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https://www.readbyqxmd.com/read/28935349/spinal-ischemia-in-thoracic-aortic-procedures-impact-of-radiculomedullary-artery-distribution
#1
Fabian A Kari, Karin Wittmann, Sonja Krause, Babak Saravi, Luisa Puttfarcken, Katharina Förster, Bartosz Rylski, Sven Maier, Ulrich Göbel, Matthias Siepe, Martin Czerny, Friedhelm Beyersdorf
BACKGROUND: The aim of this study was to assess the influence of thoracic anterior radiculomedullary artery (tARMA) distribution on spinal cord perfusion in a thoracic aortic surgical model. METHODS: Twenty-six pigs (34 ± 3 kg; study group, n = 20; sham group, n = 6) underwent ligation of the left subclavian artery and thoracic segmental arteries. End points were spinal cord perfusion pressure (SCPP), regional spinal cord blood flow (SCBF), and neurologic outcome with an observation time of 3 hours...
September 18, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28934200/ten-simple-rules-for-successfully-completing-a-graduate-degree-in-latin-america
#2
EDITORIAL
Ernesto Ruelas Inzunza, Gabriela I Salazar-Rivera, Magdiel Láinez, María Guadalupe Ruiz-Gómez, Carlo A Domínguez-Eusebio, Griselda Cristóbal-Sánchez, Issaac A Teodosio Faustino, Edel Pérez-López, Meagan L Campbell, Marcus Vinicius Merfa, Ivonne Tatiana Latorre Beltrán, Fernanda Armas, Claudio Mota-Vargas
No abstract text is available yet for this article.
September 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28923459/complete-sequence-of-pbm413-a-novel-multi-drug-resistance-megaplasmid-carrying-qnrvc6-and-blaimp-45-from-pseudomonas-aeruginosa
#3
Junyan Liu, Ling Yang, Dingqiang Chen, Brian M Peters, Lin Li, Bing Li, Zhenbo Xu, Mark E Shirtliff
This study aimed to characterize a novel multi-drug-resistance megaplasmid carrying qnrVC6 and blaIMP-45 from Pseudomonas aeruginosa strain Guangzhou-Pae617 isolated from a hospital in Guangzhou, China in 2012. The plasmid pBM413 has a length of 423,017 bp and an average G+C content of 56.41%. A qnrVC6 gene flanked by two copies of ISCR1 elements, a multiresistance class 1 integron In786 containing aacA4→blaIMP-45→blaOXA-1→catB3 cassettes, an armA gene and an aphA7 gene flanked by two copies of IS26 elements were identified...
September 15, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28904641/histone-code-and-long-non-coding-rnas-lncrnas-aberrations-in-lung-cancer-implications-in-the-therapy-response
#4
REVIEW
Abril Marcela Herrera-Solorio, Leonel Armas-López, Oscar Arrieta, Joaquín Zúñiga, Patricia Piña-Sánchez, Federico Ávila-Moreno
Respiratory diseases hold several genome, epigenome, and transcriptional aberrations as a cause of the accumulated damage promoted by, among others, environmental risk factors. Such aberrations can also come about as an adaptive response when faced with therapeutic oncological drugs. In epigenetic terms, aberrations in DNA methylation patterns, histone code marks balance, and/or chromatin-remodeling complexes recruitment, among Polycomb Repressive Complex-2 (PRC2) versus Trithorax (TRX) Activator Complex, have been proposed to be affected by several previously characterized functional long non-coding RNAs (lncRNAs)...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28898956/long-short-term-memory-neural-network-for-air-pollutant-concentration-predictions-method-development-and-evaluation
#5
Xiang Li, Ling Peng, Xiaojing Yao, Shaolong Cui, Yuan Hu, Chengzeng You, Tianhe Chi
Air pollutant concentration forecasting is an effective method of protecting public health by providing an early warning against harmful air pollutants. However, existing methods of air pollutant concentration prediction fail to effectively model long-term dependencies, and most neglect spatial correlations. In this paper, a novel long short-term memory neural network extended (LSTME) model that inherently considers spatiotemporal correlations is proposed for air pollutant concentration prediction. Long short-term memory (LSTM) layers were used to automatically extract inherent useful features from historical air pollutant data, and auxiliary data, including meteorological data and time stamp data, were merged into the proposed model to enhance the performance...
