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https://www.readbyqxmd.com/read/28543433/mumps-outbreak-in-a-tribal-population-from-the-union-territory-of-dadra-and-nagar-haveli-india
#1
Siddharth M Tilavat, Sunil R Vaidya, Venkat S Hamde
A cluster of parotitis cases (n=13) were observed in a tribal population of Vansda village from the Union Territory of Dadra and Nagar Haveli, India between 20(th) and 22(nd) week of 2016. Primary information was received by the local Infectious Disease Surveillance Program team, and subsequently field investigations were carried out in the affected area. Active surveillance was conducted till twice the incubation period from onset of the last surveyed case. For the laboratory investigations, 19 serum samples were collected from 11-suspected cases and their close contacts (n=8)...
May 20, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28542125/notes-from-the-field-measles-outbreak-at-a-united-states-immigration-and-customs-enforcement-facility-arizona-may-june-2016
#2
Heather Venkat, Ahmed M Kassem, Chia-Ping Su, Clancey Hill, Evan Timme, Graham Briggs, Kenneth Komatsu, Susan Robinson, Rebecca Sunenshine, Manisha Patel, Diana Elson, Paul Gastañaduy, Shane Brady
HASH(0x496be20)
May 26, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28505632/missed-opportunities-for-measles-mumps-rubella-vaccination-among-departing-u-s-adult-travelers-receiving-pretravel-health-consultations
#3
Emily P Hyle, Sowmya R Rao, Emily S Jentes, Amy Parker Fiebelkorn, Stefan H F Hagmann, Allison Taylor Walker, Rochelle P Walensky, Edward T Ryan, Regina C LaRocque
Background: Measles outbreaks continue to occur in the United States and are mostly due to infections in returning travelers. Objective: To describe how providers assessed the measles immunity status of departing U.S. adult travelers seeking pretravel consultation and to assess reasons given for nonvaccination among those considered eligible to receive the measles, mumps, rubella (MMR) vaccine. Design: Observational study in U.S. pretravel clinics...
May 16, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28501474/a-case-of-mumps-related-acute-encephalopathy-with-biphasic-seizures-and-late-reduced-diffusion
#4
Kyoko Hazama, Takashi Shiihara, Hiroyuki Tsukagoshi, Shunji Hasegawa, Yuri Dowa, Mio Watanabe
BACKGROUND: Mumps is a common childhood viral disease characterized by fever and swelling of the parotid gland. The prognosis is generally good, although some complications, such as encephalitis (0.1%), exist. Acute encephalopathy with biphasic seizures and late reduced diffusion is the most common type of acute encephalopathy. However, this type of encephalopathy has not been reported in association with mumps infection. PATIENT: A previously healthy 3-year-old Japanese boy had a brief convulsion after fever for 3days, and then had conscious disturbance and parotitis...
May 10, 2017: Brain & Development
https://www.readbyqxmd.com/read/28500809/investigating-mumps-outbreak-in-odisha-india-an-opportunity-to-assess-the-health-system-by-utilizing-the-essential-public-health-services-framework
#5
Sourabh Paul, Preetam B Mahajan, Jyotiranjan Sahoo, Vikas Bhatia, Sonu H Subba
AbstractMumps, a highly contagious, viral disease continues to spread in India, despite the availability of an effective vaccine. On November 24, 2014, we came across a suspected case of mumps in a 6-year-old boy in a village of Bhusandapur sector in Odisha. We initiated an outbreak investigation using standard techniques outlined by the Centers for Disease Control and Prevention, Atlanta, GA. This uncovered a silent epidemic of 94 case patients (10% of the population) over a period of 16 weeks between August and December 2014, in a single village, which had gone completely unnoticed by the existing health-care system...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28490424/waning-immunity-and-microbial-vaccines-workshop-of-the-national-institute-of-allergy-and-infectious-diseases
#6
Xin-Xing Gu, Stanley A Plotkin, Kathryn M Edwards, Alessandro Sette, Kingston H G Mills, Ofer Levy, Andrea J Sant, Annie Mo, William Alexander, Kristina T Lu, Christopher E Taylor
Since the middle of the 20th century, vaccines have made a significant public health impact controlling infectious diseases globally. Although long-term protection has been achieved with some vaccines, immunity wanes over time with others, resulting in outbreaks or epidemics of infectious diseases. Long-term protection against infectious agents with complex life cycles and antigenic variation remains a key challenge. Novel strategies to characterize the short and long-term immune responses to vaccines, and to induce immune responses that mimic natural infection have recently emerged...
