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https://www.readbyqxmd.com/read/28530160/eagle-syndrome-a-case-report-of-stylocarotid-syndrome-with-internal-carotid-artery-dissection
#1
Travis W Smoot, Ammar Taha, Nicholas Tarlov, Blake Riebe
Eagle syndrome is defined by an elongated styloid process or a calcified stylohyoid ligament that impinges on surrounding structures and causes a variety of symptoms. Classically, Eagle syndrome presents as neck, throat, or ear pain. The vascular variant, stylocarotid syndrome, can present as headache, transient ischemic attack, or stroke. Carotid artery dissection is a rare complication of stylocarotid syndrome. We report a case of stylocarotid syndrome in a 60-year-old man who presented with a right internal carotid artery (ICA) dissection and focal neurological deficits...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28526085/papillary-fibroelastoma-unusual-cause-of-stroke-in-a-young-man-a-case-report
#2
Elisabetta Grolla, Michele Dalla Vestra, Giampaolo Zoffoli, Riccardo D'Ascoli, Adriana Critelli, Rocco Quatrale, Domenico Mangino, Fausto Rigo
BACKGROUND: Papillary fibroelastoma is the third most common primary benign tumor with an incidence of up to 0.33% in autopsy series; it accounts for approximately 75% of all cardiac valvular tumors. CASE PRESENTATION: We describe a rare case of a 28-Year-old man that while playing football, had a sudden onset of neurological deficit: aphasia, right hemiparesis and right facial numbness. Transthoracic echocardiography (TTE) showed a 10x10 mm mass attached to the anterior mitral valve leaflet...
May 19, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28513255/successful-mechanical-thrombectomy-in-a-comatose-patient-with-cerebral-venous-sinus-thrombosis-a-case-report
#3
Merel Jj Verhagen, Adriaan Cgm van Es, Geert J Lycklama À Nijeholt, Korné Jellema, Jonathan Coutinho, Ido R van den Wijngaard
Cerebral venous sinus thrombosis is a rare cause of stroke, which is routinely treated with systemic heparin. Unfavourable outcome is often seen in severe cases. Therefore alternative treatment methods should be explored in these patients. Due to the risk of haemorrhagic complications, treatment without administration of thrombolytics is of particular interest. This report presents a case of successful mechanical thrombectomy, without the use of thrombolytics, in a comatose patient with cerebral venous sinus thrombosis...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28500274/combined-hmg-coa-reductase-and-prenylation-inhibition-in-treatment-of-ccm
#4
Sayoko Nishimura, Ketu Mishra-Gorur, JinSeok Park, Yulia V Surovtseva, Said M Sebti, Andre Levchenko, Angeliki Louvi, Murat Gunel
Cerebral cavernous malformations (CCMs) are common vascular anomalies that develop in the central nervous system and, more rarely, the retina. The lesions can cause headache, seizures, focal neurological deficits, and hemorrhagic stroke. Symptomatic lesions are treated according to their presentation; however, targeted pharmacological therapies that improve the outcome of CCM disease are currently lacking. We performed a high-throughput screen to identify Food and Drug Administration-approved drugs or other bioactive compounds that could effectively suppress hyperproliferation of mouse brain primary astrocytes deficient for CCM3...
May 12, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28489279/dipeptidyl-peptidase-dpp-4-inhibitors-and-glucagon-like-peptide-glp-1-analogues-for-prevention-or-delay-of-type-2-diabetes-mellitus-and-its-associated-complications-in-people-at-increased-risk-for-the-development-of-type-2-diabetes-mellitus
#5
REVIEW
Bianca Hemmingsen, David P Sonne, Maria-Inti Metzendorf, Bernd Richter
BACKGROUND: The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could develop into a substantial health problem worldwide. Whether dipeptidyl-peptidase (DPP)-4 inhibitors or glucagon-like peptide (GLP)-1 analogues are able to prevent or delay T2DM and its associated complications in people at risk for the development of T2DM is unknown. OBJECTIVES: To assess the effects of DPP-4 inhibitors and GLP-1 analogues on the prevention or delay of T2DM and its associated complications in people with impaired glucose tolerance, impaired fasting blood glucose, moderately elevated glycosylated haemoglobin A1c (HbA1c) or any combination of these...