September 8, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28893358/discrepant-susceptibility-to-gentamicin-despite-amikacin-resistance-in-klebsiella-pneumoniae-by-vitek-2-represents-false-susceptibility-associated-with-the-arma-16s-rrna-methylase-gene
#6
Jae-Hoon Ko, Jin Yang Baek, Kyong Ran Peck, Sun Young Cho, Young Eun Ha, So Hyun Kim, Hee Jae Huh, Nam Yong Lee, Cheol-In Kang, Doo Ryeon Chung, Jae-Hoon Song
Because we experienced gentamicin failure in Klebsiella pneumoniae bacteraemia that was susceptible to gentamicin despite amikacin resistance, as determined by VITEK 2, we evaluated the true susceptibility and mechanism of resistance. We screened 2818 K. pneumoniae isolates during a 1-year period at a university hospital and reviewed anti-microbial susceptibility reports using the VITEK 2 system. The minimum inhibitory concentration was substantiated by broth microdilution (BMD), and the presence of 16S rRNA methylase genes and aminoglycoside-modifying enzymes was also investigated...
September 12, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28891797/-overall-survival-and-renal-function-after-partial-and-radical-nephrectomy-in-malignant-localized-renal-tumors
#7
Paula León-Medina, Carolina Artiles-Ortega, José Vicente Armas-Molina, José Luis Artiles-Hernández
OBJECTIVE: To evaluate the overall survival rate and renal function in our series after radical nephrectomy (RN) and partial nephrectomy (PN) in renal tumors in an early stage. METHODS: We retrospectively reviewed the medical records of 229 patients who underwent RN or PN for renal cancer T1-T2N0M0 in our center between 1995 and 2015. We described demographic factors, first symptom, TNM, histology, post-surgery data, recurrence rate and renal function. We utilized Fisher test, Chi square test and T-Student and we considered statistical significance when p<0...
September 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28882733/-risk-of-fatal-non-fatal-events-in-patients-with-previous-coronary-heart-disease-acute-myocardial-infarction-and-treatment-with-non-steroidal-anti-inflammatory-drugs
#8
REVIEW
L Muñoz Olmo, J Juan Armas, J J Gomariz García
BACKGROUND: Primary Care is the fundamental axis of our health system and obliges us to be consistent with our prescriptions. The non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with increased cardiovascular risk and increased risk of all causes of death, as well as acute myocardial infarction (AMI) in patients with a previous myocardial infarction. Pain and cardiac patient management are 2 basic pillars in our daily activity, and we must know the limitations of NSAIDs in patients with established cardiovascular risk...
September 4, 2017: Semergen
https://www.readbyqxmd.com/read/28881399/heavy-atom-tunneling-calculations-in-thirteen-organic-reactions-tunneling-contributions-are-substantial-and-bell-s-formula-closely-approximates-multidimensional-tunneling-at-%C3%A2-250%C3%A2-k
#9
Charles Doubleday, Randy Armas, Dana Walker, Christopher V Cosgriff, Edyta M Greer
Multidimensional tunneling calculations are carried out for 13 reactions, to test the scope of heavy-atom tunneling in organic chemistry, and to check the accuracy of one-dimensional tunneling models. The reactions include pericyclic, cycloaromatization, radical cyclization and ring opening, and SN 2. When compared at the temperatures that give the same effective rate constant of 3×10(-5)  s(-1) , tunneling accounts for 25-95 % of the rate in 8 of the 13 reactions. Values of transmission coefficients predicted by Bell's formula, κBell  , agree well with multidimensional tunneling (canonical variational transition state theory with small curvature tunneling), κSCT ...
September 7, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28873396/a-mouse-mastitis-model-to-study-the-effects-of-the-intramammary-infusion-of-a-food-grade-lactococcus-lactis-strain
#10
Cristina Camperio, Federica Armas, Elena Biasibetti, Paolo Frassanito, Carlo Giovannelli, Liliana Spuria, Claudia D'Agostino, Sabrina Tait, Maria Teresa Capucchio, Cinzia Marianelli
Lactococcus lactis is one of the most important microorganisms in the dairy industry and has "generally recognized as safe" (GRAS) status. L. lactis belongs to the group of lactic acid bacteria (LAB) and is encountered in a wide range of environments. Recently, the use of the intramammary infusion of a live culture of LAB has been investigated as a new antibiotic alternative for treating mastitis in dairy ruminants. Controversial results are described in literature regarding its efficacy and safety. In this study we conducted in-depth investigation of the mammary gland immune response induced by intramammary inoculum of a live culture of L...
