintained outdoors on perennial ryegrass/white clover pasture (CLV)...
June 14, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28608585/effect-of-dietary-conjugated-linoleic-acid-on-vitamin-a-status-of-lactating-rats-and-their-offspring
#7
J O Zeitz, E Most, K Eder
The absorption and metabolism of vitamin A is linked with that of lipids. It is known that conjugated linoleic acid (CLA) affects the lipid metabolism in growing and lactating animals. In the present study, the hypothesis was investigated that dietary CLA influences vitamin A status of lactating rats and their pups during the suckling period. For this purpose, Wistar Han rats were fed either a control diet (control group, n = 14) or a diet containing 0.87% of cis-9, trans-11 and trans-10, cis-12 (1:1) CLA (CLA group, n = 14) during pregnancy and lactation...
June 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28601449/fatty-acid-profile-of-goat-milk-in-diets-supplemented-with-chia-seed-salvia-hispanica-l
#8
B Schettino, S Vega, R Gutiérrez, A Escobar, J Romero, E Domínguez, M González-Ronquillo
Chia seed (Salvia hispanica L.) is the greatest known plant source of n-3 α-linolenic acid. The present study evaluated the effects of 3 inclusion levels of chia seed [zero (control); low, 2.7% (CLow); and high, 5.5% (CHigh)] in diets of dairy goats on milk yield and fatty acid profile. Nine Saanen dairy goats in the last third of lactation period, live weight 38 ± 8.7 kg, housed in metabolic cages, were fed iso-proteic and iso-energetic (160 g of crude protein/d and 11 MJ of metabolizable energy/d) diets...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28601035/effects-of-dietary-cla-supplementation-parity-and-different-concentrate-levels-before-calving-on-immunoglobulin-g1-g2-and-m-concentrations-in-dairy-cows
#9
Melanie Eger, Jana Horn, Jamal Hussen, Hans-Joachim Schuberth, Maria Scharf, Ulrich Meyer, Sven Dänicke, Hartwig Bostedt, Gerhard Breves
Peripartal dairy cows exhibit a higher susceptibility for infectious diseases, which might be linked to the negative energy balance occurring at the onset of lactation. A dietary supplementation of conjugated linoleic acids (CLA) may reduce milk fat yield and subsequently lower the energy deficit. The utilization of immunoglobulins (Ig) for colostrogenesis might impair humoral immunity in peripartal dairy cows; therefore this study investigated the effects of a CLA supplement, parity and different dietary energy levels on plasma and colostrum IgG1, IgG2 and IgM levels in dairy cows and their calves...
June 2, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28593444/efficacy-of-dietary-supplementation-of-fatty-acid-compound-on-performance-and-production-in-finishing-pigs
#10
Santi Devi Upadhaya, Hyeok Min Yun, Shuaiqi Huang, In Ho Kim
The present study was conducted to evaluate the efficacy of dietary supplementation of 0.5 and 1% of fatty acid (FA) compound containing conjugated linoleic acid as active component on growth performance, apparent nutrient digestibility, serum lipid profile, meat quality, and fatty acid profiles in muscle and adipose tissue in finishing pigs. A total of 90 finishing pigs ([Yorkshire × Landrace] × Duroc) were used in 5-week trial. The growth performance and nutrient digestibility were unaffected with FA supplementation...
