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https://www.readbyqxmd.com/read/28428591/educational-webinars-with-free-verifiable-cpd
#1
(no author information available yet)
No abstract text is available yet for this article.
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28422605/time-to-first-cigarette-physical-activity-and-pulmonary-function-in-middle-aged-to-older-adult-smokers
#2
Russell T Nye, Melissa Mercincavage, Steven A Branstette
BACKGROUND: How addiction severity relates to physical activity (PA), and if PA moderates the relation between PA and lung function among smokers is unknown. This study explored the independent and interactive associations of nicotine addiction severity and PA with lung function. METHODS: The study utilized cross-sectional data from 343 adult smokers aged 40-79 participating in the 2009-10 and 2011-12 National Health and Nutrition Examination Survey. Assessed were the independent relations of nicotine addiction severity, as measured by the time to first cigarette (TTFC), and average daily minutes of moderate and vigorous PA with lung function ratio (FEV1/FVC)...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28421951/mindfulness
#3
Toni McIntosh
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The CPD article discussed mindfulness and self-compassion, and how these concepts can improve nurses' well-being and their ability to provide compassionate care.
April 19, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28416011/which-learning-activities-enhance-physiotherapy-practice-a-systematic-review-protocol-of-quantitative-and-qualitative-studies
#4
Edmund Leahy, Lucy Chipchase, Felicity Blackstock
BACKGROUND: Learning activities are fundamental for the development of expertise in physiotherapy practice. Continuing professional development (CPD) encompasses formal and informal learning activities undertaken by physiotherapists. Identifying the most efficient and effective learning activities is essential to enable the profession to assimilate research findings and improve clinical skills to ensure the most efficacious care for clients. To date, systematic reviews on the effectiveness of CPD provide limited guidance on the most efficacious models of professional development for physiotherapists...
April 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28409381/dash-type-cryptochromes-regulate-fruiting-body-development-and-secondary-metabolism-differently-than-cmwc-1-in-the-fungus-cordyceps-militaris
#5
Fen Wang, Xinhua Song, Xiaoming Dong, Jiaojiao Zhang, Caihong Dong
Cryptochromes (CRYs) belong to the photolyase/cryptochrome flavoprotein family, which is widely distributed in all kingdoms. A phylogenetic analysis indicated that three Cordyceps militaris proteins [i.e., cryptochrome DASH (CmCRY-DASH), (6-4) photolyase, and cyclobutane pyrimidine dimer (CPD) class I photolyase] belong to separate fungal photolyase/cryptochrome subfamilies. CmCRY-DASH consists of DNA photolyase and flavin adenine dinucleotide-binding domains, with RGG repeats in a C-terminal extension. Considerably, more carotenoids and cordycepin accumulated in the ΔCmcry-DASH strain than in the wild-type or ΔCmwc-1 strains, indicating an inhibitory role for CmCRY-DASH in these biosynthetic pathways...
April 13, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28405480/contrast-sensitivity-in-microtropic-and-anisometropic-eyes-of-successfully-treated-amblyopes
#6
Özlem Öner, Sezin Akça Bayar, Sibel Oto, Onur Gökmen, Mustafa Agah Tekindal
OBJECTIVES: To assess and compare contrast sensitivity function in the previously amblyopic and non-amblyopic "normal" eyes of patients with microtropia and anisometropia who achieved 20/20 visual acuity after occlusion therapy. MATERIALS AND METHODS: Contrast sensitivity was tested monocularly on both eyes of 34 successfully treated microtropic and 15 anisometropic subjects (visual acuity 20/20 in both eyes). Contrast sensitivity function was evaluated by CSV-1000E and age-matched nomograms were used (spatial frequencies of 3, 6, 12, and 18 cycles per degree [cpd]) for comparison...
April 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28403475/cigarette-smoking-during-pregnancy-do-complete-abstinence-and-low-level-cigarette-smoking-have-similar-impact-on-birth-weight
#7
Ivan Berlin, Jean-Louis Golmard, Nelly Jacob, Marie-Laure Tanguy, Stephen J Heishman
Objectives: Despite awareness of negative health outcomes associated with smoking, pregnant smokers might reduce their tobacco consumption thinking that a low smoking rate reduces smoking-related negative birth outcomes. We aimed to assess in a clinical sample whether there is a smoking rate that would not impact on birth weight (BW). Methods: Pregnant smokers ≥18 years, gestational age of 9-20 weeks of amenorrhea, motivated to quit smoking, smoking ≥5 cigarettes/day (cpd) and their newborns (381 singleton, live births) were included in this secondary analysis of a French smoking cessation trial...
