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https://www.readbyqxmd.com/read/28335014/impact-of-high-intensity-polio-eradication-activities-on-children-s-routine-immunization-status-in-northern-india
#1
Marco J Haenssgen
The objective of this article is to analyse and quantify the side effects of the Polio Eradication Initiative on routine immunization performance in India. Past studies have faced methodological challenges in assessing these side effects. This article offers a methodological alternative for health policy analysts. The research uses secondary household survey data from the Indian District-Level Household and Facility Survey (DLHS), focusing on children aged 10-30 months in the Northern Indian states of Uttar Pradesh (n = 34 327) and Bihar (n = 20 525)...
March 16, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28333909/notes-from-the-field-obstetric-tetanus-in-an-unvaccinated-woman-after-a-home-birth-delivery-kentucky-2016
#2
Anna Q Yaffee, David L Day, Glenda Bastin, Mary Powell, Sandra Melendez, Nancy Allen, Julie Miracle, Margaret Jones, Robert Brawley
No abstract text is available yet for this article.
March 24, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28328984/using-simulation-to-aid-trial-design-ring-vaccination-trials
#3
Matt David Thomas Hitchings, Rebecca Freeman Grais, Marc Lipsitch
BACKGROUND: The 2014-6 West African Ebola epidemic highlights the need for rigorous, rapid clinical trial methods for vaccines. A challenge for trial design is making sample size calculations based on incidence within the trial, total vaccine effect, and intracluster correlation, when these parameters are uncertain in the presence of indirect effects of vaccination. METHODS AND FINDINGS: We present a stochastic, compartmental model for a ring vaccination trial. After identification of an index case, a ring of contacts is recruited and either vaccinated immediately or after 21 days...
March 22, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28321789/longitudinal-study-of-bovine-rotavirus-group-a-in-newborn-calves-from-vaccinated-and-unvaccinated-dairy-herds
#4
Thaís Gomes Rocha, Fernanda Dornelas Florentino Silva, Fábio Gregori, Amauri Alcindo Alfieri, Maria da Glória Buzinaro, José Jurandir Fagliari
Reports of rotavirus excretion in calves usually result from cross-sectional studies, and in face of the conflicting results regarding protection of calves born to vaccinated dams against diarrhea, the aim of the present study was to evaluate rotavirus excretion in dairy calves born to vaccinated or unvaccinated dams, to identify the genotypes of bovine rotavirus group A (RVA) strains isolated from these animals as well as to investigate characteristics of the disease in naturally occurring circumstances throughout the first month of life...
March 20, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28320411/human-rotavirus-strains-circulating-in-venezuela-after-vaccine-introduction-predominance-of-g2p-4-and-reemergence-of-g1p-8
#5
Esmeralda Vizzi, Oscar A Piñeros, M Daniela Oropeza, Laura Naranjo, José A Suárez, Rixio Fernández, José L Zambrano, Argelia Celis, Ferdinando Liprandi
BACKGROUND: Rotavirus (RV) is the most common cause of severe childhood diarrhea worldwide. Despite Venezuela was among the first developing countries to introduce RV vaccines into their national immunization schedules, RV is still contributing to the burden of diarrhea. Concerns exist about the selective pressure that RV vaccines could exert on the predominant types and/or emergence of new strains. RESULTS: To assess the impact of RV vaccines on the genotype distribution 1 year after the vaccination was implemented, a total of 912 fecal specimens, collected from children with acute gastroenteritis in Caracas from February 2007 to April 2008, were screened, of which 169 (18...
March 21, 2017: Virology Journal
https://www.readbyqxmd.com/read/28302934/hepatitis-b-vaccination-status-among-japanese-travelers
#6
Kenichiro Yaita, Koji Yahara, Yoshiro Sakai, Jun Iwahashi, Kenji Masunaga, Nobuyuki Hamada, Hiroshi Watanabe
This study clarified the characteristics of travelers who received hepatitis B vaccinations. Subjects were 233 Japanese travelers who visited our clinic prior to travel. We summarized the characteristics of the clients and performed two comparative studies: first, we compared a hepatitis B-vaccinated group with an unvaccinated group; second, we compared a group that had completed the hepatitis B vaccine series with a group that did not complete the series. The hepatitis B vaccine was administered to 152 clients...