June 8, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28592972/fabrication-of-polycaprolactone-polyurethane-loading-conjugated-linoleic-acid-and-its-antiplatelet-adhesion
#11
Ho Hieu Minh, Nguyen Thi Hiep, Nguyen Dai Hai, Vo Van Toi
Polycaprolactone/polyurethane (PCL/PU) fibrous scaffold was loaded with conjugated linoleic acid (CLA) by electrospinning method to improve the hemocompatibility of the polymeric surface. Fourier Transform Infrared Spectroscopy (FT-IR) analysis and Scanning Electron Microscopy (SEM) observation were employed to characterize the chemical structure and the changing morphology of electrospun PCL/PU and PCL/PU loaded with CLA (PCL/PU-CLA) scaffolds. Platelet adhesion and whole blood clot formation tests were used to evaluate the effect of CLA on antithrombotic property of PCL/PU-CLA scaffold...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28559164/pomegranate-seed-oil-influences-the-fatty-acids-profile-and-reduces-the-activity-of-desaturases-in-livers-of-sprague-dawley-rats
#12
Agnieszka Białek, Agnieszka Stawarska, Joanna Bodecka, Małgorzata Białek, Andrzej Tokarz
The aim of our study was to compare the influence of diet supplementation with pomegranate seed oil - as conjugated linolenic acids (CLnA) source, or conjugated linoleic acids (CLA) and to examine the mechanism of their activity. The content of fatty acids, levels of biomarkers of lipids' oxidation and the activity of key enzymes catalyzing lipids metabolism were measured. Obtained results revealed that conjugated fatty acids significantly decrease the activity of Δ5-desaturase (p=0.0001) and Δ6-desaturase (p=0...
May 27, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28556504/effects-of-conjugated-linoleic-acid-supplementation-on-serum-c-reactive-protein-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
REVIEW
Mohsen Mazidi, Ehsan Karimi, Peyman Rezaie, Gordon A Ferns
AIM: To undertake a systematic review and meta-analysis of prospective studies to determine the effect of conjugated linoleic acids (CLAs) supplementation on serum C-reactive protein (CRP). METHOD: PubMed-Medline, Web of Science, Cochrane Database and Google Scholar databases were searched (up until May 2016) to identify prospective studies evaluating the impact of CLAs supplementation on serum CRP. Random effects models meta-analysis was used for quantitative data synthesis...
May 29, 2017: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/28551180/effect-of-dietary-quebracho-tannin-extract-on-milk-fatty-acid-composition-in-cows
#14
Anika Henke, Edwin Westreicher-Kristen, Joachim Molkentin, Uta Dickhoefer, Karin Knappstein, Mario Hasler, Andreas Susenbeth
The aim of this study was to examine the capacity of quebracho tannin extract (QTE) to modulate the fatty acid (FA) profile in the milk fat of cows. Fifty Holstein cows yielding 33.2 ± 8.2 kg/d of milk were divided into 2 groups. The cows were fed a basal diet with a forage-concentrate ratio of 66:34 on a dry matter (DM) basis. Diets tested were control (CON, basal diet without QTE) and basal diet plus 15 or 30 g of QTE/kg of DM (QTE15 and QTE30, respectively). Two treatments could be tested simultaneously and were arranged along 6 periods...
May 24, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28547181/sequential-feeding-of-lipid-supplement-enriches-beef-adipose-tissues-with-18-3n-3-biohydrogenation-intermediates
#15
P Vahmani, J L Aalhus, D C Rolland, T A McAllister, N Prieto, H C Block, S D Proctor, L L Guan, M E R Dugan
The present study was designed to determine if feeding steers extruded flaxseed and hay (25 and 75%; DM basis) together as a total mixed ration (TMR), or sequentially (non-TMR) would result in different enrichments of polyunsaturated fatty acids (PUFA) and their biohydrogenation intermediates (BHI) in beef adipose tissues [subcutaneous (SC) vs perirenal (PR) fat]. Forty-eight Angus cross steers (325 ± 16 kg) were stratified by weight to six pens, and pens were randomized to either TMR or non-TMR and fed ad libitum for an average of 242 days...
