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https://www.readbyqxmd.com/read/29148564/differential-processing-in-modality-specific-mauthner-cell-dendrites
#1
V Medan, T Mäki-Marttunen, J Sztarker, T Preuss
Animals process multimodal information for adaptive behavioural decisions. In fish, evasion of a diving bird that breaks the water surface depends on integrating visual and auditory stimuli with very different characteristics. How do neurons process such differential sensory inputs at the dendritic level? For that we studied the Mauthner-cells (M-cells) in the goldfish startle circuit, which receive visual and auditory inputs via two separate dendrites, both accessible for in vivo recordings. We asked if electrophysiological membrane properties and dendrite morphology, studied in vivo, play a role in selective sensory processing in the M-cell...
November 17, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29146435/epidemiology-and-management-of-spinal-trauma-in-children-and-adolescents-under-18-years-old
#2
Asdrubal Falavigna, Orlando Righesso, Pedro Guarise da Silva, Felix Adolfo Sanchez Chavez, Ericson Sfreddo, Leandro Pelegrini de Almeida, Manuel Jose Valencia Carrasco, Andrei Fernandes Joaquim
STUDY DESIGN: Retrospective study. OBJECTIVE: Report the epidemiology, clinical aspects and management of spinal trauma in children and adolescents. METHODS: Multicenter study of 215 cases of spinal trauma in individuals younger than 18 years of age. All patients were submitted to preoperative and postoperative radiological and clinical evaluation. The fractures were classified according to the AOSpine fracture classification. Neurological evaluation was performed using the Frankel Scale at admission to hospital and at the last follow-up...
November 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29142117/long-necks-enhance-and-constrain-foraging-capacity-in-aquatic-vertebrates
#3
Rory P Wilson, Agustina Gómez-Laich, Juan-Emilio Sala, Giacomo Dell'Omo, Mark D Holton, Flavio Quintana
Highly specialized diving birds display substantial dichotomy in neck length with, for example, cormorants and anhingas having extreme necks, while penguins and auks have minimized necks. We attached acceleration loggers to Imperial cormorants Phalacrocorax atriceps and Magellanic penguins Spheniscus magellanicus, both foraging in waters over the Patagonian Shelf, to examine the difference in movement between their respective heads and bodies in an attempt to explain this dichotomy. The penguins had head and body attitudes and movements that broadly concurred throughout all phases of their dives...
November 29, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29140136/salt-glycerol-induced-hyperhydration-enhances-fluid-retention-more-than-salt-or-glycerol-induced-hyperhydration
#4
Eric D B Goulet, Adrien De La Flore, Félix A Savoie, Jonathan Gosselin
Hyperhydration has been demonstrated to improve work capacity and cardiovascular and thermoregulatory functions, enhance orthostatic tolerance, slow or neutralize bone demineralization and decrease post-dive bubble formation. Adding sodium or glycerol to a hyperhydration solution optimizes fluid retention. Sodium and glycerol produce their effect through different physiological mechanisms. If combined into a hyperhydration solution their impact on fluid retention could potentially be greater than their singular effect...
November 15, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29138511/intrinsic-and-extrinsic-factors-drive-ontogeny-of-early-life-at-sea-behaviour-in-a-marine-top-predator
#5
Matt I D Carter, Deborah J F Russell, Clare B Embling, Clint J Blight, David Thompson, Philip J Hosegood, Kimberley A Bennett
Young animals must learn to forage effectively to survive the transition from parental provisioning to independent feeding. Rapid development of successful foraging strategies is particularly important for capital breeders that do not receive parental guidance after weaning. The intrinsic and extrinsic drivers of variation in ontogeny of foraging are poorly understood for many species. Grey seals (Halichoerus grypus) are typical capital breeders; pups are abandoned on the natal site after a brief suckling phase, and must develop foraging skills without external input...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29137792/effects-of-radiator-shapes-on-the-bubble-diving-and-dispersion-of-ultrasonic-argon-process
#6
Xuan Liu, Jilai Xue, Qiang Zhao, Qichi Le, Zhiqiang Zhang
In this work, three ultrasonic radiators in different shapes have been designed in order to investigate the effects of radiator shapes on the argon bubble dispersion and diving as well as the degassing efficiency on magnesium melt. The radiator shape has a strong influence on the bubble diving and dispersion by ultrasound. A massive argon bubble slowly flows out from the radiator with the hemispherical cap, due to the covering hemispherical cap. Using a concave radiator can intensively crush the argon bubbles and drive them much deep into the water/melt, depending on the competition between the argon flow and opposite joint shear force from the concave surface...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29133857/pdgfr-modulated-mir-23b-cluster-and-mir-125a-5p-suppress-lung-tumorigenesis-by-targeting-multiple-components-of-kras-and-nf-kb-pathways
