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https://www.readbyqxmd.com/read/28454043/vacuum-scanning-capillary-photoemission-microscopy
#1
S A Aseyev, A P Cherkun, B N Mironov, V V Petrunin, S V Chekalin
We demonstrate the use of a conical capillary in a scanning probe microscopy for surface analysis. The probe can measure photoemission from a substrate by transmitting photoelectrons along the capillary as a function of probe position. The technique is demonstrated on a model substrate consisting of a gold reflecting layer on a compact disc which has been illuminated by an unfocused laser beam with a wavelength 400nm, from a femtosecond laser with a beam size of 4mm. A quartz capillary with a 2-µm aperture has been used in the experiments...
April 19, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/28449032/comparing-outcomes-and-cost-of-3-surgical-treatments-for-sagittal-synostosis-a-retrospective-study-including-procedure-related-cost-analysis
#2
Sarah T Garber, Michael Karsy, John R W Kestle, Faizi Siddiqi, Stephen P Spanos, Jay Riva-Cambrin
BACKGROUND: Neurosurgical techniques for repair of sagittal synostosis include total cranial vault (TCV) reconstruction, open sagittal strip (OSS) craniectomy, and endoscopic strip (ES) craniectomy. OBJECTIVE: To evaluate outcomes and cost associated with these 3 techniques. METHODS: Via retrospective chart review with waiver of informed consent , the last consecutive 100 patients with sagittal synostosis who underwent each of the 3 surgical correction techniques before June 30, 2013, were identified...
April 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28448536/lateral-flow-immunoassay-for-on-site-detection-of-xanthomonas-arboricola-pv-pruni-in-symptomatic-field-samples
#3
Pablo López-Soriano, Patricia Noguera, María Teresa Gorris, Rosa Puchades, Ángel Maquieira, Ester Marco-Noales, María M López
Xanthomonas arboricola pv. pruni is a quarantine pathogen and the causal agent of the bacterial spot disease of stone fruits and almond, a major threat to Prunus species. Rapid and specific detection methods are essential to improve disease management, and therefore a prototype of a lateral flow immunoassay (LFIA) was designed for the detection of X. arboricola pv. pruni in symptomatic field samples. It was developed by producing polyclonal antibodies which were then combined with carbon nanoparticles and assembled on nitrocellulose strips...
2017: PloS One
https://www.readbyqxmd.com/read/28446460/inhibition-of-cholinergic-neurotransmission-by-%C3%AE-3-adrenoceptors-depends-on-adenosine-release-and-a1-receptors-activation-in-human-and-rat-urinary-bladders
#4
Isabel Silva, Ana Filipa Costa, Sílvia Moreira, Fátima Ferreirinha, Maria Teresa Magalhães-Cardoso, Isabel Calejo, Miguel Silva-Ramos, Paulo Correia-de-Sá
The direct detrusor relaxant effect of β3-adrenoceptor agonists as a primary mechanism to improve overactive bladder symptoms has been questioned. Among other targets, activation of β3-adrenoceptors down-modulate nerve-evoked acetylcholine (ACh) release, but there is insufficient evidence for the presence of these receptors on bladder cholinergic nerve terminals. Our hypothesis is that adenosine formed from the catabolism of cyclic AMP in the detrusor may act as a retrograde messenger via prejunctional A1 receptors to explain inhibition of cholinergic activity by β3-adrenoceptors...
