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https://www.readbyqxmd.com/read/29143932/forecasting-carbon-dioxide-emissions-based-on-a-hybrid-of-mixed-data-sampling-regression-model-and-back-propagation-neural-network-in-the-usa
#1
Xin Zhao, Meng Han, Lili Ding, Adrian Cantemir Calin
The accurate forecast of carbon dioxide emissions is critical for policy makers to take proper measures to establish a low carbon society. This paper discusses a hybrid of the mixed data sampling (MIDAS) regression model and BP (back propagation) neural network (MIDAS-BP model) to forecast carbon dioxide emissions. Such analysis uses mixed frequency data to study the effects of quarterly economic growth on annual carbon dioxide emissions. The forecasting ability of MIDAS-BP is remarkably better than MIDAS, ordinary least square (OLS), polynomial distributed lags (PDL), autoregressive distributed lags (ADL), and auto-regressive moving average (ARMA) models...
November 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29134942/intramammary-infusion-of-a-live-culture-of-lactococcus-lactis-in-ewes-to-treat-staphylococcal-mastitis
#2
Sebastian Alessandro Mignacca, Simone Dore, Liliana Spuria, Pietro Zanghì, Benedetta Amato, Ilaria Duprè, Federica Armas, Elena Biasibetti, Cristina Camperio, Stefano A Lollai, Maria Teresa Capucchio, Eugenia Agnese Cannas, Vincenzo Di Marco Lo Presti, Cinzia Marianelli
PURPOSE: Alternatives to antibiotic therapy for mastitis in ruminants are needed. We present an evaluation, in two trials, of the efficacy of an intramammary infusion of a live culture of Lactococcus lactis for the treatment of subclinical and clinical mastitis in ewes. METHODOLOGY: In total, 67 animals were enrolled: 19 lactating ewes (study 1), including healthy (N=6) and coagulase-negative staphylococci (CNS)-infected ewes (N=13); and 48 lactating ewes (study 2) with either CNS mastitis (N=32), or Staphylococcus aureus mastitis (N=16), for a total of 123 mammary glands...
November 14, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29122341/effects-of-prescribed-fire-for-pasture-management-on-soil-organic-matter-and-biological-properties-a-1-year-study-case-in-the-central-pyrenees
#3
Antonio Girona-García, David Badía-Villas, Clara Martí-Dalmau, Oriol Ortiz-Perpiñá, Juan Luis Mora, Cecilia M Armas-Herrera
Prescribed burning has been readopted in the last decade in the Central Pyrenees to stop the regression of subalpine grasslands in favour of shrublands, dominated among others by Echinospartum horridum (Vahl) Rothm. Nevertheless, the effect of this practice on soil properties is uncertain. The aim of this work was to analyse the effects of these burnings on topsoil organic matter and biological properties. Soil sampling was carried out in an autumnal prescribed fire in Buisán (NE-Spain, November 2015). Topsoil was sampled at 0-1cm, 1-2cm and 2-3cm depth in triplicate just before (U), ~1h (B0), 6months (B6) and 12months (B12) after burning...
November 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29109730/t-follicular-helper-cells-and-b-cell-dysfunction-in-aging-and-hiv-1-infection
#4
REVIEW
Suresh Pallikkuth, Lesley de Armas, Stefano Rinaldi, Savita Pahwa
T follicular helper (Tfh) cells are a subset of CD4 T cells that provide critical signals to antigen-primed B cells in germinal centers to undergo proliferation, isotype switching, and somatic hypermutation to generate long-lived plasma cells and memory B cells during an immune response. The quantity and quality of Tfh cells therefore must be tightly controlled to prevent immune dysfunction in the form of autoimmunity and, on the other hand, immune deficiency. Both Tfh and B cell perturbations appear during HIV infection resulting in impaired antibody responses to vaccines such as seasonal trivalent influenza vaccine, also seen in biologic aging...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29109594/arma-cholesky-factor-models-for-the-covariance-matrix-of-linear-models
#5
Keunbaik Lee, Changryong Baek, Michael J Daniels
In longitudinal studies, serial dependence of repeated outcomes must be taken into account to make correct inferences on covariate effects. As such, care must be taken in modeling the covariance matrix. However, estimation of the covariance matrix is challenging because there are many parameters in the matrix and the estimated covariance matrix should be positive definite. To overcomes these limitations, two Cholesky decomposition approaches have been proposed: modified Cholesky decomposition for autoregressive (AR) structure and moving average Cholesky decomposition for moving average (MA) structure, respectively...
