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https://www.readbyqxmd.com/read/28643286/identifying-primary-care-physicians-continuing-education-needs-by-examining-clinical-practices-attitudes-and-barriers-to-screening-across-multiple-cancers
#1
Brenna Lynn, Alexandra Hatry, Chloe Burnett, Lisa Kan, Tunde Olatunbosun, Bob Bluman
Population-based cancer screening for cervical, breast, and colorectal cancers improves patient outcomes, yet screening rates remain low for some cancers. Despite studies investigating physician perceptions and practices for screening, many have focused on individual cancers and lack primary care physicians' (PCPs) realities around screening for multiple cancers. We surveyed 887 PCPs in British Columbia (BC) to examine practices, beliefs, barriers, and learning needs towards cancer screening across breast, cervical, colorectal, prostate, as well as hereditary predisposition to cancer...
June 22, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28642097/are-two-dimensional-measured-frontal-plane-angles-related-to-three-dimensional-measured-kinematic-profiles-during-running
#2
Bart Dingenen, Filip F Staes, Lieselot Santermans, Lien Steurs, Maarten Eerdekens, Jurre Geentjens, Koen H E Peers, Maarten Thysen, Kevin Deschamps
OBJECTIVES: To investigate the temporal relationship between two-dimensional measured frontal plane joint angles and three-dimensional measured kinematic profiles during the stance phase of running, and to assess the intra- and intertester reliability of the two-dimensional angles. DESIGN: Observational study. SETTING: Research laboratory. PARTICIPANTS: Fifteen injury-free elite athletes. MAIN OUTCOME MEASURES: Contralateral pelvic drop (CPD), femoral adduction (FA), hip adduction (HA) and knee valgus (KV) were measured at the deepest landing position during midstance with two-dimensional video analysis during running...
March 4, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28639448/-hybrid-monovision
#3
P Studený, M Kacerovský, J Kacerovská, N Gajarová, Z Straňák
AIM: To evaluate our own results of the use of hybrid monovision technique, in patients after bilateral cataract surgery, where in the dominant eye the monofocal intraocular lens is implanted and in the non-dominant eye the multifocal intraocular lens (IOL) is implanted. MATERIAL AND METHODS: Prospective follow-up of group of 33 patients with bilateral cataract surgery and induced hybrid monovision. In the dominant eye, the hydrophilic monofocal aspheric intraocular lens Auroflex (Aurolab) was implanted, and in the non-dominant eye the hydrophilic multifocal aspheric intraocular lens Seelens (Hanita) was implanted...
2017: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/28635452/reflective-practice
#4
Lynda Kenny
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article focused on reflection, which is an essential tool for nurses that can be used in their personal and professional development, while reinforcing continuous learning.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28628900/evaluation-of-the-innotyper-%C3%A2-21-genotyping-kit-in-multi-ethnic-populations
#5
Peter Gustav Ristow, Nicole Barnes, Gina Pineda Murphy, Hiromi Brown, Kevin Wesley Cloete, Maria Eugenia D'Amato
We report the findings of the evaluation of the InnoTyper(®) 21 genotyping kit for the use of human identification (HID) and paternity testing in South Africa. This novel forensic kit evaluates 20 retrotransposable elements (AC4027, MLS26, ALU79712, NBC216, NBC106, RG148, NBC13, AC2265, MLS09, AC1141, TARBP, AC2305, HS4.69, NBC51, ACA1766, NBC120, NBC10, NBC102, SB19.12 and NBC148) and the Amelogenin locus for sex determination. The evaluation of the genotyping performance showed no significant spectral pull-up for peak heights between 100 and 30,000 RFUs...