April 26, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28446246/the-role-of-rk39-serologic-test-in-the-diagnosis-of-visceral-leishmaniasis-in-a-tertiary-hospital-northern-ethiopia
#5
Yazezew Kebede Kiros, Bethlhem Feleke Regassa
BACKGROUND: The study is done in Ayder Referral Hospital in Northern Ethiopia. Ethiopia is one of the countries where visceral leishmaniasis (VL) is endemic. Diagnosis of VL in Ethiopia is primarily based on rK39 immunochromatographic (rk39-ICT) strip. This test has been shown to have variable sensitivity and specificity in different countries. Hence the objective of the study is to determine the sensitivity and specificity of rk39-ICT in the diagnosis of VL in our set up. The study participants were VL suspected patients admitted to the hospital...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446019/a-novel-fusion-bead-procedure-for-nuclear-forensics-employing-synthetic-enstatite-to-dissolve-uraniferous-and-other-challenging-materials-prior-to-la-icp-ms
#6
David G Reading, Ian W Croudace, Phillip Edward Warwick
There is an increasing demand for rapid and effective analytical tools to support nuclear forensic investigations of seized or suspect materials. Some methods are simply adapted from other scientific disciplines and can effectively be used to rapidly prepare complex materials for subsequent analysis. A novel sample fusion method is developed, tested and validated to produce homogeneous, flux-free glass beads of geochemical reference materials (GRMs), uranium ores, and uranium ore concentrates (UOC) prior to the analysis of 14 rare earth elements (REE) via LA-ICP-MS...
April 27, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28444988/inhibitory-action-of-oxytocin-on-spontaneous-contraction-of-rat-distal-colon-by-nitrergic-mechanism-involvement-of-cyclic-gmp-and-apamin-sensitive-k-channels
#7
R Wang, M T Han, X L Lv, Y A Yu, S Q Chai, C M Qu, C Y Liu
AIM: The mechanisms underlying the inhibitory effects of oxytocin (OT) on colon tone are not totally understood. We explore the mechanisms of OT on spontaneous contractility in rat distal colon, and identify the mediators involved in this action. METHODS: In rat distal colon strips, mechanical activity was analyzed and the production of nitric oxide (NO) in tissue loaded with the fluorochrome DAF-FM was visualized by confocal microscopy. OT receptor (OTR) expression was determined by western blotting and immunofluorescence...
April 26, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28444428/commentary-reduction-malarplasty-that-uses-malar-setback-without-resection-of-malar-body-strip
#8
Michael J Yaremchuk, Jeffrey H Lee
No abstract text is available yet for this article.
April 25, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28441321/a-cost-effective-relative-humidity-sensor-based-on-side-coupling-induction-technology
#9
Yingzi Zhang, Yulong Hou, Wenyi Liu, Huixin Zhang, Yanjun Zhang, Zhidong Zhang, Jing Guo, Jia Liu, Liang Zhang, Qiu-Lin Tan
A intensity-modulated optical fiber relative humidity (RH) sensor based on the side coupling induction technology (SCIT) is presented and experimentally demonstrated. The agarose gel and the twisted macro-bend coupling structure are first combined for RH sensing applications. The refractive index (RI) of the agarose gel increases with the increase of the RH and is in linear proportion from 20 to 80%RH. The side coupling power, which changes directly with the RI of the agarose gel, can strip the source noise from the sensor signal and improve the signal to noise ratio substantially...
April 25, 2017: Sensors
https://www.readbyqxmd.com/read/28440659/alleviation-of-multiple-asthmatic-pathologic-features-with-orally-available-and-subtype-selective-gabaa-receptor-modulators
#10
Gloria S Forkuo, Amanda N Nieman, Nina Y Yuan, Revathi Kodali, Olivia B Yu, Nicolas M Zahn, Rajwana Jahan, Guanguan Li, Michael Rajesh Stephen, Margaret L Guthrie, Michael M Poe, Benjamin D Hartzler, Ted William Harris, Gene T Yocum, Charles W Emala, Douglas A Steeber, Douglas C Stafford, James M Cook, Leggy A Arnold
We describe pharmacokinetic and pharmacodynamic properties of two novel oral drug candidates for asthma. Phenolic α4β3γ2 GABAAR selective compound 1 and acidic α5β3γ2 selective GABAAR positive allosteric modulator compound 2 relaxed airway smooth muscle ex vivo and attenuated airway hyperresponsiveness (AHR) in a murine model of asthma. Importantly, compound 2 relaxed acetylcholine contracted human tracheal airway smooth muscle strips. Oral treatment of compound 1 and 2 decreased eosinophils in bronchoalveolar lavage fluid in ovalbumin sensitized and challenged mice, thus exhibiting anti-inflammatory properties...
