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https://www.readbyqxmd.com/read/28725445/manual-ventilation-and-open-suction-procedures-contribute-to-negative-pressures-in-a-mechanical-lung-model
#1
Espen Rostrup Nakstad, Helge Opdahl, Fridtjof Heyerdahl, Fredrik Borchsenius, Ole Henning Skjønsberg
INTRODUCTION: Removal of pulmonary secretions in mechanically ventilated patients usually requires suction with closed catheter systems or flexible bronchoscopes. Manual ventilation is occasionally performed during such procedures if clinicians suspect inadequate ventilation. Suctioning can also be performed with the ventilator entirely disconnected from the endotracheal tube (ETT). The aim of this study was to investigate if these two procedures generate negative airway pressures, which may contribute to atelectasis...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28723339/bronchoscopic-removal-of-an-obstructing-broncholith
#2
Kathryn Williams, Karen Swanson
A 68-year-old woman presented to the emergency department with a 3-day history of worsening shortness of breath, wheezing, dry cough, fevers, and chills. Her oxygen saturation was 96% while she was breathing ambient air. Pulmonary examination revealed crackles in the left lower lobe. Computed..
July 20, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28723308/percutaneous-trans-tracheal-endoscopic-approach-a-novel-technique-for-the-excision-of-benign-lesions-of-thoracic-trachea
#3
Suresh C Sharma, K Devaraja, Arvind Kairo, Rakesh Kumar
INTRODUCTION: Currently, neoplasms of the trachea and lower airway demand open transcervical approach with or without thoracotomy. We describe here a novel, minimally invasive approach for an intraluminal lesion of the thoracic trachea, called percutaneous trans-tracheal endoscopic approach (PTEA). Apart from obvious advantages over potentially morbid open procedures, this technique has certain peculiar benefits over rigid or flexible bronchoscopic approach. MATERIALS AND METHODS: A 43-year-old male patient had glomus tumor of thoracic trachea...
July 19, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28719233/bronchoscopic-management-of-airway-compression-due-to-fibrosing-mediastinitis
#4
Ryan Kern, Tobias Peikert, Eric Edell, John Mullon, David Midthun, James Utz, Fabien Maldonado
No abstract text is available yet for this article.
July 18, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28718101/flexible-bronchoscopic-intubation-through-the-auragain%C3%A2-laryngeal-mask-versus-a-slit-guedel-tube-a-non-inferiority-randomized-controlled-trial
#5
Berthold Moser, Laurent Audigé, Christian Keller, Joseph Brimacombe, Lukas Gasteiger, Heinz R Bruppacher
PURPOSE: AuraGain(TM), a novel third-generation laryngeal mask, can facilitate insertion of a gastric tube and provide the potential advantage of intubation. Data are lacking on intubation through the AuraGain laryngeal mask. METHODS: Eighty-eight hip or knee surgery patients were enrolled in this parallel randomized-controlled trial. We hypothesized that intubation time using the AuraGain laryngeal mask would be no longer than that for standard flexible bronchoscopic intubation over a slit Guedel tube, with a non-inferiority margin of five seconds...
July 17, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28709488/endobronchial-ultrasound-experience-in-a-high-tuberculosis-prevalence-setting
#6
Balamugesh Thangakunam, Barney Thomas Jesudason Isaac, Devasahayam Jesudas Christopher
BACKGROUND: Most of the published endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) data are from the western countries, establishing the role of EBUS-TBNA in the diagnosis and staging of lung cancer. The etiology of mediastinal lymphadenopathy may be different in an ethnic group with a high prevalence of tuberculosis (TB). OBJECTIVE: To assess the etiology of mediastinal adenopathy in a high TB prevalence setting and to determine the performance of various tests in the diagnosis of tuberculous mediastinal lymphadenitis...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28704777/preinvasive-disease-of-the-airway
#7
REVIEW
Ricky M Thakrar, Adam Pennycuick, Elaine Borg, Sam M Janes
Squamous cell carcinoma of the lung arises from preinvasive progenitors in the central airways. The archetypal model appears to be a stepwise morphological progression until there is invasion of the basement membrane. However, not every lesion appears to follow this course and many individuals can have stable disease, or indeed regress to normal epithelium. From our increased understanding of the molecular pathology it is becoming apparent that the respiratory epithelium accumulates progressive genetic and epigenetic insults in response to carcinogens...
July 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28698792/complete-cricotracheal-transection-due-to-blunt-neck-trauma-without-significant-symptoms
#8
Reza Ershadi, Asghar Hajipour, Mohamadrahim Vakili
Laryngotracheal injuries are relatively rare but their mortality rate is fairly high. Complete disruption of trachea is extremely rare and a systematic approach is needed for early diagnosis and favourable outcome. The patients symptoms and physical signs do not necessarily correlate with the severity of the injuries and this case report highlights it. This is a case report of 25-year-old man who arrived to the emergency department 8 h after a motor accident in which a rope was wrapped around his neck. Because of the good general and respiratory condition of the patient on admission, the pathognomonic signs of laryngeal injury were not noticed...