May 10, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28489000/suboptimal-mmr2-vaccine-coverage-in-six-counties-in-norway-detected-through-the-national-immunisation-registry-april-2014-to-april-2017
#7
Maria Hagerup-Jenssen, Sigrun Kongsrud, Øystein Rolandsen Riise
In 2014, Norway became aware of potential low vaccination coverage for the second dose of measles-mumps-rubella vaccine (MMR2) in six of 19 counties. This was detected by comparing the national coverage (NC) for 16-year-olds extracted from the national immunisation registry SYSVAK with the annual status update for elimination of measles and rubella (ASU) reported to the World Health Organization (WHO). The existing method for calculating NC in 2014 did not show MMR2 coverage. ASU reporting on MMR2 was significantly lower then the NC and below the WHO-recommended 95% coverage...
April 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28488995/written-reminders-increase-vaccine-coverage-in-danish-children-evaluation-of-a-nationwide-intervention-using-the-danish-vaccination-register-2014-to-2015
#8
Camilla Hiul Suppli, Mette Rasmussen, Palle Valentiner-Branth, Kåre Mølbak, Tyra Grove Krause
We evaluated a national intervention of sending written reminders to parents of children lacking childhood vaccinations, using the Danish Vaccination Register (DDV). The intervention cohort included the full birth cohort of 124,189 children born in Denmark who reached the age of 2 and 6.5 years from 15 May 2014 to 14 May 2015. The reference cohort comprised 124,427 children who reached the age of 2 and 6.5 years from 15 May 2013 to 14 May 2014. Vaccination coverage was higher in the intervention cohort at 2...
April 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28487657/waning-immunity-is-associated-with-periodic-large-outbreaks-of-mumps-a-mathematical-modeling-study-of-scottish-data
#9
Dalila Hamami, Ross Cameron, Kevin G Pollock, Carron Shankland
Vaccination programs for childhood diseases, such as measles, mumps and rubella have greatly contributed to decreasing the incidence and impact of those diseases. Nonetheless, despite long vaccination programmes across the world, mumps has not yet been eradicated in those countries: indeed, large outbreaks continue. For example, in Scotland large outbreaks occurred in 2004, 2005, and 2015, despite introducing the MMR (Measles-Mumps-Rubella) vaccine more than 20 years ago. There are indications that this vaccine-preventable disease is re-emerging in highly vaccinated populations...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28481690/two-year-antibody-persistence-in-children-vaccinated-at-12-15%C3%A2-months-with-a-measles-mumps-rubella-virus-vaccine-without-human-serum-albumin
#10
Andrea A Berry, Remon Abu-Elyazeed, Clemente Diaz-Perez, Maurice A Mufson, Christopher J Harrison, Michael Leonardi, Jerry D Twiggs, Christopher Peltier, Stanley Grogg, Antonio Carbayo, Steven Shapiro, Michael Povey, Carmen Baccarini, Bruce L Innis, Ouzama Henry
One combined measles-mumps-rubella (MMR) vaccine without Human Serum Albumin (HSA) is currently licensed in the USA (M-M-R II; Merck, USA) and another has been developed (Priorix™ [MMR-RIT, GSK, Belgium]). In this follow-up study, children from USA or Puerto Rico, who had received one dose of M-M-R II or MMR-RIT at 12-15 months of age in the primary study (NCT00861744), were followed-up for two years post-vaccination. Anti-measles and anti-rubella antibodies were measured using Enzyme-Linked Immunosorbent Assay (ELISA), and anti-mumps antibodies using ELISA and plaque reduction neutralization (PRN) assays...
