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https://www.readbyqxmd.com/read/29780028/induced-endometrial-trauma-endometrial-scratch-in-the-mid-luteal-menstrual-cycle-phase-preceding-first-cycle-ivf-icsi-versus-usual-ivf-icsi-therapy-study-protocol-for-a-randomised-controlled-trial
#1
Clare Pye, Robin Chatters, Judith Cohen, Kate Brian, Ying C Cheong, Susan Laird, Lamiya Mohiyiddeen, Jonathan Skull, Stephen Walters, Tracey Young, Mostafa Metwally
INTRODUCTION: Endometrial trauma commonly known as endometrial scratch (ES) has been shown to improve pregnancy rates in women with a history of repeated implantation failure undergoing in vitro fertilisation (IVF), with or without intracytoplasmic sperm injection (ICSI). However, the procedure has not yet been fully explored in women having IVF/ICSI for the first time. This study aims to examine the effect of performing an ES in the mid-luteal phase prior to a first-time IVF/ICSI cycle on the chances of achieving a clinical pregnancy and live birth...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29779401/evaluating-quantity-and-quality-of-literature-focusing-on-health-economics-and-pharmacoeconomics-in-gulf-cooperation-council-countries
#2
Islam Eljilany, Faris El-Dahiyat, Louise Elizabeth Curley, Zaheer-Ud-Din Babar
BACKGROUND: The importance of pharmacoeconomics and health economics has been augmented. It has the potential to provide evidence to aid in optimal decision-making in the funding of cost-effective medicines and services in Gulf Cooperation Council countries (G.C.C). OBJECTIVE: To evaluate the quality and quantity of health economic research published until the end of 2017 in G.C.C. METHOD: Studies were included according to inclusion and exclusion criteria...
May 19, 2018: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29778396/how-effective-are-approaches-to-migrant-screening-for-infectious-diseases-in-europe-a-systematic-review
#3
REVIEW
Farah Seedat, Sally Hargreaves, Laura B Nellums, Jing Ouyang, Michael Brown, Jon S Friedland
Rates of migration to Europe, and within Europe, have increased in recent years, with considerable implications for health systems. Migrants in Europe face a disproportionate burden of tuberculosis, HIV, and hepatitis B and C, yet experience a large number of barriers to accessing statutory health care on arrival. A better understanding of how to deliver effective and cost-effective screening, vaccination, and health services to this group is now crucial. We did a systematic review to document and assess the effectiveness and cost-effectiveness of approaches used for infectious diseases screening, and to explore facilitators and barriers experienced by migrants to accessing screening programmes...
May 16, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29773075/does-multidisciplinary-rehabilitation-of-tortured-refugees-represent-value-for-money-a-follow-up-of-a-danish-case-study
#4
Line Bager, Kristian Schultz Hansen, Carit Jacques Andersen, Shr-Jie Sharlenna Wang
BACKGROUND: The recent surge of asylum seekers in the European Union (EU) is raising questions about the EU's ability to integrate newcomers into the economy and into society; particularly those who need specialized services for the treatment of severe trauma. This study investigated whether rehabilitating traumatised refugees represents 'value-for-money' (VfM) in terms of intervention cost per health gain and in a long-term and societal perspective. METHODS: The economic evaluation comprised a cost-utility analysis (CUA) and a partial cost-benefit analysis (CBA)...
May 18, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29770210/identification-of-publicly-available-data-sources-to-inform-the-conduct-of-health-technology-assessment-in-india
#5
Laura Downey, Neethi Rao, Lorna Guinness, Miqdad Asaria, Shankar Prinja, Anju Sinha, Rajni Kant, Arvind Pandey, Francoise Cluzeau, Kalipso Chalkidou
Background: Health technology assessment (HTA) provides a globally-accepted and structured approach to synthesising evidence for cost and clinical effectiveness alongside ethical and equity considerations to inform evidence-based priorities. India is one of the most recent countries to formally commit to institutionalising HTA as an integral component of the heath resource allocation decision-making process. The effective conduct of HTA depends on the availability of reliable data.   Methods : We draw from our experience of collecting, synthesizing, and analysing health-related datasets in India and internationally, to highlight the complex requirements for undertaking HTA, and explore the availability of such data in India...
