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https://www.readbyqxmd.com/read/28331285/refraction-outcomes-after-suction-loss-during-small-incision-lenticule-extraction-smile
#1
Amr A Gab-Alla
PURPOSE: To evaluate refractive outcomes of two management approaches after suction loss during the small-incision lenticule extraction (SMILE) technique. PATIENTS AND METHODS: This retrospective and comparative study was conducted at the El-Gowhara Private Eye Center. It included 26 consecutive eyes of patients who experienced suction loss during the SMILE technique. Patients were divided into two groups by the technical difficulties in redocking: in group A (12 eyes) suction loss occurred after the posterior lenticular cut and the creation of side-cuts, then suction was reapplied, and the procedure was completed; in group B (14 eyes) suction loss occurred after the posterior lenticular cut and the creation of side-cuts, then the procedure was postponed for 24 hours and completed with the same parameters...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28329923/-actinomycosis-involving-chronic-pancreatitis-a-case-report-with-literature-review
#2
Seong Jae Yeo, Chang Min Cho, Min Kyu Jung, Ki Ju Kim, Myung Hi Kim, Seung Hyun Cho, Gab Chul Kim, An Na Seo
Actinomycosis is a slowly progressive, chronic infectious disease. It is caused by the genus Actinomyces, which are gram-positive anaerobic bacteria. It presents as a mass-like lesion, composed of bacterial nidus and characteristic granulomatous inflammatory fibrosis. As such, it has frequently been mistaken for a malignancy. Surgical resection is a common procedure in these patients prior to a definite diagnosis. Although actinomycosis can occur in a variety of regions, including oral-cervicofacial, thoracic, and abdominopelvic cavities, the involvement of the pancreas is very rare...
March 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28328820/long-term-outcomes-of-surgery-alone-versus-surgery-following-preoperative-chemoradiotherapy-for-early-t3-rectal-cancer-a-propensity-score-analysis
#3
Seung Hyun Cho, Gyu-Seog Choi, Gab Chul Kim, An Na Seo, Hye Jung Kim, Won Hwa Kim, Kyung-Min Shin, So Mi Lee, Hunkyu Ryeom, See Hyung Kim
Recently, a few studies have raised the question of whether preoperative chemoradiotherapy (PCRT) is essential for all T3 rectal cancers. This case-matched study aimed to compare the long-term outcomes of surgery alone with those of PCRT + surgery for magnetic resonance imaging (MRI)-assessed T3ab (extramural depth of invasion ≤5 mm) and absent mesorectal fascia invasion (clear MRF) in mid/lower rectal cancer patients.From January 2006 to November 2012, 203 patients who underwent curative surgery alone (n = 118) or PCRT + surgery (n = 85) were enrolled in this retrospective study...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28294293/current-barriers-and-potential-strategies-to-increase-the-use-of-long-acting-reversible-contraception-larc-to-reduce-the-rate-of-unintended-pregnancies-in-australia-an-expert-roundtable-discussion
#4
Danielle Mazza, Deborah Bateson, Meredith Frearson, Philip Goldstone, Gab Kovacs, Rod Baber
BACKGROUND: Australia's abortion rates are among the highest in the developed world. Efficacy of the most commonly used form of contraception (oral contraceptives and condoms) relies on regular user compliance. Long-acting reversible contraception (LARC) virtually eradicates contraceptive failure as it is not user-dependent; however, its uptake has been low. AIM: To provide an overview of barriers to LARC use in Australia and potential strategies to overcome these barriers...
March 10, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28289665/clinical-characteristics-of-papillary-thyroid-carcinoma-arising-from-the-pyramidal-lobe
#5
Sang Gab Yoon, Jin Wook Yi, Chan-Yong Seong, Jong-Kyu Kim, Su-Jin Kim, Young Jun Chai, June Young Choi, Kyu Eun Lee
PURPOSE: Papillary thyroid carcinoma (PTC) arising from the pyramidal lobe is rare; therefore, clinicopathologic evaluation is lacking. In addition, the rate of occult malignancy in the pyramidal lobe after thyroid surgery is unclear. This study is to evaluate the clinical characteristics of PTCs that involve the pyramidal lobe. METHODS: The study enrolled 1,107 patients who underwent thyroid surgery for PTC at Seoul National University Hospital from 2006 to 2015...