#7
Srivatsava Naidu, Lei Shi, Peter Magee, Justin D Middleton, Alessandro Laganá, Sudhakar Sahoo, Hui Sun Leong, Melanie Galvin, Kristopher Frese, Caroline Dive, Vincenza Guzzardo, Matteo Fassan, Michela Garofalo
In NSCLC alterations in PDGF receptors are markers of worst prognosis and efficient targeting of these receptors is yet to be achieved. In this study, we explored PDGFR-regulated microRNAs demonstrating that miR-23b cluster and miR-125a-5p are downregulated by increased expression of PDGFR-α or PDGFR-β in NSCLC cells. Mechanistically, the expression of these microRNAs is positively regulated by p53 and negatively modulated by NF-kB p65. Forced expression of miR-23b cluster or miR-125a-5p enhanced drug sensitivity and suppressed invasiveness of NSCLC cells by silencing several genes involved in oncogenic KRAS and NF-kB pathways, including SOS1, GRB2, IQGAP1, RALA, RAF-1, IKKβ, AKT2, ERK2 and KRAS itself...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29125799/body-growth-and-rapid-hematological-development-support-breath-hold-of-baby-belugas-delphinapterus-leucas-during-subice-transit
#8
Shawn R Noren, Caryn P Poll, Matthew S Edwards
Body size and oxygen stores in the blood and muscle set breath-hold limits in marine mammals, yet these characteristics are understudied in immature cetaceans. We examined body mass and hematology from birth through adulthood in beluga whales (Delphinapterus leucas). At birth, body mass was 8% and 6% of the maximum mass recorded for adult females and males, respectively. Body mass then increased rapidly, approaching an asymptote around 12 yr for females and 18 yr for males. Interestingly, red blood cell counts, hemoglobin content, and hematocrit levels decreased after birth; this neonatal anemia was reversed as levels increased after 2 mo postpartum...
January 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29123937/a-systematic-review-of-the-causes-and-management-of-ischaemic-stroke-caused-by-nontissue-emboli
#9
REVIEW
Ciaran Judge, Sarah Mello, David Bradley, Joseph Harbison
Introduction: The inadvertent or purposeful introduction of foreign bodies or substances can lead to cerebral infarction if they embolize to the brain. Individual reports of these events are uncommon but may increase with the increased occurrences of their risk factors, for example, intra-arterial procedures. Method: We searched EMBASE and MEDLINE for articles on embolic stroke of nontissue origin. 1889 articles were identified and screened and 216 articles were ultimately reviewed in full text and included in qualitative analysis...
2017: Stroke Research and Treatment
https://www.readbyqxmd.com/read/29122951/dive-heart-rate-in-harbour-porpoises-is-influenced-by-exercise-and-expectations
#10
Birgitte I McDonald, Mark Johnson, Peter T Madsen
The dive response, a decrease in heart rate (ƒH) and peripheral vasoconstriction, is the key mechanism allowing breath-hold divers to perform long duration dives. This pronounced cardiovascular response to diving has been investigated intensely in pinnipeds, but comparatively little is known for cetaceans, in particular in ecologically relevant settings. Here we studied the dive ƒH response in one the smallest cetaceans, the harbour porpoise (Phocoena phocoena). We used a novel multi-sensor data logger to record dive behaviour, ƒH, ventilations and feeding events in three trained porpoises, providing the first evaluation of cetacean ƒH regulation while performing a variety of natural behaviours, including prey capture...
November 9, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29118639/roa-rumsfeldi-a-new-butterflyfish-teleostei-chaetodontidae-from-mesophotic-coral-ecosystems-of-the-philippines
#11
Luiz A Rocha, Hudson T Pinheiro, Matt Wandell, Claudia R Rocha, Bart Shepherd
A new species of the butterflyfish genus Roa is herein described from the Verde Island Passage in the Philippines, West Pacific Ocean. Roa rumsfeldisp. n. was found on mesophotic coral ecosystems at Puerto Galera and Batangas, and sampled through technical mixed-gas rebreather diving at 100-130 m depth. This represents the fifth known species of Roa. The main differences between Roa rumsfeldisp. n. and its congeners are the lower number of pored scales in the lateral line, longer snout, longer caudal peduncle, shorter caudal fin, pelvic fin color (dark first spine vs...
2017: ZooKeys
https://www.readbyqxmd.com/read/29118600/a-revision-of-meladema-diving-beetles-coleoptera-dytiscidae-with-the-description-of-a-new-species-from-the-central-mediterranean-based-on-molecules-and-morphology
#12
David T Bilton, Ignacio Ribera
Meladema Laporte, 1835 are relatively large, stream-dwelling diving beetles, distributed widely in the Western Palaearctic, from the Atlantic Islands to Turkey, and from southern France and the Balkans to the central Sahara. In addition to the three previously recognised taxa (M. coriacea Laporte, 1835, M. imbricata (Wollaston, 1871) and M. lanio (Fabricius, 1775)) we describe a new, cryptic, species from the central Mediterranean area, which can be distinguished from M. coriacea on both DNA sequence data and morphology, and provide a key to known species of the genus...