November 2017: Computational Statistics & Data Analysis
https://www.readbyqxmd.com/read/29104755/combined-approach-for-finding-susceptibility-genes-in-dish-chondrocalcinosis-families-whole-genome-wide-linkage-and-ibs-ibd-studies
#6
Ana Rita Couto, Bruna Parreira, Russell Thomson, Marta Soares, Deborah M Power, Jim Stankovich, Jácome Bruges Armas, Matthew A Brown
Twelve families with exuberant and early-onset calcium pyrophosphate dehydrate chondrocalcinosis (CC) and diffuse idiopathic skeletal hyperostosis (DISH), hereafter designated DISH/CC, were identified in Terceira Island, the Azores, Portugal. Ninety-two (92) individuals from these families were selected for whole-genome-wide linkage analysis. An identity-by-descent (IBD) analysis was performed in 10 individuals from 5 of the investigated pedigrees. The chromosome area with the maximal logarithm of the odds score (1...
2017: Human Genome Variation
https://www.readbyqxmd.com/read/29091224/in-vitro-activity-of-plazomicin-against-%C3%AE-lactamase-producing-carbapenem-resistant-enterobacteriaceae-cre
#7
Yunliang Zhang, Ankita Kashikar, Karen Bush
Background: Carbapenem-resistant Enterobacteriaceae (CRE) represent an urgent threat because few drugs are available to treat infections caused by these pathogens. Plazomicin is a novel aminoglycoside that recently completed a Phase 3 clinical trial for treatment of infections caused by CRE. Methods: A set of 110 characterized unique CRE patient isolates from central Indiana healthcare centres was tested by microbroth dilution for susceptibility to plazomicin, and to reference aminoglycosides and carbapenems...
October 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29066218/emergence-of-arma-a-16s-rrna-methylase-in-highly-aminoglycoside-resistant-clinical-isolates-of-klebsiella-pneumoniae-and-klebsiella-oxytoca-in-okinawa-japan
#8
Kohei Uechi, Tatsuya Tada, Kayo Shimada, Isamu Nakasone, Tetsu Sonozaki, Teruo Kirikae, Jiro Fujita
This study describes highly aminoglycoside-resistant Klebsiella pneumoniae and Klebsiella oxytoca clinical isolates obtained from an inpatient in Okinawa, Japan, with no known record of traveling overseas. The minimum inhibitory concentrations of amikacin and arbekacin against these strains were >1024 μg/ml. Whole-genome sequencing analysis revealed that these isolates harbored armA, which encodes a 16S rRNA methylase, ArmA, that confers pan-aminoglycoside resistance. This is the second report of K. pneumoniae harboring armA and the first report of K...
October 21, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29046481/reevaluation-of-immune-activation-in-the-era-of-cart-and-an-aging-hiv-infected-population
#9
Lesley R de Armas, Suresh Pallikkuth, Varghese George, Stefano Rinaldi, Rajendra Pahwa, Kristopher L Arheart, Savita Pahwa
Biological aging is associated with immune activation (IA) and declining immunity due to systemic inflammation. It is widely accepted that HIV infection causes persistent IA and premature immune senescence despite effective antiretroviral therapy and virologic suppression; however, the effects of combined HIV infection and aging are not well defined. Here, we assessed the relationship between markers of IA and inflammation during biological aging in HIV-infected and -uninfected populations. Antibody response to seasonal influenza vaccination was implemented as a measure of immune competence and relationships between IA, inflammation, and antibody responses were explored using statistical modeling appropriate for integrating high-dimensional data sets...
October 19, 2017: JCI Insight
https://www.readbyqxmd.com/read/29041175/initial-conditions-for-dissipative-solitons-in-a-strict-polarization-controlled-passively-mode-locked-er-fiber-laser
#10
H Santiago-Hernández, Y E Bracamontes-Rodríguez, G Beltrán-Pérez, I Armas-Rivera, L A Rodríguez-Morales, O Pottiez, B Ibarra-Escamilla, M Durán-Sánchez, M V Hernández-Arriaga, E A Kuzin
We report the dynamics of dissipative solitons in a ring cavity passively mode-locked fiber laser with a strict control of the polarization state. We study the relation between the polarization state of the pulses propagating in the cavity and the regimes of generation. We have found that at pulse ellipticities between 5° and 15°, the laser generates one bunch of pulses in the cavity, while at higher ellipticities the laser generates multiple bunches. At constant ellipticity we rotated the polarization azimuth and observed a regime transition from the generation of noise-like pulses (NLP) to that of soliton crystal...