March 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28285514/fasciola-hepatica-infection-status-of-freshwater-snails-collected-from-gangwon-do-province-korea
#6
Jae-Hyung Lee, Juan-Hua Quan, In-Wook Choi, Gab-Man Park, Guang-Ho Cha, Hyun-Ju Kim, Jae-Min Yuk, Young-Ha Lee
Fasciola hepatica is a trematode that causes zoonosis, mainly in cattle and sheep, and occasionally in humans. Few recent studies have determined the infection status of this fluke in Korea. In August 2015, we collected 402 samples of freshwater snails at Hoenggye-ri (upper stream) and Suha-ri (lower stream) of Song-cheon (stream) in Daegwalnyeong-myeon, Pyeongchang-gun in Gangwon-do (Province) near many large cattle or sheep farms. F. hepatica infection was determined using PCR on the nuclear ribosomal internal transcribed spacer 2 (ITS-2)...
February 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28283911/recovery-of-renal-function-after-administration-of-adipose-tissue-derived-stromal-vascular-fraction-in-rat-model-of-acute-kidney-injury-induced-by-ischemia-reperfusion-injury
#7
Chunwoo Lee, Myoung Jin Jang, Bo Hyun Kim, Jin Young Park, Dalsan You, In Gab Jeong, Jun Hyuk Hong, Choung-Soo Kim
Acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) injury is a major challenge in critical care medicine. The purpose of this study is to determine the therapeutic effects of the adipose-tissue-derived stromal vascular fraction (SVF) and the optimal route for SVF delivery in a rat model of AKI induced by I/R injury. Fifty male Sprague-Dawley rats were randomly divided into five groups (10 animals per group): sham, nephrectomy control, I/R injury control, renal arterial SVF infusion and subcapsular SVF injection...
March 10, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28262724/comparison-of-bone-mineral-loss-by-combined-androgen-block-agonist-versus-gnrh-in-patients-with-prostate-cancer-a-12-month-prospective-observational-study
#8
Sung Han Kim, Jae Young Joung, Sohee Kim, Koon Ho Rha, Hyeong Gon Kim, Cheol Kwak, Ji Youl Lee, Seong Soo Jeon, Sung Kyu Hong, Hyeon Jeong, Moon Ki Jo, Dalsan You, In Gab Jeong, Jun Hyuk Hong, Choung-Soo Kim
The multi-centre, prospective, observational study was designed to examine the efficacy of continuous combined androgen block (CAB) vs. GnRH agonist monotherapy in terms of bone mineral density (BMD) change during 12 months post-androgen deprivation therapy (ADT) in Asian prostate cancer patients. Multiple regression analysis and estimated the 10-year probability of major fractures among the patients with Fracture Risk Assessment Tool were conducted to investigate the underlying factors affecting BMD. Paired t-test to evaluate the change of BMD from baseline to 12 month, and two sample t-test to examine the difference of BMD changes were used between two groups...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28236579/does-ureteral-catheter-insertion-decrease-the-risk-of-urinary-leakage-after-partial-nephrectomy-in-patients-with-renal-cell-carcinoma
#9
Sangjun Yoo, Dalsan You, In Gab Jeong, Cheryn Song, Bumsik Hong, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim
INTRODUCTION: We aimed to evaluate the impact of preoperative ureteral catheter insertion on urinary leakage after partial nephrectomy (PN) in patients with renal cell carcinoma. METHODS: We reviewed the data of 893 patients with renal cell carcinoma who underwent PN and divided them according to ureteral catheter placement. The impact of ureteral catheter placement on postoperative urinary leakage was evaluated by using multivariate analysis. RESULTS: Ureteral catheters were inserted in 397 (44...
February 6, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28161349/obesity-as-a-risk-factor-for-unfavorable-disease-in-low-risk-prostate-cancer-and-its-relationship-with-anatomic-location-of-tumor
#10
In Gab Jeong, Sangjun Yoo, Chunwoo Lee, Myong Kim, Dalsan You, Cheryn Song, Sungchan Park, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim
PURPOSE: To investigate the influence of obesity on unfavorable disease in low-risk prostate cancer eligible for active surveillance and verify the underlying relationship with tumor location. MATERIALS AND METHODS: We analyzed 890 patients with biopsy Gleason score 6 who underwent radical prostatectomy for prostate cancer via multicore (≥12) biopsy at our institution. Unfavorable disease was defined as primary Gleason pattern ≥4 or pathologic stage ≥T3. Multivariate logistic regression analysis was performed to identify factors associated with unfavorable disease...
February 1, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28145654/preserving-renal-function-through-partial-nephrectomy-depends-on-tumor-complexity-in-t1b-renal-tumors
#11
Sangjun Yoo, Dalsan You, In Gab Jeong, Bumsik Hong, Jun Hyuk Hong, Choung Soo Kim, Hanjong Ahn, Cheryn Song
This study aimed to determine patients with T1b renal cell carcinoma (RCC) who could benefit from partial nephrectomy (PN) and method to identify them preoperatively using nephrometry score (NS). From a total of 483 radical nephrectomy (RN)-treated patients and 40 PN-treated patients who received treatment for T1b RCC between 1995 and 2010, 120 patients identified through 1:2 propensity-score matching were included for analysis. Probability of chronic kidney disease (CKD) until postoperative 5-years was calculated and regressed with respect to the surgical method and NS...
