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https://www.readbyqxmd.com/read/29326505/influence-of-intracanal-irrigants-on-coronal-fracture-resistance-of-endodontically-treated-and-bleached-teeth-an-in-vitro-study
#1
Maryam Khoroushi, Fatemeh Tavakol, Farinaz Shirban, Sanaz Ziaei
Background: Irrigation has a key role in the success of endodontic treatment. Intracanal irrigant solutions have adverse effects on the physical properties of dentin. Aim: The present study aimed to evaluate the effect of different irrigation protocols on coronal fracture resistance of endodontically treated teeth undergoing bleaching treatment. Design and Materials and Methods: Access cavities were prepared in 120 maxillary premolars which were divided into two groups (n = 60) - Group A: nonbleached, Group B: bleached (B)...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29313768/from-longshot-to-fantasy-obligations-to-pediatric-patients-and-families-when-last-ditch-medical-efforts-fail
#2
Elliott Mark Weiss, Autumn Fiester
Clinicians at quaternary centers see part of their mission as providing hope when others cannot. They tend to see sicker patients with more complex disease processes. Part of this mission is offering longshot treatment modalities that are unlikely to achieve their stated goal, but conceivably could. When patients embark on such a treatment plan, it may fail. Often treatment toward an initial goal continues beyond the point at which such a goal is feasible. We explore the progression of care from longshot to fantasy using two pediatric cases...
January 2018: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/29284107/assessing-the-appearance-and-fluorescence-of-resin-infiltrated-white-spot-lesions-with-caries-detection-devices
#3
K Markowitz, K Carey
OBJECTIVE: This in vitro study examined the effectiveness of caries detector devices in assessing the ability of resin infiltration (RI) (Icon, DMG-Hamburg, Hamburg, Germany) to improve the optical properties of enamel white spot lesions (WSLs). METHODS AND MATERIALS: Ten caries-free third molars were used. Photographs, a subjective visual assessment of the photographs, fluorescent camera (FC) images using the Spectra (Air Techniques, Melville, NY, USA), and laser fluorescent (LF) readings using the DIAGNOdent (KaVo, Biberach, Germany) were obtained from each tooth's buccal surface...
January 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29281957/when-honesty-and-cheating-pay-off-the-evolution-of-honest-and-dishonest-equilibria-in-a-conventional-signalling-game
#4
Szabolcs Számadó
BACKGROUND: The reliability of signals is a key issue in the study of animal communication. Both empirical work and theoretical models show that communication need not be entirely honest, and thus signals can be deceitful. Aggressive communication appears to be a prime candidate for such deceitful communication, because bluffing has been described in several species. Bluffing in these situations are supposed to be maintained by frequency dependent selection where the fitness of a given type depends on the frequencies of the other types in the population...
December 28, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/29250848/informal-caregivers-views-on-the-division-of-responsibilities-between-themselves-and-professionals-a-scoping-review
#5
REVIEW
Yvette Wittenberg, Rick Kwekkeboom, Janneke Staaks, Arnoud Verhoeff, Alice de Boer
This scoping review focuses on the views of informal caregivers regarding the division of care responsibilities between citizens, governments and professionals and the question of to what extent professionals take these views into account during collaboration with them. In Europe, the normative discourse on informal care has changed. Retreating governments and decreasing residential care increase the need to enhance the collaboration between informal caregivers and professionals. Professionals are assumed to adequately address the needs and wishes of informal caregivers, but little is known about informal caregivers' views on the division of care responsibilities...
December 18, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29233607/the-concept-of-frailty-in-intensive-care
#6
Fakhri Athari, Ken M Hillman, Steven A Frost
Our population is ageing and this is also reflected in the ageing of the hospital and intensive care population. Along with ageing, there is also an increase in age-related chronic health conditions or co-morbidities, which in turn affects the patient's functional state. There is an increasing need to describe a patient's clinical condition in terms of their functional capacity, such as frailty. Frailty is an age-related syndrome which reduces physiological and cognitive reserves. As a result, frailty increases people's vulnerability to insults such as infection and trauma...
December 9, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29228788/understanding-the-experiences-of-middle-school-girls-who-have-received-help-for-non-suicidal-self-injury
#7
Kathleen S Tillman, Michael Prazak, Megan L Obert
This study aimed to understand the experiences of middle school girls who have engaged in non-suicidal self-injury (NSSI) and have received professional help for these behaviors. Participants described engaging in NSSI in response to uncomfortable feelings and invasive negative thoughts. They reported that engaging in NSSI decreased their uncomfortable feelings. While each participant had at least one person in her life who knew about her NSSI, participants did not feel supported or validated by these people...
