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JOURNAL ARTICLE
Chunfeng Li, Rui Wang, Shuai Zhang, Yuyuan Qin, Zhe Ying, Boyuan Wei, Zheng Dai, Fengyi Guo, Wei Chen, Rong Zhang, Baigeng Wang, Xuefeng Wang, Fengqi Song
Symmetry breaking in quantum materials is of great importance and can lead to non-reciprocal charge transport. Topological insulators provide a unique platform to study non-reciprocal charge transport due to their surface states, especially quantum Hall states under an external magnetic field. Here we report the observation of non-reciprocal charge transport mediated by quantum Hall states in devices composed of the intrinsic topological insulator Sn-Bi1.1 Sb0.9 Te2 S, which is attributed to asymmetric scattering between quantum Hall states and Dirac surface states...
April 19, 2024: Nature Materials
#22
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sakornsakolpat, Xingnan Li, Ruth Boxall, Nicola F Reeve, Ma'en Obeidat, Jing Hua Zhao, Matthias Wielscher, Stefan Weiss, Katherine A Kentistou, James P Cook, Benjamin B Sun, Jian Zhou, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E Harris, Jonathan Marten, Stefan Enroth, Shona M Kerr, Ida Surakka, Veronique Vitart, Terho Lehtimäki, Richard J Allen, Per S Bakke, Terri H Beaty, Eugene R Bleecker, Yohan Bossé, Corry-Anke Brandsma, Zhengming Chen, James D Crapo, John Danesh, Dawn L DeMeo, Frank Dudbridge, Ralf Ewert, Christian Gieger, Amund Gulsvik, Anna L Hansell, Ke Hao, Joshua D Hoffman, John E Hokanson, Georg Homuth, Peter K Joshi, Philippe Joubert, Claudia Langenberg, Xuan Li, Liming Li, Kuang Lin, Lars Lind, Nicholas Locantore, Jian'an Luan, Anubha Mahajan, Joseph C Maranville, Alison Murray, David C Nickle, Richard Packer, Margaret M Parker, Megan L Paynton, David J Porteous, Dmitry Prokopenko, Dandi Qiao, Rajesh Rawal, Heiko Runz, Ian Sayers, Don D Sin, Blair H Smith, María Soler Artigas, David Sparrow, Ruth Tal-Singer, Paul R H J Timmers, Maarten Van den Berge, John C Whittaker, Prescott G Woodruff, Laura M Yerges-Armstrong, Olga G Troyanskaya, Olli T Raitakari, Mika Kähönen, Ozren Polašek, Ulf Gyllensten, Igor Rudan, Ian J Deary, Nicole M Probst-Hensch, Holger Schulz, Alan L James, James F Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo-Riitta Jarvelin, Nick Wareham, Edwin K Silverman, Caroline Hayward, Andrew P Morris, Adam S Butterworth, Robert A Scott, Robin G Walters, Deborah A Meyers, Michael H Cho, David P Strachan, Ian P Hall, Martin D Tobin, Louise V Wain
No abstract text is available yet for this article.
April 19, 2024: Nature Genetics
#23
JOURNAL ARTICLE
Alicia M Hall, Noriko Kamei, Manlin Shao, Hyun-Seung Mun, Kevin Chen, Yuncai Chen, Tallie Z Baram
The mechanisms by which brain insults lead to subsequent epilepsy remain unclear. Insults including trauma, stroke, infections and long seizures (status epilepticus; SE) increase the nuclear expression and chromatin binding of the neuronal restrictive silencing factor / RE-1 silencing transcription factor (NRSF/REST). REST/NRSF orchestrates major disruption of the expression of key neuronal genes, including ion channels and neurotransmitter receptors, potentially contributing to epileptogenesis. Accordingly, transient interference with REST/NRSF chromatin binding after an epilepsy-provoking SE suppressed spontaneous seizures for the 12- day duration of a prior study...
April 19, 2024: ENeuro
#24
JOURNAL ARTICLE
E Bailey Terhune, Joseph Serino, Deborah J Hall, Denis Nam, Craig J Della Valle, Joshua J Jacobs, Robin Pourzal
BACKGROUND: Modular dual mobility (DM) bearings have a junction between a cobalt chrome alloy (CoCrMo) liner and titanium shell, and the risk of tribocorrosion at this interface remains a concern. The purpose of this study was to determine whether liner malseating and liner designs are associated with taper tribocorrosion. METHODS: We evaluated 28 retrieved modular DM implants with a mean in situ duration of 14.6 months (range, 1 to 83). There were two manufacturers included (12 and 16 liners, respectively)...