May 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28489124/retroauricular-pain-caused-by-eagle-syndrome-a-rare-presentation-due-to-compression-by-styloid-process-elongation
#6
Aline Lariessy Campos Paiva, João Luiz Vitorino Araujo, Renan Maximilian Lovato, Joel Augusto Ribeiro Teixeira, Flávio Key Miura, Vinicius Monteiro de Paula Guirado, José Carlos Esteves Veiga
Eagle syndrome is a rare condition presenting with retroauricular pain (usually as main symptom) associated with dysphagia, headache, neck pain on rotation and, much rarelier, stroke. This occurs due to styloid process elongation. Sometimes, there is also styloid ligament calcification, which can cause compression of nerves and arteries and the symptoms above. Treatment can be conservative with pain modulators (e.g. pregabalin) or infiltrations (steroids or anesthetics drugs). In refractory cases, surgical approach aiming to reduce the size of the styloid process can be performed...
March 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28487744/atorvastatin-diltiazem-combination-induced-rhabdomyolysis-leading-to-diagnosis-of-hypothyroidism
#7
N D B Ehelepola, S M B Y Sathkumara, H M P A G S Bandara, K L R Kalupahana
Statins and hypothyroidism, independently, can rarely cause rhabdomyolysis. The combination of them especially with concurrent intake of drugs such as diltiazem increases the risk of rhabdomyolysis. Hashimoto's encephalopathy is a rare condition associated with Hashimoto's thyroiditis and some patients with that can present with a stroke like picture. An elderly male who has been on atorvastatin for three years and on diltiazem for a week presented with sudden onset inability to walk and confusion. On examination muscle tenderness was noticed and creatine kinase levels indicated rhabdomyolysis which we attributed to atorvastatin...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28486967/pseudoxanthoma-elasticum
#8
REVIEW
Dominique P Germain
Pseudoxanthoma elasticum (PXE) is a genetic metabolic disease with autosomal recessive inheritance caused by mutations in the ABCC6 gene. The lack of functional ABCC6 protein leads to ectopic mineralization that is most apparent in the elastic tissues of the skin, eyes and blood vessels. The clinical prevalence of PXE has been estimated at between 1 per 100,000 and 1 per 25,000, with slight female predominance. The first clinical sign of PXE is almost always small yellow papules on the nape and sides of the neck and in flexural areas...
May 10, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28479449/symptomatic-carotid-bulb-atypical-fibromuscular-dysplasia
#9
D Verscheure, D Fabre, D Smadja, E Fadel
Fibromuscular Dysplasia (FMD) is known as rare cause ischemic stroke, and usually involves the internal carotid or vertebral arteries in middle age women. A poorly known type of FMD located at the carotid bulb is called atypical fibromuscular dysplasia.
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28476103/intracranial-lesion-as-onset-symptom-in-a-patient-with-early-undifferentiated-connective-tissue-disease-a-case-report
#10
Ying Du, Chuan Li, Dai-di Zhao, Jia-Rui Lu, Wei Zhang, Zhu-Yi Li
BACKGROUND: Undifferentiated connective tissue disease (UCTD) is widely considered to be a distinct clinical entity, and now divided into two subgroups: stable UCTD and early UCTD. The most frequent onset symptoms of UCTD include arthralgias, arthritis, Raynaud's phenomenon, mucocutaneous involvement, and sicca symptoms. However, Neurologic involvement is rare, and intracranial lesion as onset symptom in a patient with early UCTD has not yet been reported. CASE PRESENTATION: A 51-year-old Chinese female experienced progressive left leg weakness for 14 days before hospitalizing in our department...
