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https://www.readbyqxmd.com/read/29862892/sex-drugs-and-rhetoric-the-case-of-flibanserin-for-female-sexual-dysfunction
#1
Judy Z Segal
In August, 2015, the US Food and Drug Administration approved Addyi (flibanserin) for the treatment of Hypoactive Sexual Desire Disorder in premenopausal women. Ten months before that, the FDA had held a Patient-Focused Drug Development Public Meeting to address the 'unmet need' for a pharmaceutical to treat that condition. I attended that meeting as a rhetorical observer. This essay is an account of persuasive strategies used on, and then by, the FDA, as it considered approving a drug that was not convincingly either safe or effective...
June 1, 2018: Social Studies of Science
https://www.readbyqxmd.com/read/29781924/changes-in-psychiatric-and-medical-conditions-and-health-care-utilization-following-a-diagnosis-of-sexual-assault-a-retrospective-cohort-study
#2
Kelly C Young-Wolff, Varada Sarovar, Daniella Klebaner, Felicia Chi, Brigid McCaw
INTRODUCTION: Sexual assault (SA) is alarmingly common and is associated with higher prevalence of psychiatric and medical conditions. However, many prior studies are limited to cross-sectional designs. Health care systems with electronic health records provide unique longitudinal data to examine whether SA is associated with changes in health and health care utilization. METHODS: The sample included 1350 Kaiser Permanente Northern California adult female patients with a SA diagnosis from 2009 to 2015 and 4050 adult female patients without a SA diagnosis, matched on age, medical facility, and continuous enrollment during the study period...
May 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29719332/long-term-outcomes-of-sigmoid-vaginoplasty-in-patients-with-disorder-of-sexual-development-our-experience
#3
Ved Bhaskar, Rahul J Sinha, Seema Mehrotra, C N Mehrotra, Vishwajeet Singh
Introduction: To report our experience with sigmoid vaginoplasty in patients with different forms of disorder of sexual development and their long-term follow-up. Materials and Methods: This is a retrospective study of patients who underwent sigmoid vaginoplasty between July 2004 and June 2015 at our center. Follow-up included a physical examination to assess vaginal length and width, cosmetic appearance of the neovagina, and occurrence of any complications. Results: The current study included eight patients with mean age 19...
April 2018: Urology Annals
https://www.readbyqxmd.com/read/29710218/fertility-and-birth-outcomes-in-women-with-epilepsy-seeking-pregnancy
#4
Page B Pennell, Jacqueline A French, Cynthia L Harden, Anne Davis, Emilia Bagiella, Evie Andreopoulos, Connie Lau, Nichelle Llewellyn, Sarah Barnard, Stephanie Allien
Importance: Prior studies report lower birth rates for women with epilepsy (WWE) but have been unable to differentiate between biological and social contributions. To our knowledge, we do not have data to inform WWE seeking pregnancy if their likelihood of achieving pregnancy is biologically reduced compared with their peers. Objective: To determine if WWE without a prior diagnosis of infertility or related disorders are as likely to achieve pregnancy within 12 months as their peers without epilepsy...
April 30, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29706561/sexual-health-during-postgraduate-training-european-survey-across-medical-specialties
#5
Alexandra Kristufkova, Mariana Pinto Da Costa, Gesthimani Mintziori, Juan Luis Vásquez, Anna J M Aabakke, Mikkel Fode
BACKGROUND: Sexual health problems are common. Therefore, training in sexual health is relevant for the clinical practice of trainees and early-career specialists in several specialties who deal with patients with sexual health problems. However, little is known about how sexual health training is provided across countries and specialties. AIM: To assess (i) sexual health training during postgraduate training programs in psychiatry, obstetrics and gynecology, urology, and endocrinology across Europe; (ii) the confidence of trainees and early-career specialists in dealing with patients with sexual health problems; and (iii) their need for further training in sexual health during postgraduate training programs...
April 26, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29615937/reflecting-on-the-germanwings-disaster-a-systematic-review-of-depression-and-suicide-in-commercial-airline-pilots
#6
Terouz Pasha, Paul R A Stokes
Background: The 2015 Germanwings Flight 9525 disaster, in which 150 people were killed after the co-pilot may have intentionally crashed the plane in a suicide attempt, highlights the importance of better understanding the mental health of commercial airline pilots. However, there have been few systematic reviews investigating the topic of mental health in commercial aviation. This systematic review aims to identify the types and prevalence of mental health disorders that commercial airline pilots experience with a focus on mood disorders and suicide risk...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29609914/an-online-cross-sectional-comparison-of-women-with-symptoms-of-persistent-genital-arousal-painful-persistent-genital-arousal-and-chronic-vulvar-pain
#7
Robyn A Jackowich, Leah Pink, Allan Gordon, Évéline Poirier, Caroline F Pukall
BACKGROUND: Persistent genital arousal disorder (PGAD) is an understudied condition characterized by unwanted physiologic genital arousal in the absence of subjective sexual arousal. Markos and Dinsmore (Int J STD AIDS 2013;24:852-858) theorized that PGAD shares a number of similarities with vulvodynia (unexplained chronic vulvar pain [CVP]), including symptom characteristics and comorbidities. AIM: To compare medical histories, symptom characteristics, pain characteristics, and daily functioning among women with persistent genital pain (PGA) (n = 42), painful PGA (n = 37), and CVP (n = 42) symptoms...