June 7, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28628631/computational-explanation-for-bioactivation-mechanism-of-targeted-anticancer-agents-mediated-by-cytochrome-p450s-a-case-of-erlotinib
#6
Chun-Zhi Ai, Yong Liu, Wei Li, De-Meng Chen, Xin-Xing Zhu, Ya-Wei Yan, Du-Chu Chen, Yi-Zhou Jiang
EGFR inhibitors, even with therapeutics superiorities in anticancer, can cause idiosyncratic pulmonary and hepatic toxicities that are associated with the reactive electrophile bioactivated by Cytochrome P450s (P450s). Until now, neither has the electrophilic intermediate been caught experimentally, nor has the subtle mechanism been declared. Herein, the underlying mechanism of bioactivation mediated by P450s was explored by DFT calculations for a case of EGFR inhibitor, Erlotinib. Based on the calculation and analysis, we suggest that with other metabolites, reactive electrophiles of Erlotinib: epoxide and quinine-imine, can be generated by several steps along the oxidative reaction pathway...
2017: PloS One
https://www.readbyqxmd.com/read/28626821/mesopic-visual-quality-after-accelerated-corneal-cross-linking-a-12-month-follow-up-study
#7
Hassan Hashemi, Soheila Asgari
PURPOSE: To determine the 1-year changes of mesopic higher order aberrations (HOAs) and contrast sensitivity (CS) after accelerated corneal cross linking (CXL) in progressive keratoconus. METHODS: In this prospective case series, 70 eyes of 62 keratoconic patients underwent accelerated CXL (18 mW/cm(2), 5 min). HOAs and CS were measured using the OPD Scan III and CSV-1000 CS test charts under mesopic conditions before and 6 and 12 months after CXL. RESULTS: At 1 year, logarithmic mesopic CS in spatial frequencies of 3, 6, 12, and 18 cycles per degree (CPD) had increased by 0...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28612643/survey-of-irish-general-practitioners-preferences-for-continuing-professional-development
#8
B Maher, R O'Neill, A Faruqui, C Bergin, M Horgan, D Bennett, C M P O'Tuathaigh
BACKGROUND: Doctors' continuing professional development (CPD) training needs are known to be strongly influenced by national and local contextual characteristics. Given the changing national demographic profile and government-mandated changes to primary care health care provision, this study aimed to investigate Irish General Practitioners' (GPs) perceptions of, and preferences for, current and future CPD programmes. METHODS: A cross-sectional questionnaire, using closed- and open-ended questions, was administered to Irish GPs, focusing on training needs analysis; CPD course content; preferred format and the learning environment...
June 14, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28612509/acceptability-of-peer-clinical-observation-by-faculty-members
#9
Joshua Borus, Sarah Pitts, Holly Gooding
BACKGROUND: Most doctors are not observed in the actual practice of medicine after they complete training. Direct observation and feedback are seen as invaluable in learning in most other professions, at formative stages of medical training and in other aspects of academic medicine, yet are not performed at the level of the independently practicing clinician. Creating an opportunity for faculty member development based on observation of clinical practice is needed for continued growth and competence as a clinician...
June 14, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28612497/pharmacotherapy-follow-up-role-in-active-malaria-surveillance-in-a-travel-medicine-centre-outside-the-transmission-area-in-brazil
#10
R S Pedro, P Brasil, A Pina-Costa, C R Machado, L S Damasceno, C T Daniel-Ribeiro, L Guaraldo
WHAT IS KNOWN AND OBJECTIVE: Malaria is a potentially severe disease, widespread in tropical and subtropical areas. Apart from parasite drug resistance, which receives the largest share of attention, several factors directly influence the response to antimalarial treatment such as incorrect doses, adverse drug events, lack of adherence to treatment, drug quality and drug-drug interactions. Pharmacotherapy follow-up can be used to monitor and improve the effectiveness of treatment, prevent drug-related problems and ensure patient safety...
June 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28610511/mindfulness
#11
Georgina O'Reilly-Foley
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article discussed how mindfulness and self-compassion can enhance compassionate care. At a time when the NHS is under increased pressure and media scrutiny, it was useful to read about strategies that support nurses to manage this pressure and maintain high standards of care.
June 14, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28609415/effect-of-povidone-iodine-5-on-the-cornea-vision-and-subjective-comfort
#12
William H Ridder, Caren Oquindo, Kavita Dhamdhere, James Burke
PURPOSE: To determine the effects of povidone iodine 5% (Betadine 5%) applied to the eye on visual function, corneal integrity, and subjective complaints. METHODS: Ten subjects were chosen to participate in this study (average age 40.6 ± 19.6; age range 22-68). LogMAR acuity, contrast sensitivity, corneal fluorescein staining, and subjective complaints were measured before and after 60 μl of Betadine 5% or saline were applied to one eye (eligibility visit, baseline, 5, 30, and 60 minutes and 4 and 24 hours post-application)...