April 17, 2024: Journal of Arthroplasty
#25
JOURNAL ARTICLE
Xinyue Xu, Samuel J P Marlton, Kate L Flint, Rohan J Hudson, F Richard Keene, Christopher R Hall, Trevor A Smith
The metal-ligand charge transfer (3 MLCT) and phosphorescence-quenching metal-centered (3 MC) states of the helicate and mesocate diastereoisomers of a double-stranded dinuclear polypyridylruthenium(II) complex have been investigated using ultrafast transient absorption spectroscopy. At 294 K, transient signals of the helicate decayed significantly slower than those of the mesocate, whereas at 77 K, no clear contrast in kinetics was observed. Contributions to excited-state decay from high-lying 3 MLCT states were identified at both temperatures...
April 19, 2024: Journal of Physical Chemistry. A
#26
JOURNAL ARTICLE
Xiaoyu Liu, Yuchi He, Chong Wang, Xiao-Wei Zhang, Ting Cao, Di Xiao
A series of recent experimental works on twisted MoTe_{2} homobilayers have unveiled an abundance of exotic states in this system. Valley-polarized quantum anomalous Hall states have been identified at hole doping of ν=-1, and the fractional quantum anomalous Hall effect is observed at ν=-2/3 and ν=-3/5. In this Letter, we investigate the electronic properties of AA-stacked twisted bilayer MoTe_{2} at ν=-2 by k-space Hartree-Fock calculations. We identify a series of phases, among which a noteworthy phase is the antiferromagnetic Chern insulator, stabilized by an external electric field...
April 5, 2024: Physical Review Letters
#27
JOURNAL ARTICLE
G Tuvia, A Burshtein, I Silber, A Aharony, O Entin-Wohlman, M Goldstein, Y Dagan
Tunable spin-orbit interaction (SOI) is an important feature for future spin-based devices. In the presence of a magnetic field, SOI induces an asymmetry in the energy bands, which can produce nonlinear transport effects (V∼I^{2}). Here, we focus on such effects to study the role of SOI in the (111) LaTiO_{3}/SrTiO_{3} interface. This system is a convenient platform for understanding the role of SOI since it exhibits a single-band Hall response through the entire gate-voltage range studied. We report a pronounced rise in the nonlinear longitudinal resistance at a critical in-plane field H_{cr}...
April 5, 2024: Physical Review Letters
#28
JOURNAL ARTICLE
Mirza M Elahi, Hamed Vakili, Yihang Zeng, Cory R Dean, Avik W Ghosh
Transport measurement of electron optics in monolayer graphene p-n junction devices has been traditionally studied with negative refraction and chiral transmission experiments in Hall bar magnetic focusing setups. We show direct signatures of Klein (monolayer) and anti-Klein (bilayer) tunneling with a circular "edgeless" Corbino geometry made out of gated graphene p-n junctions. Noticeable in particular is the appearance of angular sweet spots (Brewster angles) in the magnetoconductance data of bilayer graphene, which minimizes head-on transmission, contrary to conventional Fresnel optics or monolayer graphene which show instead a sharpened collimation of transmission paths...
April 5, 2024: Physical Review Letters
#29
JOURNAL ARTICLE
Pietro Ameri, Valentina Mercurio, Piero Pollesello, Markus S Anker, Johannes Backs, Antoni Bayes-Genis, Barry A Borlaug, Daniel Burkhoff, Sergio Caravita, Stephen Y Chan, Frances de Man, George Giannakoulas, Aránzazu González, Marco Guazzi, Paul M Hassoun, Anna R Hemnes, Cristoph Maack, Brendan Madden, Vojtech Melenovsky, Oliver J Müller, Zoltan Papp, Soni Savai Pullamsetti, Peter P Rainer, Margaret M Redfield, Stuart Rich, Gabriele G Schiattarella, Hall Skaara, Kostantinos Stellos, Ryan J Tedford, Thomas Thum, Jean Luc Vachiery, Peter van der Meer, Sophie Van Linthout, Piotr Pruszczyk, Petar Seferovic, Andrew J S Coats, Marco Metra, Giuseppe Rosano, Stephan Rosenkranz, Carlo Gabriele Tocchetti
Pulmonary hypertension (PH) associated with left heart failure (LHF) (PH-LHF) is one of the most common causes of PH. It directly contributes to symptoms and reduced functional capacity and negatively affects right heart function, ultimately leading to a poor prognosis. There are no specific treatments for PH-LHF, despite the high number of drugs tested so far. This scientific document addresses the main knowledge gaps in PH-LHF with emphasis on pathophysiology and clinical trials. Key identified issues include better understanding of the role of pulmonary venous versus arteriolar remodelling, multidimensional phenotyping to recognize patient subgroups positioned to respond to different therapies, and conduct of rigorous pre-clinical studies combining small and large animal models...
