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https://www.readbyqxmd.com/read/29450378/ocular-posterior-pole-pathological-modifications-related-to-complicated-pregnancy-a-review
#1
REVIEW
Vanessa Andrada Păun, Zamfir-Radu Ionescu, Liliana Voinea, Monica Cîrstoiu, Alexandru Baroș, Ștefan Pricopie, Radu Ciuluvică
Ocular posterior pole modification are a pathological manifestation in complicated pregnancies, especially when pregnancy induced hypertension is present (PIH), as well as in preeclampsia (PE) or eclampsia. Nonetheless, as the pregnancy evolves, the possibility for an aggravated evolution with HELLP syndrome, disseminated intravascular coagulation, and idiopathic thrombocytopenic purpura may have an ocular manifestation that, mainly, implies a loss of visual field or acuity, that, left unattended, may constitute a permanent impairment...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29449066/characteristics-of-headache-in-relation-to-the-manifestation-of-susac-syndrome
#2
Diana Obelienienė, Raminta Macaitytė, Renata Balnytė, Rūta Pėstininkaitė, Rymantė Gleiznienė, Jūratė Balčiūnienė
Susac syndrome is characterized by a clinical triad of encephalopathy, branch retinal artery occlusion, and hearing loss. Due to the absence of the whole complex of the triad in the majority of cases at disease presentation, the syndrome often remains underdiagnosed and untreated. Headache is estimated to affect up to 80% of Susac syndrome patients, but the relevance of headache characteristics and profile is not yet clear. The proposed diagnostic criteria of the European Susac Consortium acknowledge headache as a possible brain manifestation if it is new, described as migrainous or oppressive, and precedes the other symptoms by not more than 6 months...
February 3, 2018: Medicina
https://www.readbyqxmd.com/read/29439995/primary-photodynamic-therapy-with-verteporfin-for-pigmented-posterior-pole-ct1a-choroidal-melanoma-a-3-year-retrospective-analysis
#3
Ido Didi Fabian, Andrew W Stacey, Lamis Al Harby, Amit K Arora, Mandeep S Sagoo, Victoria M L Cohen
AIMS: To investigate the outcomes of primary photodynamic therapy (PDT) for pigmented posterior pole cT1a choroidal melanoma. METHODS: Retrospective interventional consecutive case series of 26 patients (26 eyes) with pigmented posterior pole cT1a choroidal melanoma, who were treated with 3 sessions of PDT and followed-up thereafter. RESULTS: Included were 11 males and 15 females that presented at a median age of 66 years (mean: 64) with transformed naevi (n=11) or suspicious lesions (n=15) with ≥3 risk factors for growth, with lipofuscin in all...
February 13, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29423458/posterior-ciliary-artery-occlusion
#4
Sohan Singh Hayreh
Objective: To compare the severity of ischemic damage following posterior ciliary artery (PCA) occlusion in old, atherosclerotic, hypertensive monkeys to that in young monkeys. Design: Experimental study. Subjects: Seven eyes of normal, healthy rhesus monkeys and 8 of old, atherosclerotic, hypertensive monkeys. Methods: By lateral orbitotomy, all PCAs were cut behind the eyeball in both groups of animals. The fundus and the optic disc were evaluated by repeated ophthalmoscopy, color fundus photography and fluorescein fundus angiography, before and immediately after cutting the PCAs and serially thereafter during the follow-up period...
February 2018: Ophthalmology Retina
https://www.readbyqxmd.com/read/29403595/visibility-of-blood-flow-on-optical-coherence-tomography-angiography-in-a-case-of-branch-retinal-artery-occlusion
#5
Sophie Bonnin, Valérie Krivosic, Emmanuel Cognat, Ramin Tadayoni
Purpose: We report the variability in flow angiogram during the course of branch retinal artery occlusion (BRAO) in a case imaged by optical coherence tomography angiography (OCTA). Case Report: OCTA was performed in a patient with BRAO at initial examination and 6 hours later. Initially, the occluded retinal artery and its branches were not detected on OCTA whereas a slow perfusion was present on fluorescein angiography. Six hours after initial examination, flow was detected on OCTA image in the previously occluded artery...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29403592/management-of-retinal-diseases-in-pregnant-patients
#6
REVIEW
Julie M Rosenthal, Mark W Johnson
Pregnancy leads to significant changes in the body, which potentially affect the retina. Pregnancy can induce disease, such as that seen in hypertensive retinopathy and choroidopathy. It can cause exudative retinal detachments in the HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), disseminated intravascular coagulation (DIC), and thrombotic thrombocytopenic purpura (TTP), and provoke arterial and venous retinal occlusive disease. Pregnancy may also exacerbate pre-existing retinal disease, such as idiopathic central serous chorioretinopathy (ICSC) and diabetic retinopathy...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29393247/optical-coherence-tomography-based-angiography-in-retinal-artery-occlusion-in-children
#7
Wojciech Hautz, Joanna Gołębiewska, Agnieszka Czeszyk-Piotrowicz
PURPOSE: To evaluate the role of optical coherence tomography (OCT)-based angiography (OCTA) in the diagnosis and monitoring of pediatric patients with retinal artery occlusion (RAO). MATERIAL AND METHODS: This retrospective study was conducted at the Department of Ophthalmology, The Children's Memorial Health Institute, in Warsaw between March 2015 and May 2016. Every patient underwent a complete ophthalmological examination. The diagnosis of the disease was based on fundus examination and fluorescein angiography (FA)...