October 16, 2017: Optics Express
https://www.readbyqxmd.com/read/29025429/updated-clinical-guidelines-experience-major-reporting-limitations
#11
Robin W M Vernooij, Laura Martínez García, Ivan Dario Florez, Laura Hildago Armas, Michiel H F Poorthuis, Melissa Brouwers, Pablo Alonso-Coello
BACKGROUND: The Checklist for the Reporting of Updated Guidelines (CheckUp) was recently developed. However, so far, no systematic assessment of the reporting of updated clinical guidelines (CGs) exists. We aimed to examine (1) the completeness of reporting the updating process in CGs and (2) the inter-observer reliability of CheckUp. METHODS: We conducted a systematic assessment of the reporting of the updating process in a sample of updated CGs using CheckUp. We performed a systematic search to identify updated CGs published in 2015, developed by a professional society, reporting a systematic review of the evidence, and containing at least one recommendation...
October 12, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29024237/sterol-content-in-the-artificial-diet-of-mythimna-separata-affects-the-metabolomics-of-arma-chinensis-fallou-as-determined-by-proton-nuclear-magnetic-resonance-spectroscopy
#12
Yi Guo, Chen-Xi Liu, Li-Sheng Zhang, Meng-Qing Wang, Hong-Yin Chen
Insects cannot synthesize sterols and must obtain them from plants. Therefore, reducing plant sterol content or changing sterol type might be an effective pest control strategy. However, the impacts of these changes on pests' natural predators remain unknown. Here, we fed artificial diets with reduced sterol content to Mythimna separata (Walker) (Lepidoptera: Noctuidae) and investigated the effects on its natural predator, Arma chinensis (Fallou) (Hemiptera: Pentatomidae). Reduced sterol content in M. separata (MS1, MS2, and MS5) was achieved by feeding them artificial diets prepared from a feed base subjected to one, two, or five cycles of sterol extractions, respectively...
October 11, 2017: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/29023396/diversity-and-antimicrobial-potential-of-predatory-bacteria-from-the-peruvian-coastline
#13
Luis Linares-Otoya, Virginia Linares-Otoya, Lizbeth Armas-Mantilla, Cyntia Blanco-Olano, Max Crüsemann, Mayar L Ganoza-Yupanqui, Julio Campos-Florian, Gabriele M König, Till F Schäberle
The microbiome of three different sites at the Peruvian Pacific coast was analyzed, revealing a lower bacterial biodiversity at Isla Foca than at Paracas and Manglares, with 89 bacterial genera identified, as compared to 195 and 173 genera, respectively. Only 47 of the bacterial genera identified were common to all three sites. In order to obtain promising strains for the putative production of novel antimicrobials, predatory bacteria were isolated from these sampling sites, using two different bait organisms...
October 12, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28993336/emergence-of-various-ndm-type-metallo-%C3%AE-lactamase-producing-escherichia-coli-clinical-isolates-in-nepal
#14
Basudha Shrestha, Tatsuya Tada, Kayo Shimada, Shovita Shrestha, Hiroshi Ohara, Bharat Mani Pokhrel, Jeevan Bdr Sherchand, Teruo Kirikae
Of 250 clinical isolates of Escherichia coli obtained in Nepal, 38 were carbapenem-resistant with MICs ≥4 μg/ml to imipenem or meropenem. All 38 isolates harbored blaNDMs: blaNDM-1, blaNDM-3, blaNDM-4, blaNDM-5, blaNDM-7, blaNDM-12 and blaNDM-13 Most of these isolates also harbored the 16S rRNA methylase gene(s) armA, rmtB and/or rmtC.
October 9, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28978128/psy153-mdr-a-p12969-dim-related-mega-plasmid-carrying-blaimp-45-and-arma-from-clinical-pseudomonas-putida
#15
Min Yuan, Hai Chen, Xiong Zhu, Jiao Feng, Zhe Zhan, Defu Zhang, Xia Chen, Xiaofei Zhao, Jinxing Lu, Jianguo Xu, Dongsheng Zhou, Juan Li
This work characterized mega plasmid pSY153-MDR, carrying blaIMP-45 and armA, from a multidrug-resistant (MDR) Pseudomonas putida isolate from the urine of a cerebral infarction patient in China. The backbone of pSY153-MDR was closely related to Pseudomonas plasmids p12969-DIM, pOZ176, pBM413, pTTS12, and pRBL16, and could not be assigned to any of the known incompatibility groups. The accessory modules of pSY153-MDR were composed of 10 individual insertion sequence elements and two different MDR regions, and differed dramatically from the above plasmids...