2017: ZooKeys
https://www.readbyqxmd.com/read/29118373/establishing-zebrafish-as-a-model-to-study-the-anxiolytic-effects-of-scopolamine
#13
Trevor J Hamilton, Adam Morrill, Kayla Lucas, Joshua Gallup, Megan Harris, Meghan Healey, Taylor Pitman, Melike Schalomon, Shannon Digweed, Martin Tresguerres
Scopolamine (hyoscine) is a muscarinic acetylcholine receptor antagonist that has traditionally been used to treat motion sickness in humans. However, studies investigating depressed and bipolar populations have found that scopolamine is also effective at reducing depression and anxiety symptoms. The potential anxiety-reducing (anxiolytic) effects of scopolamine could have great clinical implications for humans; however, rats and mice administered scopolamine showed increased anxiety in standard behavioural tests...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117262/benthic-colonization-in-newly-ice-free-soft-bottom-areas-in-an-antarctic-fjord
#14
Cristian Lagger, Natalia Servetto, Luciana Torre, Ricardo Sahade
Extended glacier retreat is among the main consequences of the rapid warming of the West Antarctic Peninsula. Particularly, in the inner part of Potter Cove (South Shetland Islands, Antarctica) large areas are now exposed to open sea conditions owing to the retreat of Fourcade glacier. During the 2010 austral summer, underwater photographic surveys were undertaken by SCUBA diving up to 30 m in these new ice-free areas 80 m from the glacier front. Our main aim was to investigate colonization and early succession of the benthic assemblages on soft-bottom areas...
2017: PloS One
https://www.readbyqxmd.com/read/29116696/spinal-decompression-sickness-in-an-artisanal-diving-fisherman-in-yucat%C3%A3-n-mexico-a-case-report
#15
Daniel Popa, Walter Chin, Oswaldo Huchim-Lara, Ian Grover
Artisanal fishermen around the world employ scuba and surface-supplied diving for their livelihoods and often undergo provocative dive profiles due to economic pressures. Consequently, rates of decompression sickness (DCS) are much greater than in recreational scuba divers. Here we present the case of a surface-supplied diving fisherman from the Yucatán Peninsula of Mexico, who suffered a significant episode of spinal DCS and underwent hyperbaric oxygen therapy treatments, with a favorable outcome. Additionally, we review the proposed mechanisms underlying spinal DCS...
2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29116695/repetitive-freshwater-diving-risk-factors-and-prevalence-of-barotrauma
#16
Stefanie Jansen, Moritz Friedo Meyer, Manuela Boor, Ruth Volland, Eberhard Daniel Pracht, Heinz Dieter Klünter, Karl-Bernd Hüttenbrink, Dirk Beutner, Maria Grosheva
OBJECTIVE: The aim was to investigate the influence of repetitive scuba diving in fresh water on the middle ear mucosa. The prevalence of middle ear barotrauma (MEB) and risk factors for MEB were evaluated. STUDY DESIGN: Prospective cohort study, Level of evidence 1b. METHODS: During three days, 23 divers made 144 repetitive dives in a freshwater lake. Participants underwent otoscopic examinations and were questioned about ENT-related complaints in the morning before the first dive, in between the dives and after the last dive...
2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29116694/efficacy-of-the-u-s-navy-treatment-tables-in-treating-dcs-in-103-recreational-scuba-divers
#17
Walter Chin, Ellie Joo, Scott Ninokawa, Daniel A Popa, Derek B Covington
Despite the fact that current decompression schedules reduce the risk of decompression sickness (DCS), recreational scuba divers continue to experience DCS. Therapy outcomes in these divers are difficult to track. Our study aims to understand the efficacy of the United States Navy (USN) Treatment Tables (5, 6, 6A, 9) in providing symptomatic relief among recreational scuba divers. We conducted a single-center retrospective review of recreational divers treated from 2003 to 2013. A total of 187 divers were identified: 84 divers were excluded, and the charts of the remaining 103 divers were independently reviewed by three clinicians...
2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29113019/diving-into-research-a-practical-guide-for-emergency-medicine-trainees
#18
Louise Cullen, Nathan Brown
No abstract text is available yet for this article.
November 7, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29111929/autonomy-information-and-paternalism-in-clinical-communication
#19
Lisa Dive
No abstract text is available yet for this article.
November 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/29109900/preventable-diving-related-ocular-barotrauma-a-case-report
#20
Serkan Ergözen
The mystical beauty of the subaquatic world is undoubtedly attractive, and many techniques and forms of equipment have been developed in the last few decades to allow us to explore the underwater world. A swimmer or diver needs swimming goggles or a diving mask to have clear vision because of the refraction problem between the eye and the water interface. Although these items are effective for clear vision, they can result in "ocular or facial barotrauma of descent" during diving. It is possible to prevent these types of barotrauma with correct techniques and precautions, thus enabling the continuation of recreational diving without recurrence...
October 2017: Turkish Journal of Ophthalmology
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