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https://www.readbyqxmd.com/read/29346585/maternal-vaccination-with-a-mono-component-pertussis-toxoid-vaccine-is-sufficient-to-protect-infants-in-a-baboon-model-of-whooping-cough
#1
Parul Kapil, James F Papin, Roman F Wolf, Lindsey I Zimmerman, Leslie D Wagner, Tod J Merkel
Background: Bordetella pertussis is a human pathogen responsible for serious respiratory illness. The disease is most severe in infants too young to be vaccinated with most hospitalizations and deaths occurring within this age group. The Advisory Committee on Immunization Practices recommended immunization of pregnant women to protect infants from birth until their first vaccination at six to eight weeks of age. We previously demonstrated that maternal vaccination with licensed acellular pertussis vaccines protected newborn baboons from disease...
January 15, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29341984/effect-of-age-at-vaccination-on-rotavirus-vaccine-effectiveness-in-bolivian-infants
#2
Rachel M Burke, Jacqueline E Tate, Kimberly D Pringle, Manish Patel, Lucia H De Oliveira, Umesh D Parashar
BACKGROUND: Rotavirus vaccines are less effective in developing countries versus developed countries. One hypothesis for this difference in performance is that higher levels of maternal antibodies in developing countries may interfere with vaccine response, suggesting that delayed dosing could be beneficial. The present analysis aims to assess whether rotavirus vaccine effectiveness (VE) varies by age at vaccination during routine use in Bolivia. METHODS: Data were merged from two post-licensure evaluations of monovalent rotavirus vaccine (RV1) in Bolivia, where two doses of RV1 are recommended at two and four months of age...
January 16, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29337615/efficacy-of-massachusetts-and-793b-vaccines-against-infectious-bronchitis-moroccan-italy-02-virus-in-specific-pathogen-free-chickens-and-commercial-broilers
#3
Sakhia F Z Belkasmi, Siham Fellahi, Sajid Umar, Mattias Delpont, Maxence Delverdier, Marie-Noëlle Lucas, Céline Bleuart, Faouzi Kichou, Saâdia Nassik, Jean-Luc Guerin, Ouafaa Fassi Fihri, Mariette F Ducatez, Mohammed El Houadfi
The ability of commercial vaccines H120 and 4/91 to protect against Moroccan-Italy 02 infectious bronchitis virus (Mor-It02) was investigated in specific-pathogen-free (SPF) chickens and commercial broiler chickens. Commercial broiler chicks (Experiment 1) were vaccinated at the hatchery with H120 vaccine at Day 1, and challenged at Day 21 with 104 50% egg-infective dose (EID50) of Mor-It02. All chicks were observed daily for clinical signs attributable to Mor-It02 infection during the 10 days postchallenge (pc)...
December 2017: Avian Diseases
https://www.readbyqxmd.com/read/29335062/epidemiology-of-measles-cases-in-south-darfur-state-sudan-2011-2015
#4
Taha Hussein Musa, Rehab Ibrahim Kambo, Abdelkareem Abdallah Ahmed, Hassan Hussein Musa
Case-based surveillance measles data was defined according to World Health Organization (WHO) guidelines. A total of 511 measles cases were studied from 2011 to 2015 in Southern Darfur State, Sudan and 58.1% of cases were confirmed from Nyala city. About 43.4% of cases were males, 56.6% of cases were female, and 47.7% were children under five years old. Similarity, within February to June, the cases increased by 8.0% in children vaccinated through measles campaign, and 5.3% in children that used child vaccination card and 78...
December 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29334901/monitoring-vaccine-and-non-vaccine-hpv-type-prevalence-in-the-post-vaccination-era-in-women-living-in-the-basilicata-region-italy
#5
Francesca Carozzi, Donella Puliti, Cristina Ocello, Pasquale Silvio Anastasio, Espedito Antonio Moliterni, Emilia Perinetti, Laurence Serradell, Elena Burroni, Massimo Confortini, Paola Mantellini, Marco Zappa, Géraldine Dominiak-Felden
BACKGROUND: A large free-of-charge quadrivalent HPV (qHPV) vaccination program, covering four cohorts annually (women 11, 14, 17 and 24 years), has been implemented in Basilicata since 2007. This study evaluated vaccine and non-vaccine HPV prevalence 5-7 years post-vaccination program implementation in vaccinated and unvaccinated women. METHODS: This population-based, cross-sectional study was conducted in the public screening centers of the Local Health Unit in Matera between 2012 and 2014...