May 8, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28481286/infectious-diseases-and-tropical-cyclones-in-southeast-china
#11
Jietao Zheng, Weixiao Han, Baofa Jiang, Wei Ma, Ying Zhang
Southeast China is frequently hit by tropical cyclones (TCs) with significant economic and health burdens each year. However, there is a lack of understanding of what infectious diseases could be affected by tropical cyclones. This study aimed to examine the impacts of tropical cyclones on notifiable infectious diseases in southeast China. Disease data between 2005 and 2011 from four coastal provinces in southeast China, including Guangdong, Hainan, Zhejiang, and Fujian province, were collected. Numbers of cases of 14 infectious diseases were compared between risk periods and reference periods for each tropical cyclone...
May 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28478789/spatial-distribution-of-mumps-in-south-korea-2001-2015-identifying-clusters-and-population-risk-factors
#12
Y-J Choe, K Min, S-I Cho
In South Korea, the resurgence of mumps was noted primarily among school-aged children and adolescents since 2000. We analyzed spatial patterns in mumps incidence to give an indication to the geographical risk. We used National Notifiable Disease Surveillance System data from 2001 to 2015, classifying into three periods according to the level of endemicity. A geographic-weighted regression analysis was performed to find demographic predictors of mumps incidence according to district level. We assessed the association between the total population size, population density, percentage of children (age 0-19 years), timely vaccination rate of measles-mumps-rubella vaccines and the higher incidence rate of mumps...
May 8, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28466381/tetherin-antagonism-by-v-proteins-is-a-common-trait-among-the-genus-rubulavirus
#13
Keisuke Ohta, Yusuke Matsumoto, Morihiro Ito, Machiko Nishio
Tetherin (BST-2/CD317/HM1.24) is an anti-viral factor that restricts the budding of several enveloped viruses. Most of these viruses have evolved to encode tetherin antagonists. Our previous study demonstrated that the growth of human parainfluenza virus type 2 (hPIV-2), a member of the genus Rubulavirus in the family Paramyxoviridae, was inhibited by tetherin, and its V protein decreases the amount of cell surface tetherin by the interaction. In the present study, we investigated whether tetherin inhibits the growth of other rubulaviruses including PIV-5, mumps virus (MuV), simian virus 41, and hPIV-4, and whether their V proteins act as tetherin antagonists...
May 2, 2017: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/28465097/challenges-in-conducting-post-authorisation-safety-studies-pass-a-vaccine-manufacturer-s-view
#14
Catherine Cohet, Dominique Rosillon, Corinne Willame, Francois Haguinet, Marie-Noëlle Marenne, Sandrine Fontaine, Hubert Buyse, Vincent Bauchau, Laurence Baril
Post-authorisation safety studies (PASS) of vaccines assess or quantify the risk of adverse events following immunisation that were not identified or could not be estimated pre-licensure. The aim of this perspective paper is to describe the authors' experience in the design and conduct of twelve PASS that contributed to the evaluation of the benefit-risk of vaccines in real-world settings. We describe challenges and learnings from selected PASS of rotavirus, malaria, influenza, human papillomavirus and measles-mumps-rubella-varicella vaccines that assessed or identified potential or theoretical risks, which may lead to changes to risk management plans and/or to label updates...
April 29, 2017: Vaccine
https://www.readbyqxmd.com/read/28461066/seroprevalence-of-rubella-antibodies-and-determinants-of-susceptibility-to-rubella-in-a-cohort-of-pregnant-women-in-canada-2008-2011
#15
Nicolas L Gilbert, Jenny Rotondo, Janna Shapiro, Lindsey Sherrard, William D Fraser, Brian J Ward
Long term control of rubella and congenital rubella syndrome relies on high population-level immunity against rubella, particularly among women of childbearing age. In Canada, all pregnant women should be screened so that susceptible new mothers can be offered vaccination for rubella before discharge. This study was undertaken to estimate rubella susceptibility in a cohort of pregnant women in Canada and to identify associated socio-economic and demographic factors. Biobanked plasma samples were obtained from the Maternal-Infant Research on Environmental Chemicals (MIREC) study, in which pregnant women were recruited between 2008 and 2011...
