Aislinn Low, Brendan Stiltner, Yaira Z Nunez, Keyrun Adhikari, Joseph D Deak, Robert H Pietrzak, Henry R Kranzler, Joel Gelernter, Renato Polimanti
There is a high prevalence of antisocial personality disorder (ASPD) in individuals affected by substance use disorders (SUD). However, there is limited information on the specific patterns of association of ASPD with SUD severity and specific SUD diagnostic criteria. We investigated the association of alcohol, cannabis, cocaine, opioid, and tobacco use disorders (AUD, CanUD, CocUD, OUD, and TUD, respectively) in 1,660 individuals with ASPD and 6,640 controls matched by sex (24% female), age, and racial/ethnic background in a sample ascertained for addiction-related traits...
September 15, 2023: medRxiv