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retinal artery occlusion

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https://www.readbyqxmd.com/read/28335564/passage-through-the-ocular-barriers-and-beneficial-effects-in-retinal-ischemia-of-topical-application-of-pacap1-38-in-rodents
#1
Dora Werling, William A Banks, Therese S Salameh, Timea Kvarik, Laszlo Akos Kovacs, Alexandra Vaczy, Edina Szabo, Flora Mayer, Rita Varga, Andrea Tamas, Gabor Toth, Zsolt Biro, Tamas Atlasz, Dora Reglodi
The neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) has two active forms, PACAP1-27 and PACAP1-38. Among the well-established actions are PACAP's neurotrophic and neuroprotective effects, which have also been proven in models of different retinopathies. The route of delivery is usually intravitreal in studies proving PACAP's retinoprotective effects. Recently, we have shown that PACAP1-27 delivered as eye drops in benzalkonium-chloride was able to cross the ocular barriers and exert retinoprotection in ischemia...
March 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28333850/multimodality-ocular-imaging-in-a-case-report-of-hyperviscosity-syndrome-associated-with-lymphoplasmacytic-leukemia-the-images-tell-the-story
#2
Rene Y Choi, Rachel Jacoby, Akbar Shakoor
PURPOSE: To report the clinical course of a patient with ocular manifestations of hyperviscosity syndrome associated with Waldenström macroglobulinemia, and for the first time, video imaging of mobile emboli in the conjunctival and retinal vasculature. METHODS AND PATIENT: A 60-year-old woman with newly diagnosed Waldenström macroglobulinemia, with no visual complaints was evaluated by the Ophthalmology service for a baseline ocular examination. RESULTS: At presentation, ocular examination revealed a visual acuity of 20/25 in each eye...
March 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28333176/efficacy-of-retrobulbar-hyaluronidase-injection-for-vision-loss-resulting-from-hyaluronic-acid-filler-embolization
#3
Guo-Zhang Zhu, Zhong-Sheng Sun, Wen-Xiong Liao, Bing Cai, Chun-Lin Chen, Hui-Hui Zheng, Li Zeng, Sheng-Kang Luo
Background: Vision loss is a rare but serious complication of facial hyaluronic acid (HA) filler injection, for which there is no proven rescue therapy. Retrobulbar hyaluronidase injection is advocated by many plastic surgeons as an emergency treatment, but has not been carefully assessed for its efficacy. Objectives: To evaluate the efficacy of retrobulbar hyaluronidase injection as a rescue treatment for vision loss caused by HA filler embolization. Methods: Patients with vision loss caused by HA filler embolization were treated with retrobulbar hyaluronidase injection...
January 20, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28330678/acute-macular-edema-and-peripapillary-soft-exudate-after-pancreas-transplantation-with-accelerated-progression-of-diabetic-retinopathy
#4
Fang-Yi Tsai, Ling-Ing Lau, An-Fei Li, Shih-Jen Chen, Shin-E Wang, Fenq-Lih Lee, Catherine Jiu-Lin Liu, Yi-Ming Shyr
BACKGROUND: The effect of pancreas transplantation on diabetic retinopathy remains inconclusive. Herein, we report six patients with type 1 diabetes mellitus (DM) who underwent pancreas transplantation and developed acute macular edema and peripapillary soft exudate with rapid progression to proliferative diabetic retinopathy. METHODS: In this retrospective observational study, diabetic patients who underwent pancreas transplantation in a single medical center and developed symptomatic acute macular edema and peripapillary soft exudate within 3 months after the operation were enrolled...
March 18, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28322870/painless-bilateral-visual-loss-in-a-33-year-old-woman-with-severe-arterial-hypotension
#5
Olaia Subirà, Silvia Muñoz, Juan José Sánchez, Paloma Puyalto, Andrew G Lee
A 32-year-old woman experienced dizziness and headache for 5 months. She also complained of painless, progressive bilateral visual loss for several weeks. Prior to developing the initial symptoms, she had an uncomplicated pregnancy except for dizziness and systemic hypotension during the first term. Fundus examination disclosed prominent retinal arteries, as well diffuse microaneurysms, widespread intraretinal hemorrhages, and hyperemic optic discs. Brain magnetic resonance imaging revealed multiple supratentorial white matter lesions suggestive of ischemic strokes...
March 16, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28298862/polycythemia-causing-posterior-segment-vascular-occlusions
#6
Suganeswari Ganesan, Rajiv Raman, Tarun Sharma
A 44-year-old male patient presented with features suggestive of transient central retinal artery occlusion (CRAO) followed by permanent CRAO and lateral posterior ciliary artery occlusion. He had diagnostic features of polycythemia vera (PV). When presented for the first time, the patient had features of ocular ischemia such as ocular pain, conjunctival congestion, and retinal opacification but with normal arm-to-retina time and normal arteriovenous transit time. During the second presentation, he had ocular pain, congested conjunctiva, retinal opacification, cherry red spot with box-carrying of retinal vessels, and choroidal infarct (Amalric's sign)...