2018: F1000Research
https://www.readbyqxmd.com/read/29769056/report-on-an-international-workshop-on-kangaroo-mother-care-lessons-learned-and-a-vision-for-the-future
#6
Adriano Cattaneo, Adidja Amani, Nathalie Charpak, Socorro De Leon-Mendoza, Sarah Moxon, Somashekhar Nimbalkar, Giorgio Tamburlini, Julieta Villegas, Anne-Marie Bergh
BACKGROUND: Globally, complications of prematurity are the leading cause of death in children under five. Preterm infants who survive their first month of life are at greater risk for various diseases and impairments in infancy, childhood and later life, representing a heavy social and economic burden for families, communities and health and social systems. Kangaroo mother care (KMC) is recommended as a beneficial and effective intervention for improving short- and long-term preterm birth outcomes in low- and high-income settings...
May 16, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29764876/integrated-versus-non-integrated-peripheral-intravenous-catheter-which-is-the-most-effective-system-for-peripheral-intravenous-catheter-management-the-optimum-study-a-randomised-controlled-trial-protocol
#7
Maria Isabel Castillo, Emily Larsen, Marie Cooke, Nicole M Marsh, Marianne C Wallis, Julie Finucane, Peter Brown, Gabor Mihala, Peter J Carr, Joshua Byrnes, Rachel Walker, Prudence Cable, Li Zhang, Candi Sear, Gavin Jackson, Anna Rowsome, Alison Ryan, Julie C Humphries, Susan Sivyer, Kathy Flanigan, Claire M Rickard
INTRODUCTION: Peripheral intravenous catheters (PIVCs) are frequently used in hospitals. However, PIVC complications are common, with failures leading to treatment delays, additional procedures, patient pain and discomfort, increased clinician workload and substantially increased healthcare costs. Recent evidence suggests integrated PIVC systems may be more effective than traditional non-integrated PIVC systems in reducing phlebitis, infiltration and costs and increasing functional dwell time...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29761488/psychological-therapies-for-treatment-resistant-depression-in-adults
#8
REVIEW
Sharea Ijaz, Philippa Davies, Catherine J Williams, David Kessler, Glyn Lewis, Nicola Wiles
BACKGROUND: Antidepressants are a first-line treatment for adults with moderate to severe major depression. However, many people prescribed antidepressants for depression don't respond fully to such medication, and little evidence is available to inform the most appropriate 'next step' treatment for such patients, who may be referred to as having treatment-resistant depression (TRD). National Institute for Health and Care Excellence (NICE) guidance suggests that the 'next step' for those who do not respond to antidepressants may include a change in the dose or type of antidepressant medication, the addition of another medication, or the start of psychotherapy...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29758575/-descriptive-analysis-of-health-economics-of-intensive-home-care-of-ventilated-patients
#9
Yvonne Lehmann, Julia Ostermann, Thomas Reinhold, Michael Ewers
INTRODUCTION: Long-term ventilated patients in Germany receive intensive care mainly in the patients' home or in assisted-living facilities. There is a lack of knowledge about the nature and extent of resource use and costs associated with care of this small, heterogeneous but overall growing patient group. METHODS: A sub-study in the context of a research project SHAPE analyzed costs of 29 patients descriptively from a social perspective. Direct and indirect costs of intensive home care over a period of three months were recorded and analyzed retrospectively...
May 14, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29726749/international-variation-in-programmes-for-assessment-of-children-s-neurodevelopment-in-the-community-understanding-disparate-approaches-to-evaluation-of-motor-social-emotional-behavioural-and-cognitive-function
#10
Philip Wilson, Rachael Wood, Kirsten Lykke, Anette Hauskov Graungaard, Ruth Kirk Ertmann, Merethe Kirstine Andersen, Ole Rikard Haavet, Per Lagerløv, Eirik Abildsnes, Mina P Dahli, Marjukka Mäkelä, Aleksi Varinen, Merja Hietanen
BACKGROUND: Few areas of medicine demonstrate such international divergence as child development screening and surveillance. Many countries have nationally mandated surveillance policies, but the content of programmes and mechanisms for delivery vary enormously. The cost of programmes is substantial but no economic evaluations have been carried out. We have critically examined the history, underlying philosophy, content and delivery of programmes for child development assessment in five countries with comprehensive publicly funded health services (Denmark, Finland, Norway, Scotland and Sweden)...