December 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29227124/the-effects-of-symptom-information-coaching-on-the-feigning-of-adult-adhd
#8
Maryanne Edmundson, David T R Berry, Hannah L Combs, Stacey L Brothers, Jordan P Harp, Ande Williams, Stephanie L Rojas, Ahmed K Saleh, April B Scott
College students without ADHD may feign symptoms of ADHD to gain access to stimulant medications and academic accommodations. Unfortunately, research has shown that it can be difficult to discriminate malingered from genuine ADHD symptomatology, especially when evaluations are based only on self-report questionnaires. The present study investigated whether nonclinical college students given no additional information could feign ADHD as successfully as those who were coached on symptoms of the disorder. Similar to Jasinski et al...
December 2017: Psychological Assessment
https://www.readbyqxmd.com/read/29220400/social-structure-opportunistic-punishment-and-the-evolution-of-honest-signaling
#9
Robin Clark, Steven O Kimbrough
Honest signaling is generally taken to be a necessary pre-condition for a stable signaling system, because deceptive signaling at a high enough rate should cause receivers to ignore the signal, which in turn undermines the utility of sending signals. Deception is normally thought to occur because of benefits it has to the deceiver. This raises the question of why signaling systems should exist and persist over time, especially in cases in which the interests of the senders and receivers are not well aligned...
2017: PloS One
https://www.readbyqxmd.com/read/29211513/facilitators-and-barriers-to-pre-exposure-prophylaxis-willingness-among-young-men-who-have-sex-with-men-who-use-geosocial-networking-applications-in-california
#10
Ian W Holloway, Diane Tan, Jennifer L Gildner, Sean C Beougher, Craig Pulsipher, Jorge A Montoya, Aaron Plant, Arleen Leibowitz
While correlates of pre-exposure prophylaxis (PrEP) uptake have been explored among older men who have sex with men (MSM), less is known about the facilitators and barriers that encourage uptake among younger MSM (YMSM). This study explores the association between willingness to take PrEP and demographic characteristics, sexual risk, and substance use, and attitudinal factors among YMSM in California who use geosocial networking applications (GSN apps). Based on survey data from YMSM recruited through GSN apps (n = 687), PrEP willingness was positively associated with Hispanic ethnicity [adjusted odds ratio (aOR): 1...
December 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/29195112/promoting-honesty-in-young-children-through-observational-learning
#11
Fengling Ma, Gail D Heyman, Chunyan Jing, Ying Fu, Brian J Compton, Fen Xu, Kang Lee
The observational learning approach, developed more than a half century ago, suggests that it is possible to promote desirable social behaviors through peer observation. However, this idea has yet to be put to a rigorous empirical test. The current research sought to fill this gap by examining whether honesty can be promoted in children by allowing them to observe a peer's display of honest behavior. The dependent measure was whether 5-year-old children who had cheated by peeking in a guessing game would confess to it...
March 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29186919/a-strategic-bargaining-game-for-a-spectrum-sharing-scheme-in-cognitive-radio-based-heterogeneous-wireless-sensor-networks
#12
Yuxing Mao, Tao Cheng, Huiyuan Zhao, Na Shen
In Wireless Sensor Networks (WSNs), unlicensed users, that is, sensor nodes, have excessively exploited the unlicensed radio spectrum. Through Cognitive Radio (CR), licensed radio spectra, which are owned by licensed users, can be partly or entirely shared with unlicensed users. This paper proposes a strategic bargaining spectrum-sharing scheme, considering a CR-based heterogeneous WSN (HWSN). The sensors of HWSNs are discrepant and exist in different wireless environments, which leads to various signal-to-noise ratios (SNRs) for the same or different licensed users...
November 27, 2017: Sensors
https://www.readbyqxmd.com/read/29178533/urethral-complications-after-transgender-phalloplasty-and-strategies-to-treat-them-and-minimize-their-occurrence
#13
REVIEW
Richard A Santucci
BACKGROUND: Radial forearm free flap phalloplasty (RFFP) is the current standard of care for most FTM gender confirmation surgeries. This procedure is associated with a rate of urethral stricture as high as 51%, which falls only to 23-35% even among the most experienced contemporary surgeons. While some modifications have been proposed to combat this high complication rate, it still remains a major source of lasting morbidity. METHODS: Literature review of RFFP literature...
November 27, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29177843/stabilising-selection-on-immune-response-in-male-black-grouse-lyrurus-tetrix
#14
Carl D Soulsbury, Heli Siitari, Christophe Lebigre
Illnesses caused by a variety of micro- and macro- organisms can negatively affect individuals' fitness, leading to the expectation that immunity is under positive selection. However, immune responses are costly and individuals must trade-off their immune response with other fitness components (e.g. survival or reproductive success) meaning that individuals with intermediate response may have the greatest overall fitness. Such a process might be particularly acute in species with strong sexual selection because the condition-dependence of male secondary sexual-traits might lead to striking phenotypic differences amongst males of different immune response levels...
