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Cancer surgery

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https://www.readbyqxmd.com/read/29457355/visceral-obesity-is-a-significant-risk-factor-for-incisional-hernia-after-laparoscopic-colorectal-surgery-a-single-center-review
#1
Masateru Yamamoto, Yuji Takakura, Satoshi Ikeda, Toshiyuki Itamoto, Takashi Urushihara, Hiroyuki Egi
INTRODUCTION: Although laparoscopic surgery uses relatively small incisions, incisional hernia after surgery is not uncommon. However, the incidence of incisional hernia and its risk factors are not well known. The purpose of our study was to investigate risk factors for incisional hernia after laparoscopic colorectal cancer surgery. METHODS: The study group consisted of 212 patients who underwent laparoscopic colorectal cancer surgery at Hiroshima Prefectural Hospital between November 2008 and October 2013...
February 19, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29457215/the-effect-of-anaesthetic-technique-during-primary-breast-cancer-surgery-on-neutrophil-lymphocyte-ratio-platelet-lymphocyte-ratio-and-return-to-intended-oncological-therapy
#2
A Ní Eochagáin, D Burns, B Riedel, D I Sessler, D J Buggy
Inflammation and immunosuppression contribute to the pathogenesis of cancer. An increased neutrophil-lymphocyte ratio reflects these processes and is associated with adverse cancer outcomes. Whether anaesthetic technique for breast cancer surgery influences these factors, and potentially cancer recurrence, remains unknown. We conducted a secondary analysis in patients enrolled in an ongoing trial of anaesthetic technique on breast cancer recurrence. The primary hypothesis was that postoperative neutrophil-lymphocyte ratio is lower in patients allocated to receive propofol-paravertebral rather than inhalational agent-opioid anaesthesia for primary breast cancer surgery...
February 19, 2018: Anaesthesia
https://www.readbyqxmd.com/read/29456850/-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-the-prediction-of-survival-in-patients-with-advanced-esophageal-cancer-who-have-undergone-neoadjuvant-chemotherapy
#3
Masahiko Yano, Hiroshi Miyata, Keijiro Sugimura, Masaaki Motoori, Takeshi Omori, Yoshiyuki Fujiwara, Norikatsu Miyoshi, Masayoshi Yasui, Masayuki Ohue, Hirofumi Akita, Akira Tomokuni, Hidenori Takahashi, Shogo Kobayashi, Masato Sakon
Neoadjuvant chemotherapy (NAC) is a promising treatment strategy for advanced esophageal cancer. However, measures of NAC response assessment and prognostic prediction have not yet been established. The aim of this study was to evaluate the usefulness of combined18 F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT). A total of 77 patients with stage IB-IV esophageal cancer who were treated with NAC followed by curative resection were retrospectively analyzed. PET/CT was performed before and after NAC and 56 patients were clinical responders...
March 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29456731/analysis-of-middle-and-long-term-efficacy-of-thoracoscope-assisted-segmental-resection-of-the-lung-on-non-small-cell-lung-cancer-in-the-early-stage
#4
Ning Ding, Ning Zhou, Qinglin Li, Guangming Ren, Min Zhou
We investigated the short- and long-term efficacy of thoracoscope-assisted segmental resection of lung of non-small cell lung cancer (NSCLC). We selected a total of 94 patients with lung cancer in the early stage who were admitted to The First People's Hospital of Xuzhou for treatment between March 2011 and February 2012. Patients were divided randomly into either the control group (n=47) or the observation group (n=47). In the observation group, patients received thoracoscope-assisted segmental resection of lung, while in the control group, the conventional thoracic surgery was performed for treatment...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29456726/association-of-histone-deacetylase-expression-with-histology-and-prognosis-of-ovarian-cancer
#5
Mitsutake Yano, Masanori Yasuda, Mika Sakaki, Koji Nagata, Takashi Fujino, Eiichi Arai, Takahiro Hasebe, Masaki Miyazawa, Mariko Miyazawa, Naoki Ogane, Kosei Hasegawa, Hisashi Narahara
Histone deacetylase (HDAC) inhibitor is known to have a cytotoxic effect on ovarian cancer cell lines. The present study analyzed the association between immunohistochemical HDAC expression and clinicopathological findings, in particular, the association with histological type and effect of chemotherapy. The histology of the 201 ovarian cancers addressed was as follows: Serous carcinoma (SEC), 100 cases; clear cell carcinoma (CCC), 56 cases; endometrioid carcinoma (EMC), 36 cases; and mucinous carcinoma (MUC), 9 cases...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29456472/electron-beam-intraoperative-radiotherapy-eliot-in-pregnant-women-with-breast-cancer-from-in-vivo-dosimetry-to-clinical-practice
#6
Maria Leonardi, Agnese Cecconi, Rosa Luraschi, Elena Rondi, Federica Cattani, Roberta Lazzari, Anna Morra, Santos Soto, Vanna Zanagnolo, Viviana Galimberti, Oreste Gentilini, Fedro Peccatori, Barbara Jereczek-Fossa, Roberto Orecchia