April 28, 2017: Vaccine
https://www.readbyqxmd.com/read/28457672/antibody-persistence-in-children-aged-6-7years-one-year-following-booster-immunization-with-two-mmr-vaccines-applied-by-aerosol-or-by-injection
#16
José Luis Díaz Ortega, Deyanira Castaneda, Doris Ma Arellano Quintanilla, David Martínez, Silas P Trumbo, Jorge Fernández de Castro
IMPORTANCE: In a previous study on booster vaccination, we reported that two aerosolized MMR vaccines were as safe and immunogenic as injectable vaccines containing the same antigens. We now present results of antibody persistence one year after immunization. OBJECTIVE: To assess the antibody persistence for measles, mumps, and rubella one year following booster immunization. METHODS: We performed clinical and serological follow-up of participants in a previous study of Mexican children aged 6-7years, in which participants were randomized to four groups receiving, by aerosolized or by injection, the MMR SII vaccine (Serum Institute of India), or the MMR II (Merck Sharp & Dhome)...
May 25, 2017: Vaccine
https://www.readbyqxmd.com/read/28453330/resurgence-of-measles-and-mumps-not-just-a-childhood-problem
#17
Pratheeshaa Nageswaran, Lucy Jenner, Siba Prosad Paul
No abstract text is available yet for this article.
April 27, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28432833/cellular-and-humoral-immunity-after-vaccination-or-natural-infection-of-mumps
#18
Kihei Terada, Kimiko Hagihara, Tomohiro Oishi, Ippei Miyata, Hiroto Akaike, Satoko Ogita, Naoki Ohno, Kazunobu Ouchi
OBJECTIVE: This study measured cell-mediated immunity (CMI) and serum antibody levels to clarify the basis of breakthrough after vaccination and reinfection after mumps. METHODS: From a pool of 54 college students, 17 seronegative subjects and 14 subjects with intermediate levels of antibodies against mumps were vaccinated with a monovalent mumps vaccine and CMI was assessed using an interferon-γ release assay. RESULTS: CMI positivity in subjects classified by pre-existing antibody levels, which gave groups with titers of <2...
April 22, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28431124/childhood-vaccinations-and-risk-of-acute-lymphoblastic-leukaemia-in-children
#19
Signe Holst Søegaard, Klaus Rostgaard, Kjeld Schmiegelow, Mads Kamper-Jørgensen, Marie Hargreave, Henrik Hjalgrim, Anders Hviid
Background: It has been proposed that childhood vaccinations protect against acute lymphoblastic leukaemia (ALL) in children by modulation of future responses to common infections in childhood. However, the available studies provide inconsistent findings, and population-based cohort studies with longitudinal information on vaccinations are lacking. Methods: In a register-based cohort of all children born in Denmark from 1 January 1990 to 31 December 2008, followed up until age 15 years or 31 December 2009 ( n  = 1 225 404), we evaluated exposure to childhood vaccination and risk of childhood ALL, including information on ALL subtypes...
April 19, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28421976/-measles-after-mmr-vaccination
#20
R van Grootveld, L M Klitsie, D C M van der Kaay, A C T M Vossen, A C Dijkmans
BACKGROUND: The Dutch national vaccination program provides vaccination for mumps, measles and rubella (MMR vaccine) for all children. After vaccination with live attenuated viruses, the virus replicates on a limited scale. Replication may lead to mild symptoms occurring 5-14 days after MMR-vaccination, including fever, conjunctivitis and rash. Symptoms are comparable to those of a wildtype measles infection. CASE DESCRIPTION: A 14-month-old boy was admitted to the hospital with an impressive rash 13 days after MMR-vaccination...
2017: Nederlands Tijdschrift Voor Geneeskunde
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