April 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29608132/mental-health-and-substance-use-disorder-comorbidity-among-methamphetamine-using-men-who-have-sex-with-men
#8
Jesse B Fletcher, Dallas Swendeman, Cathy J Reback
Men who have sex with men (MSM) exhibit elevated rates of mental health and substance use disorder relative to their non-MSM male counterparts. Methamphetamine use in particular has been associated with both neuronal damage and mental health disorders among MSM, and this study reports on the prevalence and comorbidity of DSM-5 mental health and substance use disorders in a sample of methamphetamine-using MSM. From March 2014 through January 2015, 286 methamphetamine-using MSM enrolled in a study to reduce methamphetamine use and sexual risk behaviors...
April 2, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29607345/women-s-perceptions-and-feelings-about-loss-of-their-sexual-desire-a-qualitative-study-in-iran
#9
Pouran Akhavan Akbari, Giti Ozgoli, Masoumeh Simbar, Mohammad Ali Besharat
Background: Reduced sexual desire leaves serious impacts on women's life. The current study aims to investigate the perceptions and concerns of Iranian women of reproductive age with female sexual interest and arousal disorder (FSIAD). Methods: This qualitative research was conducted using content analysis approach. Data were collected through seventeen in-depth interviews from October 2015 to June 2016. Purposive sampling was carried out from among reproductive-aged women suffering from FSIAD who responded to female sexual function index (FSFI) with mean scores of ≤3...
April 2018: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/29565752/improving-body-image-and-sexual-health-behaviors-among-college-women
#10
Stephanie L Grossman, Bianca Campagna, Hadley Brochu, Meline Odermatt, Rachel A Annunziato
OBJECTIVE: To conduct a pilot test to determine if the Body Project, an eating disorder prevention program, was able to reduce risky sexual behaviors. PARTICIPANTS: Twenty college-age women ages 18-21 (in March, 2015) who endorsed both body image dissatisfaction and previous or current sexual activity. METHODS: Participants were randomized to the Body Project or psychoeducational control group, and completed baseline, post-test, and 6-month follow-up measures assessing body image concerns, eating behaviors, and sexual behaviors and attitudes...
March 22, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29560152/exploring-factors-behind-pregnant-women-s-quality-of-life-in-iran-a-qualitative-study
#11
Farideh Kazemi, Fatemeh Nahidi, Nourossadat Kariman
Background and objective: Pregnancy-related physiologic and psychosocial alterations can impact on the body and cause symptoms which may affect quality of life. Since qualitative studies can provide more in-depth understanding of quality of life and its determining factors, this study was conducted with the aim of exploring factors affecting pregnant women's quality of life. Methods: A qualitative descriptive study with conventional content analysis approach was made using the conventional content analysis approach on a purposeful sample of sixteen pregnant Iranian women in Hamadan, Iran from May 2015 to December 2015...
December 2017: Electronic Physician
https://www.readbyqxmd.com/read/29559206/retrospective-study-of-the-prevalence-and-risk-factors-of-clitoral-adhesions-women-s-health-providers-should-routinely-examine-the-glans-clitoris
#12
Leen Aerts, Rachel S Rubin, Michael Randazzo, Sue W Goldstein, Irwin Goldstein
INTRODUCTION: The glans clitoris is covered by a prepuce that normally moves over the glans surface and can be retracted beyond the corona. Clitoral adhesions, ranging from mild to severe, occur when preputial skin adheres to the glans. Physical examination consistent with clitoral adhesions is based on the inability to visualize the entire glans corona. In this closed compartment, the space underneath the adherent prepuce and clitoris can become irritated, erythematous, or infected and can result in sexual dysfunction...
June 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29464451/the-co-occurrence-of-asexuality-and-self-reported-post-traumatic-stress-disorder-diagnosis-and-sexual-trauma-within-the-past-12-months-among-u-s-college-students
#13
Mike C Parent, Kevin P Ferriter
An increasing number of individuals identify as asexual. It is important to understand the relationship between a diagnosis of post-traumatic stress disorder or a history of sexual trauma co-occurs with asexual identity. We aimed to assess whether identification as asexual was associated with greater likelihood for self-reported PTSD diagnosis and history of sexual trauma within the past 12 months. Secondary data analysis was undertaken of a cross-sectional survey of 33,385 U.S. college students (12,148 male, 21,237 female), including 228 self-identified asexual individuals (31 male, 197 female), who completed the 2015-2016 Healthy Minds Study...
May 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29422006/inhibition-of-neurogenesis-by-zika-virus-infection
#14
Fahim Ahmad, Amna Siddiqui, Mohammad A Kamal, Sayed S Sohrab
The association between Zika virus infection and neurological disorder has raised urgent global alarm. The ongoing epidemic has triggered quick responses in the scientific community. The first case of Zika virus was reported in 2015 from Brazil and now has spread over 30 countries. Nearly four hundred cases of travel-associated Zika virus infection have also been reported in the United States. Zika virus is primarily transmitted by mosquito belongs to the genus Aedes that are widely distributed throughout the world including the Southern United States...