March 15, 2017: Kurume Medical Journal
https://www.readbyqxmd.com/read/28299201/lyssaviruses-and-rabies-current-conundrums-concerns-contradictions-and-controversies
#7
REVIEW
Charles Rupprecht, Ivan Kuzmin, Francois Meslin
Lyssaviruses are bullet-shaped, single-stranded, negative-sense RNA viruses and the causative agents of the ancient zoonosis rabies. Africa is the likely home to the ancestors of taxa residing within the Genus Lyssavirus, Family Rhabdoviridae. Diverse lyssaviruses are envisioned as co-evolving with bats, as the ultimate reservoirs, over seemingly millions of years. In terms of relative distribution, overt abundance, and resulting progeny, rabies virus is the most successful lyssavirus species today, but for unknown reasons...
2017: F1000Research
https://www.readbyqxmd.com/read/28298565/longterm-effectiveness-of-herpes-zoster-vaccine-among-patients-with-autoimmune-and-inflammatory-diseases
#8
Huifeng Yun, Fenglong Xie, John W Baddley, Kevin Winthrop, Kenneth G Saag, Jeffrey R Curtis
OBJECTIVE: The protection duration of herpes zoster (HZ) vaccination is unclear among patients with autoimmune (AI) diseases. METHODS: Using 2006-2013 Medicare data, HZ vaccinated patients with AI were matched 1:2 to unvaccinated HZ. Incidence rates (IR) and adjusted risk ratios over time were calculated using Poisson regression. RESULTS: Of 59,627 vaccinated patients, crude IR increased from 0.75/100 person-years during the first year post-vaccination to 1...
March 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28293154/coverage-and-predictors-of-routine-immunization-among-12-23-months-old-children-in-disaster-affected-communities-in-pakistan
#9
Shafiq Ur Rehman, Amna Rehana Siddiqui, Jamil Ahmed, Zafar Fatmi, Sayed Masoom Shah, Aisha Rahman, Mohammad Tahir Yousafzai
OBJECTIVES: We aimed this study to determine the relationship of various factors related to poor immunization in children in an earthquake affected community. MATERIALS AND METHODS: We conducted this cross-sectional study during 2007-2008 in Muzaffarabad district of Pakistani side of Kashmir. We selected 43 villages as clusters and in the second, 860 children between 12 and 24 months were selected from households through systematic sampling. Mothers of the eligible children were interviewed with a questionnaire...
January 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28285327/biochemical-properties-and-vaccine-effect-of-recombinant-tpx-3-from-schistosoma-japonicum
#10
Yanhui Han, Bin Zhao, Min Zhang, Yang Hong, Hongxiao Han, Xiaodan Cao, Ke Lu, Jiaojiao Lin, Zhiqiang Fu
Thioredoxin peroxidases (TPxs) play an important role in maintaining redox homeostasis and in protecting organisms from the accumulation of toxic reactive oxygen species (ROS). In this study, we isolated the thioredoxin peroxidase-3 gene of Schistosoma japonicum, SjTPx-3. The open reading frame (ORF) of SjTPx-3 was 663 bp encoding 220 amino acids with a molecular weight of 24.99 kDa and an isoelectric point of 6.20. Quantitative real-time reverse transcription-polymerase chain reaction indicated that SjTPx-3 was expressed in all different stages of the parasites, with highest expression in 35-day-old worms...
