keyword
https://read.qxmd.com/read/38628421/disease-burden-clinical-outcomes-and-quality-of-life-in-people-with-hemophilia-a-without-inhibitors-in-europe-analyses-from-chess-ii-chess-paeds
#21
JOURNAL ARTICLE
Pratima Chowdary, Richard Ofori-Asenso, Francis Nissen, Enrico F Grazzi, Martynas Aizenas, Katya Moreno, Tom Burke, Beatrice Nolan, Jamie O'Hara, Kate Khair
Introduction  Limited data relating to treatment burden, quality of life, and mental health burden of hemophilia A (HA) are currently available. Aim  To provide a comprehensive overview of unmet needs in people with HA (PwHA) using data generated from the Cost of Haemophilia in Europe: a Socioeconomic Survey-II (CHESS II) and CHESS in the pediatric population (CHESS PAEDs) studies. Methods  CHESS II and CHESS PAEDs are cross-sectional surveys of European males with HA or hemophilia B (HB) aged ≥18 and ≤17 years, respectively...
April 2024: TH Open: Companion Journal to Thrombosis and Haemostasis
https://read.qxmd.com/read/38628280/post-traumatic-growth-in-oncological-patients-during-the-covid-19-pandemic
#22
JOURNAL ARTICLE
Letizia Lafuenti, Loredana Dinapoli, Ludovica Mastrilli, Vezio Savoia, Marinella Linardos, Riccardo Masetti, Giampaolo Tortora, Vincenzo Valentini, Giovanni Scambia, Daniela P R Chieffo
BACKGROUND: Post-traumatic growth (PTG) is defined as "positive psychological change experienced as a result of the struggle with highly challenging life circumstances". Diagnosis of cancer leads to many psychological challenges. The recent pandemic forced oncological patients to face other multiple stressors. Resilience is a target of interest for PTG. The aim of this study is to analyze relationships between cancer trauma, COVID-19 pandemic stress, PTG and resilience over time. PARTICIPANTS AND PROCEDURE: One hundred forty-six patients (124 females, 22 males) in active oncological treatment were enrolled from September 2020: 45...
2024: Health Psychology Report
https://read.qxmd.com/read/38627891/discovering-needs-for-palliative-care-in-children-with-cancer-in-indonesia
#23
JOURNAL ARTICLE
Alexandra Widita Swipratami Pangarso, Sri Mulatsih, Mei Neni Sitaresmi, Susanne Verhulst, Gertjan Kaspers, Saskia Mostert
BACKGROUND: Although most children with cancer die in low- and middle-income countries, palliative care receives limited attention in these settings. This study explores parents' perspectives on experiences and needs of children dying from cancer. METHODS: Home visits were conducted to interview parents of children, who were treated for cancer at an Indonesian academic hospital and died between 2019 and 2020, using semi-structured questionnaires. RESULTS: Parents of 49 children (response rate 74%) were interviewed...
April 16, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38627837/schema-therapy-versus-treatment-as-usual-for-outpatients-with-difficult-to-treat-depression-study-protocol-for-a-parallel-group-randomized-clinical-trial-depre-st
#24
JOURNAL ARTICLE
Ida-Marie T P Arendt, Matthias Gondan, Sophie Juul, Lene Halling Hastrup, Carsten Hjorthøj, Bo Bach, Poul Videbech, Martin Balslev Jørgensen, Stine Bjerrum Moeller
BACKGROUND: About one third of patients with depression are in a condition that can be termed as "difficult-to-treat". Some evidence suggests that difficult-to-treat depression is associated with a higher frequency of childhood trauma and comorbid personality disorders or accentuated features. However, the condition is understudied, and the effects of psychotherapy for difficult-to-treat depression are currently uncertain. The aim of this trial is to investigate the beneficial and harmful effects of 30 sessions of individual schema therapy versus treatment as usual for difficult-to-treat depression in the Danish secondary, public mental health sector...
April 16, 2024: Trials
https://read.qxmd.com/read/38626791/-oncological-rehabilitation-for-breast-cancer
#25
JOURNAL ARTICLE
Holger G Hass
As a result of increasingly individualized and multimodal therapy, prognosis of breast cancer has improved significantly over the last years. However, multimodal treatment and the use of new medications can lead to a variety of somatic, sometimes new, side effects such as fatigue, polyneuropathy or autoimmune toxicities. This and the oncological diagnosis lead to a high level of psychological distress in the women affected and often to subsequent psychological disorders (sleep/anxiety disorders, depression, ...