February 1, 2018: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/29407562/sex-of-sexual-partners-and-disordered-weight-control-behaviors-in-a-nationally-representative-sample-of-south-korean-adolescents
#15
Kimberly Y Yu, Yongjoo Kim, Jerel P Calzo, Jordan A Levinson, S Bryn Austin
Eating disorders are a serious and life-threatening health issue associated with physical and mental health problems. Stigma associated with sexual orientation is thought to be one contributor to eating disorders symptoms in U.S. adolescents. Additional research on disordered weight control behaviors in diverse populations is needed to better understand their etiology. To examine the association of sex of sexual partners with disordered weight control behaviors among South Korean adolescents, we analyzed survey data from 67,266 adolescents, ages 12-18 years, from the 2015 Korea Youth Risk Behavior Web-based Survey...
April 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29396022/ignorance-is-not-bliss-if-we-don-t-understand-hypoactive-sexual-desire-disorder-how-can-flibanserin-treat-it-commentary
#16
REVIEW
Ryan Anderson, Claire E Moffatt
BACKGROUND: Female sexual dysfunction (FSD) affects as many as 1 in every 3 women, with a significant portion of these with hypoactive sexual desire disorder (HSDD). These figures alone present significant psychological and pharmacologic challenges. Partly in response to this situation, in 2015 the US Food and Drug Administration approved flibanserin for the treatment of HSDD. This approval has drawn criticism on the grounds of efficacy and necessity. AIM: To better inform potential consumers about FSD, flibanserin and other interventions for the treatment of HSDD, the importance of understanding the mechanism of FSD, and the efficacy of flibanserin and to review existing relevant knowledge...
March 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29371820/nationwide-survey-of-urological-specialists-regarding-male-infertility-results-from-a-2015-questionnaire-in-japan
#17
Yasushi Yumura, Akira Tsujimura, Takashi Imamoto, Yukihiro Umemoto, Hideyuki Kobayashi, Koji Shiraishi, Takeshi Shin, Hisanori Taniguchi, Koji Chiba, Yasushi Miyagawa, Teruaki Iwamoto
Purpose: To investigate the incidence, etiology, treatment indications, and outcomes regarding infertile male patients in Japan. Methods: Between April, 2014 and March, 2015, the authors contacted 47 clinical specialists in male infertility who had been certified by the Japan Society for Reproductive Medicine. The participating clinicians were sent a questionnaire regarding information on their infertile patients, according to etiology and the number and success rates of male infertility operations that had been performed in their practice...
January 2018: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29294706/factor-structure-and-reliability-of-the-posttraumatic-cognitions-inventory-in-korean-female-victims-of-sexual-violence
#18
Kyoung Min Shin, Young Ki Chung, Nam Hee Kim, Kyoung Ah Kim, Hyoung Yoon Chang
Trauma-related cognitions play an important role in formation and persistence of posttraumatic stress symptoms. This study investigated the psychometric properties of the Korean version of the Posttraumatic Cognitions Inventory (PTCI) in a sample of 227 females who had experienced sexual violence. Data were collected from victims who sought victim support services following sexual violence between 2011 and 2015. The Impact of Event Scale-Revised, Beck Depression Inventory, and Beck Anxiety Inventory were used to measure posttraumatic stress disorder severity, depression, and anxiety, respectively...
April 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29175690/human-trafficking-education-for-nurse-practitioners-integration-into-standard-curriculum
#19
Rebecca M Lutz
BACKGROUND: Human trafficking is a crime resulting in serious negative health outcomes for the victims. To provide optimal care, thus improving health outcomes, healthcare providers must be able to identify victims as they seek care for acute and chronic physical illness, communicable diseases, sexually transmitted infections, and mental health disorders (Lederer and Wetzel, 2014; Oram et al., 2012). Unfortunately, healthcare providers lack appropriate knowledge of clues that would lead to victim identification...
February 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29171862/deployment-related-military-sexual-trauma-predicts-heavy-drinking-and-alcohol-problems-among-male-reserve-and-national-guard-soldiers
#20
Jennifer Fillo, Sarah Cercone Heavey, D Lynn Homish, Gregory G Homish
BACKGROUND: Military sexual trauma (MST) is associated with a range of deleterious mental and physical health consequences; however, far less attention has been paid to the associations between MST and negative health behaviors, such as substance abuse. This study examined 2 focal research questions: (i) What is the prevalence of experiencing MST during deployment among male Reserve and National Guard soldiers? and (ii) to what extent is the degree of MST exposure during deployment associated with frequent heavy drinking and alcohol problems postdeployment? METHODS: Data from male soldiers who had been deployed (N = 248) were drawn from the baseline wave of Operation: SAFETY (Soldiers And Families Excelling Through the Years) an ongoing study examining health among U...
January 2018: Alcoholism, Clinical and Experimental Research
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