March 11, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28284607/transmission-of-porcine-reproductive-and-respiratory-syndrome-virus-1-to-and-from-vaccinated-pigs-in-a-one-to-one-model
#11
E Pileri, E Gibert, G E Martín-Valls, M Nofrarias, S López-Soria, M Martín, I Díaz, L Darwich, E Mateu
The present study examined transmission by contact of Porcine reproductive and respiratory syndrome virus (PRRSV) 1 in a one-to-one model to vaccinated and unvaccinated pigs and from vaccinated infected pigs to other vaccinated pigs. The experiment started by randomly assigning weaned pigs to groups V (n=24) and U (n=26). V pigs were vaccinated with a commercial live attenuated PRRSV vaccine and the U animals were kept as unvaccinated controls. Twenty-eight days later, 6U pigs were separated and allocated in individual boxes...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28284277/potential-of-a-bpv1-l1-vlp-vaccine-to-prevent-bpv1-or-bpv2-induced-pseudo-sarcoid-formation-and-safety-and-immunogenicity-of-ecpv2-l1-vlps-in-horse
#12
Edmund K Hainisch, Hans Abel-Reichwald, Saeed Shafti-Keramat, Barbara Pratscher, Annunziata Corteggio, Giuseppe Borzacchiello, Maria Wetzig, Christoph Jindra, Alexander Tichy, Reinhard Kirnbauer, Sabine Brandt
We have previously shown that immunization of horses with bovine papillomavirus type 1 (BPV1) L1 virus-like particles (VLPs) is safe and highly immunogenic and that BPV1 and bovine papillomavirus type 2 (BPV2) are closely related serotypes. Here we evaluated the protective potential of a BPV1 L1 VLP vaccine against experimental BPV1 and BPV2 challenge and studied the safety and immunogenicity of a bivalent equine papillomavirus type 2 (EcPV2)/BPV1 L1 VLP vaccine. Fourteen healthy horses were immunized with BPV1 L1 VLPs (100 µg per injection) plus adjuvant on days 0 and 28, while seven remained unvaccinated...
February 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28283011/-investigation-of-seropositivity-of-bordetella-pertussis-in-adults-in-a-university-hospital
#13
Lütfiye Öksüz, Nezahat Gürler, Ali Ağaçfidan
Whooping cough is a vaccine-preventable infectious diseases caused by Bordetella pertussis/parapertussis. Despite of routine immunization programs in the world, pertussis still remains endemic. Recently unvaccinated or partially immunized infants have infected with this pathogen and also increase of incidence was observed in adolescents and adults. The source of pertussis in newborns are attributed to household, especially due to the family members. Theaim of this study was to determine B.pertussis IgG antibody positivity by ELISA method in adults...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28278407/influenza-vaccination-coverage-among-pregnant-indigenous-women-in-the-northern-territory-of-australia
#14
Sarah A Moberley, Jolie Lawrence, Vanessa Johnston, Ross M Andrews
Pregnant Aboriginal and Torres Strait Islander women are at particular risk of severe illness and high attack rates of influenza infection. In Australia, routine seasonal influenza vaccination is currently strongly recommended for all pregnant women and women planning pregnancy, and is provided free of charge for all pregnant women. We sought to determine vaccination coverage, describe the trends and characteristics associated with influenza vaccine uptake and determine the validity of self-reported influenza vaccination in a population of Indigenous pregnant women who were participants of a vaccine trial, prior to and during the 2009 H1N1 influenza pandemic...
September 30, 2016: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28277900/influence-of-maternal-vaccination-against-diphtheria-tetanus-and-pertussis-on-the-avidity-of-infant-antibody-responses-to-a-pertussis-containing-vaccine-in-belgium
#15
Raïssa Nadège Caboré, Kirsten Maertens, Alexandre Dobly, Elke Leuridan, Pierre Van Damme, Kris Huygen
Maternal antibodies induced by vaccination during pregnancy cross the placental barrier and can close the susceptibility gap to pertussis in young infants up to the start of primary immunization. As not only the quantity but also the quality of circulating antibodies is important for protection, we assessed whether maternal immunization affects the avidity of infant vaccine-induced IgG antibodies, in the frame of a prospective clinical trial on pregnancy vaccination in Belgium. Infants born from Tdap (Boostrix®) vaccinated (N = 55) and unvaccinated (N = 26) mothers were immunized with a hexavalent pertussis containing vaccine (Infanrix Hexa®) at 8, 12 and 16 weeks, followed by a fourth dose at 15 months of age...