April 25, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28440299/a-reversible-dendrite-free-high-areal-capacity-lithium-metal-electrode
#11
Hui Wang, Masaki Matsui, Hiroko Kuwata, Hidetoshi Sonoki, Yasuaki Matsuda, Xuefu Shang, Yasuo Takeda, Osamu Yamamoto, Nobuyuki Imanishi
Reversible dendrite-free low-areal-capacity lithium metal electrodes have recently been revived, because of their pivotal role in developing beyond lithium ion batteries. However, there have been no reports of reversible dendrite-free high-areal-capacity lithium metal electrodes. Here we report on a strategy to realize unprecedented stable cycling of lithium electrodeposition/stripping with a highly desirable areal-capacity (12 mAh cm(-2)) and exceptional Coulombic efficiency (>99.98%) at high current densities (>5 mA cm(-2)) and ambient temperature using a diluted solvate ionic liquid...
April 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28440248/descemet-stripping-automated-endothelial-keratoplasty
#12
Namrata Sharma, Prafulla K Maharana, Shipra Singhi, Neelima Aron, Mukesh Patil
Endothelial keratoplasty is at present the gold standard for surgical treatment of corneal endothelial pathologies not associated with significant corneal scar. Tremendous progress has been made in recent years in improving the technology of endothelial keratoplasty techniques, such as descemet stripping automated endothelial keratoplasty (DSAEK) and descemet membrane endothelial keratoplasty. In this review, we discuss the current techniques and outcomes of DSAEK.
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440226/calibration-phantoms-for-accurate-water-and-lipid-density-quantification-using-dual-energy-mammography
#13
Hyo-Min Cho, Huanjun Ding, Nikita Kumar, David Sennung, Sabee Molloi
The aim of this study is to investigate the feasibility of water and lipid as calibration phantoms for accurate dual energy breast density quantification. Dual energy calibration was performed on a mammography system based on scanning multi-slit Si strip photon-counting detectors using plastic water and adipose-equivalent phantoms as the basis materials. Two different methods were used to convert the dual energy decomposition measurements in plastic phantom thicknesses into the true water and lipid basis materials...
April 25, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28440060/a-practical-approach-in-bioreactor-scale-up-and-process-transfer-using-a-combination-of-constant-p-v-and-vvm-as-the-criterion
#14
Sen Xu, Linda Hoshan, Rubin Jiang, Balrina Gupta, Eric Brodean, Kristin O'Neill, T Craig Seamans, John Bowers, Hao Chen
Bioreactor scale-up is a critical step in the production of therapeutic proteins such as monoclonal antibodies (MAbs). With the scale-up criterion such as similar power input per volume or O2 volumetric mass transfer coefficient (kL a), adequate oxygen supply and cell growth can be largely achieved. However, CO2 stripping in the growth phase is often inadequate. This could cascade down to increased base addition and osmolality, as well as residual lactate increase and compromised production and product quality...
April 25, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28439968/effects-of-an-ep2-and-ep3-receptor-dual-agonist-ono-8055-on-a-radical-hysterectomy-induced-underactive-bladder-model-in-monkeys
#15
Hidekazu Matsuya, Noritoshi Sekido, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada
OBJECTIVES: The objective was to develop an underactive bladder (UAB) model in primates and to evaluate the potential of prostanoid EP2 and EP3 receptor dual agonist ONO-8055 to become a therapeutic agent for UAB. METHODS: A surgical procedure resembling radical hysterectomy was performed on female cynomolgus monkeys. Subsequently, in vitro muscle strip studies were performed using bladder muscle strips from normal monkeys and monkeys that underwent surgery. In addition, uroflowmetric data were obtained at specified days after the surgery...