January 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28295944/paracentral-acute-middle-maculopathy-as-a-finding-in-patients-with-severe-vision-loss-following-phacoemulsification-cataract-surgery
#7
Katarina Creese, Daini Ong, Sukhpal S Sandhu, David Ware, C Alex Harper, Salmaan H Al-Qureshi, Sanjeewa S Wickremasinghe
IMPORTANCE: Paracentral acute middle maculopathy (PAMM) as diagnosed by spectral domain optical coherence tomography (SD-OCT) may be associated with "patch off" visual loss post cataract surgery. BACKGROUND: To report a case series of severe vision loss due to PAMM after cataract surgery DESIGN: Retrospective case series. PARTICIPANTS: Cases from five surgical centres (public and private) in Victoria, Australia. METHODS: Retrospective analysis of cases with unexplained "patch-off" vision loss post cataract surgery...
March 13, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28281207/cilioretinal-artery-occlusion-and-anterior-ischemic-optic-neuropathy-as-the-initial-presentation-in-a-child-female-carrier-of-fabry-disease
#8
M Giray Ersoz, Gamze Ture
PURPOSE: To report the youngest female carrier of Fabry disease, complicated by cilioretinal artery occlusion and anterior ischemic optic neuropathy (AION). METHODS: Case report. RESULTS: An 11-year-old girl was referred to our clinic with painless, acute loss of vision in her right eye. Posterior segment examination and fluorescein angiography revealed cilioretinal artery occlusion and AION. Systemic evaluations were unremarkable, except for a low blood α-galactosidase A enzyme level of 242...
March 9, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28277067/platelet-activation-by-adp-is-increased-in-selected-patients-with-anterior-ischemic-optic-neuropathy-or-retinal-vein-occlusion
#9
Claudia Kuhli-Hattenbach, Peter Hellstern, Thomas Kohnen, Lars-Olof Hattenbach
To investigate whether adenosine diphosphate (ADP)-induced platelet hyperaggregability is associated with nonarteritic anterior ischemic optic neuropathy (NAION) or retinal vein occlusion (RVO). We retrospectively reviewed thrombophilia screening data of patients with NAION or RVO without a history of arterial hypertension, diabetes mellitus, hyperlipidemia, obesity, and cigarette abuse. Patients with a positive family history for thromboembolism were not excluded. Platelet aggregation (area under the curve, AUC) after induction of 0...
February 16, 2017: Platelets
https://www.readbyqxmd.com/read/28267111/blind-sided-by-cosmetic-vein-sclerotherapy-a-case-of-ophthalmic-arterial-occlusion
#10
Meena Arunakirinathan, Robbie J E Walker, Noor Hassan, Sally Ameen, Saad Younis
PURPOSE: Cosmetic vein sclerotherapy is increasingly used to treat varicose veins because of its effectiveness and adherence with British Pharmacopoeia specifications. We present the first documented case of ophthalmic artery occlusion resulting in panocular ischemia secondary to intravascular injection of sodium tetradecyl sulfate sclerosant in a young healthy women seeking treatment for prominent facial veins in her forehead. METHODS: The patient presented with unilateral sudden loss of vision...
March 6, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28258302/-ultrasound-biomicroscopy-in-giant-cell-arteritis
#11
M Pattmöller, L Daas, A Viestenz, G Milioti, A Hasenfus, B Seitz, A Viestenz
Giant cell arteritis may lead to irreversible blindness due to an anterior ischemic optic neuropathy or central retinal artery occlusion. Diagnosis of the giant cell arteritis is sometimes a problem: Difficulties may arise since a negative biopsy can not rule out the diagnosis. This case report demonstrates acute changes in the temporal artery as demonstrated by Ultrasound Biomicroscopy and documents its course during therapy with corticosteroids.
March 3, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28251087/retinal-vessel-oxygen-saturation-in-healthy-subjects-and-early-branch-retinal-vein-occlusion
#12
Jing-Yan Yang, Bing You, Qian Wang, Szy Yann Chan, Jost B Jonas, Wen-Bin Wei
AIM: To measure the retinal oxygen saturation in healthy subjects and early branch retinal vein occlusion (BRVO) in Chinese population. METHODS: The retinal vessel oxygen saturation of the healthy subjects and BRVO patients were measured by a noninvasive retinal oximeter (Oxymap ehf., Reykjavik, Iceland). RESULTS: The study included 22 patients with unilateral BRVO (mean age: 55.1±8.8y) in the study group and 91 healthy participants (mean age: 37...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28248916/light-induced-hemiplegia-an-atypical-case-of-retinal-steal-syndrome
#13
David Kerek, Sami Al Kasab, Michael U Antonucci, Raymond D Turner, Tanya N Turan
Atherosclerosis affecting the carotid arteries accounts for up to 20% of ischemic strokes 1. The clinical effects of atherosclerotic occlusive disease vary according to multiple factors, one of which is collateral circulation. In response to a chronic decrease in cerebral perfusion from atherosclerotic occlusion, alternative flow pathways, or collaterals, develop in a variety of patterns. In the setting of carotid occlusion, flow from the Circle of Willis, if complete, often comprises the main cerebral collateral network...