January 15, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29334373/prevention-of-tuberculosis-in-rhesus-macaques-by-a-cytomegalovirus-based-vaccine
#6
Scott G Hansen, Daniel E Zak, Guangwu Xu, Julia C Ford, Emily E Marshall, Daniel Malouli, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Emily Ainslie, Kurt T Randall, Andrea N Selseth, Parker Rundstrom, Lauren Herlache, Matthew S Lewis, Haesun Park, Shannon L Planer, John M Turner, Miranda Fischer, Christina Armstrong, Robert C Zweig, Joseph Valvo, Jackie M Braun, Smitha Shankar, Lenette Lu, Andrew W Sylwester, Alfred W Legasse, Martin Messerle, Michael A Jarvis, Lynn M Amon, Alan Aderem, Galit Alter, Dominick J Laddy, Michele Stone, Aurelio Bonavia, Thomas G Evans, Michael K Axthelm, Klaus Früh, Paul T Edlefsen, Louis J Picker
Despite widespread use of the bacille Calmette-Guérin (BCG) vaccine, tuberculosis (TB) remains a leading cause of global mortality from a single infectious agent (Mycobacterium tuberculosis or Mtb). Here, over two independent Mtb challenge studies, we demonstrate that subcutaneous vaccination of rhesus macaques (RMs) with rhesus cytomegalovirus vectors encoding Mtb antigen inserts (hereafter referred to as RhCMV/TB)-which elicit and maintain highly effector-differentiated, circulating and tissue-resident Mtb-specific CD4+ and CD8+ memory T cell responses-can reduce the overall (pulmonary and extrapulmonary) extent of Mtb infection and disease by 68%, as compared to that in unvaccinated controls, after intrabronchial challenge with the Erdman strain of Mtb at ∼1 year after the first vaccination...
January 15, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29328508/serologic-responses-and-effectiveness-of-hepatitis-a-vaccination-among-hiv-positive-individuals-during-the-outbreak-of-acute-hepatitis-a
#7
Kuan-Yin Lin, Szu-Min Hsieh, Hsin-Yun Sun, Yi-Chun Lo, Wang-Huei Sheng, Yu-Chung Chuang, Aristine Cheng, Sung-Ching Pan, Guan-Jhou Chen, Chien-Ching Hung, Shan-Chwen Chang
Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who have sex with men (MSM) in Asia-Pacific region, the United States, and several European countries since June 2015, and recently among persons who are homeless and use illicit drugs in the US. We evaluated the serologic responses and effectiveness of HAV vaccination in HIV-positive individuals during the outbreak in Taiwan. From June 1, 2015 to September 30, 2016, anti-HAV IgG was prospectively determined among all HIV-positive individuals...
January 12, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29324680/phylogenetic-analysis-and-characterization-of-a-sporadic-isolate-of-equine-influenza-a-h3n8-from-an-unvaccinated-horse-in-2015
#8
Chithra C Sreenivasan, Sunayana S Jandhyala, Sisi Luo, Ben M Hause, Milton Thomas, David E B Knudsen, Pamela Leslie-Steen, Travis Clement, Stephanie E Reedy, Thomas M Chambers, Jane Christopher-Hennings, Eric Nelson, Dan Wang, Radhey S Kaushik, Feng Li
Equine influenza, caused by the H3N8 subtype, is a highly contagious respiratory disease affecting equid populations worldwide and has led to serious epidemics and transboundary pandemics. This study describes the phylogenetic characterization and replication kinetics of recently-isolated H3N8 virus from a nasal swab obtained from a sporadic case of natural infection in an unvaccinated horse from Montana, USA. The nasal swab tested positive for equine influenza by Real-Time Quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR)...
January 11, 2018: Viruses
https://www.readbyqxmd.com/read/29318526/evaluation-of-the-protection-provided-by-hepatitis-b-vaccination-in-india
#9
Jacob Puliyel, Pathik Naik, Ashish Puliyel, Kishore Agarwal, Vandana Lal, Nimmi Kansal, Devki Nandan, Vikas Tripathi, Prashant Tyagi, Saroj K Singh, Rajeev Srivastava, Utkarsh Sharma, V Sreenivas
OBJECTIVE: In India, Hepatitis B vaccination is recommended at 6 wk except for hospital-deliveries. The authors examined protection afforded by the birth dose. METHODS: A case-control study was done. HBsAg and HBcAb were tested in 2671 children, 1 to 5 y and HBsAb was evaluated in a subset of 1413 children. Vaccination history was recorded. Cases were HBsAg carriers. In another analysis, children who got infected (HBsAg and/or HBcAb positive) were considered as cases...