2017: PloS One
https://www.readbyqxmd.com/read/28870092/emergence-of-arma-and-rmtb-genes-among-vim-ndm-and-imp-metallo-%C3%AE-lactamase-producing-multidrug-resistant-gram-negative-pathogens
#11
Sangeetha Gopalakrishnan, Arunagiri Kamalanathan, Sivaranjani Rajan, Vijay Manohar Bhagat, M K Showkath Ali
In the recent years, it has been noted that microorganisms with acquired resistance to almost all available potent antibiotics are increasing worldwide. Hence, the use of antibiotics in every clinical setup has to be organized to avoid irrational use of antibiotics. This study was aimed to establish the pattern of antibiotic sensitivity and relevance of antimicrobial resistance in aerobic Gram-negative bacilli. A total of 103 aerobic Gram-negative bacteria namely Escherichia coli, Klebsiella pneumoniae, Enterobacter spp...
September 5, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28852405/predictive-determinants-of-scorpion-stings-in-a-tropical-zone-of-south-iran-use-of-mixed-seasonal-autoregressive-moving-average-model
#12
Vahid Ebrahimi, Esmael Hamdami, Mohammad Djaefar Moemenbellah-Fard, Shahrokh Ezzatzadegan Jahromi
BACKGROUND: More than 1.2 million scorpion stings occur annually worldwide, particularly in tropical regions. In the absence of proper medical care, mortality due to venomous scorpion stings is an important public health issue. The aim of the present study is to explore the temporal trend of scorpionism with time series models and determine the effective factors on this event using regression models. METHODS: A retrospective cross sectional study was conducted on 853 scorpion stung patients...
2017: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/28834219/human-leucocyte-antigens-class-ii-allele-and-haplotype-association-with-type-1-diabetes-in-madeira-island-portugal
#13
H Spínola, A Lemos, A R Couto, B Parreira, M Soares, I Dutra, J Bruges-Armas, A Brehm, S Abreu
This study confirms for Madeira Island (Portugal) population the Type 1 Diabetes (T1D) susceptible and protective Human leucocyte antigens (HLA) markers previously reported in other populations and adds some local specificities. Among the strongest T1D HLA associations, stands out, as susceptible, the alleles DRB1*04:05 (OR = 7.3), DQB1*03:02 (OR = 6.1) and DQA1*03:03 (OR = 4.5), as well as the haplotypes DRB1*04:05-DQA1*03:03-DQB1*03:02 (OR = 100.9) and DRB1*04:04-DQA1*03:01-DQB1*03:02 (OR = 22.1), and DQB1*06:02 (OR = 0...
August 20, 2017: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/28820112/prevalence-study-of-plasmid-mediated-ampc-%C3%AE-lactamases-in-enterobacteriaceae-lacking-inducible-ampc-from-saudi-hospitals
#14
Baha Abdalhamid, Samar Albunayan, Alaa Shaikh, Nasreldin Elhadi, Reem Aljindan
PURPOSE: Enterobacteriaceae encoding plasmid-mediated AmpC (pAmpC) β-lactamases confer resistance to the third generation cephalosporins. pAmpC association with extended spectrum β-lactamases (ESBLs), plasmid-mediated quinolone resistance (PMQR) and aminoglycoside modifying enzymes (AMEs) is well documented. There are limited data regarding the epidemiology and clinical significance of pAmpC in Saudi Arabia. This study aimed to determine the prevalence of pAmpC and its coexistence with ESBLs, PMQR and AMEs in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis isolates in Saudi hospitals from January to December 2015...
