Etienne Gayat, Matthieu Resche-Rigon, Olivier Morel, Matthias Rossignol, Jean Mantz, Armelle Nicolas-Robin, Nathalie Nathan-Denizot, Jean-Yves Lefrant, Frédéric J Mercier, Emmanuel Samain, Yann Fargeaudou, Emmanuel Barranger, Marie-Josèphe Laisné, Pierre-Henri Bréchat, Dominique Luton, Ingrid Ouanounou, Patricia Appa Plaza, Claire Broche, Didier Payen, Alexandre Mebazaa
PURPOSE: Severe postpartum haemorrhage (SPPH) is the leading cause of peripartum hysterectomy and maternal death. There are no easily measurable parameters that indicate the failure of medical therapy and the need for an advanced interventional procedure (AIP) to stop genital tract bleeding. The aim of the study was to define factors predictive of the need for an AIP in the management of emergent PPH. METHODS: The study included two phases: (1) an initial retrospective study of 257 consecutive patients with SPPH, allowing the determination of independent predictors of AIP, which were subsequently grouped in a predictive score, followed by (2) a multicentre study of 239 patients admitted during 2007, designed to validate the score...
November 2011: Intensive Care Medicine