January 10, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29317900/knowledge-attitudes-and-practices-related-to-tetanus-toxoid-vaccination-in-women-of-childbearing-age-a-cross-sectional-study-in-peri-urban-settlements-of-karachi-pakistan
#10
Yasir Shafiq, Asif Raza Khowaja, Mohammad Tahir Yousafzai, Syed Asad Ali, Anita Zaidi, Ali Faisal Saleem
Backgound: A higher incidence of neonatal tetanus implies failure of the vaccination program in Pakistan. Objectives: The objective of this study was to assess knowledge, attitudes and practices related to tetanus toxoid (TT) vaccine in women of childbearing age. Methods: We performed a cross-sectional survey in peri-urban Karachi, Pakistan, among women of childbearing age, stratified into three mutually exclusive groups as: married pregnant; married non-pregnant; and unmarried...
September 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29317560/a-new-combined%C3%A2-vaccine%C3%A2-against-measles-mumps-rubella-and-varicella-in-india
#11
Nitin Shah, Raunak Parikh, Giacomo Casabona, Shafi Kolhapure
A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated with MMR+/-V. Two doses efficacy, against all varicella is 94.1% and effectiveness reaches 91%. The most frequent solicited local adverse event after MMRV vaccine is redness, and fever is the most common solicited general symptom...
December 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29311098/repeated-influenza-vaccination-for-preventing-severe-and-fatal-influenza-infection-in-older-adults-a-multicentre-case-control-study
#12
Itziar Casado, Ángela Domínguez, Diana Toledo, Judith Chamorro, Jenaro Astray, Mikel Egurrola, María Amelia Fernández-Sierra, Vicente Martín, María Morales-Suárez-Varela, Pere Godoy, Jesús Castilla
BACKGROUND: The effectiveness of repeated vaccination for influenza to prevent severe cases remains unclear. We evaluated the effectiveness of influenza vaccination on preventing admissions to hospital for influenza and reducing disease severity. METHODS: We conducted a case-control study in 20 hospitals in Spain during the 2013/14 and 2014/15 influenza seasons. Community-dwelling adults aged 65 years or older who were admitted to hospital for laboratory-confirmed influenza were matched with inpatient controls by sex, age, hospital and admission date...
January 8, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29310361/severe-pertussis-infection-a-clinicopathological-study
#13
Fernando Palvo, Alexandre Todorovic Fabro, Maria Célia Cervi, Davi Casale Aragon, Fernando Silva Ramalho, Ana Paula de Carvalho Panzeri Carlotti
We aimed to investigate the clinicopathological features of pertussis in children admitted to a tertiary-care university hospital in Brazil.This was a retrospective cohort study of all pediatric hospital admissions with pertussis from January 1, 2008 to December 31, 2014. We also reported the autopsy findings in children who died.Fifty-five patients admitted to the hospital over the study period had laboratorial confirmation of Bordetella pertussis infection, 17 (30.9%) needed pediatric intensive care unit (PICU) admission and 6 (10...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29302647/detection-of-canine-parvovirus-antigen-in-dogs-in-kumasi-ghana
#14
R D Folitse, D O Kodie, E Amemor, D Dei, W Tasiame, V Burimuah, B O Emikpe
Background: Canine Parvovirus (CPV) in dogs has been documented in many countries. However, evidence of the infection is scanty in Ghana. This study was conducted to detect canine parvovirus antigen in dogs presented with diarrhoea to the Government Veterinary Clinic in Kumasi, Ghana. Materials and Methods: Faecal samples from 72 dogs presented with diarrhoea were tested for the presence of canine parvovirus antigen using commercially available rapid test kit (BIT® Rapid Colour Canine Parvovirus Ag Test Kit, BIOINDIST Co...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29300683/innovations-in-adult-influenza-vaccination-in-china-2014-2015-leveraging-a-chronic-disease-management-system-in-a-community-based-intervention
#15
Bo Yi, Suizan Zhou, Ying Song, Enfu Chen, Xuyin Lao, Jian Cai, Carolyn M Greene, Luzhao Feng, Jiandong Zheng, Hongjie Yu, Hongjun Dong
OBJECTIVES: To evaluate a community-based intervention that leveraged the non-communicable disease management system to increase seasonal influenza vaccination coverage among older adults in Ningbo, China. METHODS: From October 2014 - March 2015, we piloted the following on one street in Ningbo, China: educating community healthcare workers (C-HCWs) about influenza and vaccination; requiring C-HCWs to recommend influenza vaccination to older adults during routine chronic disease follow-up; and opening 14 additional temporary vaccination clinics...