April 19, 2024: European Journal of Heart Failure
#30
JOURNAL ARTICLE
Ting Cong, Rajiv P Reddy, Arielle J Hall, Akhmad Ernazarov, James Gladstone
BACKGROUND: There is no consensus among sports medicine surgeons in North America on postoperative rehabilitation strategy after meniscus repair. Various meniscal tear types may necessitate a unique range of motion (ROM) and weightbearing rehabilitation protocol. PURPOSE: To assess the current landscape of how sports medicine practitioners in the American Orthopedic Society for Sports Medicine (AOSSM) rehabilitate patients after the repair of varying meniscal tears...
February 2024: Orthopaedic Journal of Sports Medicine
#31
JOURNAL ARTICLE
Katharina Lechner, Sylvia Kia, Pia von Korn, Sophia M Dinges, Stephan Mueller, Arnt-Erik Tjønna, Ulrik Wisløff, Emeline M Van Craenenbroeck, Burkert Pieske, Volker Adams, Axel Pressler, Ulf Landmesser, Martin Halle, Nicolle Kränkel
BACKGROUND: Metabolic syndrome (MetS) is defined by the presence of central obesity plus ≥two metabolic/cardiovascular risk factors (RF), with inflammation being a major disease-driving mechanism. Structured endurance exercise training (ET) may positively affect these traits, as well as cardiorespiratory fitness (V̇O2 peak). AIMS: We explore individual ET-mediated improvements of MetS-associated RF in relation to improvements in V̇O2 peak and inflammatory profile...
2024: Frontiers in Cardiovascular Medicine
#32
JOURNAL ARTICLE
Faouzia Tayari, Kais Iben Nassar, Saja Algessair, Mokhtar Hjiri, Majdi Benamara
This study investigates the characteristics of the Ba0.67 Ni0.33 Mn1- x Fe x O3 perovskite compound, focusing on its structural and electrical aspects under varying Fe doping levels at the Mn-site ( x = 0, 0.2). X-ray diffraction patterns confirm the material's consistent structure, with Fe3+ ions substituting Mn3+ ions while maintaining their identical ionic radius. Nano-crystallinity studies reveal single-phase crystallization in the orthorhombic structure with space group Imma . Samples are prepared through conventional solid-state sintering...
April 16, 2024: RSC Advances
#33
JOURNAL ARTICLE
Amy Acker, Kirk Leifso, Lindsay Crawford, Heather Braund, Emily Hawksby, Andrew K Hall, Laura McEwen, Nancy Dalgarno, Jeffrey Damon Dagnone
OBJECTIVES: In 2017, Queen's University launched Competency-Based Medical Education (CBME) across 29 programs simultaneously. Two years post-implementation, we asked key stakeholders (faculty, residents, and program leaders) within the Pediatrics program for their perspectives on and experiences with CBME so far. METHODS: Program leadership explicitly described the intended outcomes of implementing CBME. Focus groups and interviews were conducted with all stakeholders to describe the enacted implementation...
December 2023: Paediatrics & Child Health
#34
MULTICENTER STUDY
Michael D Keller, Patrick J Hanley, Yueh-Yun Chi, Paibel Aguayo-Hiraldo, Christopher C Dvorak, Michael R Verneris, Donald B Kohn, Sung-Yun Pai, Blachy J Dávila Saldaña, Benjamin Hanisch, Troy C Quigg, Roberta H Adams, Ann Dahlberg, Shanmuganathan Chandrakasan, Hasibul Hasan, Jemily Malvar, Mariah A Jensen-Wachspress, Christopher A Lazarski, Gelina Sani, John M Idso, Haili Lang, Pamela Chansky, Chase D McCann, Jay Tanna, Allistair A Abraham, Jennifer L Webb, Abeer Shibli, Amy K Keating, Prakash Satwani, Pawel Muranski, Erin Hall, Michael J Eckrich, Evan Shereck, Holly Miller, Ewelina Mamcarz, Rajni Agarwal, Satiro N De Oliveira, Mark T Vander Lugt, Christen L Ebens, Victor M Aquino, Jeffrey J Bednarski, Julia Chu, Suhag Parikh, Jennifer Whangbo, Michail Lionakis, Elias T Zambidis, Elizabeth Gourdine, Catherine M Bollard, Michael A Pulsipher
Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of refractory viral infections in prior studies. We performed a phase II multicenter study (NCT03475212) for the treatment of pediatric patients with inborn errors of immunity and/or post allogeneic hematopoietic stem cell transplant with refractory viral infections using partially-HLA matched VSTs targeting cytomegalovirus, Epstein-Barr virus, or adenovirus...