May 5, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28473801/cerebrovascular-manifestations-of-lyme-neuroborreliosis-a-systematic-review-of-published-cases
#11
REVIEW
Adam Garkowski, Joanna Zajkowska, Agata Zajkowska, Alina Kułakowska, Olga Zajkowska, Bożena Kubas, Dorota Jurgilewicz, Marcin Hładuński, Urszula Łebkowska
BACKGROUND: Lyme neuroborreliosis (LNB) is a disease caused by spirochete Borrelia burgdorferi, involving the nervous system. It usually manifests as lymphocytic meningoradiculitis, but in rare cases, it can also lead to cerebrovascular complications. We aimed to perform a systematic review of all reported cases of LNB complicated by central nervous system vasculitis and stroke or transient ischemic attack (TIA). MATERIALS AND METHODS: We conducted a systematic review of literature between May 1987 and December 2016 with patients who presented with cerebrovascular course of LNB...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28458950/carotid-cavernous-fistula-after-percutaneous-balloon-compression-for-trigeminal-neuralgia-endovascular-treatment-with-coils
#12
Luana A M Gatto, Rafaella Tacla, Gelson L Koppe, Zeferino Demartini Junior
BACKGROUND: Percutaneous ganglyolysis treatment of trigeminal neuralgia is rarely associated with vascular complications, such as hematoma, subarachnoid hemorrhage, and stroke. Internal carotid artery injury may also occur after misguided needle placement, particularly far posteriorly or medially, resulting in carotid cavernous fistula. Anatomical variations of the foramen ovale can predispose those complications. CASE DESCRIPTION: A young woman diagnosed with trigeminal neuralgia during 11 years was submitted to a balloon rhizotomy by percutaneous approach to the trigeminal ganglion, with severe intraoperative bleeding...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28458927/papillary-fibroelastoma-as-a-cause-of-cardiogenic-embolic-stroke-in-a-%C3%AE-thalassemia-patient-case-report-and-literature-review
#13
Re-I Chin, John J Monda, Maulik Sheth, William Ogle, Gloria Merenda, Debapriya De
We describe a case of a young male without stroke risk factors who presented with a sudden onset of left-sided weakness, left hand numbness, and left eye blurriness. CT scan of the head without contrast and diffusion-weighted MRI of the brain with contrast revealed an ischemic stroke in the right middle cerebral artery distribution. Transesophageal echocardiography (TEE) revealed a mobile pedunculated mass on the posterior surface of the mitral valve. This mass was resected and pathology showed a cardiac papillary fibroelastoma (CPFE), which was determined to be the cause of the patient's cardioembolic stroke...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28451018/infective-endocarditis-in-principal-hospital-of-dakar-a-retrospective-study-of-42-cases-over-10-years
#14
Djibril Marie Ba, Mouhamed Cherif Mboup, Nafissatou Zeba, Khadidiatou Dia, Awa Ndaw Fall, Fatou Fall, Pape Diadie Fall, Sara Boury Gning
Infective Endocarditis (IE) is an endocardial infection usually caused by bacteria that affects not only the native heart valves but also, with increasing frequency intravascular implanted devices and congenital heart diseases. Despite medical advances, IE remains a life-threatening disease with substantial morbidity and mortality. In Africa, its diagnosis and treatment are still a major challenge in clinical practice. The objective of this work was to study the epidemiological, clinical features, diagnostic techniques currently used in medical practice and the range of micro-organisms that are responsible...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28447493/m2-segment-dissection-of-middle-cerebral-artery-diagnosed-using-high-resolution-magnetic-resonance-imaging
#15
Xiaoyan Song, Haiyan Lv, Jianjun Tang, Qing Zhang, Qiaoshu Wang
Middle cerebral artery (MCA) dissection is a rare cause of ischemic stroke, especially in the M2 or M3 segments. Diagnosis of intracranial artery dissection remains challenging. We herein report a case of M2 segment dissection of the MCA with typical features of an intimal flap and intramural hematoma diagnosed using high-resolution 3T magnetic resonance imaging. This imaging technique might be a more effective noninvasive method by which to diagnose M2 segment dissection of the MCA than either computed tomography angiography or digital subtraction angiography...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28438894/flow-diverter-treatment-of-intracranial-vertebral-artery-dissecting-pseudoaneurysms
#16
REVIEW
Russell Cerejo, Mark Bain, Nina Moore, Julian Hardman, Andrew Bauer, M Shazam Hussain, Thomas Masaryk, Peter Rasmussen, Gabor Toth
INTRODUCTION: Intracranial vertebral dissecting pseudoaneurysms are a rare, but increasingly recognized, cause of subarachnoid hemorrhage and ischemic stroke. The risks of aneurysm re-rupture and associated morbidity are high. The use of flow diverter stents for the treatment of these aneurysms has not been well studied. OBJECTIVE: To report our data and provide a summarized review of literature using flow diverter stents for the treatment of intracranial vertebral artery dissecting pseudoaneurysms...
