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https://www.readbyqxmd.com/read/29353341/field-of-view-normalization-in-multi-site-brain-mri
#1
Yangming Ou, Lilla Zöllei, Xiao Da, Kallirroi Retzepi, Shawn N Murphy, Elizabeth R Gerstner, Bruce R Rosen, P Ellen Grant, Jayashree Kalpathy-Cramer, Randy L Gollub
Multi-site brain MRI analysis is needed in big data neuroimaging studies, but challenging. The challenges lie in almost every analysis step including skull stripping. The diversities in multi-site brain MR images make it difficult to tune parameters specific to subjects or imaging protocols. Alternatively, using constant parameter settings often leads to inaccurate, inconsistent and even failed skull stripping results. One reason is that images scanned at different sites, under different scanners or protocols, and/or by different technicians often have very different fields of view (FOVs)...
January 20, 2018: Neuroinformatics
https://www.readbyqxmd.com/read/29352643/assessment-of-a-source-position-checking-tool-for-the-quality-assurance-of-transfer-tubes-used-in-hdr-192ir-brachytherapy-treatments
#2
O A Awunor
PURPOSE: The determination of source positions before treatment is an essential part of the quality assurance (QA) associated with high dose rate brachytherapy treatments. The purpose of this study was to design and commission a tool to allow the quantification of source positions across multiple transfer tube types. METHODS AND MATERIALS: A bespoke flexi-adapter jig, three transfer tube adapters, and a film piercing pointer were designed and built for source position QA across three transfer tube types-the standard, 6 French, and gynae transfer tubes...
January 15, 2018: Brachytherapy
https://www.readbyqxmd.com/read/29352627/indications-and-limits-of-stereoelectroencephalography-seeg
#3
REVIEW
Lorella Minotti, Alexandra Montavont, Julia Scholly, Louise Tyvaert, Delphine Taussig
Epilepsy surgery is now an accepted treatment to achieve seizure control in carefully selected patients, both children and adults, suffering from drug-resistant focal epilepsy. Although surgical strategies can often be defined on the basis of non-invasive diagnostic procedures, and despite the recent advances in this field, an increasing number of more complex cases requires invasive EEG (iEEG) to provide precise information on the localization of the epileptogenic zone (EZ), its relationships with eloquent cortex (EC), and the feasibility of a tailored surgical resection...
January 15, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29352228/dual-band-metamaterial-antenna-for-lte-bluetooth-wimax-system
#4
Md Mehedi Hasan, Mohammad Rashed Iqbal Faruque, Mohammad Tariqul Islam
A compact metamaterial inspired antenna operate at LTE, Bluetooth and WiMAX frequency band is introduced in this paper. For the lower band, the design utilizes an outer square metallic strip forcing the patch to radiate as an equivalent magnetic-current loop. For the upper band, another magnetic current loop is created by adding metamaterial structure near the feed line on the patch. The metamaterial inspired antenna dimension of 42 × 32 mm2 compatible to wireless devices. Finite integration technique based CST Microwave Studio simulator has been used to design and numerical investigation as well as lumped circuit model of the metamaterial antenna is explained with proper mathematical derivation...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29351853/cardiac-biomarkers-as-sensitive-tools-to-evaluate-the-impact-of-xenobiotics-on-amphibians-the-effects-of-anionic-surfactant-linear-alkylbenzene-sulfonate-las
#5
Monica Jones-Costa, Lilian Franco-Belussi, Felipe Augusto Pinto Vidal, Nathália Penteado Gongora, Luciano Mendes Castanho, Cleoni Dos Santos Carvalho, Elaine Cristina Mathias Silva-Zacarin, Fabio Camargo Abdalla, Iolanda Cristina Silveira Duarte, Classius De Oliveira, Cristiane Ronchi de Oliveira, Raquel Fernanda Salla
Amphibian populations have been experiencing a drastic decline worldwide. Aquatic contaminants are among the main factors responsible for this decline, especially in the aquatic environment. The linear alkylbenzene sulfonate (LAS) is of particular concern, since it represents 84% of the anionic surfactants' trade. In Brazil, the maximal LAS concentration allowed in fresh waters is 0.5mgL-1, but its potential harmful effects in amphibians remain unknown. Therefore, this study aimed to analyze the effects of a sublethal concentration of LAS (0...
January 16, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29350628/inkjet-printing-and-electrical-characterisation-of-dna-templated-cadmium-sulfide-nanowires
#6
Raushan Nurdillayeva, Atsinafe Oshido, Thomas Bamford, Osama El-Zubir, Andrew Houlton, John Hedley, Andrew Pike, Benjamin Horrocks
Cadmium sulfide can be templated on -DNA molecules to form an aqueous dispersion of CdS/-DNA nanowires. Subsequent addition of ethylene glycol to 50% v/v is sufficient to formulate an ink suitable for printing using piezoelectric drop-on-demand technology. Printed droplet arrays show a coffee-ring morphology of individual deposits by fluorescence and Raman microscopy, but upon increasing the number of layers of printed material by repeated printing over each droplet, the dry deposit approaches closer to a disc shape...