September 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28978016/epigenomic-study-identifies-a-novel-mesenchyme-homeobox2-gli1-transcription-axis-involved-in-cancer-drug-resistance-overall-survival-and-therapy-prognosis-in-lung-cancer-patients
#16
Leonel Armas-López, Patricia Piña-Sánchez, Oscar Arrieta, Enrique Guzman de Alba, Blanca Ortiz-Quintero, Patricio Santillán-Doherty, David C Christiani, Joaquín Zúñiga, Federico Ávila-Moreno
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be elucidated. Here, an epigenomic strategy was implemented to identify novel MEOX2 gene promoter transcription targets and propose a new molecular mechanism underlying lung cancer drug resistance and poor clinical prognosis...
September 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28957726/emergence-of-salmonella-enterica-serovar-indiana-and-california-isolates-with-concurrent-resistance-to-cefotaxime-amikacin-and-ciprofloxacin-from-chickens-in-china
#17
Yongxiang Wang, Anyun Zhang, Yongqiang Yang, Changwei Lei, Wei Jiang, Bihui Liu, Hongping Shi, Linghan Kong, Guangyang Cheng, Xiuzhong Zhang, Xin Yang, Hongning Wang
The aim of this study was to investigate the prevalence and characterization of Salmonella concerning the poultry industry in China. A total of 170 non-duplicate Salmonella isolates were recovered from the 1540 chicken samples. Among the Salmonella isolates from chickens, the predominant serovars were S. enterica serovar Enteritidis (S. Enteritidis) (49/170, 28.8%), S. enterica serovar Indiana (S. Indiana) (37/170, 21.8%) and S. enterica serovar California (S. California) (34/170, 20.0%). High antimicrobial resistance was observed for ciprofloxacin (68...
December 4, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28955488/diffuse-idiopathic-skeletal-hyperostosis-dish-where-we-are-now-and-where-to-go-next
#18
REVIEW
Reuven Mader, Jorrit-Jan Verlaan, Iris Eshed, Bruges-Armas Jacome, Piercarlo Sarzi Puttini, Fabiola Atzeni, Dan Buskila, Eyal Reinshtein, Irina Novofastovski, Abdallah Fawaz, de Vlam Kurt, Xenofon Baraliakos
Diffuse idiopathic skeletal hyperostosis (DISH) is a well-recognised entity characterised by calcifications and ossifications of the entheses affecting mainly the spine and peripheral sites. DISH is still insufficiently investigated and understood. The objective of this report is to highlight the present limitations of our understanding of the condition and suggest future research paths.
2017: RMD Open
https://www.readbyqxmd.com/read/28955330/perturbation-of-b-cell-gene-expression-persists-in-hiv-infected-children-despite-effective-antiretroviral-therapy-and-predicts-h1n1-response
#19
Nicola Cotugno, Lesley De Armas, Suresh Pallikkuth, Stefano Rinaldi, Biju Issac, Alberto Cagigi, Paolo Rossi, Paolo Palma, Savita Pahwa
Despite effective antiretroviral therapy (ART), HIV-infected individuals with apparently similar clinical and immunological characteristics can vary in responsiveness to vaccinations. However, molecular mechanisms responsible for such impairment, as well as biomarkers able to predict vaccine responsiveness in HIV-infected children, remain unknown. Following the hypothesis that a B cell qualitative impairment persists in HIV-infected children (HIV) despite effective ART and phenotypic B cell immune reconstitution, the aim of the current study was to investigate B cell gene expression of HIV compared to age-matched healthy controls (HCs) and to determine whether distinct gene expression patterns could predict the ability to respond to influenza vaccine...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28948003/the-hedgehog-gli-pathway-in-embryonic-development-and-cancer-implications-for-pulmonary-oncology-therapy
#20
REVIEW
Leonel Armas-López, Joaquín Zúñiga, Oscar Arrieta, Federico Ávila-Moreno
Transcriptional regulation and epigenetic mechanisms closely control gene expression through diverse physiological and pathophysiological processes. These include the development of germ layers and post-natal epithelial cell-tissue differentiation, as well as, involved with the induction, promotion and/or progression of human malignancies. Diverse studies have shed light on the molecular similarities and differences involved in the stages of embryological epithelial development and dedifferentiation processes in malignant tumors of epithelial origin, of which many focus on lung carcinomas...
September 1, 2017: Oncotarget
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