Guillaume Bachelot, Ferdinand Dhombres, Nathalie Sermondade, Rahaf Haj Hamid, Isabelle Berthaut, Valentine Frydman, Marie Prades, Kamila Kolanska, Lise Selleret, Emmanuelle Mathieu-D'Argent, Diane Rivet-Danon, Rachel Levy, Antonin Lamazière, Charlotte Dupont
BACKGROUND: Testicular sperm extraction (TESE) is an essential therapeutic tool for the management of male infertility. However, it is an invasive procedure with a success rate up to 50%. To date, no model based on clinical and laboratory parameters is sufficiently powerful to accurately predict the success of sperm retrieval in TESE. OBJECTIVE: The aim of this study is to compare a wide range of predictive models under similar conditions for TESE outcomes in patients with nonobstructive azoospermia (NOA) to identify the correct mathematical approach to apply, most appropriate study size, and relevance of the input biomarkers...
June 21, 2023: Journal of Medical Internet Research