April 24, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28431954/isolated-intracranial-fibromuscular-dysplasia-of-the-posterior-cerebral-artery
#17
Min-Ju Yeo, Ho-Yeong Jeon, Min-Ju Cha, Hye-Yeon Jang, Sang-Gil Lee, Ji Seon Kim, Sung-Hyun Lee, Sang-Soo Lee, Dong-Ick Shin
Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory arterial disease that most commonly affects the renal and internal carotid arteries, but intracranial FMD is very rare. We report a patient with FMD involving the posterior cerebral arteries (PCAs). A 24year old female was presented with a 4day history of right homonymous hemianopsia with throbbing headache in the left temporo-occipital area. The brain magnetic resonance imaging (MRI) revealed an acute ischemic stroke in the left PCA territory, while the Time of Flight (TOF) magnetic resonance angiogram (MRA) showed segmental luminal irregularities in the left proximal PCA...
April 18, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28408257/ischemic-stroke-in-young-adults-with-moyamoya-disease-prognostic-factors-for-stroke-recurrence-and-functional-outcome-after-revascularization
#18
Meng Zhao, Xiaofeng Deng, Faliang Gao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Jizong Zhao
OBJECTIVE: Stroke in young adults is uncommon and have rarely been described. Moyamoya disease is one of the leading causes of stroke in young adults. We aimed to study the prognostic factors for stroke recurrences and functional outcomes in young stroke patients with moyamoya disease after revascularization. METHODS: We reviewed 696 consecutive patients with moyamoya disease admitted to our hospital from 2009 to 2015 and identified patients aged 18-45 years with first-ever stroke...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28400981/new-developments-in-the-pathophysiology-workup-and-diagnosis-of-dural-venous-sinus-thrombosis-dvst-and-a-systematic-review-of-endovascular-treatments
#19
REVIEW
Sanjay Konakondla, Clemens M Schirmer, Fengwu Li, Xiaogun Geng, Yuchuan Ding
Dural venous sinus thrombosis (DVST) is a rare cause of stroke, which typically affects young women. The importance of identifying pre-disposing factors that lead to venous stasis lies in the foundation of understanding the etiology, pathophysiology and clinical presentation. The precise therapeutic role of interventional therapies is not fully understood though the current data do suggest potential applications. The aim of the study was to perform a systematic review and meta-analysis to evaluate the utility of and short-term 30-day survival after endovascular therapy for patients with DVST...
April 2017: Aging and Disease
https://www.readbyqxmd.com/read/28400903/neurosarcoidosis-presenting-with-recurrent-strokes-a-case-report-and-literature-review
#20
Naheed Raza, Karisa C Schreck
Neurosarcoidosis is a rare but important cause of stroke as it is treatable. Cases reported thus far have primarily been in young people who are relatively healthy. Here we report the case of a 73-year-old woman presenting with recurrent strokes and high-grade intracranial stenosis caused by probable neurosarcoidosis. This is unique as neurosarcoidosis is not usually considered as an etiology for recurrent strokes in our patient's age-group. We review and categorize published cases of neurosarcoidosis causing stroke and describe a classification scheme for certainty of diagnosis...
April 2017: Neurohospitalist
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