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28697969/childhood-severe-asthma-new-insights-on-remodelling-and-biomarkers
#9
REVIEW
Sejal Saglani
Severe asthma in children is characterised by severe and multiple aeroallergen sensitisation, food allergy, eosinophilic airway inflammation and airway remodelling. However, it is a heterogeneous disease with considerable variability in the manifestation of each of these characteristics between patients. Recent data from mechanistic studies that have used translational approaches including neonatal mouse models and airway bronchoscopic samples, have shown specific molecular mediators that drive remodelling and steroid resistance in paediatric severe asthma will be discussed...
June 12, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28697892/bronchopleural-fistula-after-pneumonectomy-risk-factors-and-management-focusing-on-open-window-thoracostomy
#10
Antonio Mazzella, Alessandro Pardolesi, Patrick Maisonneuve, Francesco Petrella, Domenico Galetta, Roberto Gasparri, Lorenzo Spaggiari
OBJECTIVE: To evaluate principal risk factors and different therapeutic approaches for postpneumonectomy bronchopleural fistula (BPF), focusing on open window thoracostomy (OWT). METHODS: We retrospectively reviewed all patients treated by pneumonectomy for lung cancer between 1999 and 2014. We evaluated preoperative, operative, and postoperative data; interval between operation and fistula formation; and size, treatment, and predicting factors of BPF. Cumulative incidence curves for the development of BPF were drawn according to the Kaplan-Meier method...
June 12, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28683443/navigation-bronchoscopy-guided-radiofrequency-ablation-for-nonsurgical-peripheral-pulmonary-tumors
#11
Fangfang Xie, Xiaoxuan Zheng, Bo Xiao, Baohui Han, Felix J F Herth, Jiayuan Sun
We have recently developed a flexible catheter electrode used for bronchoscopic radiofrequency ablation (RFA). Two patients with nonsurgical stage IA peripheral lung cancer and 1 with lung metastasis underwent treatment with flexible catheter RFA utilizing navigation bronchoscopy. Chest computed tomography (CT) and positron emission tomography/CT (PET/CT) were performed before and after RFA to assess the ablation response of the patients. One patient's tumor had no prior PET uptake and therefore no follow-up PET was obtained...
July 6, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28682836/a-technique-of-awake-bronchoscopic-endotracheal-intubation-for-respiratory-failure-in-patients-with-right-heart-failure-and-pulmonary-hypertension
#12
Jimmy Johannes, David A Berlin, Parimal Patel, Edward J Schenck, Frances Mae West, Rajan Saggar, Igor Z Barjaktarevic
OBJECTIVE: Patients with pulmonary hypertension and right heart failure have a high risk of clinical deterioration and death during or soon after endotracheal intubation. The effects of sedation, hypoxia, hypoventilation, and changes in intrathoracic pressure can lead to severe hemodynamic instability. In search for safer approach to endotracheal intubation in this cohort of patients, we evaluate the safety and feasibility of an alternative intubation technique. DATA SOURCES: Retrospective data analysis...
July 4, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28678769/value-of-endobronchial-ultrasound-elastography-in-diagnosis-of-central-lung-lesions
#13
Hai-Yan He, Jin-Liang Chen, Hang Ma, Jie Zhu, Dan-Dan Wu, Xue-Dong Lv
BACKGROUND Ultrasound elastography is an imaging modality used to show tissue stiffness in tumor pathophysiological processes that promote the formation of stiffer tissues. Endobronchial ultrasound (EBUS) elastography is an ultrasound elastography-based technique for measuring tissue stiffness during EBUS-guided transbronchial needle aspiration (EBUS-TBNA). The diagnostic value of EBUS elastography in central lung lesions remains largely unknown. MATERIAL AND METHODS A total of 57 patients with central lung lesions underwent ultrasonic bronchoscope examination...
July 5, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28676053/bronchial-thermoplasty-activations-predict-response
#14
David Langton, Joy Sha, Alvin Ing, David Fielding, Francis Thien, Virginia Plummer
BACKGROUND: Bronchial thermoplasty (BT) is an emerging bronchoscopic intervention for the treatment of severe asthma. The predictive factors for clinical response to BT are unknown. We examined the relationship between the number of radiofrequency activations applied and the treatment response observed. METHODS: Data were collected from 24 consecutive cases treated at three Australian centres from June 2014 to March 2016. The baseline characteristics were collated along with the activations delivered...