May 1, 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29722869/screwworm-diptera-calliphoridae-in-the-united-states-response-to-and-elimination-of-the-2016-2017-outbreak-in-florida
#11
Steven R Skoda, Pamela L Phillips, John B Welch
Eradicating screwworm, Cochliomyia hominivorax (Coquerel), from continental North American via the sterile insect technique has provided huge economic benefit to livestock producers by eliminating screwworm myiasis. After confirmatory identification of fly samples from infested deer by the USDA National Veterinary Services Laboratory on September 30, 2016, an alert was issued that screwworm myiasis was discovered in the Florida Keys. Personnel from USDA Animal and Plant Health Inspection Service, Agricultural Research Service, the State of Florida, U...
May 2, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29717978/self-sampling-kits-to-increase-hiv-testing-among-black-africans-in-the-uk-the-haus-mixed-methods-study
#12
Maureen Seguin, Catherine Dodds, Esther Mugweni, Lisa McDaid, Paul Flowers, Sonali Wayal, Ella Zomer, Peter Weatherburn, Ibidun Fakoya, Thomas Hartney, Lorraine McDonagh, Rachael Hunter, Ingrid Young, Shabana Khan, Nick Freemantle, Jabulani Chwaula, Memory Sachikonye, Jane Anderson, Surinder Singh, Eleni Nastouli, Greta Rait, Fiona Burns
BACKGROUND: Timely diagnosis of human immunodeficiency virus (HIV) enables access to antiretroviral treatment, which reduces mortality, morbidity and further transmission in people living with HIV. In the UK, late diagnosis among black African people persists. Novel methods to enhance HIV testing in this population are needed. OBJECTIVES: To develop a self-sampling kit (SSK) intervention to increase HIV testing among black Africans, using existing community and health-care settings (stage 1) and to assess the feasibility for a Phase III evaluation (stage 2)...
April 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29713494/developing-and-feasibility-testing-of-data-collection-methods-for-an-economic-evaluation-of-a-supported-selfmanagement-programme-for-adults-with-a-learning-disability-and-type-2-diabetes
#13
John L O'Dwyer, Amy M Russell, Louise D Bryant, Rebecca E A Walwyn, Alexandra M Wright-Hughes, Elizabeth H Graham, Judy M Wright, Shaista Meer, Jacqueline Birtwistle, Amanda J Farrin, Allan O House, Claire T Hulme
Background: The challenges of conducting research with hard to reach vulnerable groups are particularly pertinent for people with learning disabilities. Data collection methods for previous cost and cost-effectiveness analyses of health and social care interventions targeting people with learning disabilities have relied on health care/health insurance records or data collection forms completed by the service provider rather than by people with learning disabilities themselves. This paper reports on the development and testing of data collection methods for an economic evaluation within a randomised controlled trial (RCT) for a supported self-management programme for people with mild/moderate learning disabilities and type 2 diabetes...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29709055/interventions-for-investigating-and-identifying-the-causes-of-stillbirth
#14
REVIEW
Aleena M Wojcieszek, Emily Shepherd, Philippa Middleton, Glenn Gardener, David A Ellwood, Elizabeth M McClure, Katherine J Gold, Teck Yee Khong, Robert M Silver, Jan Jaap Hm Erwich, Vicki Flenady
BACKGROUND: Identification of the causes of stillbirth is critical to the primary prevention of stillbirth and to the provision of optimal care in subsequent pregnancies. A wide variety of investigations are available, but there is currently no consensus on the optimal approach. Given their cost and potential to add further emotional burden to parents, there is a need to systematically assess the effect of these interventions on outcomes for parents, including psychosocial outcomes, economic costs, and on rates of diagnosis of the causes of stillbirth...
April 30, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29703859/characteristics-of-value-based-health-and-social-care-from-organisations-perspectives-orgvalue-a-mixed-methods-study-protocol
#15
Lena Ansmann, Hendrik Ansgar Hillen, Ludwig Kuntz, Stephanie Stock, Vera Vennedey, Kira Isabelle Hower
INTRODUCTION: Health and social care systems are under pressure to organise care around patients' needs with constrained resources. Several studies reveal that care is constantly challenged by balancing economic requirements against individual patients' preferences and needs. Therefore, value-based health and social care aims to facilitate patient-centredness while taking the resources spent into consideration. The OrgValue project examines the implementation of patient-centredness while considering the health and social care organisations' resource orientation in the model region of the city of Cologne, Germany...