April 2024: Die Rehabilitation
https://read.qxmd.com/read/38623813/eliciting-the-views-of-left-breast-cancer-patients-receiving-deep-inspiration-breath-hold-radiation-therapy-to-inform-the-design-of-multimedia-education-and-improve-patient-centred-care-for-prospective-patients
#26
JOURNAL ARTICLE
Kathleene Dower, Georgia K B Halkett, Haryana Dhillon, Diana Naehrig, Moira O'Connor
INTRODUCTION: The currently accepted best practice radiation treatment for left breast cancer patients is Deep Inspiration Breath Hold (DIBH) where patients hold a deep breath to reduce late cardiac and pulmonary effects from treatment. DIBH can be challenging and induce or exacerbate anxiety in patients due to the perceived pressure to reduce radiation treatment side effects. This study explored the experiences of patients treated with Deep Inspiration Breath Hold Radiation Therapy (DIBH-RT) to improve patient-centred care and inform the design of multimedia educational tools for future patients undergoing DIBH...
April 16, 2024: Journal of Medical Radiation Sciences
https://read.qxmd.com/read/38623042/-everywhere-i-call-there-s-nothing-available-understanding-the-alcohol-treatment-landscape-and-needs-among-unstably-housed-people-who-use-alcohol-in-rhode-island
#27
JOURNAL ARTICLE
Alexandra B Collins, Michael Tan, Megan Smith, Sara J Becker
INTRODUCTION: Alcohol is a leading cause of morbidity and mortality in the United States and people who are unstably housed are disproportionately impacted by adverse alcohol-related health outcomes. Addressing the needs of unstably housed people with high-intensity alcohol use (i.e., heavy episodic use or binge drinking), including those whose goal is not abstinence, is critical to reducing harms among this population. This study explores the alcohol-related treatment and support needs among unstably housed people who use alcohol...
April 16, 2024: Drug and Alcohol Review
https://read.qxmd.com/read/38622674/the-cost-effectiveness-of-early-intervention-mbt-early-versus-standard-protocolized-treatment-cbt-for-emerging-borderline-personality-disorder-in-adolescents-the-early-study-a-study-protocol-for-a-randomized-controlled-trial
#28
JOURNAL ARTICLE
Melissa G A Remeeus, Sharon L Clarke, Dine J Feenstra, Hester Van Eeren, Maaike L Smits, Sara Debruyne, Mirjam E J Kouijzer, Patrick Luyten, Ron H J Scholte, Joost Hutsebaut
BACKGROUND: Although clinical guidelines prioritize the treatment of depression and anxiety in young persons, there is accumulating evidence that the presence of symptoms of borderline personality disorder (BPD) is associated with the limited effectiveness of these standard treatments. These findings stress the need for interventions addressing early-stage BPD in young people with presenting symptoms of anxiety and depressive disorders. The aim of this study is to investigate the (cost-)effectiveness of an early intervention programme for BPD (MBT-early) compared to first-choice psychological treatment for depression and anxiety according to Dutch treatment guidelines (CBT), in adolescents with either depression, anxiety, or both, in combination with early-stage BPD...
April 15, 2024: Trials
https://read.qxmd.com/read/38622009/solution-focused-group-counseling-on-mental-states-in-hemodialysis-patients-with-anxiety
#29
JOURNAL ARTICLE
Peipei Chen, Dandan Lin
BACKGROUND: Hemodialysis patients usually suffer from anxiety due to physical and social factors, which belongs to a kind of psychological disorder, easily contributing to the decrease of patients' adherence to the treatment, and seriously affecting the patients' health status and quality of life. Solution-focused group counseling (SFGC) is a kind of psychotherapy proven to improve emotional problems in many fields. Still, the application of this therapy is rare in medical situations...
April 2024: Actas Españolas de Psiquiatría
https://read.qxmd.com/read/38621020/perceptions-of-general-practitioners-towards-managing-dental-presentations-in-australia-a-qualitative-study
#30
JOURNAL ARTICLE
Ruby Biezen, Angel Leong, Leanne Teoh
Background Patients presenting with dental pain are common in general practice, despite dental infections being most appropriately managed with dental treatment to address the cause of the infection. Although antibiotics are not appropriate for the management of localised toothache without signs of systemic spread, general practitioners (GPs) often prescribe antibiotics and analgesics for the management of dental pain. The aim of this study was to explore GPs' perceptions and management of dental presentations in Australia...