February 22, 2017: Virulence
https://www.readbyqxmd.com/read/28277236/-we-ve-been-together-we-don-t-have-it-we-re-fine-how-relationship-status-impacts-human-papillomavirus-vaccine-behavior-among-young-adult-women
#16
Erika L Thompson, Cheryl A Vamos, Diane M Straub, William M Sappenfield, Ellen M Daley
BACKGROUND: Vaccination against the human papillomavirus (HPV) has the potential to significantly reduce morbidity and mortality associated with genital warts and HPV-related cancers. However, HPV vaccination rates continue to be suboptimal among the "catch-up" population of 18- to 26-year-old women. One consistent risk factor for nonvaccination is being in a relationship. This study aimed to understand how relationship status and vaccination status impact risk perceptions and perceived need for the HPV vaccine among young adult women...
October 27, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28249015/impact-of-ten-valent-pneumococcal-conjugate-vaccine-on-pneumonia-in-finnish-children-in-a-nation-wide-population-based-study
#17
Arto A Palmu, Hanna Rinta-Kokko, Hanna Nohynek, J Pekka Nuorti, Terhi M Kilpi, Jukka Jokinen
BACKGROUND: The ten-valent pneumococcal conjugate vaccine (PCV10) was introduced into the Finnish National Vaccination Program (NVP) in September 2010 using a 2+1 schedule (3, 5, 12 months). We estimated the direct and indirect effects of PCV10 on pneumonia among children to evaluate the public health impact of the vaccine. METHODS: We conducted a nation-wide population-based, observational study comparing rates of pneumonia in children before and after the NVP introduction...
2017: PloS One
https://www.readbyqxmd.com/read/28248852/serosurveillance-of-hepatitis-a-in-a-region-which-adopted-the-universal-mass-vaccination
#18
Maria Filomena Gallone, Francesco Desiante, Maria Serena Gallone, Giovanna Barbuti, Silvio Tafuri, Cinzia Germinario
Hepatitis A is a common infectious disease worldwide that was endemic in many regions of Southern Italy, such as Apulia region. After a large hepatitis A outbreak occurred between 1996 and 1997, in Apulia an active-free immunization program that was targeted to new-borns and adolescents was started. The aim of this study is to investigate the hepatitis A seroprevalence in the adult Apulian population 18 years after the immunization program introduction, in order to evaluate the risk of new epidemics onset.The study was carried out from May 2011 to June 2012 among blood donors from Department of Transfusion Medicine and Blood Bank of Policlinico General Hospital in Bari...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28248121/-unusual-histopathological-picture-of-acute-lung-injury-in-different-stages-of-resorption-with-predominance-of-organizing-pneumonia-in-a%C3%A2-young-man-with-influenza-a%C3%A2-h1n1
#19
Daniel Farkaš, Radoslav Matěj, Marián Ml Švajdler, Marcela Sluková, Jana Seligová, Lucia Fröhlichová, Silvia Farkašová Iannaccone, Vlasta Vyhnálková, Alžbeta Ginelliová
In this case report the authors describe histomorphological findings of acute lung injury with laboratory-confirmed influenza type A(H1N1) pneumonia leading to the death of a 30 year-old unvaccinated man after 27 days of hospitalisation. Histologically all three types of acute lung injuries were unusually present (diffuse alveolar damage, acute interstitial pneumonia, organizing pneumonia) in different phases of resorption and reparation with transition to extensive fibrosis.
2017: Ceskoslovenská Patologie
https://www.readbyqxmd.com/read/28245940/risk-stacking-of-pneumococcal-vaccination-indications-increases-mortality-in-unvaccinated-adults-with-streptococcus-pneumoniae-infections
#20
Jacob B Morton, Haley J Morrill, Kerry L LaPlante, Aisling R Caffrey
BACKGROUND: Several chronic disease states have been identified as pneumococcal vaccination indications due to their ability to increase pneumococcal disease development and subsequent mortality. However, the risk of mortality according to the number of these disease states present is unknown. We sought to determine the impact of concomitant, multiple risk factors (stacked risks) for pneumococcal disease on 30-day mortality in adults. METHODS: This was a national case-control study of unvaccinated older Veterans (≥50years of age) admitted to Veterans Affairs medical centers from 2002 to 2011 with serious pneumococcal infections (pneumonia, bacteremia, meningitis) based on positive S...
February 25, 2017: Vaccine
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