May 25, 2017: Lipids
https://www.readbyqxmd.com/read/28540041/effects-of-quantitative-feed-restriction-and-sex-on-carcass-traits-meat-quality-and-meat-lipid-profile-of-morada-nova-lambs
#16
Thiago L A C de Araújo, Elzânia S Pereira, Ivone Y Mizubuti, Ana C N Campos, Marília W F Pereira, Eduardo L Heinzen, Hilton C R Magalhães, Leilson R Bezerra, Luciano P da Silva, Ronaldo L Oliveira
BACKGROUND: An experiment was conducted to evaluate the effects of feed restriction (FR) and sex on the quantitative and qualitative carcass traits of Morada Nova lambs. Thirty-five animals with an initial body weight of 14.5 ± 0.89 kg and age of 120 d were used in a completely randomized study with a 3 × 3 factorial scheme consisting of three sexes (11 entire males, 12 castrated males and 12 females) and three levels of feeding (ad libitum - AL and 30% and 60% FR). RESULTS: Entire males presented greater hot and cold carcass weights (P < 0...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28523042/effect-of-conjugated-linoleic-acid-supplementation-on-quality-of-life-in-rectal-cancer-patients-undergoing-preoperative-chemoradiotherapy
#17
Elnaz Faramarzi, Reza Mahdavi, Mohammad Mohammad-Zadeh, Behnam Nasirimotlagh, Sarvin Sanaie
OBJECTIVES: This study set out with the aim of evaluating the effect of conjugated linoleic acid (CLA) supplementation on quality of life in rectal cancer patients undergoing to preoperative chemoradiotherapy. METHODS: In this study, 33 volunteer patients with rectal cancer treated with preoperative chemoradiotherapy were allocated in the CLA (n=16) and the placebo groups (n=17). The CLA group and placebo groups received 3 gr CLA/d and 4 placebo capsules for 6 weeks respectively...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28521988/enhanced-solubility-and-antioxidant-activity-of-chlorogenic-acid-chitosan-conjugates-due-to-the-conjugation-of-chitosan-with-chlorogenic-acid
#18
Liyun Rui, Minhao Xie, Bing Hu, Li Zhou, Muhammad Saeeduddin, Xiaoxiong Zeng
Chlorogenic acid-chitosan conjugate was synthesized by introducing of chlorogenic acid onto chitosan with the aid of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and hydroxybenzotriazole. The data of UV-vis, FT-IR and NMR for chlorogenic acid-chitosan conjugates demonstrated the successful conjugation of chlorogenic acid with chitosan. Compared to chitosan, chlorogenic acid-chitosan conjugates exhibited increased solubility in distilled water, 1% acetic acid solution (v/v) or 50% ethanol solution (v/v) containing 0...
August 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28521607/intravenous-fish-oil-and-pediatric-intestinal-failure-associated-liver-disease-changes-in-plasma-phytosterols-cytokines-and-bile-acids-and-erythrocyte-fatty-acids
#19
Kara L Calkins, Andrea DeBarber, Robert D Steiner, Martiniano J Flores, Tristan R Grogan, Susanne M Henning, Laurie Reyen, Robert S Venick
BACKGROUND: Soybean oil (SO) emulsions are associated with intestinal failure-associated liver disease (IFALD); fish oil (FO) emulsions are used to treat IFALD. SO and FO differ with respect to their fatty acid and phytosterol content. In children with IFALD whose SO was replaced with FO, we aimed to (1) quantify changes in erythrocyte fatty acids and plasma phytosterols, cytokines, and bile acids and (2) correlate these changes with direct bilirubin (DB). DESIGN: This study enrolled IFALD children who received 6 months of FO...
May 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28507012/dietary-factors-promoting-brown-and-beige-fat-development-and-thermogenesis
#20
REVIEW
Meshail Okla, Jiyoung Kim, Karsten Koehler, Soonkyu Chung
Brown adipose tissue (BAT) is a specialized fat tissue that has a high capacity to dissociate cellular respiration from ATP utilization, resulting in the release of stored energy as heat. Adult humans possess a substantial amount of BAT in the form of constitutively active brown fat or inducible beige fat. BAT activity in humans is inversely correlated with adiposity, blood glucose concentrations, and insulin sensitivity; this suggests that strategies aimed at BAT-mediated bioenergetics are an attractive therapeutic target in combating the continuing epidemic of obesity and diabetes...
May 2017: Advances in Nutrition
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