Background: The aim of this study was to confirm our preliminary results with in vivo dosimetry in non-pregnant breast cancer patients receiving electron beam intraoperative radiotherapy (ELIOT) and to report on the first treatment in a pregnant woman. Patients and Methods: Following our previous experience, 5 non-pregnant patients receiving ELIOT to the tumor bed after breast-conserving surgery (BCS) were studied with thermoluminescent dosimeters positioned in the subdiaphragmatic region, within the uterus, and in the ovarian region...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456470/is-mastectomy-oncologically-safer-than-breast-conserving-treatment-in-early-breast-cancer
#7
REVIEW
Fabian Riedel, André Hennigs, Sarah Hug, Benedikt Schaefgen, Christof Sohn, Florian Schuetz, Michael Golatta, Jörg Heil
Aim: To describe and discuss the evidence for oncological safety of different procedures in oncological breast surgery, i.e. breast-conserving treatment versus mastectomy. Methods: Literature review and discussion. Results: Oncological safety in breast cancer surgery has many dimensions. Breast-conserving treatment has been established as the standard surgical procedure for primary breast cancer and fits to the preferences of most breast cancer patients concerning oncological safety and aesthetic outcome...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456469/prophylactic-surgery-for-whom-when-and-how
#8
REVIEW
Christine Mau, Michael Untch
Risk-reducing surgery has proved to be a reasonable procedure in healthy women with a definitely elevated risk of developing cancer. Here we consider the elevated risk of breast and ovarian cancer. There is a clear indication for such surgery in healthy women with a pathogenic BRCA1/2 mutation. For these patients, a risk-reducing bilateral mastectomy leads to a verifiable reduction in mortality from breast cancer, particularly for young patients. In most cases, surgery is combined with breast reconstruction...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456468/psychosocial-aspects-of-immediate-versus-delayed-breast-reconstruction
#9
REVIEW
Anne-Sophie Heimes, Kathrin Stewen, Annette Hasenburg
Background: Only little is known about the psychosocial aspects of breast cancer patients after mastectomy with immediate versus delayed breast reconstruction. Methods: We systematically screened PubMed using the following key words: mastectomy, immediate vs. delayed reconstruction, psychosocial aspects and quality of life. To highlight different psychological outcomes, studies were categorized into those describing: anxiety, depression, body image and satisfaction with the surgical outcome...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456467/clinical-approaches-to-breast-reconstruction-what-is-the-appropriate-reconstructive-procedure-for-my-patient
#10
REVIEW
Max Dieterich, Adrian Dragu, Angrit Stachs, Johannes Stubert
Breast reconstruction after breast cancer is an emotional subject for women. Consequently, the correct timing and surgical procedure for each individual woman are important. In general, heterologous or autologous reconstructive procedures are available, both having advantages and disadvantages. Breast size, patient habitus, and previous surgeries or radiation therapy need to be considered, independent of the chosen procedure. New surgical techniques, refinement of surgical procedures, and the development of supportive materials have increased the general patient collective eligible for breast reconstruction...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456045/hepatectomy-for-octogenarians-with-colorectal-liver-metastasis-in-the-era-of-enhanced-recovery
#11
Andrea Tufo, Declan F J Dunne, Nichola Manu, Heman Joshi, Carmen Lacasia, Louise Jones, Hassan Z Malik, Graeme J Poston, Stephen W Fenwick
BACKGROUND: Concern exists regarding the use of hepatectomy to treat colorectal liver metastasis (CRLM) in octogenarians due to prior studies suggesting elevated morbidity and mortality. Cardiopulmonary exercise testing (CPET) within pre-operative assessment and enhanced recovery after surgery (ERAS) have both been shown to be associated with low morbidity and mortality in patients undergoing hepatectomy. This study sought to compare the outcomes of octogenarians with patients aged 70-79 undergoing hepatectomy for CRLM, within a center utilizing both CPET and ERAS...
February 6, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29455839/effects-of-radiation-and-surgery-on-function-and-quality-of-life-in-rectal-cancer-patients
#12
Amir Bastawrous
No abstract text is available yet for this article.
February 1, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29455653/novel-targeted-therapies-and-immunotherapy-for-advanced-thyroid-cancers
#13
REVIEW
George E Naoum, Michael Morkos, Brian Kim, Waleed Arafat
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable prognosis of this disease, 15-20% of differentiated thyroid cancer (DTC) cases and most anaplastic types, remain resistant to standard treatment options, including radioactive iodine (RAI). In addition, around 30% of medullary thyroid cancer (MTC) cases show resistance after surgery. The evolving understanding of disease-specific molecular therapeutic targets has led to the approval of two targeted therapies (Sorafenib and Lenvatinib) for RAI refractory DTC and another two drugs (Vandetanib and Cabozantinib) for MTC...