April 18, 2024: Nature Communications
#35
JOURNAL ARTICLE
Peter Calvert, Wern Yew Ding, Mark T Mills, Richard Snowdon, Zoltan Borbas, Simon Modi, Mark Hall, Maureen Morgan, Nichola Clarkson, Sijimole Chackochen, Janet Barton, Ian Kemp, Vishal Luther, Dhiraj Gupta
BACKGROUND: No study has assessed durability of pulmonary vein isolation (PVI) with radiofrequency (RF) and Cryoballoon (CB) in patients with persistent AF. These data are especially lacking for those with significantly diseased left atria (LA). OBJECTIVE: To assess PVI durability in patients with significant LA disease and compare reconnection rates between RF and CB. METHODS: 44 Patients (mean age 63, 77% male, median time since AF diagnosis 22...
April 16, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#36
JOURNAL ARTICLE
Jodi J L Rowley, Andrew Symons, Christopher Doyle, Jane Hall, Karrie Rose, Laura Stapp, Damian C Lettoof
Pesticide contamination poses a significant threat to non-target wildlife, including amphibians, many of which are already highly threatened. This study aims to assess the extent of pesticide exposure in dead frogs collected during a mass mortality event across eastern New South Wales, Australia between July 2021 and March 2022. Liver tissue from 77 individual frogs of six species were analysed for >600 legacy and contemporary pesticides, including rodenticides. More than a third (36 %) of the liver samples contained at least one pesticide, including brodifacoum, dieldrin, DDE, heptachlor/heptachlor epoxide, fipronil sulfone, and 2-methyl-4-chlorophenoxyacetic acid (MCPA)...
April 16, 2024: Science of the Total Environment
#37
JOURNAL ARTICLE
Priscilla Viana da Silva, Steven J Kamper, Alix Hall, Tie P Yamato, Lise Hestbaek, Henrik H Lauridsen, Christopher M Williams
BACKGROUND: Despite the high prevalence of musculoskeletal (MSK) pain in children, there is a lack of instruments to measure the impact of MSK pain on children's activity and participation. OBJECTIVE: To assess the reliability and construct validity of the Pediatric MSK Pain Impact summary score in school children (aged 9 to 12) with MSK pain. METHODS: We used a pragmatic approach in a reflective framework to assess internal consistency, structural validity, convergent validity, and discriminative validity in a sample of 615 children with MSK pain...
March 23, 2024: Brazilian Journal of Physical Therapy
#38
JOURNAL ARTICLE
Mallory M Przybylski, Daniel T Hall, Laura H Ikuma
The primary objectives of any high-volume surgery department should be patient safety, block time utilization and operating room efficiency. Reducing preparation time in the OR prior to actual surgery can improve operating room efficiency and utilization, but only if patient safety can be maintained. With this goal, this study evaluated a novel skin preparation technique using a device named ULTRAPREP™, a sterile, medical-grade plastic bag that is applied to the upper or lower extremity in the pre-operative holding area which allows for skin disinfection outside the OR (referred to as "disinfection bag")...
April 18, 2024: Surgical Technology International
#39
JOURNAL ARTICLE
Zijie Zhu, Marius Gächter, Anne-Sophie Walter, Konrad Viebahn, Tilman Esslinger
The transport properties of gapless edge modes at boundaries between topologically distinct domains are of fundamental and technological importance. We experimentally studied long-distance quantized Hall drifts in a harmonically confined topological pump of ultracold fermionic atoms. We found that quantized drifts halt and reverse their direction when the atoms reach a critical slope of the confining potential, revealing the presence of a topological boundary. The drift reversal corresponded to a band transfer between a band with Chern number C = +1 and another with C = -1 through a gapless edge mode, in agreement with the bulk-edge correspondence for noninteracting particles...
April 19, 2024: Science
#40
JOURNAL ARTICLE
Van Tuong Pham, Naveen Sisodia, Ilaria Di Manici, Joseba Urrestarazu-Larrañaga, Kaushik Bairagi, Johan Pelloux-Prayer, Rodrigo Guedas, Liliana D Buda-Prejbeanu, Stéphane Auffret, Andrea Locatelli, Tevfik Onur Menteş, Stefania Pizzini, Pawan Kumar, Aurore Finco, Vincent Jacques, Gilles Gaudin, Olivier Boulle
Magnetic skyrmions are topological magnetic textures that hold great promise as nanoscale bits of information in memory and logic devices. Although room-temperature ferromagnetic skyrmions and their current-induced manipulation have been demonstrated, their velocity has been limited to about 100 meters per second. In addition, their dynamics are perturbed by the skyrmion Hall effect, a motion transverse to the current direction caused by the skyrmion topological charge. Here, we show that skyrmions in compensated synthetic antiferromagnets can be moved by current along the current direction at velocities of up to 900 meters per second...
April 19, 2024: Science
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