March 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28145435/processable-high-internal-phase-pickering-emulsions-using-depletion-attraction
#12
KyuHan Kim, Subeen Kim, Jiheun Ryu, Jiyoon Jeon, Se Gyu Jang, Hyunjun Kim, Dae-Gab Gweon, Won Bin Im, Yosep Han, Hyunjung Kim, Siyoung Q Choi
High internal phase emulsions have been widely used as templates for various porous materials, but special strategies are required to form, in particular, particle-covered ones that have been more difficult to obtain. Here, we report a versatile strategy to produce a stable high internal phase Pickering emulsion by exploiting a depletion interaction between an emulsion droplet and a particle using water-soluble polymers as a depletant. This attractive interaction facilitating the adsorption of particles onto the droplet interface and simultaneously suppressing desorption once adsorbed...
February 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28139370/lymph-node-density-vs-the-american-joint-committee-on-cancer-tnm-nodal-staging-system-in-node-positive-bladder-cancer-in-patients-undergoing-extended-or-super-extended-pelvic-lymphadenectomy
#13
Donghyun Lee, Sangjun Yoo, Dalsan You, Bumsik Hong, Yong Mee Cho, Jun Hyuk Hong, Choung-Soo Kim, Hanjonh Ahn, Jae Y Ro, In Gab Jeong
PURPOSE: We compared the prognostic value of the American Joint Committee on Cancer (AJCC) TNM nodal staging system with that of lymph node (LN) density in patients with LN-positive bladder cancer who received extended or super-extended pelvic lymphadenectomy. METHODS: Of the 1,018 patients, who underwent radical cystectomy and pelvic lymphadenectomy between February 2005 and August 2014, 110 patients with LN metastases with extended (n = 68) or super-extended (n = 42) pelvic lymphadenectomy were included...
January 27, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28115166/gab3-is-required-for-human-colorectal-cancer-cell-proliferation
#14
Shihao Xiang, Na Wang, Pingping Hui, Jiali Ma
Here, we focused on the potential function of Gab3, an uncommon Gab family protein, in human colorectal cancer (CRC) cells. We found that Gab3 was only expressed in human colon cancer tissues as well as in established (HCT-116 and HT-29 lines) and primary human CRC cells. It was however absent in normal human colon cancer tissues and in FHC colon epithelial cells. Knockdown of Gab3 by targeted-shRNAs inhibited proliferation of the CRC cells. Reversely, exogenous over-expression of Gab3 promoted CRC cell proliferation...
January 20, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28111189/mapping-the-critical-gestational-age-at-birth-that-alters-brain-development-in-preterm-born-infants-using-multi-modal-mri
#15
Dan Wu, Linda Chang, Kentaro Akazawa, Kumiko Oishi, Jon Skranes, Thomas Ernst, Kenichi Oishi
Preterm birth adversely affects postnatal brain development. In order to investigate the critical gestational age at birth (GAB) that alters the developmental trajectory of gray and white matter structures in the brain, we investigated diffusion tensor and quantitative T2 mapping data in 43 term-born and 43 preterm-born infants. A novel multivariate linear model-the change point model, was applied to detect change points in fractional anisotropy, mean diffusivity, and T2 relaxation time. Change points captured the "critical" GAB value associated with a change in the linear relation between GAB and MRI measures...
January 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/28068921/co-localization-of-major-quantitative-trait-loci-for-pod-size-and-weight-to-a-3-7%C3%A2-cm-interval-on-chromosome-a05-in-cultivated-peanut-arachis-hypogaea-l
#16
Huaiyong Luo, Xiaoping Ren, Zhendong Li, Zhijun Xu, Xinping Li, Li Huang, Xiaojing Zhou, Yuning Chen, Weigang Chen, Yong Lei, Boshou Liao, Manish K Pandey, Rajeev K Varshney, Baozhu Guo, Xiangguo Jiang, Fei Liu, Huifang Jiang
BACKGROUND: Cultivated peanut (Arachis hypogaea L.), an important source of edible oil and protein, is widely grown in tropical and subtropical areas of the world. Genetic improvement of yield-related traits is essential for improving yield potential of new peanut varieties. Genomics-assisted breeding (GAB) can accelerate the process of genetic improvement but requires linked markers for the traits of interest. In this context, we developed a recombinant inbred line (RIL) mapping population (Yuanza 9102 × Xuzhou 68-4) with 195 individuals and used to map quantitative trait loci (QTLs) associated with three important pod features, namely pod length, pod width and hundred-pod weight...