March 2017: Neurologist
https://www.readbyqxmd.com/read/28243029/central-retinal-artery-occlusion-by-left-atrial-myxoma
#14
Yong Tae Shin, Jong Ho Kim, Dong Ho Park, Jae Pil Shin, In Taek Kim
No abstract text is available yet for this article.
February 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28241312/changes-in-retinal-microcirculation-after-intravitreal-ranibizumab-injection-in-eyes-with-macular-edema-secondary-to-branch-retinal-vein-occlusion
#15
Marie Fukami, Takeshi Iwase, Kentaro Yamamoto, Hiroki Kaneko, Shunsuke Yasuda, Hiroko Terasaki
Purpose: To evaluate the effects of an intravitreal ranibizumab (IVR) injection on the retinal microcirculation of eyes with macular edema secondary to a branch retinal vein occlusion (BRVO). Methods: Twenty-six eyes of 26 patients with macular edema due to a BRVO that had received a single IVR injection (0.5 mg/0.05 mL) were studied. The retinal microcirculation was assessed by laser speckle flowgraphy (LSFG) using the mean blur rate (MBR) and relative flow volume (RFV)...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28239776/-erratum-to-retinal-artery-occlusion
#16
N Feltgen, A Pielen
No abstract text is available yet for this article.
February 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28237415/en-face-oct-analysis-to-assess-the-spectrum-of-perivenular-ischemia-and-paracentral-acute-middle-maculopathy-in-retinal-vein-occlusion
#17
Khalil Ghasemi Falavarjani, Nopasak Phasukkijwatana, K Bailey Freund, Emmett T Cunningham, Ananda Kalevar, H Richard McDonald, Rosa Dolz Marco, Philipp K Roberts, Irena Tsui, Richard Rosen, Lee Merrill Jampol, Srinivas R Sadda, David Sarraf
PURPOSE: To assess the spectrum of perivenular ischemia in eyes with retinal vascular obstruction (typically central or hemicentral retinal vein obstruction) using en face optical coherence tomography (OCT). DESIGN: Retrospective observational case series. METHODS: Eyes with recent retinal vascular occlusion illustrating paracentral acute middle maculopathy (PAMM) in a perivenular fern-like pattern with en face OCT were evaluated in this study...
February 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28228436/triamcinolone-emboli-leading-to-central-retinal-artery-occlusion-a-multimodal-imaging-study
#18
Nripen Gaur, Pallavi Singh, Rohan Chawla, Brijesh Takkar
A 19-year-old man presented with unilateral sudden onset vision loss following an intra-articular triamcinolone injection in the right temporomandibular joint. At fundus examination emboli of triamcinolone were visible in multiple retinal arteries. Choroidal ischaemia and occlusion of the central retinal artery and its branches were documented at fluorescein angiography. Optical coherence tomography revealed significant thickening of the inner retinal layers. Optical coherence tomography angiography clearly demonstrated an abrupt cut-off of flow in a vessel below the optic disc...
February 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28195622/optical-coherence-tomography-angiography-of-paracentral-acute-middle-maculopathy-associated-with-primary-antiphospholipid-syndrome
#19
Matthew G J Trese, Aristomenis Thanos, Yoshihiro Yonekawa, Sandeep Randhawa
The authors present the first case of paracentral acute middle maculopathy as a manifestation of primary antiphospholipid syndrome (APS) with multimodal imaging, including optical coherence tomography angiography (OCTA). The association between APS and ophthalmic sequela is well-known. Recent advances in multimodal imaging, specifically OCTA, allow for better characterization of the mechanism and extent by which retinal arterial thrombosis can cause vision loss. Using advanced imaging modalities, the authors provide a comprehensive assessment of retinal ischemia, which showed not only localized capillary occlusion, but also ischemia of the deep retinal capillary plexus...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28184347/intra-arterial-thrombolysis-for-central-retinal-artery-occlusion-after-the-coil-embolization-of-paraclinoid-aneurysm
#20
Minwook Yoo, Sung-Chul Jin, Hae Yu Kim, Byeong-Sam Choi
The most common complication of coil embolization for cerebral aneurysms is thrombo-embolic stroke; in rare cases, these strokes, can present with central retinal artery occlusion. At our institution, a 53-year-old woman underwent stent-assisted coiling of the aneurysm. The patient's vision was improved immediately after intra-arterial thrombolysis and had further improved 8 months later. This report describes our experience of a rare case of central retinal artery occlusion after coil embolization that was successfully treated by intra-arterial thrombolysis...
December 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
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