September 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28771142/comparison-of-semi-automated-commercial-rep-pcr-fingerprinting-spoligotyping-12-locus-miru-vntr-typing-and-single-nucleotide-polymorphism-analysis-of-the-embb-gene-as-molecular-typing-tools-for-mycobacterium-bovis
#15
Federica Armas, Cristina Camperio, Luana Coltella, Serena Selvaggini, Maria Beatrice Boniotti, Maria Lodovica Pacciarini, Vincenzo Di Marco Lo Presti, Cinzia Marianelli
PURPOSE: Highly discriminatory genotyping strategies are essential in molecular epidemiological studies of tuberculosis. In this study we evaluated, for the first time, the efficacy of the repetitive sequence-based PCR (rep-PCR) DiversiLab Mycobacterium typing kit over spoligotyping, 12-locus mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and embB single nucleotide polymorphism (SNP) analysis for Mycobacterium bovis typing. METHODOLOGY: A total of 49 M...
August 4, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28765517/the-hedgehog-gli-pathway-in-embryonic-development-and-cancer-implications-for-pulmonary-oncology-therapy
#16
REVIEW
Armas López Leonel, Zúñiga Joaquín, Arrieta Oscar, Ávila-Moreno Federico
Transcriptional regulation and epigenetic mechanisms closely control gene expression through diverse physiological and pathophysiological processes. These include the development of germ layers and post-natal epithelial cell-tissue differentiation, as well as, involved with the induction, promotion and/or progression of human malignancies.Diverse studies have shed light on the molecular similarities and differences involved in the stages of embryological epithelial development and dedifferentiation processes in malignant tumors of epithelial origin, of which many focus on lung carcinomas...
July 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28763663/prediction-of-fish-catch-in-the-danube-river-based-on-long-term-variability-in-environmental-parameters-and-catch-statistics
#17
Marija M Smederevac-Lalić, Aleksandar J Kalauzi, Slobodan B Regner, Mirjana B Lenhardt, Zorana Z Naunovic, Aleksandar E Hegediš
The effects of physical factors on fish catch in the Serbian part of the Danube River were studied for period of six decades. The data on total catch for the Danube River from river kilometre 845 to river kilometre 1433 were collected from Statistical Office of the Republic of Serbia, while water level and water temperature data were collected from 16 water gauge stations along the investigated part of the Danube River for the period 1948-2009. Cross-correlation functions have been used to analyse the functional connection between Danube water level, water temperature and fish catch while ARMA model which combines cyclic (deterministic) and random (stochastic) components of the analysed sequences was used for the forecasts...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28755740/vascular-damage-and-kidney-transplant-outcomes-an-unfriendly-and-harmful-link
#18
REVIEW
Domingo Hernández, Javier Triñanes, Ana María Armas, Pedro Ruiz-Esteban, Juana Alonso-Titos, Ana Duarte, Miguel González-Molina, Eulalia Palma, Eduardo Salido, Armando Torres
Kidney transplant (KT) is the treatment of choice for most patients with chronic kidney disease, but this has a high cardiovascular mortality due to traditional and nontraditional risk factors, including vascular calcification. Inflammation could precede the appearance of artery wall lesions, leading to arteriosclerosis and clinical and subclinical atherosclerosis in these patients. Additionally, mineral metabolism disorders and activation of the renin-angiotensin system could contribute to this vascular damage...
July 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28754338/unexpected-diagnosis-of-renal-cell-carcinoma-after-thyroid-nodule-study
#19
José Antonio Casimiro Pérez, Desiré Armas Ojeda, María Asunción Acosta Mérida, Carlos Fernández Quesada, Joaquín Marchena Gómez
No abstract text is available yet for this article.
July 25, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28736573/a-rapid-and-efficient-in-vitro-regeneration-system-for-lettuce-lactuca-sativa-l
#20
Isabel Armas, Natalia Pogrebnyak, Ilya Raskin
BACKGROUND: Successful biotechnological improvement of crop plants requires a reliable and efficient in vitro regeneration system. Lettuce (Lactuca sativa L.), one the most important vegetable crops worldwide, is strongly genotype-dependent in terms of regeneration capacity, limiting the potential for biotechnological improvement of cultivars which show recalcitrance under currently available protocols. The effect of different nutrient sources, plant hormone combinations and activated charcoal supplementation on shoot induction efficiency was evaluated on the cultivar 'RSL NFR', which had previously shown poor regeneration efficiency...
2017: Plant Methods
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