January 9, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28027398/physiologically-based-pharmacokinetic-predictions-of-intestinal-bcrp-mediated-effect-of-telmisartan-on-the-pharmacokinetics-of-rosuvastatin-in-humans
#17
Soo Hyeon Bae, Wan-Su Park, Seunghoon Han, Gab-Jin Park, Jongtae Lee, Taegon Hong, Sangil Jeon, Dong-Seok Yim
It was recently reported that the Cmax and AUC of rosuvastatin increases when it is coadministered with telmisartan. The aim of this study was to explore the mechanism of the interaction of telmisartan and rosuvastatin. A full-PBPK model of telmisartan was developed, and the rosuvastatin model in Simcyp (version 15)'s drug library was modified to reflect ethnic differences in rosuvastatin exposure. PK characteristics, including intestinal and hepatic transporter / enzyme specificities of telmisartan and rosuvastatin, were incorporated into the PBPK models to simulate a rosuvastatin (20 mg) - telmisartan (80 mg) multiple dose drug interaction study...
December 27, 2016: Biopharmaceutics & Drug Disposition
https://www.readbyqxmd.com/read/27989785/prognostic-value-of-vascular-endothelial-growth-factor-vegf-vegf-receptor-2-platelet-derived-growth-factor-%C3%AE-pdgf-%C3%AE-and-pdgf-%C3%AE-receptor-expression-in-papillary-renal-cell-carcinoma
#18
Myong Kim, Mooyoung Sohn, Myungsun Shim, Seung-Kwon Choi, Myungchan Park, Eunna Kim, Heounjeong Go, Yangsoon Park, Yong Mee Cho, Jae Y Ro, In Gab Jeong, Cheryn Song, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn
The Prognostic value of the expression of vascular endothelial growth factor (VEGF), VEGF receptor 2 (VEGFR2), platelet-derived growth factor (PDGF)-β, and PDGF receptor (PDGFR)-β in papillary renal cell carcinoma (pRCC) is unknown. A total of 145 patients, who were confirmed to have pRCC, were analyzed. Expression levels of molecular markers were assessed via immunohistochemistry. The median follow-up period for all patients was 52.0 (interquartile range, 34.5-90.5) months. Among the cohort of 145 patients, high VEGF expression was observed in 100 (69...
December 15, 2016: Human Pathology
https://www.readbyqxmd.com/read/27979124/application-of-cashew-tree-gum-on-the-production-and-stability-of-spray-dried-fish-oil
#19
Diego Alvarenga Botrel, Soraia Vilela Borges, Regiane Victória de Barros Fernandes, Rosemar Antoniassi, Adelia Ferreira de Faria-Machado, Judith Pessoa de Andrade Feitosa, Regina Celia Monteiro de Paula
Evaluation of cashew gum compared to conventional materials was conducted regarding properties and oxidative stability of spray-dried fish oil. Emulsions produced with cashew gum showed lower viscosity when compared to Arabic gum. The particle size was larger (29.9μm) when cashew gum was used, and the encapsulation efficiency reached 76%, similar to that of modified starch but higher than that for Arabic gum (60%). The oxidation process for the surface oil was conducted and a relative lower formation of oxidation compounds was observed for the cashew gum treatment...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27874078/glutamate-dehydrogenase-activator-bch-stimulating-reductive-amination-prevents-high-fat-high-fructose-diet-induced-steatohepatitis-and-hyperglycemia-in-c57bl-6j-mice
#20
Seung Jin Han, Sung-E Choi, Sang-A Yi, Jong Gab Jung, Ik-Rak Jung, Maureen Shin, Seok Kang, Hyunhee Oh, Hae Jin Kim, Dae Jung Kim, Ji Eun Kwon, Cheol Soo Choi, Kwan Woo Lee, Yup Kang
Individuals with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) induced by high calorie western diet are characterized by enhanced lipogenesis and gluconeogenesis in the liver. Stimulation of reductive amination may shift tricarboxylic acid cycle metabolism for lipogenesis and gluconeogenesis toward glutamate synthesis with increase of NAD+/NADH ratio and thus, ameliorate high calorie diet-induced fatty liver and hyperglycemia. Stimulation of reductive amination through glutamate dehydrogenase (GDH) activator 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH) reduced both de novo lipogenesis and gluconeogenesis but increased the activities of sirtuins and AMP-activated kinase in primary hepatocytes...
November 22, 2016: Scientific Reports
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