April 2024: Australian Journal of Primary Health
https://read.qxmd.com/read/38619754/predictors-of-impairment-and-self-concept-in-children-and-adolescents-with-persistent-tic-disorder
#31
JOURNAL ARTICLE
Kirsten R Bootes, Michael B Himle, Jordan T Stiede, Brianna C M Wellen, Suzanne Mouton-Odum, Douglas W Woods
This study examined predictors of, and associations between, self-concept, demographic variables, and clinical measures in fifty-eight children and adolescents with Persistent Tic Disorder (PTD; 44 males, Mage  = 11.9 years, SD = 2.74). Participants completed measures that assessed self-concept, tic severity, tic-related impairment, and comorbid psychological symptoms. Results showed that generalized anxiety disorder, major depressive disorder, persistent depressive disorder, total tic severity, number and complexity of tics, and total and social tic-related impairment were associated with self-concept...
April 15, 2024: Child Psychiatry and Human Development
https://read.qxmd.com/read/38616413/prolonged-exposure-treatment-for-post-traumatic-stress-disorder-single-case-studies-in-a-sample-of-adults-with-mild-intellectual-disabilities
#32
JOURNAL ARTICLE
Paul Prins, Karin Nijhof
BACKGROUND: Post-traumatic stress disorder (PTSD) is common in adults with intellectual disabilities. Often there are additional disorders such as substance use, mood and anxiety disorders. The current study focuses on the feasibility and initial efficacy of prolonged exposure (PE) for PTSD in adults with mild intellectual disabilities. The secondary effect of PE on additional mood, anxiety and substance use disorders is also examined. METHODS: A single case experimental design (N = 12) with an A (baseline)-B (intervention) phase including a follow-up measurement after 3 months was conducted...
May 2024: Journal of Applied Research in Intellectual Disabilities: JARID
https://read.qxmd.com/read/38616339/a-web-based-survey-on-the-occurrence-of-emotional-blunting-in-patients-with-major-depressive-disorder-in-japan-patient-perceptions-and-attitudes
#33
JOURNAL ARTICLE
Toshiaki Kikuchi, Jun-Ichi Iga, Masato Oosawa, Tatsuya Hoshino, Yoshiya Moriguchi, Miwa Izutsu
AIMS: To determine the prevalence and impact of emotional blunting (EB) in patients with major depressive disorder (MDD) in Japan, and identify treatment needs for EB using patients' perceptions and attitudes. METHODS: Eligible patients in Japan (aged 18-59 years) who reported a diagnosis of MDD and antidepressant medication use for >3 months were eligible to complete an online survey. The primary outcome was the prevalence of EB, self-reported using a validated screening question...
April 14, 2024: Neuropsychopharmacology Reports
https://read.qxmd.com/read/38614224/the-oxytocin-receptor-is-essential-for-the-protective-effect-of-pair-housing-on-post-stroke-depression-in-mice
#34
JOURNAL ARTICLE
Su-Ting Jiang, Shu-Ying Lian, Yao-Huan Sun, Mei-Bo Pan, Bin Wang, Hui Wang, Jun Hua, Yi-Chen Wang, Qiu-Ling Wang, Yin-Feng Dong
The beneficial effect of social interaction in mitigating the incidence of post-stroke depression (PSD) and ameliorating depressive symptoms has been consistently demonstrated through preclinical and clinical studies. However, the underlying relationship with oxytocin requires further investigation. In light of this, the present study aimed to explore the protective effect of pair housing on the development of PSD and the potential relationship with oxytocin receptors. The PSD model was induced by middle cerebral artery occlusion (MCAO) for 50 min, followed by 4-week isolated housing and restrained stress...
April 11, 2024: Experimental Gerontology
https://read.qxmd.com/read/38610833/emotional-and-behavioral-impairment-and-comorbid-eating-disorder-symptoms-in-adolescents-with-obesity-a-cross-sectional-study
#35
JOURNAL ARTICLE
Anna Guerrini Usubini, Michela Bottacchi, Adele Bondesan, Francesca Frigerio, Nicoletta Marazzi, Gianluca Castelnuovo, Alessandro Sartorio
Background : The current study aims to assess the psychological conditions of Italian adolescents with obesity seeking an in-hospital multidisciplinary body weight reduction program, by exploring their psychological adjustment, emotional states, and co-occurring eating disorder symptoms. Methods : The study involved ninety-two consecutive Italian adolescents with obesity (31 males, 61 females), with a mean age ± SD: 16.4 ± 1.1 years and body mass index (BMI): 38.3 ± 6.04 kg/m2 ). The Strengths and Difficulties Questionnaire (SDQ), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and Eating Attitude Test-26 (EAT-26) were used for the evaluations...