January 19, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29350466/simultaneous-extraction-and-determination-of-trace-amounts-of-diclofenac-from-whole-blood-using-supported-liquid-membrane-microextraction-and-fast-fourier-transform-voltammetry
#7
Zahra Mofidi, Parviz Norouzi, Masumeh Sajadian, Mohammad Reza Ganjali
A novel, simple and inexpensive analytical technique based on flat sheet supported liquid membrane microextraction coupled with fast Fourier transform stripping cyclic voltammetry on a reduced graphene oxide carbon paste electrode was used for the extraction and online determination of diclofenac in whole blood. First, diclofenac was extracted from blood samples using a polytetrafluoroethylene membrane impregnated with 1-octanol and then into an acceptor solution, subsequently it was oxidized on a carbon paste electrode modified with reduced graphene oxide nano-sheets...
January 19, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29349998/-comparative-study-of-minimally-invasive-percutaneous-pedicle-screw-fixation-and-open-surgery-in-the-treatment-of-thoracolumbar-fractures
#8
Hui Ye, Qi-Xin Chen
OBJECTIVE: To compare the clinical outcomes of minimally invasive percutaneous pedicle screw fixation and open surgery in the treatment of thoracolumbar fracture. METHODS: A retrospective study of patients who had undergone surgery for thoracolumbar fracture from June 2014 to December 2014 was performed. Sixty-one cases were included and 29 cases were treated by minimally invasive percutaneous pedicle screw fixation (minimally invasive group) and 32 cases were treated by the traditional open pedicle screw fixation(open group)...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29347937/monoclonal-antibody-based-colloid-gold-immunochromatographic-strip-for-the-rapid-detection-of-tomato-zonate-spot-tospovirus
#9
Yanbing Niu, Defu Wang, Liyan Cui, Baoxia Wang, Xiaojing Pang, Peixia Yu
BACKGROUND: Tomato zonate spot virus (TZSV), a new species of genus Tospovirus, caused significant losses in yield and problems in quality of many important vegetables and ornamentals in Southwest China and posed a serious threat to important economic crops for the local farmers. A convenient and reliable method was urgently needed for rapid detection and surveillance of TZSV. METHODS: The nucleocapsid protein (N) of TZSV was expressed in Escherichia coli and purified, and was used as the antigen to immunize BALB/c mice...
January 18, 2018: Virology Journal
https://www.readbyqxmd.com/read/29347742/exact-solution-of-the-hidden-markov-processes
#10
David B Saakian
We write a master equation for the distributions related to hidden Markov processes (HMPs) and solve it using a functional equation. Thus the solution of HMPs is mapped exactly to the solution of the functional equation. For a general case the latter can be solved only numerically. We derive an exact expression for the entropy of HMPs. Our expression for the entropy is an alternative to the ones given before by the solution of integral equations. The exact solution is possible because actually the model can be considered as a generalized random walk on a one-dimensional strip...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347696/stochastic-dynamics-of-genetic-broadcasting-networks
#11
Davit A Potoyan, Peter G Wolynes
The complex genetic programs of eukaryotic cells are often regulated by key transcription factors occupying or clearing out of a large number of genomic locations. Orchestrating the residence times of these factors is therefore important for the well organized functioning of a large network. The classic models of genetic switches sidestep this timing issue by assuming the binding of transcription factors to be governed entirely by thermodynamic protein-DNA affinities. Here we show that relying on passive thermodynamics and random release times can lead to a "time-scale crisis" for master genes that broadcast their signals to a large number of binding sites...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347574/emergence-of-biaxial-nematic-phases-in-solutions-of-semiflexible-dimers
#12
Arvin Vaghela, Paulo I C Teixeira, Eugene M Terentjev
We investigate the isotropic, uniaxial nematic and biaxial nematic phases, and the transitions between them, for a model lyotropic mixture of flexible molecules consisting of two rigid rods connected by a spacer with variable bending stiffness. We apply density-functional theory within the Onsager approximation to describe strictly excluded-volume interactions in this athermal model and to self-consistently find the orientational order parameters dictated by its complex symmetry, as functions of the density...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29344335/glycemic-control-among-primary-care-patients-with-type-2-diabetes-mellitus-in-the-gaza-strip-palestine
#13
Mahmoud Radwan, Aymen Elsous, Hasnaa Al-Sharif, Ayman Abu Mustafa
Aim: In this study, we aimed to assess the level of good glycemic control, to determine association between adherence to antidiabetic medications and glycosylated hemoglobin (HbA1c) and to examine factors influencing good glycemic control. Materials and methods: A cross-sectional design was employed among 369 patients with type 2 diabetes mellitus (T2DM) from four Ministry of Health health centers in 2016. A sample of 3 ml blood was taken to measure the HbA1c, and patients were asked to fill out a pretested questionnaire...