June 10, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28604768/rosetta-msf-a-modular-framework-for-multi-state-computational-protein-design
#13
Patrick Löffler, Samuel Schmitz, Enrico Hupfeld, Reinhard Sterner, Rainer Merkl
Computational protein design (CPD) is a powerful technique to engineer existing proteins or to design novel ones that display desired properties. Rosetta is a software suite including algorithms for computational modeling and analysis of protein structures and offers many elaborate protocols created to solve highly specific tasks of protein engineering. Most of Rosetta's protocols optimize sequences based on a single conformation (i. e. design state). However, challenging CPD objectives like multi-specificity design or the concurrent consideration of positive and negative design goals demand the simultaneous assessment of multiple states...
June 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28603394/what-do-you-need-to-know-to-set-up-cpd-as-a-professional-body
#14
Helena P Filipe, Karl Golnik, Daksha Patel
No abstract text is available yet for this article.
2017: Community Eye Health
https://www.readbyqxmd.com/read/28603393/how-to-do-cpd-with-your-team-from-the-organisation-s-perspective
#15
Dhivya Ramasamy, Suzanne S Gilbert
No abstract text is available yet for this article.
2017: Community Eye Health
https://www.readbyqxmd.com/read/28603392/how-to-figure-out-what-cpd-cme-you-need
#16
Milka Mafwiri, Nick Astbury
No abstract text is available yet for this article.
2017: Community Eye Health
https://www.readbyqxmd.com/read/28603390/how-the-rcophth-cpd-system-works
#17
Alex Tytko
No abstract text is available yet for this article.
2017: Community Eye Health
https://www.readbyqxmd.com/read/28600372/a-mixed-methods-evaluation-of-the-educational-supervision-agreement-for-wales
#18
Katie Louise Webb, Alison Bullock, Caroline Groves, Anton Gerhard Saayman
OBJECTIVES: In a bid to promote high-quality postgraduate education and training and support the General Medical Council's (GMC) implementation plan for trainer recognition, the Wales Deanery developed the Educational Supervision Agreement (EdSA). This is a three-way agreement between Educational Supervisors, Local Education Providers and the Wales Deanery which clarifies roles, responsibilities and expectations for all. This paper reports on the formative evaluation of the EdSA after 1 year...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28600257/search-for-more-effective-microsatellite-markers-for-forensics-with-next-generation-sequencing
#19
Bowen Tan, Zicheng Zhao, Zhe Zhang, Shengbin Li, Shuai Cheng Li
Published by the Combined DNA Index System (CODIS) program of the Federal Bureau of Investigation (FBI) in 1997, the 13 core short tandem repeat (STR) loci are widely adopted as genetic markers in forensic applications, e.g., identity testing and paternity testing. However, these loci may be biased and suffer from reduced sensitivities towards specific population groups. In addition, the rapid growth of entries in forensic databases raises the chance of random hits, which can cause false recognitions of criminal suspects...
June 7, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28599158/degradation-of-highly-consumed-fluoroquinolones-penicillins-and-cephalosporins-in-distilled-water-and-simulated-hospital-wastewater-by-uv254-and-uv254-persulfate-processes
#20
Efraím A Serna-Galvis, Franklin Ferraro, Javier Silva-Agredo, Ricardo A Torres-Palma
In this work, three penicillins (ampicillin "AMP", oxacillin "OXA" and cloxacillin "CLO"), two cephalosporins (cephalexin "CPX" and cephadroxyl "CPD") and three fluoroquinolones (levofloxacin "LEV", norfloxacin "NOR" and ciprofloxacin "CIP") were initially treated by UV254 and persulfate activated by UV254 (UV/PS). Significant differences in degradation kinetics under UV254 irradiation were found. Photodegradation followed the order: OXA > CPX > CPD > CLO > CIP > NOR > AMP ≫ LEV...
June 1, 2017: Water Research
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