January 24, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29380798/bilateral-arterial-occlusions-masking-retinitis-in-a-hiv-positive-male
#8
Kalpana Babu, Bhagya Sudheer, Krishna R Murthy
We report an interesting case of 36-year-old HIV-positive male with uveitis, cilioretinal artery occlusion in OD, and superotemporal branch retinal artery occlusion in OS. Hypercoagulability, cardiovascular, and rheumatologic workups were unremarkable. Aqueous taps were negative for toxoplasma, viruses, and MTb by multiplex polymerase chain reaction. Patches of retinitis were seen on clearing of retinal edema. Serology was positive for toxoplasma and rickettsia. Management included doxycycline, azithromycin, bactrim DS, and oral steroids...
February 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29378380/intra-arterial-thrombolytic-therapy-is-not-a-therapeutic-option-for-filler-related-central-retinal-artery-occlusion
#9
Yi-Chun Chen, Hsiu-Mei Wu, Shin-Jen Chen, Han-Jui Lee, Jiing-Feng Lirng, Chung-Jung Lin, Feng-Chi Chang, Chao-Bao Luo, Wan-Yuo Guo
Cosmetic facial filler-related central retinal artery occlusion (CRAO) is a devastating complication of facial hyaluronic acid (HA) injection and can be managed by intra-arterial thrombolytic therapy (IATT). The authors report on a 20-year-old woman who developed unilateral CRAO due to facial HA injection and who, despite prompt IATT, lost vision. A review of the related literature found 14 other female patients who developed cosmetic facial filler-related CRAO and accepted IATT management. In no case was vision loss clinically improved...
January 29, 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29370018/differentiating-occult-branch-retinal-artery-occlusion-from-primary-open-angle-glaucoma
#10
Michael Sullivan-Mee, Pathik Amin, Denise Pensyl, Suchitra Katiyar
SIGNIFICANCE: Clinical findings in occult branch retinal artery occlusion (BRAO) can mimic those of primary open-angle glaucoma (POAG). Because management of these conditions substantially differs, accurate diagnosis is crucial. Our comparative analysis indicates that specific macular thickness variables reliably differentiate these conditions and that macular scanning may enhance routine glaucoma evaluation. PURPOSE: The aim of this study was to identify clinical factors that reliably and efficiently identify occult BRAO masquerading as POAG...
January 25, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29369960/risk-of-acute-ischemic-stroke-in-patients-with-monocular-vision-loss-of-vascular-etiology
#11
Lucy Y Zhang, Jason Zhang, Richard K Kim, Jared L Matthews, Danielle S Rudich, David M Greer, Robert L Lesser, Hardik Amin
BACKGROUND: To evaluate the risk of concurrent acute ischemic stroke and monocular vision loss (MVL) of vascular etiology. DESIGN: Retrospective, cross-sectional study. SUBJECTS: Patients aged 18 or older diagnosed with MVL of suspected or confirmed vascular etiology who had no other neurologic deficits and who received brain MRI within 7 days of onset of visual symptoms were included. METHODS: A medical record review was performed from 2013 to 2016 at Yale New Haven Hospital...
January 22, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29368001/pharmacokinetics-tissue-localization-toxicity-and-treatment-efficacy-in-the-first-small-animal-rabbit-model-of-intra-arterial-chemotherapy-for-retinoblastoma
#12
Anthony B Daniels, Michael T Froehler, Janene M Pierce, Amy H Nunnally, M Wade Calcutt, Thomas M Bridges, David C LaNeve, Phillip E Williams, Kelli L Boyd, Michelle L Reyzer, Craig W Lindsley, Debra L Friedman, Ann Richmond
Purpose: Current intra-arterial chemotherapy (IAC) drug regimens for retinoblastoma have ocular and vascular toxicities. No small-animal model of IAC exists to test drug efficacy and toxicity in vivo for IAC drug discovery. The purpose of this study was to develop a small-animal model of IAC and to analyze the ocular tissue penetration, distribution, pharmacokinetics, and treatment efficacy. Methods: Following selective ophthalmic artery (OA) catheterization, melphalan (0...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29366614/correlation-between-ischemic-index-of-retinal-vein-occlusion-and-oxygen-saturation-in-retinal-vessels
#13
Irena Šínová, Jiří Řehák, Jana Nekolová, Naďa Jirasková, Petra Haluzová, Tereza Řeháková, Barbora Babková, Libor Hejsek, Martin Šín
PURPOSE: The aim of this study was to evaluate the relationship between the ischemic index and the oxygen saturation in retinal vessels in patients with retinal vein occlusion. DESIGN: Prospective, cross-sectional study. METHODS: We performed a prospective study. The cohort consisted of 43 eyes of 43patients with retinal vein occlusions (RVO), 23 of whom had central retinal vein occlusions (CRVO) and 20 who had branch retinal vein occlusions (BRVO)...