January 2018: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29343770/reconstructing-the-gradient-source-position-from-steady-state-fluxes-to-small-receptors
#14
Ulrich Dobramysl, David Holcman
Recovering the position of a source from the fluxes of diffusing particles through small receptors allows a biological cell to determine its relative position, spatial localization and guide it to a final target. However, how a source can be recovered from point fluxes remains unclear. Using the Narrow Escape approach for an open domain, we compute the diffusion fluxes of Brownian particles generated by a steady-state gradient from a single source through small holes distributed on a surface in two dimensions...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343631/stochastic-resonances-in-a-distributed-genetic-broadcasting-system-the-nf%C3%AE%C2%BAb-i%C3%AE%C2%BAb-paradigm
#15
Zhipeng Wang, Davit A Potoyan, Peter G Wolynes
Gene regulatory networks must relay information from extracellular signals to downstream genes in an efficient, timely and coherent manner. Many complex functional tasks such as the immune response require system-wide broadcasting of information not to one but to many genes carrying out distinct functions whose dynamical binding and unbinding characteristics are widely distributed. In such broadcasting networks, the intended target sites are also often dwarfed in number by the even more numerous non-functional binding sites...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29342883/development-of-sic-nanoparticles-and-second-phases-synergistically-reinforced-mg-based-composites-processed-by-multi-pass-forging-with-varying-temperatures
#16
Kaibo Nie, Yachao Guo, Kunkun Deng, Xiaojun Wang, Kun Wu
In this study, SiC nanoparticles were added into matrix alloy through a combination of semisolid stirring and ultrasonic vibration while dynamic precipitation of second phases was obtained through multi-pass forging with varying temperatures. During single-pass forging of the present composite, as the deformation temperature increased, the extent of recrystallization increased, and grains were refined due to the inhibition effect of the increasing amount of dispersed SiC nanoparticles. A small amount of twins within the SiC nanoparticle dense zone could be found while the precipitated phases of Mg17Al12 in long strips and deformation bands with high density dislocations were formed in the particle sparse zone after single-pass forging at 350 °C...
January 13, 2018: Materials
https://www.readbyqxmd.com/read/29339064/factors-associated-with-early-graft-detachment-in-primary-descemet-membrane-endothelial-keratoplasty
#17
Pia Leon, Mohit Parekh, Yoav Nahum, Michael Mimouni, Giuseppe Giannaccare, Laura Sapigni, Alessandro Ruzza, Massimo Busin
PURPOSE: To evaluate the risk factors for early graft detachment in Descemet Membrane Endothelial Keratoplasty (DMEK). DESIGN: Case-control Study. METHODS: ▪ PARTICIPANTS: 173 donor corneas and 173 eyes of the patients following DMEK or DMEK in combination with phacoemulsification and IOL implantation were included. INTERVENTION: Pre-stripped DMEK grafts were transplanted using pull-through technique. At the end of surgery, the anterior chamber was filled with air, which was removed 3 hours later only if pupillary block was suspected...
January 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29338196/a-method-for-high-frequency-underway-n2-fixation-measurements-flow-through-incubation-acetylene-reduction-assays-by-cavity-ring-down-laser-absorption-spectroscopy-faracas
#18
Nicolas Cassar, Weiyi Tang, Hans Gabathuler, Kuan Huang
Because of the difficulty in resolving the large variability of N2 fixation with current methods which rely on discrete sampling, the development of new methods for high resolution measurements is highly desirable. We present a new method for high-frequency measurements of aquatic N2 fixation by continuous flow-through incubations and spectral monitoring of the acetylene (C2H2, a substrate analog for N2) reduction to ethylene (C2H4). In this method, named "Flow-through incubation Acetylene Reduction Assays by Cavity ring-down laser Absorption Spectros-copy" (FARACAS), dissolved C2H2 is continuously admixed with seawater upstream of a continuous-flow stirred-tank reactor (CFSR) in which C2H2 reduction takes place...
January 17, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29338010/gypsophila-bermejoi-g-l%C3%A3-pez-a-possible-case-of-speciation-repressed-by-bioclimatic-factors
#19
Miguel de Luis, Carmen Bartolomé, Óscar García Cardo, Julio Álvarez-Jiménez
Gypsophila bermejoi G. López is an allopolyploid species derived from the parental G. struthium L. subsp. struthium and G. tomentosa L. All these plants are gypsophytes endemic to the Iberian Peninsula of particular ecological, evolutionary and biochemical interest. In this study, we present evidence of a possible repression on the process of G. bermejoi speciation by climatic factors. We modelled the ecological niches of the three taxa considered here using a maximum entropy approach and employing a series of bioclimatic variables...
2018: PloS One
https://www.readbyqxmd.com/read/29337913/proteomic-analysis-and-identification-of-possible-allergenic-proteins-in-mature-pollen-of-populus-tomentosa
#20
Liuqiang Wang, Xiaoling Zhang, Jin Zhang, Wei Fan, Mengzhu Lu, Jianjun Hu
Pollen grains from Populus tomentosa, a widely cultivated tree in northern area of China, are considered to be an important aeroallergen causing severe allergic diseases. To gain insight into their allergenic components, mature Populus tomentosa pollen proteins were analyzed by two-dimensional gel electrophoresis (2-DE) and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF/TOF MS). A total of 412 spots from mature pollen were resolved on pH 4-7 immobilized pH gradient (IPG) strips and 159 distinct proteins were identified from 242 spots analyzed...
January 16, 2018: International Journal of Molecular Sciences
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