January 4, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29299894/human-immunodeficiency-virus-hiv-and-hepatitis-virus-coinfection-among-hiv-infected-korean-patients-the-korea-hiv-aids-cohort-study
#16
Yong Chan Kim, Jin Young Ahn, June Myung Kim, Youn Jeong Kim, Dae Won Park, Young Kyung Yoon, Joon Young Song, Shin Woo Kim, Jin Soo Lee, Bo Youl Choi, Yun Su Choi, Ju Yeon Choi, Myung Guk Han, Chun Kang, Jun Yong Choi
BACKGROUND: Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29290303/serological-evidence-for-eight-globally-important-poultry-viruses-in-trinidad-tobago
#17
Arianne Brown Jordan, Jamie Sookhoo, Lemar Blake, Paul Crooks, Zul Mohammed, Judy Molawatti-Bisnath, Christine V F Carrington, Christopher A L Oura
Viruses affecting poultry cause significant levels of disease leading to severe economic losses among poultry farmers worldwide. The Americas region continues to be vulnerable to the spread of poultry viruses across the continents and Caribbean island chains. In Trinidad and Tobago (T&T) there is limited information on the viruses circulating in poultry. Many flock are vulnerable to infection and there are occasional outbreaks of disease resulting in high levels of morbidity and mortality. This study aims to identify important viruses of poultry circulating in T&T through a broad-based surveillance approach...
January 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29290298/quantification-of-mycobacterium-bovis-transmission-in-a-badger-vaccine-field-trial
#18
I Aznar, K Frankena, S J More, J O'Keeffe, G McGrath, M C M de Jong
In the UK and Ireland, Bacille Calmette-Guérin (BCG) vaccination of badgers has been suggested as one of a number of strategies to control or even eradicate Mycobacterium bovis infection in badgers. In this manuscript, we present the results of a badger field trial conducted in Ireland and discuss how the novel trial design and analytical methods allowed the effects of vaccination on protection against infection and, more importantly, on transmission to be estimated. The trial area was divided into three zones North to South (A, B and C) where vaccination coverages of 0, 50 and 100%, respectively, were applied...
January 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29285631/factors-associated-with-vaccination-status-of-children-aged-12-48-months-in-india-2012-2013
#19
Luke M Shenton, Abram L Wagner, Deepti Bettampadi, Nina B Masters, Bradley F Carlson, Matthew L Boulton
Objectives India has more unvaccinated children than any other country despite provision of free vaccines through the government's Universal Immunization Program. In this study, we calculated the proportion of children aged 12-48 months who were fully vaccinated, under-vaccinated, or who had not received any vaccines. Childhood, household, and sociocultural factors associated with under-vaccination and non-vaccination were evaluated. Methods Using data from India's 4th District-level Health and Facility Survey, 2012-2013 (DLHS-4) and the 2012-2013 Annual Health Survey (AHS), we calculated the proportion of children who were non-vaccinated, under-vaccinated, or fully vaccinated with 1 dose of Bacillus Calmette-Guérin, 3 doses of oral polio vaccine, 3 doses of diphtheria-pertussis-tetanus, and 1 dose of measles-containing vaccine...
December 28, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29277414/primary-hpv-testing-u-s-women-s-awareness-and-acceptance-of-an-emerging-screening-modality
#20
Mona Saraiya, Albert Kwan, Crystale Purvis Cooper
BACKGROUND: Primary HPV testing (without the Pap test) has recently been recommended as a cervical cancer screening option in the United States. U.S. women's awareness and acceptance of primary HPV testing were evaluated. METHODS: Data from a 2015 web-based survey of U.S. adults was examined. Analyses were limited to women who were ≥18years old, had not undergone a hysterectomy, had not been diagnosed with cervical cancer, and would accept cervical cancer screening (N=1309)...
December 22, 2017: Preventive Medicine
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