January 20, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29360684/thrombus-in-lamina-cribrosa-seen-using-swept-source-optical-coherence-tomography-in-eye-with-central-retinal-artery-occlusion
#14
Hisayoshi Satoh, Maiko Maruyama-Inoue, Shimpei Sato, Shin Yamane, Kazuaki Kadonosono
No abstract text is available yet for this article.
January 19, 2018: Retina
https://www.readbyqxmd.com/read/29358594/intra-retinal-arterial-cannulation-using-a-microneedle-for-central-retinal-artery-occlusion
#15
Kazuaki Kadonosono, Shin Yamane, Maiko Inoue, Tadashi Yamakawa, Eiichi Uchio
Central retinal artery occlusion (CRAO) is a severe disease, often causing blindness. We evaluated the efficacy and safety of a surgical procedure for the treatment of acute CRAO in which retinal arterial cannulation with tissue plasminogen activator (tPA) is performed. The surgical procedure consisted of vitrectomy followed by cannulation of the central retinal artery and injection of tPA (200 μg) using a 47-gauge microneedle. Thirteen CRAO patients were treated within 48 hours of the onset of symptoms...
January 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29358510/ophthalmic-artery-mri-in-an-arteritis-related-central-retinal-artery-occlusion
#16
David Weisenburger-Lile, Michael Obadia, Armelle Cahuzac, Augustin Lecler
No abstract text is available yet for this article.
January 23, 2018: Neurology
https://www.readbyqxmd.com/read/29341996/retinal-arterio-arterial-collaterals-in-susac-syndrome
#17
Robert A Egan, Guy Jirawuthiworavong, Norah S Lincoff, John J Chen, Courtney E Francis, Jacqueline A Leavitt
BACKGROUND: The ophthalmic findings of Susac syndrome (SS) consist of visual field defects related to branch retinal artery occlusion (BRAO), and fluorescein angiography (FA) reveals a unique staining pattern. To date, retinal arterial collateral development has been described only in a single patient. Given that the immunopathological process in SS induces retinal ischemia, it is conceivable that abnormal blood vessel development may occur in affected individuals. METHODS: This is a retrospective observational study...
January 16, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29330062/fundus-densitometry-findings-suggest-optic-disc-hemorrhages-in-primary-open-angle-glaucoma-have-an-arterial-origin
#18
Jonathan C Chou, Clara C Cousins, John B Miller, Brian J Song, Lucy Q Shen, Michael A Kass, Janey L Wiggs, Louis R Pasquale
PURPOSE: To analyze optic disc hemorrhages (DH) associated with primary open-angle glaucoma by quantifying their geometric profile and comparing their densitometry with hemorrhages from retinal vein occlusions (RVO) and retinal macroaneurysms (MA), which have venous and arterial sources of bleeding, respectively. DESIGN: Retrospective cross-sectional study METHODS: Setting: Massachusetts Eye & Ear POPULATION: Fundus images of DH (n=40), MA (n=14), and RVO (n=25) were identified...
January 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29323754/a-rare-cause-of-retinal-artery-embolism-accessory-mitral-valve-tissue
#19
Muzaffer Kahyaoglu, Arzu Kalayci, Cetin Gecmen, Munevver Sari, Ahmet Guner, Mehmet Celik, Ibrahim Akin İzgi, Cevat Kirma
A 42-year-old female patient was referred our clinic for investigation of a history of acute retinal artery occlusion. Transthoracic echocardiography showed a cyst-like, mobile formation on posterior mitral valve leaflet. 2D and real time 3D transesophageal echocardiography showed a flexible circular mobile structure which was attached to posterior mitral valve leaflet. Echocardiographic appearance and morphological characteristics were suggestive of accessory mitral valve tissue.
February 2018: Echocardiography
https://www.readbyqxmd.com/read/29317400/two-year-outcomes-of-intravitreal-ziv-aflibercept
#20
Ahmad M Mansour, Mohammed Ashraf, Abdulrazzak Charbaji, Muhammad H Younis, Ahmed A Souka, Avantika Dogra, Hana A Mansour, Jay Chhablani
AIM: To assess the two-year outcome of intravitreal ziv-aflibercept (IVZ) in eyes with macular diseases. METHODS: Consecutive subjects with various macular diseases that received six or more of 0.05 mL IVZ (1.25 mg) injections with at least 1 year follow-up were included. Outcome measures were best-corrected visual acuity (BCVA) (logarithm of the minimum angle of resolution) and central macular thickness (CMT) on spectral domain optical coherence tomography...
January 9, 2018: British Journal of Ophthalmology
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