July 4, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28675890/acute-radiological-abnormalities-after-bronchial-thermoplasty-a-prospective-cohort-trial
#15
Julia N S d'Hooghe, Inge A H van den Berk, Jouke T Annema, Peter I Bonta
BACKGROUND: Bronchial thermoplasty (BT) is a novel treatment for severe asthma based on radiofrequency energy delivery to the larger airways. Although impressive radiological abnormalities have been reported, the incidence, pattern, and behavior over time of acute radiological abnormalities following BT are not well established. OBJECTIVE: To assess the incidence pattern and behavior over time of acute radiological abnormalities following BT. METHODS: This is a prospective, observational imaging study of severe asthma patients participating in the TASMA trial...
July 5, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28672965/endobronchial-aspergilloma-a-case-report-and-literature-review
#16
Dongdong Huang, Bing Li, Haiqing Chu, Zhemin Zhang, Qiuhong Sun, Lan Zhao, Liyun Xu, Li Shen, Tao Gui, Huikang Xie, Jun Zhang
The present study aimed to investigate the clinical and radiological characteristics in addition to the bronchoscopic appearance in patients with endobronchial aspergilloma (EBA). Clinical and radiological characteristics were analyzed alongside the bronchoscopic appearance in 17 patients with EBA diagnosed by bronchoscopy with histological examination. The present study assessed the relevant literature and 13 males and 4 females were included in the comparison, with a median age of 59. Associated diseases included 8 previous diagnoses of pulmonary tuberculosis (47...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28671175/a-rare-cause-of-ventilatory-failure-in-a-patient-with-post-traumatic-intracranial-hemorrhage
#17
Balamugesh Thangakunam, Shakti Kumar Bal, Ajay V Venkatapathy, Aparna Irodi, Devasahayam Jesudas Christopher
High minute ventilation is required to lower intracranial pressures in patients with intracranial bleed. Respiratory acidemia consequent to ventilatory difficulty is dangerous in such patients as it further raises intracranial tension. We describe such a case. A 24-year-old man had to be intubated and mechanically ventilated after he met with a road traffic accident and sustained extensive maxillofacial injuries and intracranial bleed. A tooth was accidentally aspirated in this injury and progressively resulted in left lower lobe collapse, pneumomediastinum, and consequent difficult ventilation...
July 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28667653/occurrence-of-bronchial-anthracofibrosis-in-respiratory-symptomatics-with-exposure-to-biomass-fuel-smoke
#18
Vikas Pilaniya, Shekhar Kunal, Ashok Shah
INTRODUCTION: Bronchial anthracofibrosis (BAF), confirmed bronchoscopically, is characterised by bluish-black mucosal pigmentation and distortion/narrowing of the bronchus. We investigated the occurrence of BAF in respiratory symptomatics with biomass fuel smoke exposure and evaluated its clinico-radiological attributes and impact on functional status. MATERIAL AND METHODS: Of the eighty subjects evaluated, 60 consented for fiberoptic bronchoscopy (FOB). All 60 subjects also underwent chest radiography, high resolution computed tomography (HRCT) of the thorax, complete pulmonary function testing including diffusion capacity and six-minute-walk test...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28663790/recent-advances-in-the-management-of-chronic-obstructive-pulmonary-disease
#19
REVIEW
Sharon R Rosenberg, Ravi Kalhan
Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD). Emerging data question the role of inhaled corticosteroids in COPD treatment, particularly as combination dual bronchodilator pharmacotherapies demonstrate robust results. For those maximized on pharmacotherapy with continued dyspnea or exacerbations or both, emerging bronchoscopic procedures may offer additional therapy in select patients. This review focuses on data supporting the use of novel ultra bronchodilators, particularly in combination, and on the role for inhaled corticosteroid withdrawal and new bronchoscopic procedures...
2017: F1000Research
https://www.readbyqxmd.com/read/28663626/proseal-laryngeal-mask-airway-placement-a-comparison-of-blind-versus-direct-laryngoscopic-insertion-techniques
#20
Pooja Chandrakanth Patil, Manjunath Abloodu Chikkapillappa, Vinayak Seenappa Pujara, Tejesh Channasandra Anandswamy, Leena Harshad Parate, Yatish Bevinaguddaiah
BACKGROUND AND OBJECTIVES: The laryngeal mask airway (LMA) ProSeal is most commonly used supraglottic airway device; it is routinely inserted by blind technique. Although blind insertion technique is most widely used, there are many techniques which are available such as priming the drain tube with a guiding instrument such as a suction catheter, a gum elastic bougie, a Flexi-Slip Stylet, direct laryngoscopy, and even a fiber-optic bronchoscope (FOB). The present study was undertaken to compare and assess the placement of LMA ProSeal using blind versus direct laryngoscopy techniques using FOB...
April 2017: Anesthesia, Essays and Researches
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