April 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29624704/implementation-science-to-advance-care-delivery-a-primer-for-pharmacists-and-other-health-professionals
#16
Melanie Livet, Stuart T Haines, Geoff M Curran, Terry Seaton, Caryn Ward, Todd Sorensen, Mary Roth McClurg
There is increasing pressure within healthcare to implement evidence-based interventions that improve quality, control costs, and maximize value. Unfortunately, many clinical services and interventions to optimize medication use do not consistently produce the intended humanistic, clinical, and economic outcomes. The lack of conclusive results is believed to stem from the widely recognized research-to-practice gap. The field of implementation science seeks to discover and apply strategies designed to accelerate successful integration of interventions into routine practice...
April 6, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29623624/the-economic-burden-of-small-cell-lung-cancer-a-systematic-review-of-the-literature
#17
REVIEW
Ashley Enstone, Maire Greaney, Manca Povsic, Robin Wyn, John R Penrod, Yong Yuan
BACKGROUND: Small cell lung cancer (SCLC), the most aggressive form of lung carcinoma, represents approximately 15% of all lung cancers; however, the economic and healthcare burden of SCLC is not well-defined. OBJECTIVE: The aim of this study was to explore the impact of SCLC on healthcare costs through a systematic literature review (SLR). METHODS: Using the OVID search engine, the SLR was conducted in PubMed, MEDLINE In-Process, EMBASE, EconLIT and the National Health Service Economic Evaluation Database (NHS EED)...
August 18, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29617884/rituximab-versus-the-modified-ponticelli-regimen-in-the-treatment-of-primary-membranous-nephropathy-a-health-economic-model
#18
Patrick Hamilton, Durga Kanigicherla, Michael Venning, Paul Brenchley, David Meads
Background: Membranous nephropathy is among the most common causes of nephrotic syndrome worldwide, with a high healthcare burden. Treatment using the modified Ponticelli regimen (mPR) has remained the standard of care for decades, but newer therapies such as rituximab offer promising results with reduced side effects. The cost of this treatment, however, is perceived as a barrier to widespread use, especially in resource limited healthcare systems. Methods: We developed a decision-analytic model to estimate the cost-effectiveness of rituximab versus the mPR from the perspective of the National Health Service in the UK over a 1 year, 5 year and lifetime horizon...
March 29, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29614104/structural-barriers-to-hiv-prevention-among-men-who-have-sex-with-men-msm-in-vietnam-diversity-stigma-and-healthcare-access
#19
Morgan M Philbin, Jennifer S Hirsch, Patrick A Wilson, An Thanh Ly, Le Minh Giang, Richard G Parker
Men who have sex with men (MSM) in Vietnam experience disproportionate rates of HIV infection. To advance understanding of how structural barriers may shape their engagement with HIV prevention services, we draw on 32 in-depth interviews and four focus groups (n = 31) conducted with MSM in Hanoi between October 2015- March 2016. Three primary factors emerged: (1) Diversity, both in relation to identity and income; Vietnamese MSM described themselves as segregated into Bóng kín (hidden, often heterosexually-identified MSM) and Bóng lộ ('out,' transgender, or effeminate MSM)...
2018: PloS One
https://www.readbyqxmd.com/read/29611869/contracting-out-to-improve-the-use-of-clinical-health-services-and-health-outcomes-in-low-and-middle-income-countries
#20
REVIEW
Willem A Odendaal, Kim Ward, Jesse Uneke, Henry Uro-Chukwu, Dereck Chitama, Yusentha Balakrishna, Tamara Kredo
BACKGROUND: Contracting out of governmental health services is a financing strategy that governs the way in which public sector funds are used to have services delivered by non-governmental health service providers (NGPs). It represents a contract between the government and an NGP, detailing the mechanisms and conditions by which the latter should provide health care on behalf of the government. Contracting out is intended to improve the delivery and use of healthcare services. This Review updates a Cochrane Review first published in 2009...
April 3, 2018: Cochrane Database of Systematic Reviews
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