May 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28399759/reporting-poor-care
#8
Ruth Beretta
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article discussed raising concerns and reporting poor care in practice. It explained the difference between making errors and poor care, and outlined the moral, professional and legal obligations nurses have to report instances of poor care.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28397108/prevalence-and-function-of-heschl-s-gyrus-morphotypes-in-musicians
#9
Jan Benner, Martina Wengenroth, Julia Reinhardt, Christoph Stippich, Peter Schneider, Maria Blatow
Morphological variations of the first transverse Heschl's gyrus (HG) in the human auditory cortex (AC) are common, yet little is known about their functional implication. We investigated individual morphology and function of HG variations in the AC of 41 musicians, using structural and functional magnetic resonance imaging (fMRI) as well as magnetoencephalography (MEG). Four main morphotypes of HG were (i) single HG, (ii) common stem duplication (CSD), (iii) complete posterior duplication (CPD), and (iv) multiple duplications (MD)...
April 10, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28395691/march-2017-cpd-question-13
#10
C Naidu
No abstract text is available yet for this article.
March 29, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28393477/residues-at-a-single-site-differentiate-animal-cryptochromes-from-cyclobutane-pyrimidine-dimer-photolyases-by-affecting-the-proteins-preferences-for-reduced-fad
#11
Lei Xu, Bin Wen, Yuan Wang, Changqing Tian, Mingcai Wu, Guoping Zhu
Cryptochromes (CRYs) and photolyases belong to the cryptochrome/photolyase family (CPF). Reduced FAD is essential for photolyases to photorepair UV induced cyclobutane pyrimidine dimers (CPDs) or 6-4 photoproducts in DNA. In Drosophila CRY (dCRY, a type I animal CRY), FAD is converted to the anionic radical but not to the reduced state during illumination, which may induce a conformational change in the protein to relay the light signal downstream. To explore the foundation of these differences, multiple sequence alignment of 650 CPF protein sequences was performed...
April 10, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28390541/improving-continuing-professional-development-opportunities-for-radiographers-a-single-centre-evaluation
#12
Barry J Stevens, Demetri Wade
PURPOSE: This study aimed to identify current barriers to CPD and generate ideas for strategies to overcome these issues. Further aims were to gather an overview of respondents' understanding and opinions of CPD. METHODS: An online survey was used to acquire information from departmental band 5 and band 6 radiographers. Descriptive statistical analysis and thematic analysis were performed to understand demographics and individuals' behaviours and experiences. FINDINGS: Radiographers (n = 33) were sent an invitation via email providing a response rate of 75...
May 2017: Radiography
https://www.readbyqxmd.com/read/28387522/mechanism-of-cytochrome-p450-17a1-catalyzed-hydroxylase-and-lyase-reactions
#13
Silvia Bonomo, Flemming Steen Jørgensen, Lars Olsen
Cytochrome P450 17A1 (CYP17A1) catalyzes C17 hydroxylation of pregnenolone and progesterone and the subsequent C17-C20 bond cleavage (lyase reaction) to form androgen precursors. Compound I (Cpd I) and peroxo anion (POA) are the heme-reactive species underlying the two reactions. We have characterized the reaction path for both the hydroxylase and lyase reactions using density functional theory (DFT) calculations and the enzyme-substrate interactions by molecular dynamics (MD) simulations. Activation barriers for positions subject to hydroxylase reaction have values close to each other and span from 54 to 60 kJ·mol(-1) with a small preference for 17α hydroxylation, in agreement with experimental observations...