April 25, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28439381/psychometric-properties-of-an-arabic-safety-attitude-questionnaire-short-form-2006
#16
Aymen Elsous, Ali Akbarisari, Arash Rashidian, Yousef Aljeesh, Mahmoud Radwan, Hatem Abu Zaydeh
OBJECTIVES: There is a widespread interest in exploring healthcare providers' attitudes and perceptions about patient safety culture. This study was done to determine the reliability and validity of the Arabic version of Safety Attitude Questionnaire (SAQ) in Palestinian hospitals. METHODS: This was a methodological study and the SAQ was translated into Arabic using the forward-backward translation technique. Four Ministry of Health hospitals in the Gaza Strip were randomly selected, and proportionate systematic sampling was followed to select the participants...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28438283/effects-of-prenatal-music-stimulation-on-fetal-cardiac-state-newborn-anthropometric-measurements-and-vital-signs-of-pregnant-women-a-randomized-controlled-trial
#17
J García González, M I Ventura Miranda, F Manchon García, T I Pallarés Ruiz, M L Marin Gascón, M Requena Mullor, R Alarcón Rodriguez, T Parron Carreño
BACKGROUND: Music has been used for medicinal purposes throughout history due to its variety of physiological, psychological and social effects. OBJECTIVE: To identify the effects of prenatal music stimulation on the vital signs of pregnant women at full term, on the modification of fetal cardiac status during a fetal monitoring cardiotocograph, and on anthropometric measurements of newborns taken after birth. MATERIAL AND METHOD: A randomized controlled trial was implemented...
May 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28438012/smartphone-based-dual-modality-imaging-system-for-quantitative-detection-of-color-or-fluorescent-lateral-flow-immunochromatographic-strips
#18
Yafei Hou, Kan Wang, Kun Xiao, Weijian Qin, Wenting Lu, Wei Tao, Daxiang Cui
Nowadays, lateral flow immunochromatographic assays are increasingly popular as a diagnostic tool for point-of-care (POC) test based on their simplicity, specificity, and sensitivity. Hence, quantitative detection and pluralistic popular application are urgently needed in medical examination. In this study, a smartphone-based dual-modality imaging system was developed for quantitative detection of color or fluorescent lateral flow test strips, which can be operated anywhere at any time. In this system, the white and ultra-violet (UV) light of optical device was designed, which was tunable with different strips, and the Sobel operator algorithm was used in the software, which could enhance the identification ability to recognize the test area from the background boundary information...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28437953/high-power-cladding-light-stripper-using-segmented-corrosion-method-theoretical-and-experimental-studies
#19
Lu Yin, Mingjian Yan, Zhigang Han, Hailin Wang, Hua Shen, Rihong Zhu
We present the segmented corrosion method that uses hydrofluoric acid to etch the fiber of a fiber laser for removing high-power cladding light to improve stripping uniformity and power handling capability. For theoretical guidelines, we propose a simulation model of etched-fiber stripping to evaluate the relationship between the etched-fiber parameters and cladding light attenuation and to analyze the stripping uniformity achieved with segmented corrosion. A two-segment etched fiber is fabricated with cladding light attenuation of 19...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437942/optical-damage-resistant-ti-diffused-zr-er-codoped-lithium-niobate-strip-waveguide-for-high-power-980-nm-pumping
#20
Wen-Bao Sun, Xiao-Fei Yang, Zi-Bo Zhang, Wing-Han Wong, Dao-Yin Yu, Edwin Yue-Bun Pun, De-Long Zhang
Ti<sup>4+</sup>-diffused Zr<sup>4+</sup>/Er<sup>3+</sup>-codoped LiNbO<sub>3</sub> strip waveguide was fabricated on an X-cut LiNbO<sub>3</sub> substrate by thermal diffusion in sequence of Er<sup>3+</sup>, Zr<sup>4+</sup> and Ti<sup>4+</sup>. Secondary ion mass spectrometry study shows that the Ti<sup>4+</sup> ions follow a sum of two error functions in the width direction and a Gauss function in the depth direction of the waveguide...
April 17, 2017: Optics Express
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