February 19, 2018: Molecular Cancer
https://www.readbyqxmd.com/read/29455490/-clinical-application-of-anterior-thoracoscopically-assisted-surgery-with-posterior-one-stage-total-en-block-spondylectomy-for-thoracic-spinal-tumor
#14
Wen Xue, Xiao-Li Guan, Zeng-Ping Wang, Zhong-Yu Hao, Lin Liu, Yao-Wen Qian
OBJECTIVE: To investigate the clincial effects and feasibility of anterior thoracoscopically assisted surgery (TAS) with posterior one-stage total en block spondylectomy(TES) for thoracic spinal tumour. METHODS: From October 2014 to January 2016, 4 patients with thoracic spinal tumour were treated by anterior thoracoscopically assisted surgery with posterior one-stage total en block spondylectomy. There were 2 males and 2 females, aged 16, 35, 46, 60 years. Courses of disease were 1, 4, 6, 9 months...
September 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455302/patient-experiences-of-a-physiotherapy-led-multidisciplinary-rehabilitative-intervention-after-successful-treatment-for-oesophago-gastric-cancer
#15
A E Bennett, L O'Neill, D Connolly, E M Guinan, L Boland, S L Doyle, J O'Sullivan, J V Reynolds, J Hussey
PURPOSE: To qualitatively explore the perceived impact of a 12-week rehabilitative intervention for oesophago-gastric cancer survivors on their physical, mental and social wellbeing. METHODS: Of the 21 participants who completed the intervention, 19 took part in a semi-structured focus group interview. Four audio-taped focus groups were held, ranging in size from two to eight participants. Focus groups were transcribed and analysed using a descriptive qualitative approach...
February 18, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29455167/pulmonary-metastasis-in-rectal-cancer-a-retrospective-study-of-clinicopathological-characteristics-of-404-patients-in-chinese-cohort
#16
Hong-Da Pan, Gang Zhao, Qi An, Gang Xiao
OBJECTIVES: This study aim to investigate the incidence, timing and risk factors of metachronous pulmonary recurrence after curative resection in patients with rectal cancer. DESIGN: A retrospective cohort study. SETTING: This study was conducted at a tertiary referral cancer hospital. PARTICIPANTS: A total of 404 patients with rectal cancer who underwent curative resection from 2007 to 2012 at Beijing Hospital were enrolled in this study...
February 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29455110/nipple-sparing-bilateral-prophylactic-mastectomy-and-immediate-reconstruction-with-tiloop-%C3%A2-bra-mesh-in-brca1-2-mutation-carriers-a-prospective-study-of-long-term-and-patient-reported-outcomes-using-the-breast-q
#17
D Casella, G Di Taranto, M Marcasciano, S Sordi, A Kothari, T Kovacs, F Lo Torto, E Cigna, D Ribuffo, C Calabrese
BACKGROUND: Although demand for prophylactic mastectomy is increasing over time among women at a high risk for breast cancer, there is a paucity of studies on long term patient-reported outcomes after this procedure. METHODS: Between January 2011 and January 2015, 46 patients documented BRCA1/2 mutation carriers, eligible for prophylactic nipple-sparing mastectomy (NSM) and immediate breast prosthetic reconstruction were registered at our institutions. Patients underwent NSM and subcutaneous reconstruction with implant covered by a titanium-coated polypropylene mesh (TiLoop® )...
February 15, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29455011/hybrid-retrograde-celiac-artery-stenting-for-acute-mesenteric-ischemia-after-gastric-surgery
#18
Duarte Rego, Paulo Almeida, Paulo Soares, Rui Almeida
INTRODUCTION: Celiac artery (CA) occlusions/stenosis are infrequently associated with liver ischemia due to its unique vascularization where portal vein provides about 75% of liver's perfusion. Collateral flow from gastroduodenal artery also provides, in most cases, enough blood supply to prevent ischemic hepatitis. In cases where these collateral pathways are compromised severe liver ischemia can occur. METHODS: We present a case of acute mesenteric ischemia following gastric surgery that was treated with a hybrid retrograde CA stenting...
February 15, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29454737/adjuvant-radiotherapy-for-positive-lymph-nodes-of-oesophageal-squamous-cell-carcinoma-can-it-earn-promising-benefits-at-long-term-follow-up
#19
Y Ren, J Ye, W Xiong, J Zuo, Y He, M Tan, Y Yuan
PURPOSE: The value of adjuvant radiotherapy for patients with positive lymph nodes after curative resection of oesophageal squamous cell carcinoma is controversial. This study aims to investigate its long-term benefits in a specific cohort. PATIENTS AND METHODS: The charts between 1990 and 2003 from patients with positive lymph nodes were retrospectively reviewed. Those subjects were divided into adjuvant radiotherapy and surgery alone groups, with two subgroups defined by radiation dose (cutoff value: 50Gy)...
February 14, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29454572/presence-of-colon-carcinoma-cells-at-the-resection-line-may-cause-recurrence-following-stapling-anastomosis
#20
Tzu-Chi Hsu, Ming-Jen Chen
BACKGROUND/OBJECTIVE: The presence of carcinoma cells in the suture line may result in local recurrence. The purpose of this study was to assess whether carcinoma cells were present along the resection line where the distal clamp was applied. METHODS: During surgery, the rectum was clamped at least 3 cm distal to the palpable margin of the tumor mass. The rectum was divided distal and proximal to the clamp. The tissue inside the clamp was rinsed with normal saline, and the irrigation solution was sent for cytologic examination...
February 14, 2018: Asian Journal of Surgery
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