April 19, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28386186/mechanistic-prediction-of-food-effects-for-compound-a-tablet-using-pbpk-model
#14
Xueqing Li, Lei Shi, Xiuling Tang, Qinghui Wang, Lun Zhou, Wei Song, Zhijun Feng, Jie Ge, Jian Kang Li, Lin Yang, Aidong Wen, Yan Zhang
Physiologically based pharmacokinetic (PBPK) modeling has been extensively used to study the factors of effect drug absorption, distribution, metabolize and extraction progress in human. In this study, Compound A(CPD A) is a BCS Class II drug, which has been extensive applied in clinical as lipid-lowering drug, administered orally after food, they displayed positive food effects in human, A PBPK model was built to mechanistic investigate the food effect of CPD A tablet in our study. By using gastroplus™ software, the PBPK models accurately predicted the results of food effects and predicted data were within 2-fold error of the observed results...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28378667/adverse-drug-reactions
#15
Georgina O'Reilly-Foley
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The CPD article defined the different types of adverse drug reactions (ADRs) and explored when they can occur. It emphasised the importance of being knowledgeable about medications, considering patient safety when patients are taking medications, being alert to the possibility of ADRs, and recognising and responding to suspected ADRs.
April 5, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28371900/cigarette-nicotine-content-as-a-moderator-of-the-relationship-between-negative-affect-and-smoking
#16
Jason D Robinson, George Kypriotakis, Maher Karam-Hage, Charles E Green, Dorothy K Hatsukami, Paul M Cinciripini, Eric C Donny
Introduction: Research suggests a strong association between negative affect and smoking. However, little is known about the association between negative affect and smoking among individuals who switch to reduced-nicotine cigarettes. The goal of this study was to examine the extent to which cigarette nicotine content moderates the relationship between negative affect and smoking over time. Methods: 717 participants, 237 in the normal nicotine content (NNC; 15.8 mg/g and usual brand) cigarette group and 480 in the very low nicotine content (VLNC; 2...
March 22, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28371857/association-of-the-dbh-polymorphism-rs3025343-with-smoking-cessation-in-a-large-population-based-sample
#17
Katariina Hirvonen, Tellervo Korhonen, Veikko Salomaa, Satu Männistö, Jaakko Kaprio
Introduction: Genetic variations in DBH-gene and its surroundings have been shown to associate with smoking behavior including smoking cessation in several studies. In this study we replicate and measure the effect size for association between DBH polymorphism rs3025343 and smoking cessation in a large population-based sample while examining environmental factors that could relate to the association. Methods: We studied 11,926 adult subjects from four surveys of the National FINRISK Study...
March 22, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28371856/population-modeling-of-modified-risk-tobacco-products-accounting-for-smoking-reduction-and-gradual-transitions-of-relative-risk
#18
Bill Poland, Florian Teischinger
Introduction: As suggested by the Food and Drug Administration (FDA) Modified Risk Tobacco Product (MRTP) Applications Draft Guidance, we developed a statistical model based on public data to explore the effect on population mortality of an MRTP resulting in reduced conventional cigarette smoking. Many cigarette smokers who try an MRTP persist as dual users while smoking fewer conventional cigarettes per day (CPD). Lower-CPD smokers have lower mortality risk based on large cohort studies...
March 27, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28364216/prolactin-androgen-inducible-carboxypeptidase-d-increases-with-nitrotyrosine-and-ki67-for-breast-cancer-progression-in-vivo-and-upregulates-progression-markers-vegf-c-and-runx2-in-vitro
#19
Lynn N Thomas, Emily R Chedrawe, Penelope J Barnes, Catherine K L Too
PURPOSE: Carboxypeptidase-D (CPD) cleaves C-terminal arginine (Arg) to produce nitric oxide (NO). Upregulation of CPD and NO by 17β-estradiol, prolactin (PRL), and androgen increases survival of human breast cancer (BCa) cells in vitro. To demonstrate similar events in vivo, CPD, nitrotyrosine (NT, hallmark of NO action), androgen receptor (AR), prolactin receptor (PRLR), and phospho-Stat5a (for activated PRLR) levels were evaluated in benign and malignant human breast tissues, and correlated with cell proliferation (Ki67) and BCa progression (Cullin-3) biomarkers...
March 31, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28364085/northern-ireland-s-young-vets-host-impressive-yvn-event
#20
(no author information available yet)
Laura Carleton, BVA member services and policy support officer, reports on a recent CPD event held in Northern Ireland for young graduates in the region.
April 1, 2017: Veterinary Record
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