April 3, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38608740/cannabidiol-improves-maternal-obesity-induced-behavioral-neuroinflammatory-and-neurochemical-dysfunctions-in-the-juvenile-offspring
#36
JOURNAL ARTICLE
Fernanda da Silva Rodrigues, Jeferson Jantsch, Gabriel de Farias Fraga, Vitória Luiza de Camargo Milczarski, Victor Silva Dias, Camila Scheid, Josias de Oliveira Merib, Marcia Giovernardi, Renata Padilha Guedes
Maternal obesity is associated with an increased risk of psychiatric disorders such as anxiety, depression, schizophrenia and autism spectrum disorder in the offspring. While numerous studies focus on preventive measures targeting the mothers, only a limited number provide practical approaches for addressing the damages once they are already established. We have recently demonstrated the interplay between maternal obesity and treatment with cannabidiol (CBD) on hypothalamic inflammation and metabolic disturbances, however, little is known about this relationship on behavioral manifestations and neurochemical imbalances in other brain regions...
April 10, 2024: Brain, Behavior, and Immunity
https://read.qxmd.com/read/38607194/influence-of-local-vibration-therapy-on-the-mental-state-neurological-function-and-quality-of-life-of-convalescing-patients-with-spinal-cord-injury
#37
JOURNAL ARTICLE
Xiaoqian Zheng, Lei Wang, Liping Meng, Zhenzhen Xu
CONTEXT: The clinical postoperative recovery of patients with a spinal cord injury (SCI) is relatively long. Good self-efficacy can help patients actively cooperate with treatment and rehabilitation and improve their functional recovery and QoL. Local vibration stimulation has emerged as a potential nondrug therapy for SCI patients. However, the use of local vibration therapy for SCI patients is still rare, and its efficacy isn't clear yet. OBJECTIVE: The study intended to analyze the combined effects of local vibration therapy and self-efficacy training on the psychological state and neurological function of SCI patients during rehabilitation as well as the therapy's correlation with quality of life (QoL)...
April 12, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38606582/the-effectiveness-and-safety-of-dialectical-behavior-therapy-for-suicidal-ideation-and-behavior-in-autistic-adults-a-pragmatic-randomized-controlled-trial
#38
JOURNAL ARTICLE
Anne Huntjens, L M C Wies van den Bosch, Bram Sizoo, Ad Kerkhof, Filip Smit, Mark van der Gaag
BACKGROUNDS: Many autistic people in mental health are suicidal. This study evaluated the effectiveness of dialectical behavior therapy (DBT) v. treatment as usual (TAU) in reducing suicidal ideation and suicide attempts. METHODS: At six Dutch mental health centers, 123 outpatients (18-65 years) with DSM-5 diagnosed autism spectrum disorder (ASD) and suicidal behavior were randomly assigned to the DBT intervention group ( n = 63) or TAU control group ( n = 60). Assessments were conducted at baseline, post-treatment at 6 months and 12-month follow-up...
April 12, 2024: Psychological Medicine
https://read.qxmd.com/read/38605386/cancer-survivorship-understanding-the-patients-journey-and-perspectives-on-post-treatment-needs
#39
JOURNAL ARTICLE
Conor Hussey, Moira Hanbridge, Maura Dowling, Ananya Gupta
BACKGROUND: Cancer treatments have many adverse effects on patient's health leading to poor cardiorespiratory capacity, muscular- degeneration, fatigue, loss of strength and physical function, altered body-composition, compromised immune-function, peripheral neuropathy, and reduced quality of life (QOL). Exercise programs can significantly increase functional capacity when tailored to individual needs, thus improving health. Exercise interventions in cancer rehabilitation, when supported by appropriate nutrition can be effective in attaining a healthy weight and body-composition...
April 12, 2024: BMC Sports Science, Medicine and Rehabilitation
https://read.qxmd.com/read/38605013/the-predictive-value-of-cortisol-in-psychodynamic-psychotherapy-for-social-anxiety-disorder-extended-results-of-the-sophonet-study
#40
JOURNAL ARTICLE
Ileana Schmalbach, Michael Witthöft, Bernhard Strauß, Peter Joraschky, Katja Petrowski
Psychotherapy is an effective treatment for anxiety disorders (AD), yet a vast majority of patients do not respond to therapy, necessitating the identification of predictors to enhance outcomes. Several studies have explored the relationship between stress response and treatment outcome, as a potential treatment mechanism. However, the latter remains under-researched in patients with social anxiety disorder (SAD). We studied N = 29 patients undergoing psychodynamic psychotherapy (PDT) within the SOPHONET-Study...
April 11, 2024: Translational Psychiatry
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