November 24, 2017: Oecologia
https://www.readbyqxmd.com/read/29158373/revisiting-expectations-in-an-era-of-precision-oncology
#15
Emily J Marchiano, Andrew C Birkeland, Paul L Swiecicki, Kayte Spector-Bagdady, Andrew G Shuman
As we enter an era of precision medicine and targeted therapies in the treatment of metastatic cancer, we face new challenges for patients and providers alike as we establish clear guidelines, regulations, and strategies for implementation. At the crux of this challenge is the fact that patients with advanced cancer may have disproportionate expectations of personal benefit when participating in clinical trials designed to generate generalizable knowledge. Patient and physician goals of treatment may not align, and reconciliation of their disparate perceptions must be addressed...
November 20, 2017: Oncologist
https://www.readbyqxmd.com/read/29140563/-stink-flirting-in-ring-tailed-lemurs-lemur-catta-male-olfactory-displays-to-females-as-honest-costly-signals
#16
Amber D Walker-Bolton, Joyce A Parga
Sexual selection for honest behavioral displays of quality has driven the development of remarkably complex courtship behavior in many animal species. Olfactory displays are often overlooked as an area of inquiry compared to auditory and visual displays. Ring-tailed lemur (Lemur catta) scent marking of substrates has been studied extensively, although the male olfactory displays of anointing and wafting tails to females has received relatively little attention. We studied the role of male olfactory displays to females, evaluating whether such signals function as honest, costly signals of male dominance status in two groups of wild L...
November 15, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29135993/bioequivalence-between-innovator-and-generic-tacrolimus-in-liver-and-kidney-transplant-recipients-a-randomized-crossover-clinical-trial
#17
Rita R Alloway, Alexander A Vinks, Tsuyoshi Fukuda, Tomoyuki Mizuno, Eileen C King, Yuanshu Zou, Wenlei Jiang, E Steve Woodle, Simon Tremblay, Jelena Klawitter, Jost Klawitter, Uwe Christians
BACKGROUND: Although the generic drug approval process has a long-term successful track record, concerns remain for approval of narrow therapeutic index generic immunosuppressants, such as tacrolimus, in transplant recipients. Several professional transplant societies and publications have generated skepticism of the generic approval process. Three major areas of concern are that the pharmacokinetic properties of generic products and the innovator (that is, "brand") product in healthy volunteers may not reflect those in transplant recipients, bioequivalence between generic and innovator may not ensure bioequivalence between generics, and high-risk patients may have specific bioequivalence concerns...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29120314/ethical-challenges-in-fasd-prevention-scientific-uncertainty-stigma-and-respect-for-women-s-autonomy
#18
Natalie Zizzo, Eric Racine
Fetal alcohol spectrum disorder (FASD) is a leading form of neurodevelopmental delay in Canada, affecting an estimated 3000 babies per year. FASD involves a range of disabilities that entail significant costs to affected individuals, families, and society. Exposure to alcohol in utero is a necessary factor for FASD development, and this has led to FASD being described as "completely preventable". However, there are significant ethical challenges associated with FASD prevention. These challenges revolve around 1) what should be communicated about the risks of alcohol consumption during pregnancy, given some ongoing scientific uncertainty about the effects of prenatal alcohol exposure, and 2) how to communicate these risks, given the potential for stigma against women who give birth to children with FASD as well as against children and adults with FASD...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29115752/aide-memoire-diaries-in-longitudinal-research
#19
Sara Helen Denham, Ruth Taylor, Tracey Humphrey
BACKGROUND: Diaries can be used as contemporaneous tools for gathering data, frequently in combination with interviews. However, diaries can also be used by study participants as personal records to improve their recall during interviews, without having to be collected for analysis. AIM: To discuss the use of diaries as aide-memoires by participants in a study exploring women's views and experiences of the quality of maternity care they received in community maternity units in Scotland...
September 19, 2017: Nurse Researcher
https://www.readbyqxmd.com/read/29115603/amelioration-of-lung-ischemia%C3%A2-reperfusion-injury-by-jnk-and-p38-small-interfering-rnas-in-rat-pulmonary-microvascular-endothelial-cells-in-an-ischemia%C3%A2-reperfusion-injury-lung-transplantation-model
#20
Juan Wang, Jing Tan, Yanhong Liu, Linlin Song, Di Li, Xiaoguang Cui
The inhibition of mitogen‑activated protein kinases (MAPKs), including c‑Jun NH2‑terminal protein kinase (JNK), p38 MAPK (p38) and extracellular signal‑regulated protein kinase 1/2 (ERK1/2), have an important effect on lung ischemia‑reperfusion injury (IRI) during lung transplantation (LT). However, the way in which combined MAPK inhibition exerts optimal protective effects on lung IRI remains to be elucidated. Therefore, the present study evaluated the therapeutic efficacy of the inhibition of MAPKs in rat pulmonary microvascular endothelial cells (PMVECs) in an IRI model of LT...
November 6, 2017: Molecular Medicine Reports
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